Life Science Solutions


enero 07, 2020

Innovative Incubation Monitoring System with Cell Count and Confluency Analysis to Improve the Regenerative Medicine Workflow

Track the health of cell cultures without removing them from the incubator

The OLYMPUS Provi CM20 incubation monitoring system* provides quantitative data about the health of cell cultures while they are in the incubator. The system periodically scans the cultures, counts the number of cells, determines confluency and wirelessly communicates the data to a tablet or PC. By using the CM20 system, you can acquire data that will help improve the reproducibility and stability of your cell culture process.

incubation monitoring system

OLYMPUS Provi CM20  incubation monitoring system

Cultivating cell cultures can be costly, complicated and time-consuming since it involves multiple steps and careful timing. The CM20 incubation monitoring system improves quality management and reduces the amount of labor involved in the cell culture process through three key values.

Label-free, quantitative data

The system automatically scans multiple points in a culture vessel to provide a steady stream of quantitative data about the health and confluency of cultures. You can keep track of your cell cultures’ health while they remain safely in the incubator, which reduces the risk of damage caused by temperature change, vibration, or contamination. There is also no need to stain or peel the cultures to check their status since the system acquires data from label-free cells. It has a thin, compact design, and can be installed in confined spaces.

Label-free, quantitative data

Sample images of induced pluripotent stem (iPS) cells  Left: raw image, Right: analysis image

Sample images of induced pluripotent stem (iPS) cells
Left: raw image, Right: analysis image

Consistent results throughout your lab

With a digital record of cell growth and health, you can store, reuse and transfer your data, compare it with past results or compare it with data captured under different conditions. In a project that multiple people are working on or when training new people, the CM20 system makes it simple for managers to check the team’s culture status.

Comparison of confluency

Comparison of confluency
Purple: vessel #1  , Blue: vessel #2
You can easily tell the difference in confluency between the two vessels

Cost effective

Remote cell culture monitoring reduces the associated operational costs incurred whenever someone enters the clean room to check the cultures’ status manually. Users can even set up the system to send an alert when their cultures approach confluency and are ready for passage, reducing the risk of loss caused by mistiming cell passage.

Cost effective

With proven experience in regenerative medicine and expertise in optics, image analysis and data management, Olympus is uniquely positioned to help empower users to push the boundaries of regenerative medicine.

*The OLYMPUS Provi CM20 incubation monitoring system is currently only available in Japan and the United States.

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