Life Science Solutions

Webinar: Introducing Upconversion Nanoparticles for Fluorescence Microscopy

Introducing Upconversion Nanoparticles for Fluorescence Microscopy

Lanthanide-based upconversion nanoparticles (UCNP) have emerged as a new type of fluorescent probes offering unique optical properties for microscopy imaging. However, such uniqueness also means they are not readily applicable to standard fluorescence microscopy, which has been a barrier to their adoption in life sciences. In this webinar, you will learn about the basics of UCNPs and the minimum modification to standard instruments to be able to observe them. We will also discuss their multiplexing capability of detecting and analysing multiple targets of interest, as well as their potential for excitation by light-emitting diodes (LEDs) to avoid pains to address laser safety issues. The advantages and benefits of UCNPs for fluorescence microscopy opens doors to new research and applications for biomedical and molecular scientists.


  1. An introduction to UCNPs
  2. Using UCNPs in wide-field and confocal microscopy
  3. Multiplexing imaging with UCNPs
  4. Illuminating UCNPs by light-emitting diodes
  5. Conclusions and outlook


Presenter Dr. Yiqing Lu

Dr. Yiqing Lu, ARC Centre for Nanoscale BioPhotonics (CNBP)
School of Engineering Macquarie University, Sydney, Australia
Dr Yiqing Lu obtained his Bachelor degree in Electronic Engineering from Tsinghua University. China, followed by a cotutelle PhD between Tsinghua and Macquarie University on optoelectronic sensing and imaging. This was followed by research in the Department of Physics and Astronomy at Macquarie in the cross-disciplinary area of nano-bio-photonics (Macquarie University Research Fellowship and an ARC DECRA Fellowship), before joining its School of Engineering in 2020. His research is centred on the design and engineering of luminescent nanomaterials in conjunction with detection instruments for analytical and biomedical applications. Over 40 peer-reviewed journal articles and conference proceedings, including first/corresponding-author papers in Nature, Nature Photonics and Nature Nanotechnology, with total citations ~2,000. He serves as reviewer for a range of scientific journals such as Nature Communications, Nanoscale, Biomaterials, Science Bulletin, Journal of Biophotonics, Frontiers in Chemistry and Optics Letters.


Moderator Dr Sandrine Roy

Dr Sandrine Roy, High End Microscopy
Olympus Australia
Sandrine recently joined Olympus Australia High End Microscopy team. Prior to this position, Sandrine managed the UQDI/TRI microscopy core facility for 10 years. Under her care, the facility was a successful and well-regarded core facility with an excellent reputation for user support, training and a high level of scientific knowledge in highly technical instrumentation, data analysis and education. Customer support has always been her passion and her position at Olympus allows her to thrive in this passion.

Register now:

July 8, 2020 4p.m. - 5p.m. (AEST)

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