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The A-549 cell line was originally cultivated in 1972 by D. J. Giard, along with several collaborators, from the human lung carcinoma of a 58-year-old Caucasian male. The line is commonly used to investigate a wide range of respiratory ailments, such as viral infections capable of inducing asthma, tissue damage linked to asbestos exposure, and smoking-related emphysema.
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