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Overview
Quickly Capture
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Strikingly Clear Confocal ImagesWith a Yokogawa CSU-W1 spinning disk unit, the IXplore™ IX85-Spin system helps you acquire high-speed confocal images and conduct more efficient image stitching over a wide area. To help you see even more, TruSight deconvolution algorithms can be applied to improve image resolution, contrast, and dynamic range for strikingly clear 3D images, even at greater observation depths. | *Image: NIH 3T3 cells (Blue: Nuclei, Green: Tubulin, Magenta: Mitochondria, Gray: Fibrillarin)
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Precise 3D Image Generation at Greater DepthsThe pinhole geometry of the IXplore™ IX85-Spin system’s Yokogawa spinning disk produces excellent image contrast at greater depths for imaging into thicker samples. Additionally, the IXplore™ IX85-Spin allows you to combine high-NA silicone oil objectives or our new groundbreaking silicone gel multi-immersion objective (LUPLAPO25XS) with a new auto correction collar to create exceptional light gathering and dimensional fidelity. These elements make the IXplore™ IX85-Spin your best choice for imaging live cells at high resolution without sacrificing speed, accuracy, or image quality. Our new LUPLAPO25XS introduces groundbreaking new silicone gel pad technology. See deeper into your samples and reveal structures that were previously out of reach with a high NA and long working distance. With this silicone gel pad objective, you can get the quality of silicone immersion with the useability of a dry objective. The new LUPLAPO25XS enhances workflows for organoids, 3D cell culture, well-plates, and a wide range of applications. | |
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XYZ image comparison between Left: LUPLAPO25XS (Silicone gel) and Right: UPLXAPO20X (Dry)
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Simultaneous High-Speed Multichannel ImagingThe IXplore™ IX85-Spin laser combiner is scalable from two to six laser lines, and multi-camera configuration is available to support simultaneous multichannel imaging if you require higher speed or a wider information bandwidth. Excitation wavelengths include 405nm, 445nm, 488nm, 514nm, 561nm, and 640nm. | Cultured Cos 7 cell
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IXplore™ IX85 Automated Inverted Microscope SystemThe foundation of our IXplore™ IX85-Spin system, the IXplore™ IX85 delivers the largest FOV in the industry and an array of advanced end-to-end imaging features, allowing you to see and capture more than ever before while dramatically reducing acquisition times. Experience exceptional speed, clarity, and reliability with the IXplore™ IX85 microscope system. |
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See How Evident Microscopes with Spinning Disk Confocal Technology Have Been Used in Life Science ResearchN. Elkhatib, et al. Tubular clathrin/AP-2 lattices pinch collagen fibers to support 3D cell migration. Science (June 16, 2017). R. H. Herbst, et al. Heterosis as a consequence of regulatory incompatibility. BMC Biology (May 11, 2017). N. Yanagisawa, et al. Capability of tip-growing plant cells to penetrate into extremely narrow gaps (May 3, 2017). H. Cohen-Dvashi, et al. The role of LAMP1 binding and pH sensing by the spike complex of Lassa virus. Journal of Virology (September 7, 2016). H. Ochiai, et al. Simultaneous live imaging of the transcription and nuclear position of specific genes. Nucleic Acids Research (June 19, 2016). B. Guirao, et al. Unified quantitative characterization of epithelial tissue development. eLIFE (December 12, 2015). I. Nemazanyy, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nature Communications (September 21, 2015). K. Gooh, et al. Live-cell imaging and optical manipulation of arabidopsis early embryogenesis. Developmental Cell (July 9, 2015). Y. Oda, et al. Rho of plant GTPase signaling regulates the behavior of arabidopsis kinesin-13A to establish secondary cell wall patterns. The Plant Cell (November 26, 2013). |
*1 Although it became one of the most important cell lines in medical research, it’s imperative that we recognize Henrietta Lacks’ contribution to science happened without her consent. This injustice, while leading to key discoveries in immunology, infectious disease, and cancer, also raised important conversations about privacy, ethics, and consent in medicine.
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Specifications
IX85-Spin | ||
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Laser Lines | 405 nm 50mW, 445 nm 75mW, 488 nm 100mW, 514 nm 40mW, 561 nm 100mW, 640 nm 100mW | |
Laser Combiner |
Main combiner: 405 nm, 488 nm, 561 nm, 640 nm + 1 line (445 nm or 514 nm)
Sub combiner: 445 nm, 514 nm 2x Interlock shutter available | |
Laser Light Control | Direct modulation, ON/OFF control and intesity modulation with individual laser lines | |
Scanner | Yokogawa CSU-W1 | Single 50 μm pinhole disk, 1 or 2 camera model |
Acquisition Speed (Max.) | 5ms/f | |
Optical Zoom | 1x | |
Field Number | 22 | |
Dichromatic Mirror | 3 position (motorized slider) | |
Filter Wheel (emission) | 10 position (motorized wheel) | |
Imaging Sensor | 3rd party sCMOS Cameras | |
Microscope | IX85P1ZF | |
Imaging Software | cellSens Dimension; Multi-dimensional acquisition and analysis | |
Operating enviornment |
• Indoor use
• Ambient temperature: 5 ºto 40 ºC (41 º to 104 ºF) • Maximum relative humidity: 80% for temperatures up to 31 ºC (88 ºF), decreasing linearly through 70% at 34 ºC (93 ºF), 60% at 37 º C (99 ºF), to 50% relative humidity at 40 ºC (104 ºF) • Supply voltage fluctuations: Not to exceed ±10% of the normal voltage |