Total internal reflection fluorescence microscopy (TIRFM) has firmly established itself over the last few years as a key technique in the investigation of molecular interactions at or near the cell surface. Olympus is experienced in providing advanced TIRFM solutions and cellTIRF takes this to the next level with a series of peerless features such as highly advanced optics, unique independent laser control and exceptional accuracy. The cellTIRF system is easy to use for TIRFM, HILO microscopy
and point FRAP for a range of experimental protocols.
Electron multiplying CCD cameras amplify optical signals without increasing noise. They can capture high-speed images of dim specimens and perform well for fluorescence live-cell imaging with reduced intensity excitation light. They are used to observe protein interaction within a cell and for real-time imaging.
CCD technology for detecting ultra-low light
Dedicated, ultrasensitive scientific camera platform
Scientific CMOS (sCMOS) cameras are optimized for live cell imaging, providing lower noise and improved quantum efficiency compared with conventional CMOS devices. Capabilities of sCMOS cameras include a high-speed response, wide dynamic ranges, an extended field-of-view, high resolution, and gradation.
Extremely fast readout for high speed
Designed for applications that demand high resolution
High signal-to-noise images for live cell imaging applications
