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Phase contrast and DIC observations are sometimes used in this application. If you don’t need color information, a monochrome camera is a good choice since it can also be used for fluorescence.

Pixel size (μm)
3.45 x 3.45 µm2.4 × 2.4 μm2.4 × 2.4 μm
Number of pixels (MP)
Image Sensor
1 in. color CMOS1/1.8 inch Color CMOS1/1.8 inch Backside illuminated monochrome CMOS
Frame rate (fps)
at max resolution

Max.32 fps at 4104 × 2174 (Full Resolution)
Max.33 fps at 3840 × 2160 (4K)
Max.33 fps at 2168 × 2168 (Square) 
Max.64 fps at 1920 × 1080 (Full HD) *1

Max.45 fps at 3088 × 2076 (Full Resolution)
Max.58 fps at 2072 × 2072 (Square)
Max.60 fps at 1920 × 1080 (Full HD) *1

Up to 45 fps at 3088 × 2076 pixels
Up to 58 fps at 2072 × 2072 pixels (Square)
Up to 60 fps at 1920 × 1080 pixels (Full HD 16:9)
Up to 58 fps at 1544 × 1038 pixels (Binning 2 × 2)

Frame rate may decrease depending on the condition of your PC, resolution of your monitor, and/or software.

USB 3.1 Gen1 *2USB 3.1 Gen1 *2USB 3.1 Gen1*
  • Color
  • Color
  • Monochrome
Observation Method
  • Brightfield
  • Fluorescence
  • Brightfield
  • Fluorescence
  • Fluorescence

Focus Peaking manual focus assist
OSIA - Olympus Smart Image Averaging (active noise reduction)
*USB 3.1 Gen1 is compatible with USB 3.0

Focus Peaking manual focus assist
OSIA - Olympus Smart Image Averaging (active noise reduction)
​*USB 3.1 Gen1 is compatible with USB 3.0

  • Compatible PC Specifications - CPU: Intel® Xeon, Intel® Core i5, i7, i9 or the equivalent RAM: 8 GB
  • Imaging Platform - cellSens Entry, Standard, and Dimension, v. 3.2 or higher**; Service update for v. 3.2 required. PC Control Windows 10 64-bit
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DP28 DP23 DP23M 
Observation Method
Cameras must have good sensitivity and low noise because strong excitation light can damage the sample. Although the signal yield is determined by simple physics (i.e., sensitivity × number of photons), some cameras, like the DP74, have a dedicated feature to shorten and simplify the fluorescence imaging process.
Accurate color reproduction is essential. Since modern microscope illumination is very bright, it’s rare to struggle with noise in brightfield images.
Phase Contrast/DIC
For phase contrast or differential interference contrast (DIC), the DP22 and DP27 have a color mode dedicated to imaging cultured cells.
Many cameras designed for brightfield observation also work well for polarization due to their accurate color reproduction, such as the DP27 and SC50.
Darkfield is the second darkest microscope observation method, so cameras with high sensitivity and low noise are essential. Many of our cameras, including the DP74, UC90, and SC50, feature special noise reduction image processing for excellent darkfield images.
Microscope image resolution is determined by the resolution of the optics and the camera. The UC90 and SC180 4K cameras provide excellent resolution at low magnification (4x and 10x) or for stereo microscopes where the camera’s resolution is so important.
A high frame rate is essential for obtaining smooth live images. Other important features include image lag and shutter type (i.e., rolling or global). The DP74 camera provides a fast 60 frames per second frame rate and delivers images with minimal distortion thanks to its global shutter CMOS sensor.
Framerate is less important when capturing still images, but resolution, the field of view, and color reproduction are still essential. While all our cameras work well for capturing still images, choose the camera that’s right for you based on the above characteristics.

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