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New
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
Cell BiologyOut 26 2018Nature Communications

Shin Murai, Yoshifumi Yamaguchi, Yoshitaka Shirasaki, Mai Yamagishi, Ryodai Shindo, Joanne M. Hildebrand, Ryosuke Miura, Osamu Nakabayashi, Mamoru Totsuka, Taichiro Tomida, Satomi Adachi-Akahane, Sotaro Uemura, John Silke, Hideo Yagita, Masayuki Miura & Hiroyasu Nakano

New
Mutual inhibition between PTEN and PIP3 generates bistability for polarity in motile cells
Cell BiologyOut 26 2018Nature Communications

Satomi Matsuoka & Masahiro Ueda

New
Phospholipid flippases enable precursor B cells to flee engulfment by macrophages
Cancer & ImmunologyOut 24 2018PNAS

Katsumori Segawa, Yuichi Yanagihashi, Kyoko Yamada, Chigure Suzuki, Yasuo Uchiyama, and Shigekazu Nagata

New
Uncoupled deposition of secondary wall polymers
Plant & Animal ScienceOut 18 2018The Plant Cell

Yuto Takenaka, Yoichiro Watanabe, Mathias Schuetz, Faride Unda, Joseph Lee Hill, Pawittra Phookaew, Arata Yoneda, Shawn D. Mansfield, A. Lacey Samuels, Misato Ohtani, Taku Demura

New
Myoferlin-Mediated Lysosomal Exocytosis Regulates Cytotoxicity by Phagocytes
Cancer & ImmunologyOut 17 2018The Journal of Immunology

Yuji Miyatake, Tomoyoshi Yamano and Rikinari Hanayama

New
ROSA26 reporter mouse lines and image analyses reveal the distinct region-specific cell behaviors in the visceral endoderm
Developmental BiologyOut 16 2018Development

Takaya Abe, Natsumaro Kutsuna, Hiroshi Kiyonari, Yasuhide Furuta, Toshihiko Fujimori

New
Shootin1b Mediates a Mechanical Clutch to Produce Force for Neuronal Migration
NeuroscienceOut 16 2018Cell Reports

Takunori Minegishi, Yasuyuki Uesugi, Naoko Kaneko, Wataru Yoshida, Kazunobu Sawamoto, Naoyuki Inagaki

New
Endocytic trafficking factor VPS45 is essential for spatial regulation of lens fiber differentiation in zebrafish
Developmental BiologyOut 15 2018Development

Toshiaki Mochizuki, Yutaka Kojima, Yuko Nishiwaki, Tetsuya Harakuni, Ichiro Masai

New
Color opponency with a single kind of bistable opsin in the zebrafish pineal organ
NeuroscienceOut 15 2018PNAS

Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Masahiko Hibi, Satoshi Tamotsu, Mitsumasa Koyanagi, and Akihisa Terakita

New
Impacts of Diabetes and an SGLT2 Inhibitor on the Glomerular Number and Volume in db/db Mice, as Estimated by Synchrotron Radiation Micro-CT at SPring-8
Biomedical ResearchOut 12 2018EBioMedicine

Yumi Takiyama, Toshihiro Sera, Masanori Nakamura, Kanaki Ishizeki, Yasuaki Saijo, Tsuyoshi Yanagimachi, Manami Maeda, Ryoichi Bessho, Takao Takiyama, Hiroya Kitsunai, Hidemitsu Sakagami, Daisuke Fujishiro, Yukihiro Fujita, Yuichi Makino, Atsuko Abiko, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Tsuguhito Ota, Masakazu Haneda

New
A biological switching valve evolved in the female of a sex-role reversed cave insect to receive multiple seminal packages
Plant & Animal ScienceOut 12 2018eLife

Kazunori Yoshizawa, Yoshitaka Kamimura, Charles Lienhard, Rodrigo L Ferreira, Alexander Blanke

New
NDP52 interacts with mitochondrial RNA poly (A) polymerase to promote mitophagy
Biochemistry & Molecular BiologyOut 11 2018EMBO Reports

Norihiko Furuya, Soichiro Kakuta, Katsuhiko Sumiyoshi, Maya Ando, Risa Nonaka,Ayami Suzuki, Saiko Kazuno, Shinji Saiki, Nobutaka Hattori

New
Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex
NeuroscienceOut 11 2018Cerebral Cortex

Keiko Nakanishi  Hiroyuki Niida  Hidenori Tabata  Tsuyoshi Ito  Yuki Hori Madoka Hattori  Yoshikazu Johmura  Chisato Yamada  Takashi Ueda  Kosei Takeuchi Kenichiro Yamada  Koh-ichi Nagata  Nobuaki Wakamatsu  Masashi Kishi  Y Albert Pan Shinya Ugawa  Shoichi Shimada  Joshua R Sanes  Yujiro Higashi  Makoto Nakanishi

New
The Pace of Neurogenesis Is Regulated by the Transient Retention of the Apical Endfeet of Differentiating Cells
NeuroscienceOut 11 2018Cerebral Cortex

Jun Hatakeyama, Kenji Shimamura

New
Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response
Cancer & ImmunologyOut 09 2018mBio

Hironori Bando, Youngae Lee, Naoya Sakaguchi, Ariel Pradipta, Ji Su Ma, Shun Tanaka, Yihong Cai, Jianfa Liu, Jilong Shen, Yoshifumi Nishikawa, Miwa Sasai, and Masahiro Yamamoto

New
Kinesin-binding–triggered conformation switching of microtubules contributes to polarized transport
Cell BiologyOut 08 2018The Journal of Cell Biology

Tomohiro Shima, Manatsu Morikawa, Junichi Kaneshiro, Taketoshi Kambara, Shinji Kamimura, Toshiki Yagi, Hiroyuki Iwamoto, Sotaro Uemura, Hideki Shigematsu, Mikako Shirouzu, Taro Ichimura, Tomonobu M. Watanabe, Ryo Nitta, Yasushi Okada, Nobutaka Hirokawa

New
Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus
Developmental BiologyOut 05 2018Development

Tomoko Watanabe, Takayoshi Yamamoto, Kohei Tsukano, Sayuki Hirano, Ayumi Horikawa, Tatsuo Michiue

New
RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability
Developmental BiologyOut 04 2018Developmental Cell

Shou Soeda, Kaori Yamada-Nomoto, Tatsuo Michiue, Miho Ohsugi

New
Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis
Developmental BiologyOut 03 2018Nature Communications

Chiharu Kimura-Yoshida, Kyoko Mochida, Masa-aki Nakaya, Takeomi Mizutani & Isao Matsuo

New
Application of the fluctuation theorem for non-invasive force measurement in living neuronal axons.
NeuroscienceOut 03 2018Molecular Psychiatry

Hikari Tanaka, Kanoh Kondo, Xigui Chen, Hidenori Homma, Kazuhiko Tagawa, Aurelian Kerever, Shigeki Aoki, Takashi Saito, Takaomi Saido, Shin-ichi Muramatsu, Kyota Fujita & Hitoshi Okazawa

New
Direct Relay Pathways from Lemniscal Auditory Thalamus to Secondary Auditory Field in Mice
NeuroscienceOut 01 2018Cerebral Cortex

Shinpei Ohga  Hiroaki Tsukano  Masao Horie  Hiroki Terashima  Nana Nishio Yamato Kubota  Kuniyuki Takahashi  Ryuichi Hishida  Hirohide Takebayashi Katsuei Shibuki

New
Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development
Cell BiologySet 27 2018PLoS Genetics

Taichi Hara, Ikuko Maejima, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, Satoshi Tsukamoto, Mika Tsunoda, Aguri Ono, Shota Yamakoshi, Satoshi Oikawa, Ken Sato

New
De novo PHACTR1 mutations in West syndrome and their pathophysiological effects
NeuroscienceSet 26 2018Brain

Nanako Hamada  Shunsuke Ogaya  Mitsuko Nakashima  Takuma Nishijo  Yuji Sugawara Ikuko Iwamoto  Hidenori Ito  Yuki Maki  Kentaro Shirai  Shimpei Baba  Koichi Maruyama Hirotomo Saitsu  Mitsuhiro Kato  Naomichi Matsumoto  Toshihiko Momiyama Koh-ichi Nagata

New
Crystal structure of the red light-activated channelrhodopsin Chrimson
Biochemistry & Molecular BiologySet 26 2018Nature Communications

Kazumasa Oda, Johannes Vierock, Satomi Oishi, Silvia Rodriguez-Rozada, Reiya Taniguchi, Keitaro Yamashita, J. Simon Wiegert, Tomohiro Nishizawa, Peter Hegemann & Osamu Nureki

New
mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility
Cell BiologySet 26 2018PLoS Biology

Satoko Sakamoto, Dean Thumkeo, Hiroshi Ohta, Zhen Zhang, Shuangru Huang, Pakorn Kanchanawong, Takayoshi Fuu, Sadanori Watanabe, Kentaro Shimada, Yoshitaka Fujihara, Shosei Yoshida, Masahito Ikawa, Naoki Watanabe, Mitinori Saitou, Shuh Narumiya

New
The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formation
Cell BiologySet 25 2018PNAS

Tetsuya Kotani, Hiromi Kirisako, Michiko Koizumi, Yoshinori Ohsumi, and Hitoshi Nakatogawa

New
Opposite roles in short-term plasticity for N-type and P/Q-type voltage-dependent calcium channels in GABAergic neuronal connections in the rat cerebral cortex
NeuroscienceSet 24 2018The Journal of Neuroscience

Kiyofumi Yamamoto and Masayuki Kobayashi

New
Retinal detachment-induced Müller glial cell swelling activates TRPV4 ion channels and triggers photoreceptor death at body temperature
NeuroscienceSet 24 2018The Journal of Neuroscience

Hidetaka Matsumoto, Shouta Sugio, François Seghers, David Krizaj, Hideo Akiyama, Yasuki Ishizaki, Philippe Gailly and Koji Shibasaki

New
The photosystem II repair cycle requires FtsH turnover through the EngA GTPase
Plant & Animal ScienceSet 21 2018Plant Physiology

Yusuke Kato, Kiwamu Hyodo, Wataru Sakamoto

New
Generation of human oogonia from induced pluripotent stem cells in vitro
Stem CellsSet 20 2018Science

Chika Yamashiro, Kotaro Sasaki, Yukihiro Yabuta, Yoji Kojima, Tomonori Nakamura, Ikuhiro Okamoto, Shihori Yokobayashi, Yusuke Murase, Yukiko Ishikura, Kenjiro Shirane, Hiroyuki Sasaki, Takuya Yamamoto, Mitinori Saitou

New
Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
Cancer & ImmunologySet 20 2018Cell

Takaaki Yasuhara, Reona Kato, Yoshihiko Hagiwara, Bunsyo Shiotani, Motohiro Yamauchi, Shinichiro Nakada, Atsushi Shibata, Kiyoshi Miyagawa

New
Regulatory cocktail for dopaminergic neurons in a protovertebrate identified by whole-embryo single-cell transcriptomics
Developmental BiologySet 18 2018Gene & Development

Takeo Horie, Ryoko Horie, Kai Chen, Chen Cao, Masashi Nakagawa, Takehiro G. Kusakabe, Noriyuki Satoh, Yasunori Sasakura, and Michael Levine

New
SIRT2‐mediated inactivation of p73 is required for glioblastoma tumorigenicity
Cancer & ImmunologySet 13 2018EMBO Reports

Kosuke Funato, Tomoatsu Hayashi, Kanae Echizen, Lumi Negishi, Naomi Shimizu, Ryo Koyama‐Nasu, Yukiko Nasu‐Nishimura, Yasuyuki Morishita, Viviane Tabar, Tomoki Todo, Yasushi Ino, Akitake Mukasa, Nobuhito Saito, Tetsu Akiyama

New
Repeated injection of KMRC011, a medical countermeasure for radiation, can cause adverse health effects in cynomolgus monkeys
PharmacologySet 11 2018Journal of Applied Toxicology

Hong‐Soo Lee, Yoo‐Jin Park, Doo‐Wan Cho, Su‐Cheol Han, Soo Youn Jun, Gi Mo Jung, Woo‐Jong Lee, Chi‐Min Choi, Eun‐Jung Park, Son‐Il Pak


  

New
Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity
Biomedical ResearchSet 11 2018Cell Reports

Ryutaro Ikegami, Ippei Shimizu, Takeshi Sato, Yohko Yoshida, Yuka Hayashi, Masayoshi Suda, Goro Katsuumi, Ji Li, Takayuki Wakasugi, Yasuhiko Minokoshi, Shiki Okamoto, Eiichi Hinoi, Søren Nielsen, Naja Zenius Jespersen, Camilla Scheele, Tomoyoshi Soga, Tohru Minamino

New
AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
Cell BiologySet 10 2018Nature Communications

Keisuke Ikawa & Kaoru Sugimura

New
TRPM2 exacerbates central nervous system inflammation in experimental autoimmune encephalomyelitis by increasing production of CXCL2 chemokines
NeuroscienceSet 10 2018The Journal of Neuroscience

Masato Tsutsui, Ryo Hirase, Sakie Miyamura, Kazuki Nagayasu, Takayuki Nakagawa, Yasuo Mori, Hisashi Shirakawa and Shuji Kaneko

New
Rational Design for Multicolor Flavone-Based Fluorophores with Aggregation-Induced Emission Enhancement Characteristics and Applications in Mitochondria-Imaging
Biochemistry & Molecular BiologySet 07 2018Molecules

Liyan Liu, Yaohui Lei, Jianhui Zhang, Na Li, Fan Zhang, Huaqiao Wang and Feng He

New
CAMSAP3 maintains neuronal polarity through regulation of microtubule stability
Developmental BiologySet 06 2018PNAS

Varisa Pongrakhananon, Hiroko Saito, Sylvain Hiver, Takaya Abe, Go Shioi, Wenxiang Meng, and Masatoshi Takeichi

New
Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance
Cell BiologySet 06 2018The Journal of Cell Biology

Akari Hagiwara, Yosuke Kitahara, Chad Paul Grabner, Christian Vogl, Manabu Abe, Ryo Kitta, Keisuke Ohta, Keiichiro Nakamura, Kenji Sakimura, Tobias Moser, Akinori Nishi, and Toshihisa Ohtsuka

New
Actin reorganization promotes root cell elongation
Plant & Animal ScienceSet 05 2018Plant Physiology

Hirotomo Takatsuka, Takumi Higaki, Masaaki Umeda

New
Coupling of bone resorption and formation by RANKL reverse signalling
Biomedical ResearchSet 05 2018Nature

Yuki Ikebuchi, Shigeki Aoki, Masashi Honma, Madoka Hayashi, Yasutaka Sugamori, Masud Khan, Yoshiaki Kariya, Genki Kato, Yasuhiko Tabata, Josef M. Penninger, Nobuyuki Udagawa, Kazuhiro Aoki & Hiroshi Suzuki

New
Cell-to-Cell Heterogeneity in p38-Mediated Cross-Inhibition of JNK Causes Stochastic Cell Death
Cell BiologySet 04 2018Cell Reports

Haruko Miura, Yohei Kondo, Michiyuki Matsuda, Kazuhiro Aoki

New
Super-wide-field two-photon imaging with a micro-optical device moving in post-objective space
NeuroscienceSet 04 2018Nature Communications

Shin-Ichiro Terada, Kenta Kobayashi, Masamichi Ohkura, Junichi Nakai & Masanori Matsuzaki

New
Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior
NeuroscienceAgo 30 2018Neuron

Xinzhu Yu, Anna M.W. Taylor, Jun Nagai, Peyman Golshani, Christopher J. Evans, Giovanni Coppola, Baljit S. Khakh

New
Quantitative Lipid Imaging Reveals a New Signaling Function of Phosphatidylinositol-3,4-Bisphophate: Isoform- and Site-Specific Activation of Akt
Cell BiologyAgo 30 2018Molecular Cell

Shu-Lin Liu, Zhi-Gang Wang, Yusi Hu, Yao Xin, Indira Singaram, Sukhamoy Gorai, Xin Zhou, Yoonjung Shim, Jung-Hyun Min, Liang-Wei Gong, Nissim Hay, Jin Zhang, Wonhwa Cho

New
Thalamocortical Axonal Activity in Motor Cortex Exhibits Layer-Specific Dynamics during Motor Learning
NeuroscienceAgo 30 2018Neuron

Yasuyo H. Tanaka, Yasuhiro R. Tanaka, Masashi Kondo, Shin-Ichiro Terada, Yasuo Kawaguchi, Masanori Matsuzaki

New
14-3-3εa directs the pulsatile transport of basal factors toward the apical domain for lumen growth in tubulogenesis
Developmental BiologyAgo 29 2018PNAS

Yuji Mizotani, Mayu Suzuki, Kohji Hotta, Hidenori Watanabe, Kogiku Shiba, Kazuo Inaba, Etsu Tashiro, Kotaro Oka, and Masaya Imoto

New
SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice
Cell BiologyAgo 28 2018The EMBO Journal

Steven Findlay, John Heath, Vincent M Luo, Abba Malina, Théo Morin, Yan Coulombe, Billel Djerir, Zhigang Li, Arash Samiei, Estelle Simo‐Cheyou, Martin Karam, Halil Bagci, Dolev Rahat, Damien Grapton, Elise G Lavoie, Christian Dove, Husam Khaled, Hellen Kuasne, Koren K Mann, Kathleen Oros Klein, Celia M Greenwood, Yuval Tabach, Morag Park, Jean‐Francois Côté, Jean‐Yves Masson, Alexandre Maréchal, Alexandre Orthwein

New
Muscarinic acetylcholine receptors Chrm1 and Chrm3 are essential for REM sleep
Biomedical ResearchAgo 28 2018Cell Reports

Yasutaka Niwa, Genki N. Kanda, Rikuhiro G. Yamada, Shoi Shi, Genshiro A. Sunagawa, Maki Ukai-Tadenuma, Hiroshi Fujishima, Naomi Matsumoto, Koh-hei Masumoto, Mamoru Nagano, Takeya Kasukawa, James Galloway, Dimitri Perrin, Yasufumi Shigeyoshi, Hideki Ukai, Hiroshi Kiyonari, Kenta Sumiyama, Hiroki R. Ueda

New
Prd1 associates with the clathrin adaptor α-Adaptin and the kinesin-3 Imac/Unc-104 to govern dendrite pruning in Drosophila
NeuroscienceCell BiologyAgo 24 2018PLoS Biology

Wenhui Zong, Yan Wang, Quan Tang, Heng Zhang, Fengwei Yu

New
Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
MicrobiologyAgo 24 2018Nature Communications

Keisuke Nakashima, Satoshi Kimura, Yu Ogawa, Soichi Watanabe, Satoshi Soma, Toyoji Kaneko, Lixy Yamada, Hitoshi Sawada, Che-Huang Tung, Tsai-Ming Lu, Jr-Kai Yu, Alejandro Villar-Briones, Sakura Kikuchi & Noriyuki Satoh 

New
Retinal detachment-induced Müller glial cell swelling activates TRPV4 ion channels and triggers photoreceptor death at body temperature
NeuroscienceAgo 24 2018The Journal of Neuroscience

Hidetaka Matsumoto, Shouta Sugio, François Seghers, David Krizaj, Hideo Akiyama, Yasuki Ishizaki, Philippe Gailly and Koji Shibasaki

New
Investigation of a-Synuclein Amyloid Fibrils Using the Fluorescent Probe Thioflavin T
Biochemistry & Molecular BiologyAgo 23 2018International Journal of Molecular Sciences

Anna I. Sulatskaya, Natalia P. Rodina, Maksim I. Sulatsky, Olga I. Povarova, Iuliia A. Antifeeva, Irina M. Kuznetsova and Konstantin K. Turoverov

New
Efficient Perovskite Solar Cells Fabricated Through CsCl‐Enhanced PbI2 Precursor via Sequential Deposition
Materials ScienceAgo 23 2018Advanced Materials

Qi Li, Yicheng Zhao, Rui Fu, Wenke Zhou, Yao Zhao, Xin Liu, Dapeng Yu, Qing Zhao

New
Monitoring and Updating of Action Selection for Goal-Directed Behavior through the Striatal Direct and Indirect Pathways
NeuroscienceAgo 23 2018Neuron

Satoshi Nonomura, Kayo Nishizawa, Yutaka Sakai, Yasuo Kawaguchi, Shigeki Kato, Motokazu Uchigashima, Masahiko Watanabe, Ko Yamanaka, Kazuki Enomoto, Satomi Chiken, Hiromi Sano, Shogo Soma, Junichi Yoshida, Kazuyuki Samejima, Masaaki Ogawa, Kazuto Kobayashi, Atsushi Nambu, Yoshikazu Isomura, Minoru Kimura

New
Transcriptional switch for programmed cell death in pith parenchyma of sorghum stems
Plant & Animal ScienceAgo 23 2018PNAS

Masaru Fujimoto, Takashi Sazuka, Yoshihisa Oda, Hiroyuki Kawahigashi, Jianzhong Wu, Hideki Takanashi, Takayuki Ohnishi, Jun-ichi Yoneda, Motoyuki Ishimori, Hiromi Kajiya-Kanegae, Ken-ichiro Hibara, Fumiko Ishizuna, Kazuo Ebine, Takashi Ueda, Tsuyoshi Tokunaga, Hiroyoshi Iwata, Takashi Matsumoto, Shigemitsu Kasuga, Jun-ichi Yonemaru, Nobuhiro Tsutsumi

New
Inhibition of MicroRNA-96 Ameliorates Cognitive Impairment and Inactivation Autophagy Following Chronic Cerebral Hypoperfusion in the Rat
Cell BiologyAgo 22 2018Cellular Physiology and BioBiochemistry & Molecular Biology

Liu P., Liu P., Wang Z., Fang S., Liu Y., Wang J., Liu W., Wang N., Chen L., Wang J., Zhang H., Wang L

New
OsPKS1 is required for sexine layer formation, which shows functional conservation between rice and Arabidopsis
Plant & Animal ScienceAgo 22 2018Plant Science

Qiang-Sheng Shi, Kai-Qi Wang, Yue-Ling Li, Lei Zhou, Shuang-Xi Xiong, Yu Han, Yan-Fei Zhang, Nai-Ying Yang, Zhong-Nan Yang, Jun Zhu

New
The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1
Biochemistry & Molecular BiologyAgo 22 2018The Journal of Biological Chemistry

Maria Horiuchi, Takahisa Kuga, Youhei Saito, Maiko Nagano, Jun Adachi, Takeshi Tomonaga, Naoto Yamaguchi, and Yuji Nakayama

New
Chemical Landscape for Tissue Clearing based on Hydrophilic Reagents
BioimagingAgo 21 2018Cell Reports

Kazuki Tainaka, Tatsuya C. Murakami, Etsuo A. Susaki, Chika Shimizu, Rie Saito, Kei Takahashi, Akiko Hayashi-Takagi, Hiroshi Sekiya, Yasunobu Arima, Satoshi Nojima, Masako Ikemura, Tetsuo Ushiku, Yoshihiro Shimizu, Masaaki Murakami, Kenji F. Tanaka, Masamitsu Iino, Haruo Kasai, Toshikuni Sasaoka, Kazuto Kobayashi, Kohei Miyazono, Eiichi Morii, Tadashi Isa, Masashi Fukayama, Akiyoshi Kakita and Hiroki R. Ueda

New
The photosystem II repair cycle requires FtsH turnover through the EngA GTPase
Plant & Animal ScienceAgo 21 2018Plant Physiology

Yusuke Kato, Kiwamu Hyodo, Wataru Sakamoto

New
Deficient humoral responses and disrupted B-cell immunity are associated with fatal SFTSV infection
Cancer & ImmunologyAgo 20 2018Nature Communications

Peixin Song, Nan Zheng, Yong Liu, Chen Tian, Xilin Wu, Xiaohua Ma, Deyan Chen, Xue Zou, Guiyang Wang, Huanru Wang, Yongyang Zhang, Sufang Lu, Chao Wu & Zhiwei Wu

New
Synaptotagmin-associated endoplasmic reticulum-plasma membrane contact sites are localized to immobile ER tubules
Plant & Animal ScienceAgo 20 2018Plant Physiology

Kazuya Ishikawa, Kentaro Tamura, Haruko Ueda, Yoko Ito, Akihiko Nakano, Ikuko Hara-Nishimura, Tomoo Shimada

New
ANGUSTIFOLIA contributes to the regulation of three-dimensional morphogenesis in the liverwort Marchantia polymorpha
Developmental BiologyAgo 20 2018Development

Tomoyuki Furuya, Koro Hattori, Yoshitaka Kimori, Sakiko Ishida, Ryuichi Nishihama, Takayuki Kohchi, Hirokazu Tsukaya

New
Substrate elasticity regulates adipose-derived stromal cell differentiation towards osteogenesis and adipogenesis through β-catenin transduction
Biomedical ResearchAgo 19 2018Acta Biomaterialia

Jing Xie, Demao Zhang, Chenchen Zhou, Quan Yuan, Ling Ye, Xuedong Zhou

New
Pluronic F127 blended polycaprolactone scaffolds via e-jetting for esophageal tissue engineering
Biomedical ResearchAgo 17 2018Journal of Materials Science: Materials in Medicine

Bin Wu, Nobuyoshi Takeshita, Yang Wu, Sanjairaj Vijayavenkataraman, Khek Yu Ho, Wen Feng Lu, Jerry Ying Hsi Fuh

New
Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice
NeuroscienceAgo 16 2018PLoS Genetics

Toru Yoshihara, Hiroyuki Satake, Toshikazu Nishie, Nozomu Okino, Toshihisa Hatta, Hiroki Otani, Chie Naruse, Hiroshi Suzuki, Kazushi Sugihara, Eikichi Kamimura, Noriyo Tokuda, Keiko Furukawa, Koichi Fururkawa, Makoto Ito, Masahide Asano

New
6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway
Cell BiologyAgo 16 2018Autophagy

Yasuomi Urano, Chinatsu Mori, Ayano Fuji, Keito Konno, Takayuki Yamamoto, Shohei Yashirogi, Mayu Ando, Yoshiro Saito & Noriko Noguchi

New
Biased genome editing using the local accumulation of DSB repair molecules system
Biochemistry & Molecular BiologyAgo 16 2018Nature Communications

Shota Nakade, Keiji Mochida, Atsushi Kunii, Kazuki Nakamae, Tomomi Aida, Kohichi Tanaka, Naoaki Sakamoto, Tetsushi Sakuma & Takashi Yamamoto

New
Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning
NeuroscienceAgo 16 2018Neuron

Wataru Kakegawa, Akira Katoh, Sakae Narumi, Eriko Miura, Junko Motohashi, Akiyo Takahashi, Kazuhisa Kohda, Yugo Fukazawa, Michisuke Yuzaki, Shinji Matsuda

New
Identification of 16,25-Odiacetyl-cucurbitane F and 25-O-acetyl-23,24-dihydrocucurbitacin F as novel anti-cancer chemicals
Cancer & ImmunologyBiochemistry & Molecular BiologyAgo 15 2018Royal Society Open Science

Wenxue Wang, Haoran Yang, Ying Li, Zhongfei Zheng, Yongjun Liu, Haiyang Wang, Yanling Mu, Qingqiang Yao

New
Multiple-Condition Analysis in a Retrievable Subcutaneous Animal Model for Drug Screening on Full Pancreatic Tissue Digest
Biomedical ResearchAgo 14 2018ASSAY and Drug Development Technologies

Tim W.G.M. Spitters, Parker L. Andersen, Chloé Martel, and Patrick Vermette

New
The C. elegans BRCA2-ALP/Enigma Complex Regulates Axon Regeneration via a Rho GTPase-ROCK-MLC Phosphorylation Pathway
Cancer & ImmunologyAgo 14 2018Cell Reports

Tatsuhiro Shimizu, Strahil Iv. Pastuhov, Hiroshi Hanafusa, Kunihiro Matsumoto, Naoki Hisamoto

New
Tumor Oxygenation and Hypoxia Inducible Factor-1 Functional Inhibition via a Reactive Oxygen Species Responsive Nanoplatform for Enhancing Radiation Therapy and Abscopal Effects
Biochemistry & Molecular BiologyAgo 13 2018ACS Nano

Lingtong Meng, Yali Cheng, Xiaoning Tong, Shaoju Gan, Yawen Ding, Yu Zhang, Chao Wang, Lei Xu, Yishen Zhu, Jinhui Wu , Yiqiao Hu, and Ahu Yuan

New
Endoribonuclease ENDU-2 regulates multiple traits including cold tolerance via cell autonomous and nonautonomous controls in Caenorhabditis elegans
NeuroscienceAgo 13 2018PNAS

Tomoyo Ujisawa, Akane Ohta, Tatsuya Ii, Yohei Minakuchi, Atsushi Toyoda, Miki Ii, and Atsushi Kuhara

New
Light-induced mechanical response in crosslinked liquid-crystalline polymers with photoswitchable glass transition temperatures
Materials ScienceAgo 13 2018Nature Communications

Youfeng Yue, Yasuo Norikane, Reiko Azumi & Emiko Koyama 

New
Resveratrol-induced p53 activation is associated with autophagy in mouse embryonic stem cells
Stem CellsAgo 08 2018Biochemical and Biophysical Research Communications

Irina I. Suvorova, Aleksandra R. Knyazeva, Valery A. Pospelov

New
Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance
NeuroscienceAgo 07 2018eLife

Kentarou Baba, Wataru Yoshida, Michinori Toriyama, Tadayuki Shimada, Colleen F Manning, Michiko Saito, Kenji Kohno, James S Trimmer, Rikiya Watanabe, Naoyuki Inagaki

New
Protocadherin-mediated cell repulsion controls the central topography and efferent projections of the abducens nucleus
Developmental BiologyAgo 07 2018Cell Reports

Kazuhide Asakawa, Koichi Kawakami

New
Variation in bradyrhizobial NopP effector determines symbiotic incompatibility with Rj2-soybeans via effector-triggered immunity
Plant & Animal ScienceAgo 07 2018Nature Communications

Masayuki Sugawara, Satoko Takahashi, Yosuke Umehara, Hiroya Iwano, Hirohito
Tsurumaru, Haruka Odake, Yuta Suzuki, Hitoshi Kondo, Yuki Konno, Takeo Yamakawa,
Shusei Sato, Hisayuki Mitsui, Kiwamu Minamisawa

New
Pectin RG-I rhamnosyltransferases represent a novel plant-specific glycosyltransferase family
Plant & Animal ScienceAgo 06 2018Nature Plants

Yuto Takenaka, Kohei Kato, Mari Ogawa-Ohnishi, Kana Tsuruhama, Hiroyuki Kajiura, Kenta Yagyu, Atsushi Takeda, Yoichi Takeda, Tadashi Kunieda, Ikuko Hara-Nishimura, Takeshi Kuroha, Kazuhiko Nishitani, Yoshikatsu Matsubayashi & Takeshi Ishimizu 

New
Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
Cancer & ImmunologyAgo 06 2018Nature Communications

Naoki Hisamoto, Anna Tsuge, Strahil Iv. Pastuhov, Tatsuhiro Shimizu, Hiroshi Hanafusa & Kunihiro Matsumoto

New
Bipolar dispersal of red-snow algae
Plant & Animal ScienceAgo 06 2018Nature Communications

Takahiro Segawa, Ryo Matsuzaki, Nozomu Takeuchi, Ayumi Akiyoshi, Francisco Navarro, Shin Sugiyama, Takahiro Yonezawa & Hiroshi Mori 

New
Effects of biphasic and monophasic electrical stimulation on mitochondrial dynamics, cell apoptosis, and cell proliferation
Cell BiologyAgo 04 2018Journal of Cellular Physiology

Maria R. Love, Jirapas Sripetchwandee, Siripong Palee, Siriporn C. Chattipakorn, Morton M. Mower, Nipon Chattipakorn

New
Loss of Fam60a, a Sin3a subunit, results in embryonic lethality and is associated with aberrant methylation at a subset of gene promoters
Developmental BiologyAgo 02 2018eLife

Ryo Nabeshima, Osamu Nishimura, Takako Maeda, Natsumi Shimizu, Takahiro Ide, Kenta Yashiro, Yasuo Sakai, Chikara Meno, Mitsutaka Kadota, Hidetaka Shiratori, Shigehiro Kuraku, Hiroshi Hamada

New
A Rho-based reaction-diffusion system governs cell wall patterning in metaxylem vessels
Plant & Animal ScienceAgo 01 2018Scientific Reports

Yoshinobu Nagashima, Satoru Tsugawa, Atsushi Mochizuki, Takema Sasaki, Hiroo Fukuda & Yoshihisa Oda

New
CD30 characterizes polylobated lymphocytes and disease progression in HTLV-1-infected individuals
Cancer & ImmunologyAgo 01 2018Clinical Cancer Research

Makoto Nakashima, Tadanori Yamochi, Mariko Watanabe, Kaoru Uchimaru, Atae Utsunomiya, Masaaki Higashihara, Toshiki Watanabe and Ryouichi Horie

New
Antineoplastic Actions of Cinnamic Acids and Their Dimers in Breast Cancer Cells: A Comparative Study
Cancer & ImmunologyJul 30 2018Anticancer Research

MEGAN HUNKE, WUILIAN MARTINEZ, AKSHAY KASHYAP, TREYVON BOKOSKIE, MAHESH PATTABIRAMAN and SURABHI CHANDRA

New
Designed peptides that assemble into cross-α amyloid-like structures
Biochemistry & Molecular BiologyJul 30 2018Nature Chemical Biology

Shao-Qing Zhang, Hai Huang, Junjiao Yang, Huong T. Kratochvil, Marco Lolicato, Yanxin Liu, Xiaokun Shu, Lijun Liu & William F. DeGrado

New
Three-dimensional induction of dorsal, intermediate and ventral spinal cord tissues from human pluripotent stem cells
Developmental BiologyJul 30 2018Development

Takenori Ogura, Hideya Sakaguchi, Susumu Miyamoto, Jun Takahashi

New
Differential expression of Lutheran/BCAM regulates biliary tissue remodeling in ductular reaction during liver regeneration
Biomedical ResearchJul 30 2018eLife

Yasushi Miura, Satoshi Matsui, Naoko Miyata, Kenichi Harada, Yamato Kikkawa, Masaki Ohmuraya, Kimi Araki, Shinya Tsurusaki, Hitoshi Okochi, Nobuhito Goda, Atsushi Miyajima, Minoru TanaKa

New
Enhanced water splitting under modal strong coupling conditions
Materials ScienceJul 30 2018Nature Nanotechnology

Xu Shi, Kosei Ueno, Tomoya Oshikiri, Quan Sun, Keiji Sasaki & Hiroaki Misawa

New
Anti-tumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination
Cancer & ImmunologyJul 25 2018Blood

Yasushi Akahori, Linan Wang, Motohiro Yoneyama, Naohiro Seo, Satoshi Okumura, Yoshihiro Miyahara, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, Hiroaki Ikeda, Takehiro Maki, Hiroshi Fujiwara, Yoshiki Akatsuka, Takuma Kato and Hiroshi Shiku

New
Solid-Phase Total Synthesis and Dual Mechanism of Action of the Channel-Forming 48-mer Peptide Polytheonamide B
NeuroscienceJul 24 2018The Journal of the American Chemical Society

Atsushi Hayata, Hiroaki Itoh, Masayuki Inoue

New
Construction of integrated gene logic-chip
Biochemistry & Molecular BiologyJul 23 2018Nature Nanotechnology

Takeya Masubuchi, Masayuki Endo, Ryo Iizuka, Ayaka Iguchi, Dong Hyun Yoon, Tetsushi Sekiguchi, Hao Qi, Ryosuke Iinuma, Yuya Miyazono, Shuichi Shoji, Takashi Funatsu, Hiroshi Sugiyama, Yoshie Harada, Takuya Ueda & Hisashi Tadakuma

New
MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining
Cell BiologyJul 19 2018Molecular Cell

Putzer J. Hung, Britney Johnson, Bo-Ruei Chen, Andrea K. Byrum, Andrea L. Bredemeyer, William T. Yewdell, Tanya E. Johnson, Brian J. Lee, Shruthi Deivasigamani, Issa Hindi, Parmeshwar Amatya, Michael L. Gross, Tanya T. Paull, David J. Pisapia, Jayanta Chaudhuri, John J.H. Petrini, Nima Mosammaparast, Gaya K. Amarasinghe, Shan Zha, Jessica K. Tyler, Barry P. Sleckman

New
Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus
Developmental BiologyJul 19 2018Nature Communications

Keishi Kishimoto, Masaru Tamura, Michiru Nishita, Yasuhiro Minami, Akira Yamaoka, Takaya Abe, Mayo Shigeta & Mitsuru Morimoto

New
Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum
NeuroscienceJul 19 2018Nature Communications

Hisako Nakayama, Manabu Abe, Chie Morimoto, Tadatsune Iida, Shigeo Okabe, Kenji Sakimura & Kouichi Hashimoto

New
SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix
Biomedical ResearchJul 19 2018Nature Communications

Masatoshi Fukuda, Tatsuya Yoshizawa, Md. Fazlul Karim, Shihab U. Sobuz, Wataru Korogi, Daiki Kobayasi, Hiroki Okanishi, Masayoshi Tasaki, Katsuhiko Ono, Tomohiro Sawa, Yoshifumi Sato, Mami Chirifu, Takeshi Masuda, Teruya Nakamura, Hironori Tanoue, Kazuhisa Nakashima, Yoshihiro Kobashigawa, Hiroshi Morioka, Eva Bober, Sumio Ohtsuki, Yuriko Yamagata, Yukio Ando, Yuichi Oike, Norie Araki, Shu Takeda, Hiroshi Mizuta & Kazuya Yamagata

New
Expression profile of the STAND protein Nwd1 in the developing and mature mouse central nervous system
NeuroscienceJul 13 2018Journal of Comparative Neurology

Seiya Yamada  Shin‐ichi Sakakibara

New
Turbulence activates platelet biogenesis to enable clinical scale ex vivo production
Stem CellsJul 12 2018Cell

Yukitaka Ito, Sou Nakamura, Naoshi Sugimoto, Tomohiro Shigemori, Yoshikazu Kato, Mikiko Ohno, Shinya Sakuma, Keitaro Ito, Hiroki Kumon, Hidenori Hirose, Haruki Okamoto, Masayuki Nogawa, Mio Iwasaki, Shunsuke Kihara, Kosuke Fujio, Takuya Matsumoto, Natsumi Higashi, Kazuya Hashimoto, Akira Sawaguchi, Ken-ichi Harimoto, Masato Nakagawa, Takuya Yamamoto, Makoto Handa, Naohide Watanabe, Eiichiro Nishi, Fumihito Arai, Satoshi Nishimura, Koji Eto

New
BMP signaling downstream of the Highwire E3 ligase sensitizes nociceptors
NeuroscienceJul 12 2018PLoS Genetics

Ken Honjo and W. Daniel Tracey

New
Downregulation of splicing regulator RBFOX1 compromises visual depth perception
NeuroscienceJul 12 2018PLOS One

Lei Gu, Dean Bok, Fei Yu, Joseph Caprioli, Natik Piri 

New
Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells
Stem CellsJul 10 2018Stem Cell Reports

Leqian Yu, Junjun Li, Jiayin Hong, Yasuhiro Takashima, Nanae Fujimoto, Minako Nakajima, Akihisa Yamamoto, Xiaofeng Dong, Yujiao Dang, Yu Hou, Wei Yang, Itsunari Minami, Keisuke Okita, Motomu Tanaka, Chunxiong Luo, Fuchou Tang, Yong Chen, Chao Tang, Hidetoshi Kotera, Li Liu

New
Different Roles of Myocardial ROCK1 and ROCK2 in Cardiac Dysfunction and Postcapillary Pulmonary Hypertension in Mice
Biomedical ResearchJul 09 2018PNAS

Shinichiro Sunamura, Kimio Satoh, Ryo Kurosawa, Tomohiro Ohtsuki, Nobuhiro Kikuchi, Md. Elias-Al-Mamun, Toru Shimizu, Shohei Ikeda, Kota Suzuki, Taijyu Satoh, Junichi Omura, Masamichi Nogi, Kazuhiko Numano, Mohammad Abdul Hai Siddique, Satoshi Miyata, Masahito Miura, and Hiroaki Shimokawa

New
A Highly Photostable Near-infrared Labeling Agent Based on a Phospha-rhodamine Enables Long-term and Deep Imaging
Biochemistry & Molecular BiologyJul 08 2018Angewandte Chemie International Edition

Marek Grzybowski, Masayasu Taki, Kieko Senda, Yoshikatsu Sato, Tetsuro Ariyoshi, Yasushi Okada, Ryosuke Kawakami, Takeshi Imamura, and Shigehiro Yamaguchi

New
Cellular localization of the K+‐dependent Na+‐Ca2+ exchanger NCKX5 and the role of the cytoplasmic loop in its distribution in pigmented cells
Cell BiologyJul 07 2018Pigment Cell & Melanoma

Tatiana P. Rogasevskaia, Robert T. Szerencsei, Ali H. Jalloul, Frank Visser, Robert J. Winkfein, Paul P.M. Schnetkamp

New
Status of KRAS in iPSCs Impacts upon Self-Renewal and Differentiation Propensity
Stem CellsJul 05 2018Stem Cell Reports

Kenji Kubara, Kazuto Yamazaki, Yasuharu Ishihara, Takuya Naruto, Huan-Ting Lin, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Masashi Ito, Kappei Tsukahara, Tomohiro Morio, Masatoshi Takagi, Makoto Otsu

New
High-throughput imaging flow cytometry by optofluidic time-stretch microscopy
BioimagingJul 05 2018Nature Protocols

Cheng Lei, Hirofumi Kobayashi, Yi Wu, Ming Li, Akihiro Isozaki, Atsushi Yasumoto, Hideharu Mikami, Takuro Ito, Nao Nitta, Takeaki Sugimura, Makoto Yamada, Yutaka Yatomi, Dino Di Carlo, Yasuyuki Ozeki & Keisuke Goda

New
A Switch-like Activation Relay of EGFR-ERK Signaling Regulates a Wave of Cellular Contractility For Epithelial Invagination
Developmental BiologyJul 05 2018Developmental Cell

Yosuke Ogura, Fu-Lai Wen, Mustafa M. Sami, Tatsuo Shibata, Shigeo Hayashi

New
25‐Hydroxycholesterol protects against acute lung injury via targeting MD‐2
Cancer & ImmunologyJul 05 2018J Cell Mol Med

Wei Ouyang, Hui Zhou, Chao Liu, Shiwei Wang, Yu Han, Jingyan Xia, Feng Xu

New
Lateral Size Scaling Effect during Discontinuous Dewetting
Materials ScienceJul 04 2018Advanced Materials Interfaces

Yinyin Lin, Zhongsheng Wu, Mengying Zhang, Jinbo Wu, Weijia Wen

New
Characterization of Peribiliary Gland–Constituting Cells Based on Differential Expression of Trophoblast Cell Surface Protein 2 (Trop2) in Biliary Tract
Cell BiologyJul 03 2018American Journal of Pathology

Satoshi Matsui, Kenichi Harada, Naoko Miyata, Hitoshi Okochi, Atsushi Miyajima, Minoru Tanaka

New
MTSS1 regulation of actin-nucleating formin DAAM1 in dendritic filopodia determines final dendritic configuration of Purkinje cells
NeuroscienceJul 03 2018Cell Reports

Kelly Kawabata Galbraith, Kazuto Fujishima, Hiroaki Mizuno, Sung-Jin Lee, Takeshi Uemura, Kenji Sakimura, Masayoshi Mishina, Naoki Watanabe, Mineko Kengaku

New
Forebrain Ptf1a is required for sexual differentiation of the brain.
Biomedical ResearchJul 03 2018Cell Reports

Tomoyuki Fujiyama, Satoshi Miyashita, Yousuke Tsuneoka, Kazumasa Kanemaru, Miyo Kakizaki, Satomi Kanno, Yukiko Ishikawa, Mariko Yamashita, Tomoo Owa, Mai Nagaoka, Yoshiya Kawaguchi, Yuchio Yanagawa, Mark A. Magnuson, Masafumi Muratani, Akira Shibuya, Yo-ichi Nabeshima, Masashi Yanagisawa, Hiromasa Funato'Correspondence information about the author Hiromasa Funato, Mikio Hoshino

New
MicroRNA‐19 restores vascular endothelial cell function in lower limb ischemia‐reperfusion injury through the KLF10‐dependent TGF‐β1/Smad signaling pathway in rats
Cell BiologyJun 28 2018Journal of Biological Biochemistry & Molecular Biology

Yong‐Le Xu, Min‐Hong Zhang, Wei Guo, Yan Xue, Xin Du, Tao Zhang, Na Wu, Ye Wu

New
pH sensitive liposomes delivering tariquidar and doxorubicin to overcome multidrug resistance of resistant ovarian cancer cells
PharmacologyCancer & ImmunologyJun 27 2018Colloids and Surfaces B: Biointerfaces

Yuqiong Xia, Mei Fang, Jingyu Dong, Chunzhong Xu, Zhen Liao, Pengbo Ning, Qi Zeng

New
S100B promotes chemoresistance in ovarian cancer stem cells by regulating p53
Cancer & ImmunologyJun 27 2018Oncology Reports

Tao Yang, Jianan Cheng, Junhao You, Bing Yan, Hui Liu, Fang Li

New
RGB-color intensiometric indicators to visualize spatiotemporal dynamics of ATP in single cells
Biochemistry & Molecular BiologyJun 27 2018Angewandte Chemie International Edition

Satoshi Arai, Rókus Kriszt, Kazuki Harada, Liang-Sheng Looi, Shogo Matsuda, Devina Wongso, Satoshi Suo, Shoichi Ishiura, Yu-Hua Tseng, Michael Raghunath, Toshiro Ito, Takashi Tsubo, Tetsuya Kitaguchi

New
A dopaminergic switch for fear to safety transitions
NeuroscienceJun 27 2018Nature Communications

Ray Luo, Akira Uematsu, Adam Weitemier, Luca Aquili, Jenny Koivumaa, Thomas J. McHugh & Joshua P. Johansen

New
Differentiating cells mechanically limit the interkinetic nuclear migration of progenitor cells to secure apical cytogenesis
Developmental BiologyJun 26 2018Development

Yuto Watanabe, Takumi Kawaue, Takaki Miyata

New
Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial Cells
Cancer & ImmunologyJun 26 2018Cell Reports

Hirotaka Watanabe, Kojiro Ishibashi, Hiroki Mano, Sho Kitamoto, Nanami Sato, Kazuya Hoshiba, Mugihiko Kato, Fumihiko Matsuzawa, Yasuto Takeuchi, Takanobu Shirai, Susumu Ishikawa, Yuka Morioka, Toshiaki Imagawa, Kazuyasu Sakaguchi, Suguru Yonezawa, Shunsuke Kon, and Yasuyuki Fujita

New
Formation of arrays of planar, murine, intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone
Biomedical ResearchJun 26 2018Lab on a Chip

Raehyun Kim, Yuli Wang, Shee-Hwan J. Hwang, Peter J. Attayek, Nicole M. Smiddy, Mark I. Reed, Christopher E. Sims and Nancy L. Allbritton

New
An optogenetic approach to control protein localization during embryogenesis of the sea urchin
Developmental BiologyJun 26 2018Developmental Biology

Alicia Uchida, Mamiko Yajima

New
OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses
NeuroscienceJun 25 2018PLoS Genetics

Sayaka Hori, Shigekazu Oda, Yuji Suehiro, Yuichi Iino, Shohei Mitani

New
Ribosomal protein L10A and signaling pathway
Cell BiologyJun 25 2018ScienceDirect

Netnapa Chaichanit, Monwadee Wonglapsuwan, Wilaiwan Chotigeat

New
Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis
Cancer & ImmunologyJun 25 2018Nature Medicine

Peter Savas, Balaji Virassamy, Chengzhong Ye, Agus Salim, Christopher P. Mintoff, Franco Caramia, Roberto Salgado, David J. Byrne, Zhi L. Teo, Sathana Dushyanthen, Ann Byrne, Lironne Wein, Stephen J. Luen, Catherine Poliness, Sophie S. Nightingale, Anita S. Skandarajah, David E. Gyorki, Chantel M. Thornton, Paul A. Beavis, Stephen B. Fox, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab), Phillip K. Darcy, Terence P. Speed, Laura K. Mackay, Paul J. Neeson & Sherene Loi

New
Enhancing Passive Transport of Micro/Nano Particles into Cells by Oxidized Carbon Black
Biochemistry & Molecular BiologyJun 25 2018ACS Omega

Kittima Amornwachirabodee, Supaporn Khramchantuk, Prompong Pienpinijtham, Nipan Israsena, Tanapat Palaga, and Supason Wanichwecharungruang

New
PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy
Cell BiologyJun 22 2018Cell Research

Liming Wang, Yik-Lam Cho, Yancheng Tang, Jigang Wang, Jung-Eun Park, Yajun Wu, Chunxin Wang, Yan Tong, Ritu Chawla, Jianbin Zhang, Yin Shi, Shuo Deng, Guang Lu, Yihua Wu, Hayden Weng-Siong Tan, Pornteera Pawijit, Grace Gui-Yin Lim, Hui-Ying Chan, Jingzi Zhang, Lei Fang, Hanry Yu, Yih-Cherng Liou, Mallilankaraman Karthik, Boon-Huat Bay, Kah-Leong Lim, Siu-Kwan Sze, Celestial T. Yap, and Han-Ming Shen

New
Functional domains of NEAT1 architectural lncRNA induce paraspeckle assembly through phase separation
Cell BiologyJun 21 2018Molecular Cell

Tomohiro Yamazaki, Sylvie Souquere, Takeshi Chujo, Simon Kobelke, Yee Seng Chong, Archa H. Fox, Charles S. Bond, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose

New
Visualizing the Rapid and Dynamic Elimination of Allogeneic T Cells in Secondary Lymphoid Organs
Cancer & ImmunologyJun 20 2018The Journal of Immunology

Yasuhiro Kanda, Arata Takeuchi, Madoka Ozawa, Yoichi Kurosawa, Toshihiko Kawamura, Dana Bogdanova, Hidekazu Iioka, Eisaku Kondo, Yusuke Kitazawa, Hisashi Ueta, Kenjiro Matsuno, Tatsuo Kinashi and Tomoya Katakai

New
The PP2A-like Protein Phosphatase Ppg1 and the Far Complex Cooperatively Counteract CK2-Mediated Phosphorylation of Atg32 to Inhibit Mitophagy
Cell BiologyJun 19 2018Cell Reports

Kentaro Furukawa, Tomoyuki Fukuda, Shun-ichi Yamashita, Tetsu Saigusa, Yusuke Kurihara, Yutaka Yoshida, Hiromi Kirisako, Hitoshi Nakatogawa, and Tomotake Kanki

New
Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment
Cancer & ImmunologyJun 19 2018Clinical Cancer Research

Takuya Kato, Kazuhiro Noma, Toshiaki Ohara, Hajime Kashima, Yuki Katsura, Hiroaki Sato, Satoshi Komoto, Ryoichi Katsube, Takayuki Ninomiya, Hiroshi Tazawa, Yasuhiro Shirakawa and Toshiyoshi Fujiwara

New
MAP1B‐LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules
Cell BiologyJun 19 2018EMBO Reports

Kohei Arasaki, Haruki Nagashima, Yuri Kurosawa, Hana Kimura, Naoki Nishida, Naoshi Dohmae, Akitsugu Yamamoto, Shigeru Yanagi, Yuichi Wakana, Hiroki Inoue, Mitsuo Tagaya

New
Monoamines Inhibit GABAergic Neurons in Ventrolateral Preoptic Area That Make Direct Synaptic Connections to Hypothalamic Arousal Neurons
NeuroscienceJun 18 2018The Journal of Neuroscience

Yuki C. Saito, Takashi Maejima, Mitsuhiro Nishitani, Emi Hasegawa, Yuchio Yanagawa, Michihiro Mieda and Takeshi Sakurai

New
Elimination of melanoma by sortase A-generated TCR-like antibody-drug conjugates (TL-ADCs) targeting intracellular melanoma antigen MART-1
Biomedical ResearchJun 15 2018Biomaterials

Jun Lai, Yun Wang, Shan-Shan Wu, Ding Ding, Ze-Yu Sun, Ying Zhang, Jie Zhou, Zhan Zhou, Ying-Chun Xu, Li-Qiang Pan, Shu-Qing Chen

New
Induction of CD4 T cell memory by local cellular collectivity
Cancer & ImmunologyJun 15 2018Science

Michal Polonsky, Jacob Rimer, Amos Kern-Perets, Irina Zaretsky, Stav Miller, Chamutal Bornstein, Eyal David, Naama Meira Kopelman, Gil Stelzer, Ziv Porat, Benjamin Chain, Nir Friedman

New
DNA methylation mediates BmDeaf1-regulated tissue- and stage-specific expression of BmCHSA-2b in the silkworm, Bombyx mori
Cell BiologyJun 14 2018Epigenetics & Chromatin

Guanfeng Xu, Jie Zhang, Hao Lyu, Qisheng Song, Qili Feng, Hui Xiang and Sichun Zheng

New
A Decrease in the Proliferative Activity of Human Mesenchymal Stem Cells during Long-Term Cultivation is Not Connected with Change in Their Migration Properties
Stem CellsJun 13 2018Cell and Tissue Biology

N. F. Mikheeva, P. A. Butylin, A. Yu. Zaritskii, B. V. Popov 

New
Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder
NeuroscienceJun 11 2018Molecular Psychiatry

Tomoaki M. Kato, Mie Kubota-Sakashita, Noriko Fujimori-Tonou, Fumihito Saitow, Satoshi Fuke, Akira Masuda, Shigeyoshi Itohara, Hidenori Suzuki, Tadafumi Kato

New
20‐hydroxyecdysone‐upregulated proteases involved in Bombyx larval fat body destruction
Biochemistry & Molecular BiologyJun 11 2018Insect Molecular Biology

S.‐Y. Guo, W.‐M. Wu, S.‐Y. Li, Y. Liu, M.‐Q. Ye, Y. Xiao, Y.‐J. Zhong, Y. Cao, K. Li, L. Tian

New
Ulk2 controls cortical excitatory–inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons
NeuroscienceJun 08 2018Human Molecular Genetics

Akiko Sumitomo  Hiroshi Yukitake  Kazuko Hirai  Kouta Horike  Keisho Ueta Youjin Chung  Eiji Warabi  Toru Yanagawa  Shiho Kitaoka  Tomoyuki Furuyashiki Shuh Narumiya  Tomoo Hirano  Minae Niwa  Etienne Sibille  Takatoshi Hikida Takeshi Sakurai  Koko Ishizuka  Akira Sawa  Toshifumi Tomoda

New
Requirement of the 3′-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development
Developmental BiologyJun 08 2018PLoS Genetics

Kurumi Fukuda, Aki Masuda, Takuma Naka, Atsushi Suzuki, Yuzuru Kato, and Yumiko Saga

New
Anti-depressant fluoxetine reveals its therapeutic effect via astrocytes
NeuroscienceJun 08 2018EBioMedicine

Manao Kinoshita, Yuri Hirayama, Kayoko Fujishita, Keisuke Shibata, Youichi Shinozaki, Eiji Shigetomi, Akiko Takeda, Ha Pham Ngoc Le, Hideaki Hayashi, Miki Hiasa, Yoshinori Moriyama, Kazuhiro Ikenaka, Kenji F. Tanaka and Schuichi Koizumi

New
Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine
Biomedical ResearchJun 05 2018Nature Communications

Yu Muta, Yoshihisa Fujita, Kenta Sumiyama, Atsuro Sakurai, M. Mark Taketo, Tsutomu Chiba, Hiroshi Seno, Kazuhiro Aoki, Michiyuki Matsuda, Masamichi Imajo

New
Functional characterization of lysosomal interaction of Akt with VRK2
Developmental BiologyJun 05 2018Oncogene

Noriyuki Hirata, Futoshi Suizu, Mami Matsuda-Lennikov, Tsutomu Tanaka, Tatsuma Edamura, Satoko Ishigaki, Thoria Donia, Pathrapol Lithanatudom, Chikashi Obuse, Toshihiko Iwanaga & Masayuki Noguchi

New
The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis
Biomedical ResearchJun 04 2018Molecular and Cellular Biology

Masatoshi Kobayashi, Mitsuru Ohsugi, Takayoshi Sasako, Motoharu Awazawa, Toshihiro Umehara, Aya Iwane, Naoki Kobayashi, Yukiko Okazaki, Naoto Kubota, Ryo Suzuki, Hironori Waki, Keiko Horiuchi, Takao Hamakubo, Tatsuhiko Kodama, Seiichiro Aoe, Kazuyuki Tobe, Takashi Kadowaki, and Kohjiro Ueki

New
Perineuronal Nets in the Deep Cerebellar Nuclei Regulate GABAergic Transmission and Delay Eyeblink Conditioning
NeuroscienceJun 01 2018The Journal of Neuroscience

Moritoshi Hirono, Satoshi Watanabe, Fuyuki Karube, Fumino Fujiyama, Shigenori Kawahara, Soichi Nagao, Yuchio Yanagawa and Hiroaki Misonou

New
Platelets play an essential role in murine lung development through Clec-2/podoplanin interaction
Cancer & ImmunologyMai 31 2018Blood

Nagaharu Tsukiji Ph.D., Osamu Inoue M.D., Ph.D, Mitsuru Morimoto Ph.D., Norifumi Tatsumi Ph.D., Hiroaki Nagatomo Ph.D., Koji Ueta M.D., Toshiaki Shirai Ph.D., Tomoyuki Sasaki Ph.D., Shimon Otake M.D., Shogo Tamura Ph.D., Toshiaki Tachibana Ph.D, Masataka Okabe M.D., Ph.D, Masanori Hirashima M.D., Ph.D, Yukio Ozaki M.D., Ph.D and Katsue Suzuki-Inoue M.D., Ph.D

New
DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway
Biomedical ResearchMai 31 2018Cell Death & Differentiation

Yoshinobu Saito, Hayato Hikita, Yasutoshi Nozaki, Yugo Kai, Yuki Makino, Tasuku Nakabori, Satoshi Tanaka, Ryoko Yamada, Minoru Shigekawa, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi & Tetsuo Takehara

New
Delivery of mitochondriotropic doxorubicin derivatives using self-assembling hyaluronic acid nanocarriers in doxorubicin-resistant breast cancer
PharmacologyMai 31 2018Acta Pharmacologica Sinica

Hui-na Liu, Ning-ning Guo, Wang-wei Guo, Ming-yi Huang-Fu, Mohammad Reza Vakili, Jie-jian Chen, Wen-hong Xu, Qi-chun Wei, Min Han, Afsaneh Lavasanifar & Jian-qing Gao

New
In vivo reprogramming drives Kras-induced cancer development
Biomedical ResearchMai 25 2018Nature Communications

Hirofumi Shibata, Shingo Komura, Yosuke Yamada, Nao Sankoda, Akito Tanaka, Tomoyo Ukai, Mio Kabata, Satoko Sakurai, Bunya Kuze, Knut Woltjen, Hironori Haga, Yatsuji Ito, Yoshiya Kawaguchi, Takuya Yamamoto & Yasuhiro Yamada

New
Design, Synthesis, and Evaluation of Novel p-(methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G-Quadruplex
Biochemistry & Molecular BiologyMai 25 2018Journal of Medicinal Biochemistry & Molecular Biology

Wang Peng, Zhi-Yin Sun, Qi Zhang, Sui-Qi Cheng, Shi-Ke Wang, Xiao-Na Wang, Guo-Tao Kuang, Xiao-Xuan Su, Jia-Heng Tan, Zhi-Shu Huang, and Tian-Miao Ou

New
Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation
Cell BiologyMai 24 2018Nature Communications

Masaki Tsuchiya, Yuji Hara, Masaki Okuda, Karin Itoh, Ryotaro Nishioka, Akifumi Shiomi, Kohjiro Nagao, Masayuki Mori, Yasuo Mori, Junichi Ikenouchi, Ryo Suzuki, Motomu Tanaka, Tomohiko Ohwada, Junken Aoki, Motoi Kanagawa, Tatsushi Toda, Yosuke Nagata, Ryoichi Matsuda, Yasunori Takayama, Makoto Tominaga & Masato Umeda

New
Arginine-based poly(ester amide) nanoparticle platform: From structure–property relationship to nucleic acid delivery
Biomedical ResearchMai 23 2018Acta Biomaterialia

Xinru You, Zhipeng Gu, Jun Huang, Yang Kang, Chih-Chang Chu, Jun Wu

New
Ischemic brain injury leads to brain edema via hyperthermia-induced TRPV4 activation
NeuroscienceMai 23 2018The Journal of Neuroscience

Yutaka Hoshi, Kohki Okabe, Koji Shibasaki, Takashi Funatsu, Norio Matsuki, Yuji Ikegaya and Ryuta Koyama

New
Recurrent 8q24 rearrangement in blastic plasmacytoid dendritic cell neoplasm: association with immunoblastoid cytomorphology, MYC expression, and drug response
Cancer & ImmunologyMai 23 2018Leukemia

Kana Sakamoto, Ryohei Katayama, Reimi Asaka, Seiji Sakata, Satoko Baba, Hideki Nakasone, Sumie Koike, Naoko Tsuyama, Akito Dobashi, Makoto Sasaki, Ryo Ichinohasama, Emi Takakuwa, Rie Yamazaki, Jun Takizawa, Takahiro Maeda, Miwako Narita, Koji Izutsu, Yoshinobu Kanda, Koichi Ohshima & Kengo Takeuchi

New
Tumor-derived exosomes promote tumor self-seeding in hepatocellular carcinoma by transferring miRNA-25-5p to enhance cell motility
Cancer & ImmunologyMai 22 2018Oncogene

Hao Liu, Wei Chen, Xiao Zhi, En-Jiang Chen, Tao Wei, Jian Zhang, Jian Shen, Li-Qiang Hu, Bin Zhao, Xin-Hua Feng, Xue-Li Bai & Ting-Bo Liang

New
Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17
Cell BiologyMai 22 2018The Journal of Cell Biology

Takahide Matsui, Peidu Jiang, Saori Nakano, Yuriko Sakamaki, Hayashi Yamamoto, Noboru Mizushima

New
Neutrophils Provide a Favorable IL-1-Mediated Immunometabolic Niche that Primes GLUT4 Translocation and Performance in Skeletal Muscles
Cancer & ImmunologyMai 22 2018Cell Reports

Masahiro Tsuchiya, Shigenori Sekiai, Hiroyasu Hatakeyama, Masashi Koide, Chayanit Chaweewannakorn, Fukie Yaoita, Koichi Tan-No, Keiichi Sasaki, Makoto Watanabe, Shunji Sugawara, Yasuo Endo, Eiji Itoi, Yoshihiro Hagiwara, Makoto Kanzaki

New
High-fat Diet-induced Inflammation Accelerates Prostate Cancer Growth via IL6 Signaling
Cancer & ImmunologyMai 18 2018Clinical Cancer Research

Takuji Hayashi, Kazutoshi Fujita, Satoshi Nojima, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Yoshiyuki Yamamoto, Toshiro Kinouchi, Kyosuke Matsuzaki, Kentaro Jingushi, Taigo Kato, Atsunari Kawashima, Akira Nagahara, Takeshi Ujike, Motohide Uemura, Maria Del Carmen Rodriguez Pena, Jennifer B Gordetsky, Eiichi Morii, Kazutake Tsujikawa, George J Netto and Norio Nonomura

New
Phenotypic diversification by enhanced genome restructuring after induction of multiple DNA double-strand breaks
Plant & Animal ScienceMai 18 2018Nature Communications

Nobuhiko Muramoto, Arisa Oda, Hidenori Tanaka, Takahiro Nakamura, Kazuto Kugou, Kazuki Suda, Aki Kobayashi, Shiori Yoneda, Akinori Ikeuchi, Hiroki Sugimoto, Satoshi Kondo, Chikara Ohto, Takehiko Shibata, Norihiro Mitsukawa & Kunihiro Ohta

New
Conclusive Evidence for OCT4 Transcription in Human Cancer Cell Lines: Possible Role of a Small OCT4‐Positive Cancer Cell Population
Stem CellsMai 17 2018Stem Cells

Tomoyuki Miyamoto Nobuhiko Mizuno Mitsuko Kosaka Yoko Fujitani Eiji Ohno Aiji Ohtsuka

New
Conformational Activation of Argonaute by Distinct yet Coordinated Actions of the Hsp70 and Hsp90 Chaperone Systems
Biochemistry & Molecular BiologyMai 17 2018Molecular Cell

Kotaro Tsuboyama, Hisashi Tadakuma'Correspondence information about the author Hisashi TadakumaEmail the author Hisashi Tadakuma, Yukihide Tomari

New
A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells
MicrobiologyMai 17 2018Cell Host & Microbe

Yoichiro Fujioka, Shinya Nishide, Toyoyuki Ose, Tadaki Suzuki, Izumi Kato, Hideo Fukuhara, Mari Fujioka, Kosui Horiuchi, Aya O. Satoh, Prabha Nepal, Sayaka Kashiwagi, Jing Wang, Mika Horiguchi, Yuko Sato, Sarad Paudel, Asuka Nanbo, Tadaaki Miyazaki, Hideki Hasegawa, Katsumi Maenaka, Yusuke Ohba

New
Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease
Cancer & ImmunologyMai 17 2018Nature Communications

Masayoshi Ohkuro, Jun-Dal Kim, Yoshikazu Kuboi, Yuki Hayashi, Hayase Mizukami, Hiroko Kobayashi-Kuramochi, Kenzo Muramoto, Manabu Shirato, Fumiko Michikawa-Tanaka, Jun Moriya, Teruya Kozaki, Kazuma Takase, Kenichi Chiba, Kishan Lal Agarwala, Takayuki Kimura, Makoto Kotake, Tetsuya Kawahara, Naoki Yoneda, Shinsuke Hirota, Hiroshi Azuma, Nobuko Ozasa-Komura, Yoshiaki Ohashi, Masafumi Muratani, Keiji Kimura, Ieharu Hishinuma & Akiyoshi Fukamizu

New
A critical neurodevelopmental role for L-type voltage-gated calcium channels in neurite extension and radial migration
NeuroscienceMai 17 2018The Journal of Neuroscience

Satoshi Kamijo, Yuichiro Ishii, Shin-ichiro Horigane, Kanzo Suzuki, Masamichi Ohkura, Junichi Nakai, Hajime Fujii, Sayaka Takemoto-Kimura and Haruhiko Bito

New
Engineering of vascularized 3D cell constructs to model cellular interactions through a vascular network
Biomedical ResearchMai 16 2018Biomicrofluidics

Emi Sano, Chihiro Mori, Yuji Nashimoto, Ryuji Yokokawa, Hidetoshi Kotera, and Yu-suke Torisawa

New
RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6
Developmental BiologyMai 16 2018Nature

Emmanuelle Szenker-Ravi, Umut Altunoglu, Marc Leushacke, Célia Bosso-Lefèvre, Muznah Khatoo, Hong Thi Tran, Thomas Naert, Rivka Noelanders, Amin Hajamohideen, Claire Beneteau, Sergio B. de Sousa, Birsen Karaman, Xenia Latypova, Seher Başaran, Esra Börklü Yücel, Thong Teck Tan, Lena Vlaeminck, Shalini S. Nayak, Anju Shukla, Katta Mohan Girisha, Cédric Le Caignec, Natalia Soshnikova, Zehra Oya Uyguner, Kris Vleminckx, Nick Barker, Hülya Kayserili, & Bruno Reversade

New
Wolbachia pipientis grows in Saccharomyces cerevisiae evoking early death of the host and deregulation of mitochondrial metabolism
MicrobiologyMai 15 2018MicrobiologyOpen

Cristina Uribe-Alvarez, Natalia Chiquete-Félix, Lilia Morales-García, Arlette Bohórquez-Hernández, Norma Laura Delgado-Buenrostro, Luis Vaca, Antonio Peña, Salvador Uribe-Carvajal

New
Helical rotation of the diaphanous-related formin mDia1 generates actin filaments resistant to cofilin
Cell BiologyMai 14 2018PNAS

Hiroaki Mizuno, Kotaro Tanaka, Sawako Yamashiro, Akihiro Narita, and Naoki Watanabe

New
Two-photon imaging of neuronal activity in motor cortex of marmosets during upper-limb movement tasks
NeuroscienceMai 14 2018Nature Communications

Teppei Ebina, Yoshito Masamizu, Yasuhiro R. Tanaka, Akiya Watakabe, Reiko Hirakawa, Yuka Hirayama, Riichiro Hira, Shin-Ichiro Terada, Daisuke Koketsu, Kazuo Hikosaka, Hiroaki Mizukami, Atsushi Nambu, Erika Sasaki, Tetsuo Yamamori & Masanori Matsuzaki

New
Interleukin-6–mediated trans-signaling inhibits transforming growth factor-β signaling in trabecular meshwork cells
Biochemistry & Molecular BiologyMai 11 2018The Journal of Biological Chemistry

Miyuki Inoue-Mochita, Toshihiro Inoue, Sachi Kojima, Akiko Futakuchi, Tomokazu Fujimoto, Saori Sato-Ohira, Utako Tsutsumi, and Hidenobu Tanihara

New
Integration of two RAB5 groups during endosomal transport in plants
Plant & Animal ScienceMai 11 2018eLife

Emi Ito, Kazuo Ebine, Seung-won Choi, Sakura Ichinose, Tomohiro Uemura, Akihiko Nakano, Takashi Ueda

New
The highly metastatic nature of uterine cervical/endometrial cancer displaying tumor-related leukocytosis: clinical and preclinical investigations
Cancer & ImmunologyMai 11 2018Clinical Cancer Research

Tomoyuki Sasano, Seiji Mabuchi, Katsumi Kozasa, Hiromasa Kuroda, Mahiru Kawano, Ryoko Takahashi, Naoko Komura, Eriko Yokoi, Yuri Matsumoto, Kae Hashimoto, Kenjiro Sawada, Eiichi Morii and Tadashi Kimura

New
Nuclear transport adapts to varying heat stress in a multistep mechanism
Cell BiologyMai 10 2018The Journal of Cell Biology

Yutaka Ogawa, Naoko Imamoto

New
Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation
NeuroscienceMai 09 2018Nature Communications

Nobuko Inoue, Hirofumi Nishizumi, Hiromi Naritsuka, Hiroshi Kiyonari & Hitoshi Sakano

New
Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly
Developmental BiologyMai 09 2018eLife

Hiroshi Yamaguchi, Toshiyuki Oda, Masahide Kikkawa, Hiroyuki Takeda

New
Overlapping function of klf family targets multiple transcription factors to maintain naïve pluripotency of ES cells
Developmental BiologyMai 08 2018Development

Mariko Yamane, Satoshi Ohtsuka, Kumi Matsuura, Akira Nakamura, Hitoshi Niwa

New
Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling
Biochemistry & Molecular BiologyMai 08 2018EMBO Reports

Koji Kikuchi, Akira Nakamura, Masaki Arata, Dongbo Shi, Mami Nakagawa, Tsubasa Tanaka, Tadashi Uemura, Toshihiko Fujimori, Akira Kikuchi, Akiyoshi Uezu, Yasuhisa Sakamoto, Hiroyuki Nakanishi

New
Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the anti-tumor effects of aldehyde dehydrogenase
Cancer & ImmunologyMai 07 2018Cancer Research

Naoya Matsunaga, Takashi Ogino, Yukinori Hara, Takahiro Tanaka, Satoru Koyanagi and Shigehiro Ohdo

New
Trans-2-[4-(dimethylamino)styryl]-3-ethyl-1,3-benzothiazolium perchlorate - New fluorescent dye for testing of amyloid fibrils and study of their structure
Biochemistry & Molecular BiologyMai 04 2018Dyes and Pigments

Anna I. Sulatskaya, Maksim I. Sulatsky, Olga I. Povarova, Natalia P. Rodina, Irina M. Kuznetsova, Alexander A. Lugovskii, Evgeniy S. Voropay, Andrei V. Lavysh, Alexander A. Maskevich, Konstantin K. Turoverov

New
Intra-organ regulation of shade responses
Plant & Animal ScienceMai 04 2018Plant Physiology

Sujung Kim, Nobuyoshi Mochizuki, Ayumi Deguchi, Atsushi J Nagano, Tomomi Suzuki, Akira Nagatani

New
Morphological changes of plasma membrane and protein assembly during clathrin-mediated endocytosis
BioimagingMai 03 2018PLoS Biology

Aiko Yoshida, Nobuaki Sakai, Yoshitsugu Uekusa, Yuka Imaoka, Yoshitsuna Itagaki, Yuki Suzuki, Shige H. Yoshimura

New
Region-specific deletions of the glutamate transporter GLT1 differentially affect nerve injury-induced neuropathic pain in mice
NeuroscienceMai 03 2018Glia

Zhuoyang Zhao  Yuichi Hiraoka  Hiroshi Ogawa  Kohichi Tanaka

New
Glycosylation controls cooperative PECAM-VEGFR2-β3 integrin functions at the endothelial surface for tumor angiogenesis
Cancer & ImmunologyMai 02 2018Oncogene

Rie Imamaki, Kazuko Ogawa, Yasuhiko Kizuka, Yusuke Komi, Soichi Kojima, Norihiro Kotani, Koichi Honke, Takashi Honda, Naoyuki Taniguchi & Shinobu Kitazume

New
Corticospinal circuits from the sensory and motor cortex differentially regulate skilled movements through distinct spinal interneurons.
NeuroscienceMai 01 2018Cell Reports

Masaki Ueno, Yuka Nakamura, Jie Li, Zirong Gu, Jesse Niehaus, Mari Maezawa, Steven A Crone, Martyn Goulding, Mark L Baccei, Yutaka Yoshida

New
Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9
Cell BiologyAbr 30 2018Nucleic Acids Research

Hua Huang, Katannya Kapeli, Wenhao Jin, Yuk Peng Wong, Thiruma Valavan Arumugam, Joanne Huifen Koh, Sumitra Srimasorn, Karthik Mallilankaraman, John Jia En Chua, Gene W. Yeo, and Tuck Wah Soong

New
Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance
NeuroscienceAbr 30 2018Nature Neuroscience

Taka-aki Koshimizu, Kenji Honda, Sachi Nagaoka-Uozumi, Atsuhiko Ichimura, Ikuo Kimura, Michio Nakaya, Nobuya Sakai, Katsushi Shibata, Kentarou Ushijima, Akio Fujimura, Akira Hirasawa, Hitoshi Kurose, Gozoh Tsujimoto, Akito Tanoue & Yukio Takano

New
Green monomeric photosensitizing fluorescent protein for photo-inducible protein inactivation and cell ablation
BioimagingAbr 30 2018BMC Biology

Yemima Dani Riani, Tomoki Matsuda, Kiwamu Takemoto and Takeharu Nagai

New
Uncoordinated centrosome cycle underlies the instability of non-diploid somatic cells in mammals
Cell BiologyAbr 30 2018The Journal of Cell Biology

Kan Yaguchi, Takahiro Yamamoto, Ryo Matsui, Yuki Tsukada, Atsuko Shibanuma, Keiko Kamimura, Toshiaki Koda, Ryota Uehara

New
Synthesis of a selective ratiometric fluorescent probe based on Naphthalimide and its application in human cytochrome P450 1A
Biochemistry & Molecular BiologyAbr 27 2018Talanta

Xiuxuan Zhang, Yan Zhou, Xiaofei Gu, Yu Cheng, Manxin Hong, Liqiang Yan, Fulong Ma, Zhengjian Qi

New
Synthesis of a selective ratiometric fluorescent probe based on Naphthalimide and its application in human cytochrome P450 1A
Biochemistry & Molecular BiologyAbr 27 2018Talanta

Xiuxuan Zhang, Yan Zhou, Xiaofei Gu, Yu Cheng, Manxin Hong, Liqiang Yan, Fulong Ma, Zhengjian Qi

New
Mutations in COA7 cause spinocerebellar ataxia with axonal neuropathy
NeuroscienceAbr 27 2018Brain

Yujiro Higuchi  Ryuta Okunushi  Taichi Hara  Akihiro Hashiguchi  Junhui Yuan Akiko Yoshimura  Kei Murayama  Akira Ohtake  Masahiro Ando  Yu Hiramatsu Satoshi Ishihara  Hajime Tanabe  Yuji Okamoto  Eiji Matsuura  Takehiro Ueda Tatsushi Toda  Sumimasa Yamashita  Kenichiro Yamada  Takashi Koide  Hiroaki Yaguchi Jun Mitsui  Hiroyuki Ishiura  Jun Yoshimura  Koichiro Doi  Shinichi Morishita  Ken Sato Masanori Nakagawa  Masamitsu Yamaguchi  Shoji Tsuji  Hiroshi Takashima

New
Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress
Stem CellsAbr 26 2018Cell Stem Cell

Yuko Tadokoro'Correspondence information about the author Yuko TadokoroEmail the author Yuko Tadokoro, Takayuki Hoshii, Satoshi Yamazaki, Koji Eto, Hideo Ema, Masahiko Kobayashi, Masaya Ueno, Kumiko Ohta, Yuriko Arai, Eiji Hara, Kenichi Harada, Masanobu Oshima, Hiroko Oshima, Fumio Arai, Akihiko Yoshimura, Hiromitsu Nakauchi'Correspondence information about the author Hiromitsu NakauchiEmail the author Hiromitsu Nakauchi, Atsushi Hirao

New
Identification of a neuronal population in the telencephalon essential for fear conditioning in zebrafish
Developmental BiologyAbr 25 2018BMC Biology

Pradeep Lal, Hideyuki Tanabe, Maximiliano L. Suster, Deepak Ailani, Yuri Kotani, Akira Muto, Mari Itoh, Miki Iwasaki, Hironori Wada, Emre Yaksi and Koichi Kawakami

New
Novel Insights into Staphylococcus aureus Deep Bone Infections: the Involvement of Osteocytes
MicrobiologyAbr 24 2018mBio

Dongqing Yang, Asiri R. Wijenayaka, Lucian B. Solomon, Stephen M. Pederson, David M. Findlay, Stephen P. Kidd, Gerald J. Atkins

New
Bioactivity, Safety, and Efficacy of Amphotericin B Nanomicellar Aerosols Using Sodium Deoxycholate Sulfate as the Lipid Carrier
PharmacologyAbr 24 2018AAPS PharmSciTech

Faisal Usman, Ruqaiya Khalil, Zaheer Ul-Haq, Titpawan Nakpheng, and Teerapol Srichana

New
GABAergic local interneurons shape female fruit fly response to mating songs
NeuroscienceAbr 24 2018The Journal of Neuroscience

Daichi Yamada, Hiroshi Ishimoto, Xiaodong Li, Tsunehiko Kohashi, Yuki Ishikawa and Azusa Kamikouchi

New
Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues
Cancer & ImmunologyAbr 24 2018Cell Reports

Ayana Sasaki, Takahiro Nagatake, Riku Egami, Guoqiang Gu, Ichigaku Takigawa, Wataru Ikeda, Tomoya Nakatani, Jun Kunisawa, Yasuyuki Fujita

New
PPi level regulation by H+-PPase & soluble Ppases
Plant & Animal ScienceAbr 24 2018The Plant Cell

Shoji Segami, Takaaki Tomoyama, Shingo Sakamoto, Shizuka Gunji, Mayu Fukuda, Satoru Kinoshita, Nobutaka Mitsuda, Ali Ferjani, Masayoshi Maeshima

New
Bioactivity, Safety, and Efficacy of Amphotericin B Nanomicellar Aerosols Using Sodium Deoxycholate Sulfate as the Lipid Carrier
PharmacologyAbr 24 2018AAPS PharmSciTech

Faisal Usman, Ruqaiya Khalil, Zaheer Ul-Haq, Titpawan Nakpheng, and Teerapol Srichana

New
Novel Insights into Staphylococcus aureus Deep Bone Infections: the Involvement of Osteocytes
MicrobiologyAbr 24 2018mBio

Dongqing Yang, Asiri R. Wijenayaka, Lucian B. Solomon, Stephen M. Pederson, David M. Findlay, Stephen P. Kidd, Gerald J. Atkins

New
Cutting Edge: Identification of Marginal Reticular Cells as Phagocytes of Apoptotic B Cells in Germinal Centers
Cancer & ImmunologyAbr 23 2018The Journal of Immunology

Kazuki Sato, Shin-ichiro Honda, Akira Shibuya and Kazuko Shibuya

New
COBLL1 modulates cell morphology and facilitates androgen receptor genomic binding in advanced prostate cancer
Cancer & ImmunologyAbr 23 2018PNAS

Ken-ichi Takayama, Takashi Suzuki, Tetsuya Fujimura, Satoru Takahashi and Satoshi Inoue

New
WUSCHEL-RELATED HOMEOBOX4 acts as a key regulator in early leaf development in rice
Developmental BiologyAbr 23 2018PLoS Genetics

Yukiko Yasui, Yoshihiro Ohmori, Yumiko Takebayashi, Hitoshi Sakakibara, Hiro-Yuki Hirano

New
Elasticity-based boosting of neuroepithelial nucleokinesis via indirect energy transfer from mother to daughter
Developmental BiologyAbr 20 2018PLoS Biology

Tomoyasu Shinoda, Arata Nagasaka, Yasuhiro Inoue, Ryo Higuchi, Yoshiaki Minami, Kagayaki Kato, Makoto Suzuki, Takefumi Kondo, Takumi Kawaue, Kanako Saito, Naoto Ueno, Yugo Fukazawa, Masaharu Nagayama, Takashi Miura, Taiji Adachi, Takaki Miyata

New
FGF2 Has Distinct Molecular Functions from GDNF in the Mouse Germline Niche
Stem CellsAbr 19 2018Stem Cell Reports

Kaito Masaki, Mizuki Sakai, Shunsuke Kuroki, Jun-Ichiro Jo, Kazuo Hoshina, Yuki Fujimori, Kenji Oka, Toshiyasu Amano, Takahiro Yamanaka, Makoto Tachibana, Yasuhiko Tabata, Tanri Shiozawa, Osamu Ishizuka, Shinichi Hochi, Seiji Takashima

New
The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture
Biochemistry & Molecular BiologyAbr 19 2018The Journal of Biological Chemistry

Chika Takahashi, Koichi Miyatake, Morioh Kusakabe, and Eisuke Nishida

New
Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
Biomedical ResearchAbr 19 2018Nature Communications

Megumi Shiota, Masayuki Naya, Takehiro Yamamoto, Takako Hishiki, Takeharu Tani, Hiroyuki Takahashi, Akiko Kubo, Daisuke Koike, Mai Itoh, Mitsuyo Ohmura, Yasuaki Kabe, Yuki Sugiura, Nobuyoshi Hiraoka, Takayuki Morikawa, Keiyo Takubo, Kentaro Suina, Hideaki Nagashima, Oltea Sampetrean, Osamu Nagano, Hideyuki Saya, Shogo Yamazoe, Hiroyuki Watanabe & Makoto Suematsu

New
A spherical aberration-free microscopy system for live brain imaging
BioimagingAbr 18 2018Biochemical and Biophysical Research Communications

Yoshihiro Ue, Hiromu Monai, Kaori Higuchi, Daisuke Nishiwaki, Tetsuya Tajima, Kenya Okazaki, Hiroshi Hama, Hajime Hirase and Atsushi Miyawaki

New
Extracellular Loop Structures in Silkworm ABCC Transporters Determine their Specificities for Bacillus thuringiensis Cry Toxins
Biochemistry & Molecular BiologyAbr 17 2018The Journal of Biological Chemistry

Haruka Endo, Shiho Tanaka, Satomi Adegawa, Fumika Ichino, Hiroko Tabunoki, Shingo Kikuta, and Ryoichi Sato

New
Jageum-Jung improves 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and suppresses pro-inflammatory chemokine production by inhibiting TNF-α/IFN-γ-induced STAT-1 and NFκB signaling in HaCaT cells
Cancer & ImmunologyAbr 14 2018Journal of Ethnopharmacology

Ju-Hye Yang, Hyun Ju Do, Esther Lee, Nam-Hui Yim, Won-Kyung Cho, Kwang-Il Park, Jin Yeul Ma

New
Jageum-Jung improves 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and suppresses pro-inflammatory chemokine production by inhibiting TNF-α/IFN-γ-induced STAT-1 and NFκB signaling in HaCaT cells
Cancer & ImmunologyAbr 14 2018Journal of Ethnopharmacology

Ju-Hye Yang, Hyun Ju Do, Esther Lee, Nam-Hui Yim, Won-Kyung Cho, Kwang-Il Park, Jin Yeul Ma

New
Micro- and Nano-structured 3D Printed Titanium Implants with Hydroxyapatite Coating for Improved Osseointegration
Biochemistry & Molecular BiologyAbr 13 2018Journal of Materials Chemistry B

Qin Jie, Dongqing Yang, Shaheer Maher, Luis lima-marques, Yanmin Zhou, Yujie Chen, Gerald J Atkins and Dusan Losic

New
A BODIPY disulfonate near-infrared fluorescence-enhanced probe: synthesis, high selectivity to endogenous glutathione and two-photon fluorescent turn-on through thiol-induced SNAr substitution
Biochemistry & Molecular BiologyAbr 13 2018Journal of Materials Chemistry B

Xiang Xia, Ying Qian and Baoxing Shen  

New
A BODIPY disulfonate near-infrared fluorescence-enhanced probe: synthesis, high selectivity to endogenous glutathione and two-photon fluorescent turn-on through thiol-induced SNAr substitution
Biochemistry & Molecular BiologyAbr 13 2018Journal of Materials Biochemistry & Molecular Biology B

Xiang Xia, Ying Qian and Baoxing Shen  

New
Micro- and Nano-structured 3D Printed Titanium Implants with Hydroxyapatite Coating for Improved Osseointegration
Biochemistry & Molecular BiologyAbr 13 2018Journal of Materials Biochemistry & Molecular Biology B

Qin Jie, Dongqing Yang, Shaheer Maher, Luis lima-marques, Yanmin Zhou, Yujie Chen, Gerald J Atkins and Dusan Losic

New
Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury
Stem CellsAbr 12 2018Cell Stem Cell

Aleksandra Tata, Yoshihiko Kobayashi, Ryan D. Chow, Jasmine Tran, Avani Desai, Abdull J. Massri, Timothy J. McCord, Michael Dee Gunn, Purushothama Rao Tata

New
Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury
Stem CellsAbr 12 2018Cell Stem Cell

Aleksandra Tata, Yoshihiko Kobayashi, Ryan D. Chow, Jasmine Tran, Avani Desai, Abdull J. Massri, Timothy J. McCord, Michael Dee Gunn, Purushothama Rao Tata

New
Nucleosomes of polyploid trophoblast giant cells mostly consist of histone variants and form a loose chromatin structure
Cell BiologyAbr 11 2018Scientific Reports

Koji Hayakawa, Kanae Terada, Tomohiro Takahashi, Hidehiro Oana, Masao Washizu, Satoshi Tanaka

New
TGFβ signaling related genes are involved in hormonal mediation during termite soldier differentiation
Plant & Animal ScienceAbr 11 2018PLoS Genetics

Yudai Masuoka, Hajime Yaguchi, Kouhei Toga, Shuji Shigenobu, Kiyoto Maekawa

New
Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs
Stem CellsAbr 11 2018Nature Communications

Takashi Ikeda, Takafusa Hikichi, Hisashi Miura, Hirofumi Shibata, Kanae Mitsunaga, Yosuke Yamada, Knut Woltjen, Kei Miyamoto, Ichiro Hiratani, Yasuhiro Yamada, Akitsu Hotta, Takuya Yamamoto, Keisuke Okita & Shinji Masui

New
Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration
Cell BiologyAbr 11 2018Nature Communications

Akihito Harada, Kazumitsu Maehara, Yusuke Ono, Hiroyuki Taguchi, Kiyoshi Yoshioka, Yasuo Kitajima, Yan Xie, Yuko Sato, Takeshi Iwasaki, Jumpei Nogami, Seiji Okada, Tetsuro Komatsu, Yuichiro Semba, Tatsuya Takemoto, Hiroshi Kimura, Hitoshi Kurumizaka & Yasuyuki Ohkawa

New
SFT-4/Surf4 control ER export of soluble cargo proteins and participate in ER exit site organization
Cell BiologyAbr 11 2018The Journal of Cell Biology

Keiko Saegusa, Miyuki Sato, Nobukatsu Morooka, Taichi Hara, Ken Sato

New
Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling
Cancer & ImmunologyAbr 10 2018Oncotarget

Victoria R. Barnhouse, Jessica L. Weist, Vasudha C. Shukla, Samir N. Ghadiali, Douglas A. Kniss, and Jennifer L. Leight

New
In Vivo Genetic Manipulation of Spermatogonial Stem Cells and Their Microenvironment by Adeno-Associated Viruses
Stem CellsAbr 05 2018Stem Cell Reports

Satoshi Watanabe, Mito Kanatsu-Shinohara, Narumi Ogonuki, Shogo Matoba, Atsuo Ogura, Takashi Shinohara

New
Direct Control of SPEECHLESS by PIF4 in the High-Temperature Response of Stomatal Development
Plant & Animal ScienceAbr 05 2018Current Biology

On Sun Lau, Zhuojun Song, Zimin Zhou, Kelli A. Davies, Jessica Chang, Xin Yang, Shenqi Wang, Doris Lucyshyn, Irene Hui Zhuang Tay, Philip A. Wigge, Dominique C. Bergmann

New
Direct Control of SPEECHLESS by PIF4 in the High-Temperature Response of Stomatal Development
Plant & Animal ScienceAbr 05 2018Current Biology

On Sun Lau, Zhuojun Song, Zimin Zhou, Kelli A. Davies, Jessica Chang, Xin Yang, Shenqi Wang, Doris Lucyshyn, Irene Hui Zhuang Tay, Philip A. Wigge, Dominique C. Bergmann

New
A small peptide modulates stomatal control via abscisic acid in long-distance signalling
Plant & Animal ScienceAbr 04 2018Nature

Fuminori Takahashi, Takehiro Suzuki, Yuriko Osakabe, Shigeyuki Betsuyaku, Yuki Kondo, Naoshi Dohmae, Hiroo Fukuda, Kazuko Yamaguchi-Shinozaki, Kazuo Shinozaki

New
Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D
Cell BiologyAbr 04 2018The Journal of Biological Chemistry

Kou Motani and Hidetaka Kosako

New
Intrahepatic bile ducts guide establishment of the intrahepatic nerve network in developing and regenerating mouse liver
Developmental BiologyAbr 03 2018Development

Naoki Tanimizu, Norihisa Ichinohe, Toshihiro Mitaka

New
Super-long single-molecule tracking reveals dynamic-anchorage-induced integrin function
Biochemistry & Molecular BiologyAbr 02 2018Nature Chemical Biology

Taka A. Tsunoyama, Yusuke Watanabe, Junri Goto, Kazuma Naito, Rinshi S. Kasai, Kenichi G. N. Suzuki, Takahiro K. Fujiwara & Akihiro Kusumi

New
Identification of an Intra- and Inter-specific Tear Protein Signal in Rodents
NeuroscienceMar 29 2018Current Biology

Mai Tsunoda, Kazunari Miyamichi, Ryo Eguchi, Yasuo Sakuma, Yoshihiro Yoshihara, Takefumi Kikusui, Masayoshi Kuwahara, Kazushige Touhara

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
Cancer & ImmunologyDevelopmental BiologyMar 26 2018Developmental Cell

Purushothama Rao Tata, Ryan D. Chow, Srinivas Vinod Saladi, Aleksandra Tata, Arvind Konkimalla, Anne Bara, Daniel Montoro, Lida P. Hariri, Angela R. Shih, Mari Mino-Kenudson, Hongmei Mou, Shioko Kimura, Leif W. Ellisen, Jayaraj Rajagopal

New
Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
Cancer & ImmunologyDevelopmental BiologyMar 26 2018Developmental Cell

Purushothama Rao Tata, Ryan D. Chow, Srinivas Vinod Saladi, Aleksandra Tata, Arvind Konkimalla, Anne Bara, Daniel Montoro, Lida P. Hariri, Angela R. Shih, Mari Mino-Kenudson, Hongmei Mou, Shioko Kimura, Leif W. Ellisen, Jayaraj Rajagopal

High-Throughput Generation of Durable Droplet Arrays for Single-Cell Encapsulation, Culture, and Monitoring
Biochemistry & Molecular BiologyMar 23 2018Analytical Chemistry

Han Wu, Xinlian Chen, Xinghua Gao, Mengying Zhang, Jinbo Wu, and Weijia Wen

New
High-Throughput Generation of Durable Droplet Arrays for Single-Cell Encapsulation, Culture, and Monitoring
Biochemistry & Molecular BiologyMar 23 2018Analytical Biochemistry & Molecular Biology

Han Wu, Xinlian Chen, Xinghua Gao, Mengying Zhang, Jinbo Wu, and Weijia Wen

New
Parathyroid hormone–like hormone induces epithelial-to-mesenchymal transition of intestinal epithelial cells by activating the transcription factor Runx2
Cell BiologyMar 22 2018American Journal of Pathology

Shuying He, Minmin Xue, Cuiping Liu, Fang Xie, Lan Bai 

Parathyroid hormone–like hormone induces epithelial-to-mesenchymal transition of intestinal epithelial cells by activating the transcription factor Runx2
Cell BiologyMar 22 2018American Journal of Pathology

Shuying He, Minmin Xue, Cuiping Liu, Fang Xie, Lan Bai 

New
Species-Specific Mechanisms of Neuron Subtype Specification Reveal Evolutionary Plasticity of Amniote Brain Development
Developmental BiologyMar 20 2018Cell Reports

Tadashi Nomura, Wataru Yamashita, Hitoshi Gotoh, Katsuhiko Ono

New
Aortic carboxypeptidase–like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis
Biomedical ResearchMar 19 2018Journal of Clinical Investigation

Toshiaki Teratani, Kengo Tomita, Takahiro Suzuki, Hirotaka Furuhashi, Rie Irie, Makoto Nishikawa, Junji Yamamoto, Toshifumi Hibi, Soichiro Miura, Tohru Minamino, Yuichi Oike, Ryota Hokari, Takanori Kanai

New
The choroid plexus is an important clock component
NeuroscienceMar 14 2018Nature Communications

Jihwan Myung, Christoph Schmal, Sungho Hong, Yoshiaki Tsukizawa, Pia Rose, Yong Zhang, Michael J Holzman, Erik DeSchutter, Hanspeter Herzel, Grigory Bordyugov, Toru Takumi

New
Excitatory Neuronal Hubs Configure Multisensory Integration of Slow Waves in Association Cortex
NeuroscienceMar 13 2018Cell Reports

Satoshi Kuroki, Takamasa Yoshida, Hidekazu Tsutsui, Mizuho Iwama, Reiko Ando, Takayuki Michikawa, Atsushi Miyawaki, Toshio Ohshima, Shigeyoshi Itohara

New
Simple mechanosense and response of cilia motion reveal the intrinsic habits of ciliates
Biochemistry & Molecular BiologyMar 12 2018PNAS

Takuya Ohmura, Yukinori Nishigami, Atsushi Taniguchi, Shigenori Nonaka, Junichi Manabe, Takuji Ishikawa, Masatoshi Ichikawa

New
The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury
Developmental BiologyMar 09 2018The Journal of Biological Chemistry

Hajime Okada, Minami Yamada, Kenji Kamimoto, Cindy Yuet-Yin Kok, Kota Kaneko, Masatsugu Ema, Atsushi Miyajima, and Tohru Itoh

New
TRPM2 channel aggravates CNS inflammation and cognitive impairment via activation of microglia in chronic cerebral hypoperfusion
NeuroscienceMar 09 2018The Journal of Neuroscience

Jun Miyanohara, Masashi Kakae, Kazuki Nagayasu, Takayuki Nakagawa, Yasuo Mori, Ken Arai, Hisashi Shirakawa and Shuji Kaneko

New
Actin as a cytoskeletal basis for cell architecture and a protein essential for ecdysis in Prorocentrum minimum (Dinophyceae, Prorocentrales)
Cell BiologyMar 08 2018Phycological Research

Mariia Berdieva, Ilya Pozdnyakov, Olga Matantseva, Nikolay Knyazev, Sergei Skarlato

Localization of nectin-2α at the boundary between the adjacent somata of the clustered cholinergic neurons and its regulatory role in the subcellular localization of the voltage-gated A-type K+ channel Kv4.2 in the medial habenula
NeuroscienceMar 08 2018Journal of Comparative Neurology

Hajime Shiotani, Muneaki Miyata, Yu Itoh, Shujie Wang, Aika Kaito, Akira Mizoguchi, Miwako Yamasaki, Masahiko Watanabe, Kenji Mandai, Hideki Mochizuki, and Yoshimi Takai

Actin as a cytoskeletal basis for cell architecture and a protein essential for ecdysis in Prorocentrum minimum (Dinophyceae, Prorocentrales)
Cell BiologyMar 08 2018Phycological Research

Mariia Berdieva, Ilya Pozdnyakov, Olga Matantseva, Nikolay Knyazev, Sergei Skarlato

New
Nesprins and opposing microtubule motors generate a point force that drives directional nuclear motion in migrating neurons
NeuroscienceMar 08 2018Development

You Kure Wu, Hiroki Umeshima, Junko Kurisu, Mineko Kengaku

New
Localization of nectin-2α at the boundary between the adjacent somata of the clustered cholinergic neurons and its regulatory role in the subcellular localization of the voltage-gated A-type K+ channel Kv4.2 in the medial habenula
NeuroscienceMar 08 2018Journal of Comparative Neurology

Hajime Shiotani, Muneaki Miyata, Yu Itoh, Shujie Wang, Aika Kaito, Akira Mizoguchi, Miwako Yamasaki, Masahiko Watanabe, Kenji Mandai, Hideki Mochizuki, and Yoshimi Takai

New
Neuronal Origin of the Temporal Dynamics of Spontaneous BOLD Activity Correlation
NeuroscienceMar 07 2018Cerebral Cortex

Teppei Matsui  Tomonari Murakami  Kenichi Ohki

New
Rab7 knockout unveiled regulated autolysosome maturation induced by glutamine starvation
Cell BiologyMar 07 2018Journal of Cell Science

Yoshihiko Kuchitsu, Yuta Homma, Naonobu Fujita, Mitsunori Fukuda

New
Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis
Cell BiologyMar 06 2018Autophagy

Junji Yamaguchi, Chigure Suzuki, Tomohisa Nanao, Soichirou Kakuta, Kentarou Ozawa, Isei Tanida, Tatsuya Saitoh, Takehiko Sunabori, Masaaki Komatsu, Keiji Tanaka, Shigeki Aoki, Kenji Sakimura & Yasuo Uchiyama

New
B-1a lymphocytes promote oligodendrogenesis during brain development
NeuroscienceMar 05 2018Nature Neuroscience

Shogo Tanabe & Toshihide Yamashita

New
A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing
NeuroscienceMar 05 2018Nature Neuroscience

Tatsuya C. Murakami, Tomoyuki Mano, Shu Saikawa, Shuhei A. Horiguchi, Daichi Shigeta, Kousuke Baba, Hiroshi Sekiya, Yoshihiro Shimizu, Kenji F. Tanaka, Hiroshi Kiyonari, Masamitsu Iino, Hideki Mochizuki, Kazuki Tainaka & Hiroki R. Ueda

New
Single-molecule analysis of phospholipid scrambling by TMEM16F
Biochemistry & Molecular BiologyMar 05 2018PNAS

Rikiya Watanabe, Takaharu Sakuragi, Hiroyuki Noji and Shigekazu Nagata

New
Signaling between pancreatic β-cells and macrophages via S100 calcium-binding protein A8 exacerbates β-cell apoptosis and islet inflammation
Biochemistry & Molecular BiologyMar 01 2018The Journal of Biological Chemistry

Hideaki Inoue, Jun Shirakawa, Yu Togashi, Kazuki Tajima, Tomoko Okuyama, Mayu Kyohara, Yui Tanaka, Kazuki Orime, Yoshifumi Saisho, Taketo Yamada, Kimitaka Shibue, Rohit N. Kulkarni, and Yasuo Terauchi

Secondary Degeneration of Auditory Neurons after Topical Aminoglycoside Administration in a Gerbil Model
NeuroscienceMar 01 2018BioMed Research International

Jae-Hun Lee, Min Young Lee, Phil-Sang Chung, and Jae Yun Jung

Antiviral activity of transiently expressed mitochondrial antiviral signaling adapter, MAVS orthologue from Asian seabass
Cancer & ImmunologyMar 01 2018Fish and Shellfish Immunology

Rahul Krishnan, Jeena K, Zahoor Mushtaq, K.U. Shyam, Pani Prasad Kurcheti

New
Secondary Degeneration of Auditory Neurons after Topical Aminoglycoside Administration in a Gerbil Model
NeuroscienceMar 01 2018BioMed Research International

Jae-Hun Lee, Min Young Lee, Phil-Sang Chung, and Jae Yun Jung

New
Antiviral activity of transiently expressed mitochondrial antiviral signaling adapter, MAVS orthologue from Asian seabass
Cancer & ImmunologyMar 01 2018Fish and Shellfish Immunology

Rahul Krishnan, Jeena K, Zahoor Mushtaq, K.U. Shyam, Pani Prasad Kurcheti

Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations
NeuroscienceFev 28 2018Nature Communications

Gen-ichi Tasaka, Casey J. Guenthner, Amos Shalev, Omri Gilday, Liqun Luo, Adi Mizrahi

New
Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations
NeuroscienceFev 28 2018Nature Communications

Gen-ichi Tasaka, Casey J. Guenthner, Amos Shalev, Omri Gilday, Liqun Luo, Adi Mizrahi

New
Two Parallel Pathways Assign Opposing Odor Valences during Drosophila Memory Formation
Developmental BiologyFev 27 2018Cell Reports

Daisuke Yamazaki, Makoto Hiroi, Takashi Abe, Kazumichi Shimizu, Maki Minami-Ohtsubo, Yuko Maeyama, Junjiro Horiuchi, Tetsuya Tabata

Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin
MicrobiologyCancer & ImmunologyFev 27 2018mBio

Pallab Ghosh, Elizabeth M. Halvorsen, Dustin A. Ammendolia, Nirit Mor-Vaknin, Mary X. D. O’Riordan, John H. Brumell, David M. Markovitz, Darren E. Higgins

New
Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin
MicrobiologyCancer & ImmunologyFev 27 2018mBio

Pallab Ghosh, Elizabeth M. Halvorsen, Dustin A. Ammendolia, Nirit Mor-Vaknin, Mary X. D. O’Riordan, John H. Brumell, David M. Markovitz, Darren E. Higgins
 

New
Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis
NeuroscienceFev 26 2018PNAS

Kouki Abe, Hiroko Katsuno, Michinori Toriyama, Kentarou Baba, Tomoyuki Mori, Toshio Hakoshima, Yonehiro Kanemura, Rikiya Watanabe and Naoyuki Inagaki

T-reg cells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration
Cancer & ImmunologyFev 23 2018PNAS

Marisella Panduro, Christophe Benoist, and Diane Mathis

New
T-reg cells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration
Cancer & ImmunologyFev 23 2018Proceedings of the National Academy of Sciences

Marisella Panduro, Christophe Benoist, and Diane Mathis

New
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p
Cell BiologyFev 22 2018Biochemical and Biophysical Research Communications

Qian Xu, Yazhou Cui, Jing Luan, Xiaoyan Zhou, Haiying Li, Jinxiang Han

New
Mapping the Mouse Cell Atlas by Microwell-Seq
Biomedical ResearchFev 22 2018Cell

Xiaoping Han, Renying Wang, Yincong Zhou, Lijiang Fei, Huiyu Sun, Shujing Lai, Assieh Saadatpour, Zimin Zhou, Haide Chen, Fang Ye, Daosheng Huang, Yang Xu, Wentao Huang, Mengmeng Jiang, Xinyi Jiang, Jie Mao, Yao Chen, Chenyu Lu, Jin Xie, Qun Fang, Yibin Wang, Rui Yue, Tiefeng Li, He Huang, Stuart H. Orkin, Guo-Cheng Yuan, Ming Chen, Guoji Guo

New
EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase
Cancer & ImmunologyFev 22 2018Nature Communications

Kousuke Kasahara, Hiromasa Aoki, Tohru Kiyono, Shujie Wang, Harumi Kagiwada, Mizuki Yuge, Toshio Tanaka, Yuhei Nishimura, Akira Mizoguchi, Naoki Goshima & Masaki Inagaki

New
Single cell bioluminescence imaging of deep tissue in freely moving animals
BioimagingFev 22 2018Science

Satoshi Iwano, Mayu Sugiyama, Hiroshi Hama, Akiya Watakabe, Naomi Hasegawa, Takahiro Kuchimaru, Kazumasa Z. Tanaka, Megumu Takahashi, Yoko Ishida, Junichi Hata, Satoshi Shimozono, Kana Namiki, Takashi Fukano, Masahiro Kiyama, Hideyuki Okano, Shinae Kizaka-Kondoh, Thomas J. McHugh, Tetsuo Yamamori, Hiroyuki Hioki, Shojiro Maki, Atsushi Miyawaki

Mapping the Mouse Cell Atlas by Microwell-Seq
BioimagingFev 22 2018Cell

Xiaoping Han, Renying Wang, Yincong Zhou, Lijiang Fei, Huiyu Sun, Shujing Lai, Assieh Saadatpour, Zimin Zhou, Haide Chen, Fang Ye, Daosheng Huang, Yang Xu, Wentao Huang, Mengmeng Jiang, Xinyi Jiang, Jie Mao, Yao Chen, Chenyu Lu, Jin Xie, Qun Fang, Yibin Wang, Rui Yue, Tiefeng Li, He Huang, Stuart H. Orkin, Guo-Cheng Yuan, Ming Chen, Guoji Guo

Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p
Cell BiologyFev 22 2018Biochemical and Biophysical Research Communications

Qian Xu, Yazhou Cui, Jing Luan, Xiaoyan Zhou, Haiying Li, Jinxiang Han

Spine Patterning Is Guided by Segmentation of the Notochord Sheath
Developmental BiologyFev 20 2018Cell Reports

Wopat S, Bagwell J, Sumigray KD, Dickson AL, Huitema LFA, Poss KD, Schulte-Merker S, Bagnat M

New
Spine Patterning Is Guided by Segmentation of the Notochord Sheath
Developmental BiologyFev 20 2018Cell Reports

Wopat S, Bagwell J, Sumigray KD, Dickson AL, Huitema LFA, Poss KD, Schulte-Merker S, Bagnat M

Neuroprotective effect of Annona glabra extract against ethanol-induced apoptotic neurodegeneration in neonatal rats
NeuroscienceDevelopmental BiologyFev 18 2018Photochemistry and Photobiology, B: Biology

Hongru Ma, Jianfeng Han, Qinchuan Dong

New
Neuroprotective effect of Annona glabra extract against ethanol-induced apoptotic neurodegeneration in neonatal rats
NeuroscienceDevelopmental BiologyFev 18 2018PhotoBiochemistry & Molecular Biology and Photobiology, B: Biology

Hongru Ma, Jianfeng Han, Qinchuan Dong

High-throughput controllable generation of droplet arrays with low consumption
Materials ScienceFev 16 2018Applied Surface Science

Yinyin Lin, Zhongsheng Wu, Yibo Gao, Jinbo Wu, Weijia Wen

New
High-throughput controllable generation of droplet arrays with low consumption
Materials ScienceFev 16 2018Applied Surface Science

Yinyin Lin, Zhongsheng Wu, Yibo Gao, Jinbo Wu, Weijia Wen

New
3′-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells
PharmacologyCancer & ImmunologyFev 15 2018Theranostics

Yan Sun, Yong-Hao Huang, Feng-Ying Huang, Wen-Li Mei, Quan Liu, Cai-Chun Wang, Ying-Ying Lin, Canhua Huang, Yue-Nan Li, Hao-Fu Dai, Guang-Hong Tan

New
Release of Pro-Inflammatory Cytokines from Muscle and Bone Causes Tenocyte Death in a Novel Rotator Cuff In Vitro Explant Culture Model
Biomedical ResearchFev 15 2018Connective Tissue Research

Brianne K. Connizzo and Alan J. Grodzinsky

Release of Pro-Inflammatory Cytokines from Muscle and Bone Causes Tenocyte Death in a Novel Rotator Cuff In Vitro Explant Culture Model
Biomedical ResearchFev 15 2018Connective Tissue Research

Brianne K. Connizzo and Alan J. Grodzinsky

3′-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells
PharmacologyCancer & ImmunologyFev 15 2018Theranostics

Yan Sun, Yong-Hao Huang, Feng-Ying Huang, Wen-Li Mei, Quan Liu, Cai-Chun Wang, Ying-Ying Lin, Canhua Huang, Yue-Nan Li, Hao-Fu Dai, Guang-Hong Tan

New
A NIR rhodamine fluorescent chemodosimeter specific for Glutathione: Knoevenagel Condensation, detection of intracellular Glutathione and living cell imaging
Biochemistry & Molecular BiologyFev 13 2018Journal of Materials Biochemistry & Molecular Biology B

Lu Lu Tong  and   Ying Qian 

New
An evolutionarily conserved NIMA-related kinase directs rhizoid tip growth in the basal land plant Marchantia polymorpha
Developmental BiologyFev 13 2018Development

Kento Otani, Kimitsune Ishizaki, Ryuichi Nishihama, Shogo Takatani, Takayuki Kohchi, Taku Takahashi, Hiroyasu Motose

A NIR rhodamine fluorescent chemodosimeter specific for Glutathione: Knoevenagel Condensation, detection of intracellular Glutathione and living cell imaging
Biochemistry & Molecular BiologyFev 13 2018Journal of Materials Chemistry B

Lu Lu Tong  and   Ying Qian 

New
Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs
Biochemistry & Molecular BiologyFev 12 2018Nature Communications

Tetsutaro Hayashi, Haruka Ozaki, Yohei Sasagawa, Mana Umeda, Hiroki Danno & Itoshi Nikaido

New
Glucocorticoid receptor expression in resident and hematopoietic cells in IgG4-related disease
Biomedical ResearchFev 12 2018Modern Pathology

Taku Iguchi, Koji Takaori, Akiko Mii, Yuki Sato, Yasunori Suzuki, Hajime Yoshifuji, Hiroshi Seno, Osamu Ogawa, Koichi Omori, Kazuhisa Bessho, Satoru Kondo, Tomokazu Yoshizaki, Hitoshi Nakashima, Takao Saito, Tsuneyo Mimori, Hironori Haga, Mitsuhiro Kawano & Motoko Yanagita

New
Lupus-like autoimmune disease caused by a lack of Xkr8, a caspase-dependent phospholipid scramblase
Cancer & ImmunologyFev 12 2018PNAS

Mahiru Kawano and Shigekazu Nagata

New
DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation
Cancer & ImmunologyFev 09 2018Biochemical and Biophysical Research Communications

Takahiro Tomino, Hirotada Tajiri, Takaaki Tatsuguchia, Takahiro Shirai, Kounosuke Oisaki, Shigeki Matsunaga, Fumiyuki Sanematsu, Daiji Sakata, Tomoharu Yoshizumi, Yoshihiko Maehara, Motomu Kanai, Jean-François Cote, Yoshinori Fukui, Takehito Uruno

DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation
Cancer & ImmunologyFev 09 2018Biochemical and Biophysical Research Communications

Takahiro Tomino, Hirotada Tajiri, Takaaki Tatsuguchia,Takahiro Shirai,Kounosuke Oisaki,Shigeki Matsunaga,Fumiyuki Sanematsu,
Daiji Sakata,Tomoharu Yoshizumi, Yoshihiko Maehara,Motomu Kanai,Jean-François Cote,Yoshinori Fukui,Takehito Uruno

New
ADAM8 Is an Antigen of Tyrosine Kinase Inhibitor-Resistant Chronic Myeloid Leukemia Cells Identified by Patient-Derived Induced Pluripotent Stem Cells
Cancer & ImmunologyFev 08 2018Stem Cell Reports

Masashi Miyauchi, Junji Koya, Shunya Arai, Sho Yamazaki, Akira Honda, Keisuke Kataoka, Akihide Yoshimi, Kazuki Taoka, Keiki Kumano, Mineo Kurokawa

New
Hippocampal Ripples Downregulate Synapses
NeuroscienceFev 08 2018Science

Hiroaki Norimoto, Kenichi Makino, Mengxuan Gao, Yu Shikano, Kazuki Okamoto, Tomoe Ishikawa, Takuya Sasaki, Hiroyuki Hioki, Shigeyoshi Fujisawa, Yuji Ikegaya

New
GTL1 and DF1 regulate root hair growth through transcriptional repression of ROOT HAIR DEFECTIVE 6-LIKE 4 in Arabidopsis
Plant & Animal ScienceFev 08 2018Development

Michitaro Shibata, Christian Breuer, Ayako Kawamura, Natalie M. Clark, Bart Rymen, Luke Braidwood, Kengo Morohashi, Wolfgang Busch, Philip N. Benfey, Rosangela Sozzani, Keiko Sugimoto

New
Auditory input shapes tonotopic differentiation of Kv1.1 expression in avian cochlear nucleus during late development
NeuroscienceFev 08 2018The Journal of Neuroscience

Nargis Akter, Ryota Adachi, Akitoshi Kato, Ryota Fukaya and Hiroshi Kuba

New
MYB and MYBL1 in adenoid cystic carcinoma: diversity in the mode of genomic rearrangement and transcripts
Cancer & ImmunologyFev 06 2018Modern Pathology

Yuki Togashi, Akito Dobashi, Seiji Sakata, Yukiko Sato, Satoko Baba, Akira Seto, Hiroki Mitani, Kazuyoshi Kawabata & Kengo Takeuchi

New
Mitochondrial Ferritin is a HIF1a-Inducible Gene that Protects from Hypoxia‐Induced Cell Death in Brain
Biochemistry & Molecular BiologyFev 05 2018Antioxidants and Redox Signaling

Qiong Wu, Wen-Shuang Wu, Lin Su, Xin Zheng, Wenyue Wu, Paolo Santambrogio, Yujing Gou, Qian Hao, Peina Wang, Yaru Li, Bao-Lu Zhao, Guangjun Nie, Sonia Levi, and Yan-Zhong Chang

Mitochondrial Ferritin is a HIF1a-Inducible Gene that Protects from Hypoxia‐Induced Cell Death in Brain
Biochemistry & Molecular BiologyFev 05 2018Antioxidants and Redox Signaling

Qiong Wu, Wen-Shuang Wu, Lin Su, Xin Zheng, Wenyue Wu, Paolo Santambrogio, Yujing Gou, Qian Hao, Peina Wang, Yaru Li, Bao-Lu Zhao, Guangjun Nie, Sonia Levi, and Yan-Zhong Chang

SIP1, a novel SOS2 interaction protein, is involved in salt-stress tolerance in Arabidopsis
Plant & Animal ScienceFev 04 2018Plant Physiology and Biochemistry

Chuntao Wang, Qian Chen, Nan Xiang, Yuanyuan Liu, Xiangxiang Kong, Yongping Yang, Xiangyang Hu

New
SIP1, a novel SOS2 interaction protein, is involved in salt-stress tolerance in Arabidopsis
Plant & Animal ScienceFev 04 2018Plant Physiology and BioBiochemistry & Molecular Biology

Chuntao Wang, Qian Chen, Nan Xiang, Yuanyuan Liu, Xiangxiang Kong, Yongping Yang, Xiangyang Hu

New
Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum
NeuroscienceFev 01 2018Neuron

Naofumi Uesaka, Manabu Abe, Kohtarou Konno, Maya Yamazaki, Kazuto Sakoori, Takaki Watanabe, Tzu-Huei Kao, Takayasu Mikuni, Masahiko Watanabe, Kenji Sakimura and Masanobu Kano

New
Aberrant astrocyte Ca2+ signals “AxCa signals” exacerbate pathological alterations in an alexander disease model
NeuroscienceJan 31 2018Glia

Kozo Saito, Eiji Shigetomi, Rei Yasuda, Ryuichi Sato, Masakazu Nakano, Kei Tashiro, Kenji F. Tanaka, Kazuhiro Ikenaka, Katsuhiko Mikoshiba, Ikuko Mizuta, Tomokatsu Yoshida, Masanori Nakagawa, Toshiki Mizuno and Schuichi Koizumi

New
Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes
Cell BiologyJan 30 2018Journal of Molecular Biology

Gustavo Martínez-Noël, Katja Luck, Simone Kühnle, Alice Desbuleux, Patricia Szajner, Jeffrey T. Galligan, Diana Rodriguez, Leon Zheng, Kathleen Boyland, Flavian Leclere, Quan Zhong, David E. Hill, Marc Vidal, Peter M. Howley

New
M60-like metalloprotease domain of the Escherichia coli YghJ protein forms amyloid fibrils
Cell BiologyJan 30 2018PLOS One

Mikhail V. Belousov, Stanislav A. Bondarev, Anastasiia O. Kosolapova, Kirill S. Antonets, Anna I. Sulatskaya, Maksim I. Sulatsky, Galina A. Zhouravleva, Irina M. Kuznetsova, Konstantin K. Turoverov, Anton A. Nizhnikov

Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes
Cell BiologyJan 30 2018Journal of Molecular Biology

Gustavo Martínez-Noël, Katja Luck, Simone Kühnle, Alice Desbuleux, Patricia Szajner, Jeffrey T. Galligan, Diana Rodriguez, Leon Zheng, Kathleen Boyland, Flavian Leclere, Quan Zhong, David E. Hill, Marc Vidal, Peter M. Howley

M60-like metalloprotease domain of the Escherichia coli YghJ protein forms amyloid fibrils
Cell BiologyJan 30 2018PLOS One

Mikhail V. Belousov, Stanislav A. Bondarev, Anastasiia O. Kosolapova, Kirill S. Antonets, Anna I. Sulatskaya, Maksim I. Sulatsky, Galina A. Zhouravleva, Irina M. Kuznetsova, Konstantin K. Turoverov, Anton A. Nizhnikov

New
Synthetic-Molecule/Protein Hybrid Probe with Fluorogenic Switch for Live-Cell Imaging of DNA Methylation
Biochemistry & Molecular BiologyJan 30 2018Journal of The American Chemical Society

Yuichiro Hori, Norimichi Otomura, Ayuko Nishida, Miyako Nishiura, Maho Umeno, Isao Suetake, and Kazuya Kikuchi

TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer
Cancer & ImmunologyJan 30 2018Oncogene

Ken-ichi Takayama, Takashi Suzuki, Tomoaki Tanaka, Tetsuya Fujimura, Satoru Takahashi, Tomohiko Urano, Kazuhiro Ikeda & Satoshi Inoue

Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology
NeuroscienceJan 30 2018Nature Communications

Kyota Fujita, Xigui Chen, Hidenori Homma, Kazuhiko Tagawa, Mutsuki Amano, Ayumu Saito, Seiya Imoto, Hiroyasu Akatsu, Yoshio Hashizume, Kozo Kaibuchi, Satoru Miyano & Hitoshi Okazawa

erminal Nerve GnRH3 Neurons Mediate Slow Avoidance of Carbon Dioxide in Larval Zebrafish
NeuroscienceJan 29 2018Cell Reports

Tetsuya Koide, Yoichi Yabuki, Yoshihiro Yoshihara

Identification of a Golgi GPI-N-acetylgalactosamine transferase with tandem transmembrane regions in the catalytic domain
Cell BiologyJan 26 2018Nature Communications

Tetsuya Hirata, Sushil K. Mishra, Shota Nakamura, Kazunobu Saito, Daisuke Motooka, Yoko Takada, Noriyuki Kanzawa, Yoshiko Murakami, Yusuke Maeda, Morihisa Fujita, Yoshiki Yamaguchi & Taroh Kinoshita

Generative Cell Specification Requires Transcription Factors Evolutionarily Conserved in Land Plants
Plant & Animal ScienceJan 25 2018Current Biology

Shohei Yamaoka, Ryuichi Nishihama, Yoshihiro Yoshitake, Sakiko Ishida, Keisuke Inoue, Misaki Saito, Keitaro Okahashi, Haonan Bao, Hiroyuki Nishida, Katsushi Yamaguchi, Shuji Shigenobu, Kimitsune Ishizaki, Katsuyuki T. Yamato, Takayuki Kohchi

A Tau-Targeted Multifunctional Nanocomposite for Combinational Therapy of Alzheimer’s Disease
PharmacologyJan 24 2018ACS Nano

Qing Chen, Yang Du, Kai Zhang, Zeyu Liang, Jinquan Li, Hao Yu, Rong Ren, Jin Feng, Zhiming Jin, Fangyuan Li, Jihong Sun, Min Zhou, Qinggang He, Xiaolian Sun, Hong Zhang, Mei Tian, and Daishun Ling

New
A Tau-Targeted Multifunctional Nanocomposite for Combinational Therapy of Alzheimer’s Disease
PharmacologyJan 24 2018ACS Nano

Qing Chen, Yang Du, Kai Zhang, Zeyu Liang, Jinquan Li, Hao Yu, Rong Ren, Jin Feng, Zhiming Jin, Fangyuan Li, Jihong Sun, Min Zhou, Qinggang He, Xiaolian Sun, Hong Zhang, Mei Tian, and Daishun Ling

New
A novel near-infrared styryl-BODIPY fluorescent probe for discrimination of GSH and its application in living cells
Biochemistry & Molecular BiologyJan 23 2018Dyes and Pigments

Chengjun Wang, Xiang Xia, Jirong Luo, Ying Qian

A novel near-infrared styryl-BODIPY fluorescent probe for discrimination of GSH and its application in living cells
Biochemistry & Molecular BiologyJan 23 2018Dyes and Pigments

Chengjun Wang, Xiang Xia, Jirong Luo, Ying Qian

Vesicular nucleotide transporter mediates ATP release and migration in neutrophils
Jan 23 2018The Journal of Biological Chemistry

Yuika Harada, Yuri Kato, Takaaki Miyaji, Hiroshi Omote, Yoshinori Moriyama, and Miki Hiasa

Synapse Elimination Triggered by BMP4 Exocytosis and Presynaptic BMP Receptor Activation
NeuroscienceJan 23 2018Cell Reports

Takahito Higashi, Shinji Tanaka, Tadatsune Iida, Shigeo Okabe

Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease
Cancer & ImmunologyJan 23 2018Blood

Tomohiro Yamakawa, Hiroyuki Ohigashi, Daigo Hashimoto, Eiko Hayase, Shuichiro Takahashi, Miyono Miyazaki, Kenjiro Minomi, Masahiro Onozawa, Yoshiro Niitsu and Takanori Teshima

Induction of porcine reproductive and respiratory syndrome virus (PRRSV)-specific regulatory T lymphocytes (Treg) in the lungs and tracheobronchial lymph nodes of PRRSV-infected pigs
MicrobiologyCancer & ImmunologyJan 22 2018Veterinary Microbiology

Teerawut Nedumpun, Chaitawat Sirisereewan, Chanoknun Thanmuan, Pong Techapongtada, Rinlapas Puntarotairung, Sarun Naraprasertkul, Roongroje Thanawongnuwech, Sanipa Suradhat

New
Induction of porcine reproductive and respiratory syndrome virus (PRRSV)-specific regulatory T lymphocytes (Treg) in the lungs and tracheobronchial lymph nodes of PRRSV-infected pigs
MicrobiologyCancer & ImmunologyJan 22 2018Veterinary Microbiology

Teerawut Nedumpun, Chaitawat Sirisereewan, Chanoknun Thanmuan, Pong Techapongtada, Rinlapas Puntarotairung, Sarun Naraprasertkul, Roongroje Thanawongnuwech, Sanipa Suradhat

New
Control of structure topology and spatial distribution of biomacromolecules in protein ZIF-8 biocomposites
Biochemistry & Molecular BiologyJan 16 2018Biochemistry & Molecular Biology of Materials

Weibin Liang, Raffaele Ricco, Natasha K. Maddigan, Robert P Dickinson, Huoshu Xu, Qiaowei Li, Christopher J. Sumby, Stephen G. Bell, Paolo Falcaro, and Christian J Doonan

Control of structure topology and spatial distribution of biomacromolecules in protein ZIF-8 biocomposites
Biochemistry & Molecular BiologyJan 16 2018Chemistry of Materials

Weibin Liang, Raffaele Ricco, Natasha K. Maddigan, Robert P Dickinson, Huoshu Xu, Qiaowei Li, Christopher J. Sumby, Stephen G. Bell, Paolo Falcaro, and Christian J Doonan

A novel human muscle cell model of Duchenne muscular dystrophy created by CRISPR/Cas9 and evaluation of antisense-mediated exon skipping
PharmacologyJan 16 2018Journal of Human Genetics

Takenori Shimo, Kana Hosoki, Yusuke Nakatsuji, Toshifumi Yokota & Satoshi Obika

New
A novel human muscle cell model of Duchenne muscular dystrophy created by CRISPR/Cas9 and evaluation of antisense-mediated exon skipping
PharmacologyJan 16 2018Journal of Human Genetics

Takenori Shimo, Kana Hosoki, Yusuke Nakatsuji, Toshifumi Yokota & Satoshi Obika

Negative regulation of the Keap1–Nrf2 pathway by a p62/Sqstm1 splicing variant
Cell BiologyJan 16 2018Molecular and Cellular Biology

Shun Kageyama, Tetsuya Saito, Miki Obata, Ryo-hei Koide, Yoshinobu Ichimura, and Masaaki Komatsu

New
TNF-α induces Drp1-mediated mitochondrial fragmentation during inflammatory cardiomyocyte injury
Cell BiologyJan 15 2018International Journal of Molecular Medicine

Yue‑Liang Shen, Ying‑Zhou Shi, Gai‑Ge Chen, Lin‑Lin Wang, Ming‑Zhi Zheng, Hong‑Feng Jin, Ying‑Ying Chen

TNF-α induces Drp1-mediated mitochondrial fragmentation during inflammatory cardiomyocyte injury
Cell BiologyJan 15 2018International Journal of Molecular Medicine

Yue‑Liang Shen, Ying‑Zhou Shi, Gai‑Ge Chen, Lin‑Lin Wang, Ming‑Zhi Zheng, Hong‑Feng Jin, Ying‑Ying Chen

The protein kinase CK2 substrate Jabba modulates lipid metabolism during Drosophila oogenesis
Developmental BiologyJan 11 2018The Journal of Biological Chemistry

Emily A. McMillan, Sheila M. Longo, Michael D. Smith, Sarah Broskin, Baicheng Lin, Nisha K. Singh, and Todd I. Strochlic

New
The protein kinase CK2 substrate Jabba modulates lipid metabolism during Drosophila oogenesis
Developmental BiologyJan 11 2018Journal of Biological Biochemistry & Molecular Biology

Emily A. McMillan, Sheila M. Longo, Michael D. Smith, Sarah Broskin, Baicheng Lin, Nisha K. Singh, and Todd I. Strochlic

New
Nanofiber Membrane supported lung-on-a-chip Microdevice for Anti-cancer Drug Testing
Cancer & ImmunologyBiochemistry & Molecular BiologyJan 09 2018Lab on a Chip

Xingyuan Yang, Kaiyan Li, Xu Zhang, Chang Liu, Bingkun Guo, Weijia Wen, Xinghua Gao

Nanofiber Membrane supported lung-on-a-chip Microdevice for Anti-cancer Drug Testing
Cancer & ImmunologyJan 09 2018Lab on a Chip

Xingyuan Yang, Kaiyan Li, Xu Zhang, Chang Liu, Bingkun Guo, Weijia Wen, Xinghua Gao

Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease
Cell BiologyJan 09 2018Cell Reports

Md Fakruddin, Fan-Yan Wei, Takeo Suzuki, Kana Asano, Takashi Kaieda, Akiko Omori, Ryoma Izumi, Atsushi Fujimura, Taku Kaitsuka, Keishi Miyata, Kimi Araki, Yuichi Oike, Luca Scorrano, Tsutomu Suzuki, Kazuhito Tomizawa

GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose
Biochemistry & Molecular BiologyJan 09 2018Nature Communications

Yusaku Iwasaki, Mio Sendo, Katsuya Dezaki, Tohru Hira, Takehiro Sato, Masanori Nakata, Chayon Goswami, Ryohei Aoki, Takeshi Arai, Parmila Kumari, Masaki Hayakawa, Chiaki Masuda, Takashi Okada, Hiroshi Hara, Daniel J. Drucker, Yuichiro Yamada, Masaaki Tokuda & Toshihiko Yada

Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury
Biomedical ResearchJan 08 2018Nature Medicine

Koshu Okubo, Miho Kurosawa, Mako Kamiya, Yasuteru Urano, Akari Suzuki, Kazuhiko Yamamoto, Koji Hase, Koichiro Homma, Junichi Sasaki, Hiroaki Miyauchi, Tatsuo Hoshino, Matsuhiko Hayashi, Tanya N Mayadas & Junichi Hirahashi

New
An ultrasensitive electrochemical cytosensor based on the magnetic field assisted binanozymes synergistic catalysis of Fe3O4 nanozyme and reduced graphene oxide/molybdenum disulfide nanozyme
Biochemistry & Molecular BiologyJan 07 2018Sensors and Actuators B

Liang Tian, Jinxu Qi, Kun Qian, Olayinka Oderinde, Yingying Cai, Chen Yao, Wei Song, Yihong Wang

Decreased microglial activation through gut-brain axis by prebiotics, probiotics, or synbiotics effectively restored cognitive function in obese-insulin resistant rats
NeuroscienceJan 07 2018Journal of Neuroinflammation

Titikorn Chunchai, Wannipa Thunapong, Sakawdaurn Yasom, Keerati Wanchai, Sathima Eaimworawuthikul, Gabrielle Metzler, Anusorn Lungkaphin, Anchalee Pongchaidecha, Sasithorn Sirilun, Chaiyavat Chaiyasut, Wasana Pratchayasakul, Parameth Thiennimitr, Nipon Chattipakorn, and Siriporn C. Chattipakorn

An ultrasensitive electrochemical cytosensor based on the magnetic field assisted binanozymes synergistic catalysis of Fe3O4 nanozyme and reduced graphene oxide/molybdenum disulfide nanozyme
Biochemistry & Molecular BiologyJan 07 2018Sensors and Actuators B

Liang Tian, Jinxu Qi, Kun Qian, Olayinka Oderinde, Yingying Cai, Chen Yao, Wei Song, Yihong Wang

New
Decreased microglial activation through gut-brain axis by prebiotics, probiotics, or synbiotics effectively restored cognitive function in obese-insulin resistant rats
NeuroscienceJan 07 2018Journal of Neuroinflammation

Titikorn Chunchai, Wannipa Thunapong, Sakawdaurn Yasom, Keerati Wanchai, Sathima Eaimworawuthikul, Gabrielle Metzler, Anusorn Lungkaphin, Anchalee Pongchaidecha, Sasithorn Sirilun, Chaiyavat Chaiyasut, Wasana Pratchayasakul, Parameth Thiennimitr, Nipon Chattipakorn, and Siriporn C. Chattipakorn

Role of Purinergic Receptor P2Y1 in spatiotemporal Ca2+ dynamics in astrocytes
NeuroscienceJan 05 2018The Journal of Neuroscience

Eiji Shigetomi, Yukiho J. Hirayama, Kazuhiro Ikenaka, Kenji F. Tanaka and Schuichi Koizumi

Use of a leukocyte-targeted peptide probe as a potential tracer for imaging the tuberculosis granuloma
MicrobiologyJan 04 2018Tuberculosis

Landon W. Locke, Shankaran Kothandaraman, Michael Tweedle, Sarah Chaney, Daniel J. Wozniak, Larry S. Schlesinger

New
Use of a leukocyte-targeted peptide probe as a potential tracer for imaging the tuberculosis granuloma
MicrobiologyCancer & ImmunologyJan 04 2018Tuberculosis

Landon W. Locke, Shankaran Kothandaraman, Michael Tweedle, Sarah Chaney, Daniel J. Wozniak, Larry S. Schlesinger

Physcomitrella MADS-box genes regulate water supply and sperm movement for fertilization
Plant & Animal ScienceJan 03 2018Nature Plants

Shizuka Koshimizu, Rumiko Kofuji, Yuko Sasaki-Sekimoto, Masahide Kikkawa, Mie Shimojima, Hiroyuki Ohta, Shuji Shigenobu, Yukiko Kabeya, Yuji Hiwatashi, Yosuke Tamada, Takashi Murata & Mitsuyasu Hasebe

Parkinson’s disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking
NeuroscienceJan 03 2018Human Molecular Genetics

Shun Yoshida  Takafumi Hasegawa  Mari Suzuki  Naoto Sugeno Junpei Kobayashi  Morio Ueyama  Mitsunori Fukuda  Akemi Ido-Fujibayashi Kiyotoshi Sekiguchi  Michinori Ezura  Akio Kikuchi  Toru Baba  Atsushi Takeda Hideki Mochizuki  Yoshitaka Nagai  Masashi Aoki

New
PEGylated chitosan nanoparticles with embedded bismuth sulfide for dual-wavelength fluorescent imaging and photothermal therapy
Cancer & ImmunologyBiochemistry & Molecular BiologyJan 02 2018Carbohydrate Polymers

Ke Wang, Jialang Zhuang, Yubing Liu, Maosheng Xu, Jingyuan Zhuang, Zuanguang Chen, Yen Wei, Yuanqing Zhang

PEGylated chitosan nanoparticles with embedded bismuth sulfide for dual-wavelength fluorescent imaging and photothermal therapy
Cancer & ImmunologyJan 02 2018Carbohydrate Polymers

Ke Wang, Jialang Zhuang, Yubing Liu, Maosheng Xu, Jingyuan Zhuang, Zuanguang Chen, Yen Wei, Yuanqing Zhang

Optical silencing of body wall muscles induces pumping inhibition in Caenorhabditis elegans
NeuroscienceDez 27 2017PLoS Genetics

Megumi Takahashi, Shin Takagi

New
Facile Deposition of Manganese Dioxide to Albumin Bound Paclitaxel Nanoparticles for Modulation of Hypoxic Tumor Microenvironment to Improve Chemoradiation Therapy
Cancer & ImmunologyDez 22 2017Molecular Pharmaceutics

Lingtong Meng, Yali Cheng, Shaoju Gan, Zhicheng Zhang, Xiaoning Tong, Lei Xu, Xing Jiang, Yishen Zhu, Jinhui Wu, Ahu Yuan, and Yiqiao Hu

Facile Deposition of Manganese Dioxide to Albumin Bound Paclitaxel Nanoparticles for Modulation of Hypoxic Tumor Microenvironment to Improve Chemoradiation Therapy
Cancer & ImmunologyDez 22 2017Molecular Pharmaceutics

Lingtong Meng, Yali Cheng, Shaoju Gan, Zhicheng Zhang, Xiaoning Tong, Lei Xu, Xing Jiang, Yishen Zhu, Jinhui Wu, Ahu Yuan, and Yiqiao Hu

Revealing chiral cell motility by 3D Riesz transform-differential interference contrast microscopy and computational kinematic analysis
NeuroscienceDez 19 2017Nature Communications

Atsushi Tamada & Michihiro Igarashi

New
Functional characterization of human peptide/histidine transporter 1 in stably transfected MDCK cells
Cell BiologyDez 18 2017Molecular Pharmaceutics

Feifeng Song, Yongjun Hu, Yuqing Wang, David E. Smith, and Huidi Jiang

Functional characterization of human peptide/histidine transporter 1 in stably transfected MDCK cells
Cell BiologyDez 18 2017Molecular Pharmaceutics

Feifeng Song, Yongjun Hu, Yuqing Wang, David E. Smith, and Huidi Jiang

The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans
Cell BiologyDez 18 2017Nature Cell Biology

Miyuki Sato, Katsuya Sato, Kotone Tomura, Hidetaka Kosako & Ken Sato

New
Identification of Cep169-interacting proteins and the in vivo modification sites of Cep169 via proteomic analysis
Cell BiologyDez 17 2017Biochemical and Biophysical Research Communications

Miyuki Shintomi, Mikihiro Shiratori, Lumi Negishi, Yasuhiko Terada

Identification of Cep169-interacting proteins and the in vivo modification sites of Cep169 via proteomic analysis
Cell BiologyDez 17 2017Biochemical and Biophysical Research Communications

Miyuki Shintomi, Mikihiro Shiratori, Lumi Negishi, Yasuhiko Terada

APUM24 and nucleolar stress
Plant & Animal ScienceDez 14 2017The Plant Cell

Shugo Maekawa, Tetsuya Ishida, Shuichi Yanagisawa

APP upregulation contributes to retinal ganglion cell degeneration via JNK3
NeuroscienceDez 13 2017Cell Death & Differentiation

Chao Liu, Cheng-Wu Zhang, Yi Zhou, Wan Qing Wong, Liying Corinne Lee, Wei Yi Ong, Sung Ok Yoon, Wanjin Hong, Xin-Yuan Fu, Tuck Wah Soong, Edward H. Koo, Lawrence W. Stanton, Kah-Leong Lim, Zhi-Cheng Xiao, Gavin S. Dawe

New
APP upregulation contributes to retinal ganglion cell degeneration via JNK3
NeuroscienceDez 13 2017Cell Death & Differentiation

Chao Liu, Cheng-Wu Zhang, Yi Zhou, Wan Qing Wong, Liying Corinne Lee, Wei Yi Ong, Sung Ok Yoon, Wanjin Hong, Xin-Yuan Fu, Tuck Wah Soong, Edward H. Koo, Lawrence W. Stanton, Kah-Leong Lim, Zhi-Cheng Xiao, Gavin S. Dawe

CCL28-Deficient Mice Have Reduced IgA Antibody–Secreting Cells and an Altered Microbiota in the Colon
Cancer & ImmunologyDez 13 2017The Journal of Immunology

Kazuhiko Matsuo, Daisuke Nagakubo, Shinya Yamamoto, Akiko Shigeta, Shuta Tomida, Mitsugu Fujita, Takako Hirata, Ikuo Tsunoda, Takashi Nakayama and Osamu Yoshie

Synaptic weight set by Munc13-1 supramolecular assemblies
NeuroscienceDez 11 2017Nature Neuroscience

Hirokazu Sakamoto, Tetsuroh Ariyoshi, Naoya Kimpara, Kohtaroh Sugao, Isamu Taiko, Kenji Takikawa, Daisuke Asanuma, Shigeyuki Namiki & Kenzo Hirose

Salt-inducible kinase 3 regulates the mammalian circadian clock by destabilizing PER2 protein
NeuroscienceDez 11 2017eLife

Naoto Hayasaka Arisa Hirano Yuka Miyoshi Isao T Tokuda Hikari Yoshitane Junichiro Matsuda Yoshitaka Fukada

New
Copper (II) oxide nanozyme based electrochemical cytosensor for high sensitive detection of circulating tumor cells in breast cancer
Cancer & ImmunologyDez 08 2017Journal of Electroanalytical Biochemistry & Molecular Biology

Liang Tian, Jinxu Qi, Kun Qian, Olayinka Oderinde, Qinyao Liu, Chen Yao, Wei Song, Yihong Wang

Copper (II) oxide nanozyme based electrochemical cytosensor for high sensitive detection of circulating tumor cells in breast cancer
Cancer & ImmunologyDez 08 2017Journal of Electroanalytical Chemistry

Liang Tian, Jinxu Qi, Kun Qian, Olayinka Oderinde, Qinyao Liu, Chen Yao, Wei Song, Yihong Wang

N-Glycan–dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing
Cell BiologyDez 08 2017The Journal of Cell Biology

Yi-Shi Liu, Xin-Yu Guo, Tetsuya Hirata, Yao Rong, Daisuke Motooka, Toshihiko Kitajima, Yoshiko Murakami, Xiao-Dong Gao, Shota Nakamura, Taroh Kinoshita, Morihisa Fujita

Mechanosensory-Based Phase Coding of Odor Identity in the Olfactory Bulb
NeuroscienceDez 06 2017Neuron

Ryo Iwata, Hiroshi Kiyonari, Takeshi Imai

Identification of genes regulating GABAergic interneuron maturation
NeuroscienceNov 30 2017Neuroscience Research

Keita Fukumoto, Kota Tamada, Tsuyoshi Toya, Tasuku Nishino, Yuchio Yanagawa, Toru Takumi

New
Identification of genes regulating GABAergic interneuron maturation
NeuroscienceNov 30 2017Neuroscience Research

Keita Fukumoto, Kota Tamada, Tsuyoshi Toya, Tasuku Nishino, Yuchio Yanagawa, Toru Takumi

Divergent Connectivity of Homologous Command-like Neurons Mediates Segment-Specific Touch Responses in Drosophila
NeuroscienceNov 30 2017Neuron

Suguru Takagi, Benjamin Thomas Cocanougher, Sawako Niki, Dohjin Miyamoto, Hiroshi Kohsaka, Hokto Kazama, Richard Doty Fetter, James William Truman, Marta Zlatic, Albert Cardona, Akinao Nose

Distinct roles for plasma membrane PtdIns(4)P and PtdIns(4,5)P2 during receptor-mediated endocytosis in yeast
Cell BiologyNov 30 2017Journal of Cell Science

Wataru Yamamoto, Suguru Wada, Makoto Nagano, Kaito Aoshima, Daria Elisabeth Siekhaus, Junko Y. Toshima, Jiro Toshima

TRPV4 heats up ANO1-dependent exocrine gland fluid secretion
Cell BiologyNov 29 2017The FASEB Journal

Sandra Derouiche, Yasunori Takayama, Masataka Murakami, and Makoto Tominaga

Lipopolysaccharide structure impacts the entry kinetics of bacterial outer membrane vesicles into host cells
Cancer & ImmunologyNov 29 2017PLOS Pathogens

O'Donoghue EJ, Sirisaengtaksin N, Browning DF, Bielska E, Hadis M, Fernandez-Trillo F, Alderwick L, Jabbari S, Krachler AM.

New
Lipopolysaccharide structure impacts the entry kinetics of bacterial outer membrane vesicles into host cells
Cancer & ImmunologyNov 29 2017PLoS Pathogens

O'Donoghue EJ, Sirisaengtaksin N, Browning DF, Bielska E, Hadis M, Fernandez-Trillo F, Alderwick L, Jabbari S, Krachler AM.

CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations
NeuroscienceNov 28 2017eLife

Mihara Shigeki Ohta Kimiko Fukuda Kenji Kurosawa Wado Akamatsu Tsukasa Sanosaka Jun Kohyama Kanehiro Hayashi Kazunori Nakajima Takao Takahashi Joanna Wysocka Kenjiro Kosaki Hideyuki Okano

A Highly Sensitive FRET Biosensor for AMPK Exhibits Heterogeneous AMPK Responses among Cells and Organs
Cell BiologyNov 28 2017Cell Reports

Yumi Konagaya, Kenta Terai, Yusuke Hirao, Kanako Takakura, Masamichi Imajo, Yuji Kamioka, Norio Sasaoka, Akira Kakizuka, Kenta Sumiyama, Tomoichiro Asano, Michiyuki Matsuda

An asymmetric attraction model for the diversity and robustness of cell arrangement in nematodes
Developmental BiologyNov 28 2017Development

Kazunori Yamamoto, Akatsuki Kimura

New
A critical role for dopamine D5 receptors in pain chronicity in male mice
NeuroscienceNov 22 2017Jneurosci

Salim Megat, Stephanie Shiers, Jamie K. Moy, Paulino Barragan-Iglesias, Grishma Pradhan, Rebecca P. Seal, Gregory Dussor and Theodore J. Price

New
MMP-2 Sensitive HA end-conjugated poly(amidoamine) dendrimers via click reaction to enhance drug penetration into solid tumor
Cancer & ImmunologyNov 21 2017Applied Materials & Interfaces

Min Han, Ming-Yi Huang-Fu, Wang-Wei Guo, Ningning Guo, Jiejian Chen, Huina Liu, Zhiqi Xie, Mengting Lin, Qichun Wei, and Jianqing Gao

MMP-2 Sensitive HA end-conjugated poly(amidoamine) dendrimers via click reaction to enhance drug penetration into solid tumor
Cancer & ImmunologyNov 21 2017Applied Materials & Interfaces

Min Han, Ming-Yi Huang-Fu, Wang-Wei Guo, Ningning Guo, Jiejian Chen, Huina Liu, Zhiqi Xie, Mengting Lin, Qichun Wei, and Jianqing Gao

RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation
NeuroscienceNov 21 2017eLife

Kei Nakayama Rie Ohashi Yo Shinoda Maya Yamazaki Manabu Abe Akihiro Fujikawa Shuji Shigenobu Akira Futatsugi Masaharu Noda Katsuhiko Mikoshiba Teiichi Furuichi Kenji Sakimura Nobuyuki Shiina

Structural basis for the assembly of the Ragulator-Rag GTPase complex
Biochemistry & Molecular BiologyNov 21 2017Nature Communications

Ryo Yonehara, Shigeyuki Nada, Tomokazu Nakai, Masahiro Nakai, Ayaka Kitamura, Akira Ogawa, Hirokazu Nakatsumi, Keiichi I. Nakayama, Songling Li, Daron M. Standley, Eiki Yamashita, Atsushi Nakagawa & Masato Okada

Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
Biochemistry & Molecular BiologyNov 21 2017Nature Communications

Hirotake Miyauchi, Satomi Moriyama, Tsukasa Kusakizako, Kaoru Kumazaki, Takanori Nakane, Keitaro Yamashita, Kunio Hirata, Naoshi Dohmae, Tomohiro Nishizawa, Koichi Ito, Takaaki Miyaji, Yoshinori Moriyama, Ryuichiro Ishitani & Osamu Nureki

New
A Mediated BOD Biosensor Based on Immobilized B. Subtilis on Three-Dimensional Porous Graphene-Polypyrrole Composite
Biomedical ResearchNov 20 2017Sensors

Jingfang Hu, Yueqi Li, Guowei Gao, and Shanhong Xia

A Mediated BOD Biosensor Based on Immobilized B. Subtilis on Three-Dimensional Porous Graphene-Polypyrrole Composite
BioimagingNov 20 2017Sensors

Jingfang Hu, Yueqi Li, Guowei Gao, and Shanhong Xia

Both Nodal signalling and stochasticity select for prospective distal visceral endoderm in mouse embryos
Developmental BiologyNov 14 2017Nature Communications

Katsuyoshi Takaoka, Hiromi Nishimura & Hiroshi Hamada

Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells
Cancer & ImmunologyNov 14 2017Cell Reports

Kayama, Shushi Nagamori, Pornparn Kongpracha, Eiji Umemoto, Ryu Okumura, Takashi Kurakawa, Mari Murakami, Norihisa Mikami, Yasunori Shintani, Satoko Ueno, Ayatoshi Andou, Morihiro Ito, Hideki Tsumura, Koji Yasutomo, Keiichi Ozono, Seiji Takashima, Shimon Sakaguchi, Yoshikatsu Kanai, Kiyoshi Takeda

SATB1 Conditional Knockout Results in Sjögren’s Syndrome in Mice
Cancer & ImmunologyNov 10 2017The Journal of Immunology

Yuriko Tanaka, Takehiko Sotome, Akiko Inoue, Takanori Mukozu, Taku Kuwabara, Tetuo Mikami, Terumi Kowhi-Shigematsu and Motonari Kondo

Higher-Order Kidney Organogenesis from Pluripotent Stem Cells
Stem CellsNov 09 2017Cell Stem Cell

Atsuhiro Taguchi, Ryuichi Nishinakamura

Intracellular Protein-Labeling Probes for Multicolor Single-Molecule Imaging of Immune Receptor–Adaptor Molecular Dynamics
Biochemistry & Molecular BiologyNov 09 2017Journal of The American Chemical Society

Ryota Sato, Jun Kozuka, Masahiro Ueda, Reiko Mishima, Yutaro Kumagai, Akimasa Yoshimura, Masafumi Minoshima, Shin Mizukami, and Kazuya Kikuchi

Distinct Laterality in Forelimb-Movement Representations of Rat Primary and Secondary Motor Cortical Neurons with Intratelencephalic and Pyramidal Tract Projections
NeuroscienceNov 08 2017The Journal of Neuroscience

Shogo Soma, Akiko Saiki, Junichi Yoshida, Alain Ríos, Masanori Kawabata, Yutaka Sakai and Yoshikazu Isomura

Propagating Wave of ERK Activation Orients Collective Cell Migration
Developmental BiologyNov 06 2017Developmental Cell

Kazuhiro Aoki, Yohei Kondo, Honda Naoki, Toru Hiratsuka, Reina E. Itoh, Michiyuki Matsuda

Area-specific regulation of quiescent neural stem cells by Notch3 in the adult mouse subependymal zone
NeuroscienceStem CellsNov 03 2017The Journal of Neuroscience

Hiroki Kawai, Daichi Kawaguchi, Benjamin D. Kuebrich, Takeo Kitamoto, Masahiro Yamaguchi, Yukiko Gotoh and Shohei Furutachi

New
Area-specific regulation of quiescent neural stem cells by Notch3 in the adult mouse subependymal zone
NeuroscienceStem CellsNov 03 2017Jneurosci

Hiroki Kawai, Daichi Kawaguchi, Benjamin D. Kuebrich, Takeo Kitamoto, Masahiro Yamaguchi, Yukiko Gotoh and Shohei Furutachi

CORTICAL MICROTUBULE DISORDERING1 Is Required for Secondary Cell Wall Patterning in Xylem Vessels
Plant & Animal ScienceNov 03 2017The Plant Cell

Takema Sasaki, Hiroo Fukuda, Yoshihisa Oda

Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen
Cancer & ImmunologyNov 03 2017The Journal of Immunology

Yasuhiro Mouri, Yoshihiro Ueda, Tomoyoshi Yamano, Minoru Matsumoto, Koichi Tsuneyama, Tatsuo Kinashi and Mitsuru Matsumoto

New
TRPV4 heats up ANO1-dependent exocrine gland fluid secretion
Cell BiologyNov 02 2017FASEB Journal

Sandra Derouiche, Yasunori Takayama, Masataka Murakami, and Makoto Tominaga

New
Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle
Cell BiologyNov 02 2017Molecular Cell

Asako Sakaue-Sawano, Masahiro Yo, Naoki Komatsu, Toru Hiratsuka, Takako Kogure, Tetsushi Hoshida, Naoki Goshima, Michiyuki Matsuda, Hiroyuki Miyoshi, and Atsushi Miyawaki

New
Nonsteroidal Anti-Inflammatory Drug-Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells
Biochemistry & Molecular BiologyNov 02 2017ACS Infectious Diseases

Aadra P. Bhatt, Dulan B. Gunasekara, Jennifer Speer, Mark I. Reed, Alexis N. Peña, Bentley R. Midkiff, Scott T. Magness, Scott J. Bultman, Nancy L. Allbritton, and Matthew R. Redinbo

Nonsteroidal Anti-Inflammatory Drug-Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells
Biochemistry & Molecular BiologyNov 02 2017ACS Infectious Diseases

Aadra P. Bhatt, Dulan B. Gunasekara, Jennifer Speer, Mark I. Reed, Alexis N. Peña, Bentley R. Midkiff, Scott T. Magness, Scott J. Bultman, Nancy L. Allbritton, and Matthew R. Redinbo

Osteoblast Production by Reserved Progenitor Cells in Zebrafish Bone Regeneration and Maintenance
Developmental BiologyNov 02 2017Developmental Cell

Kazunori Ando, Eri Shibata, Stefan Hans, Michael Brand, Atsushi Kawakami

Kinetics of Releasable Synaptic Vesicles and Their Plastic Changes at Hippocampal Mossy Fiber Synapses
NeuroscienceNov 02 2017Neuron

Mitsuharu Midorikawa, Takeshi Sakaba

Rufy3 is an adapter protein for small GTPases that activates a Rac guanine nucleotide exchange factor to control neuronal polarity
NeuroscienceOut 31 2017The Journal of Biological Chemistry

Atsuko Honda, Hiroshi Usui, Kenji Sakimura, and Michihiro Igarashi

Genetically-Encoded Tools for Optical Dissection of the Mammalian Cell Cycle
Biochemistry & Molecular BiologyOut 26 2017Molecular Cell

Asako Sakaue-Sawano, Masahiro Yo, Naoki Komatsu, Toru Hiratsuka, Takako Kogure, Tetsushi Hoshida, Naoki Goshima, Michiyuki Matsuda, Hiroyuki Miyoshi, and Atsushi Miyawaki

R-Spondin1 expands Paneth cells and prevents dysbiosis induced by graft-versus-host disease
Cancer & ImmunologyOut 24 2017The Journal of Experimental Medicine

Eiko Hayase, Daigo Hashimoto, Kiminori Nakamura, Clara Noizat, Reiki Ogasawara, Shuichiro Takahashi, Hiroyuki Ohigashi, Yuki Yokoi, Rina Sugimoto, Satomi Matsuoka, Takahide Ara, Emi Yokoyama, Tomohiro Yamakawa, Ko Ebata, Takeshi Kondo, Rina Hiramine, Tomoyasu Aizawa, Yoshitoshi Ogura, Tetsuya Hayashi, Hiroshi Mori, Ken Kurokawa, Kazuma Tomizuka, Tokiyoshi Ayabe, Takanori Teshima

Motor neurons with limb-innervating character in the cervical spinal cord are sculpted by apoptosis based on the Hox code in chick embryo
Developmental BiologyOut 23 2017Development

Motor neurons with limb-innervating character in the cervical spinal cord are sculpted by apoptosis based on the Hox code in chick embryo

Autophagy induction under carbon starvation conditions is negatively regulated by carbon catabolite repression
Cell BiologyOut 17 2017The Journal of Biological Chemistry

Atsuhiro Adachi, Michiko Koizumi, and Yoshinori Ohsumi

Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway
Cell BiologyOut 16 2017PNAS

Takamasa Mizoguchi, Shoko Ikeda, Saori Watanabe, Michiko Sugawara, and Motoyuki Itoh

Small conductance Ca2+-activated K+ channels induce the firing pause periods during the activation of Drosophila nociceptive neurons
NeuroscienceOut 16 2017eLife

Koun Onodera Shumpei Baba Akira Murakami Tadashi Uemura Tadao Usui

A long-range cis-regulatory element for class I odorant receptor genes
NeuroscienceOut 12 2017Nature Communications

Tetsuo Iwata, Yoshihito Niimura, Chizuru Kobayashi, Daichi Shirakawa, Hikoyu Suzuki, Takayuki Enomoto, Kazushige Touhara, Yoshihiro Yoshihara & Junji Hirota

An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling
Developmental BiologyOut 11 2017Gene & Development

Yoshika Hayakawa-Yano, Satoshi Suyama, Masahiro Nogami, Masato Yugami, Ikuko Koya, Takako Furukawa, Li Zhou, Manabu Abe, Kenji Sakimura, Hirohide Takebayashi, Atsushi Nakanishi, Hideyuki Okano, and Masato Yano

New
Triple functions nanocomposites of porous silica-CoFe2O4-MWCNTs as carrier for pH-sensitive anti-cancer drugs controlled delivery
Cancer & ImmunologyOut 10 2017Dalton Transactions

Bo Li, Hui-Tao Fan, Xiaojing Xing, Yuhan Yang, Cong-Cong Wang and Dong-Fang Qiu

Triple functions nanocomposites of porous silica-CoFe2O4-MWCNTs as carrier for pH-sensitive anti-cancer drugs controlled delivery
Cancer & ImmunologyOut 10 2017Dalton Transactions

Bo Li, Hui-Tao Fan, Xiaojing Xing, Yuhan Yang, Cong-Cong Wang and Dong-Fang Qiu  

New
Skin penetration and UV-damage prevention by nanoberries
Cell BiologyOut 09 2017Journal of Cosmetic Dermatology

Paula Bucci,Maria Jimena Prieto, Laura Milla, Maria Natalia Calienni, Luis Martinez, Viviana Rivarola, Silvia Alonso, Jorge Montanari

Skin penetration and UV-damage prevention by nanoberries
Cell BiologyOut 09 2017Journal of Cosmetic Dermatology

Paula Bucci,Maria Jimena Prieto, Laura Milla, Maria Natalia Calienni, Luis Martinez, Viviana Rivarola, Silvia Alonso, Jorge Montanari

The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age
Stem CellsOut 06 2017Nature Communications

Kentaro Hosokawa, Ben D. MacArthur, Yoshiko Matsumoto Ikushima, Hirofumi Toyama, Yoshikazu Masuhiro, Shigemasa Hanazawa, Toshio Suda & Fumio Arai

New
3-sulfo-galactosyl dependent adhesion of Escherichia coli HS Multivalent Adhesion Molecule is attenuated by sulfatase activity
Cell BiologyOut 05 2017Journal of Biological Biochemistry & Molecular Biology

Fitua Al-Saedi, Diana Pereira Vaz, Daniel H Stones, Anne Marie Krachler

3-sulfo-galactosyl dependent adhesion of Escherichia coli HS Multivalent Adhesion Molecule is attenuated by sulfatase activity
Cell BiologyOut 05 2017The Journal of Biological Chemistry

Fitua Al-Saedi, Diana Pereira Vaz, Daniel H Stones, Anne Marie Krachler

Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells
Stem CellsOut 05 2017Cell Stem Cell

Yoji Kojima, Kotaro Sasaki, Shihori Yokobayashi, Yoshitake Sakai, Tomonori Nakamura, Yukihiro Yabuta, Fumio Nakaki, So Nagaoka, Knut Woltjen, Akitsu Hotta, Takuya Yamamoto, Mitinori Saitou

Cytoplasmic MTOCs control spindle orientation for asymmetric cell division in plants
Cell BiologyOut 02 2017PNAS

Ken Kosetsu, Takashi Murata, Moé Yamada, Momoko Nishina, Joanna Boruc, Mitsuyasu Hasebe, Daniël Van Damme, and Gohta Goshima

Functional Segregation and Development of Mouse Higher Visual Areas
NeuroscienceSet 27 2017The Journal of Neuroscience

Tomonari Murakami, Teppei Matsui and Kenichi Ohki

Nuclear movement regulated by non-Smad Nodal signaling via JNK is associated with Smad signaling during zebrafish endoderm specification
Developmental BiologySet 25 2017Development

Shunya Hozumi, Shun Aoki, Yutaka Kikuchi

Optogenetic Activation of the Sensorimotor Cortex Reveals “Local Inhibitory and Global Excitatory” Inputs to the Basal Ganglia
NeuroscienceSet 25 2017eLife

Masashi Kondo Kenta Kobayashi Masamichi Ohkura Junichi Nakai Masanori Matsuzaki

Optogenetic Activation of the Sensorimotor Cortex Reveals “Local Inhibitory and Global Excitatory” Inputs to the Basal Ganglia
NeuroscienceSet 25 2017Cerebral Cortex

Mitsunori Ozaki  Hiromi Sano  Shigeki Sato  Mitsuhiro Ogura Hajime Mushiake  Satomi Chiken  Naoyuki Nakao  Atsushi Nambu

Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage
Plant & Animal ScienceSet 21 2017Nature Communications

Poyu Chen, Hirotomo Takatsuka, Naoki Takahashi, Rie Kurata, Yoichiro Fukao, Kosuke Kobayashi, Masaki Ito & Masaaki Umeda

Bone morphogenetic protein and retinoic acid synergistically specify female germ‐cell fate in mice
Biochemistry & Molecular BiologySet 19 2017The EMBO Journal

Hidetaka Miyauchi, Hiroshi Ohta, So Nagaoka, Fumio Nakaki, Kotaro Sasaki, Katsuhiko Hayashi, Yukihiro Yabuta, Tomonori Nakamura, Takuya Yamamoto, Mitinori Saitou

Dnmt1-dependent Chk1 pathway suppression is protective against neuron division
Developmental BiologySet 19 2017Development

Mio Oshikawa, Kei Okada, Hidenori Tabata, Koh-ichi Nagata, Itsuki Ajioka

Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis
Biomedical ResearchSet 11 2017Journal of Clinical Investigation

Naoto Koyanagi, Takahiko Imai, Keiko Shindo, Ayuko Sato, Wataru Fujii, Takeshi Ichinohe, Naoki Takemura, Shigeru Kakuta, Satoshi Uematsu, Hiroshi Kiyono, Yuhei Maruzuru, Jun Arii, Akihisa Kato, Yasushi Kawaguchi

Difference in Dachsous Levels between Migrating Cells Coordinates the Direction of Collective Cell Migration
Developmental BiologySet 11 2017Developmental Cell

Masaki Arata, Kaoru Sugimura, Tadashi Uemura

Rapid transporter regulation prevents substrate flow traffic jams in boron transport
Plant & Animal ScienceSet 05 2017eLife

Naoyuki Sotta Susan Duncan Mayuki Tanaka Takafumi Sato Athanasius FM Marée Toru Fujiwara  Verônica A Grieneisen

New
Expression of periostin in breast cancer cells
Cancer & ImmunologyAgo 30 2017International Journal of Oncology

Katarzyna Ratajczak-Wielgomas, Jedrzej Grzegrzolka, Aleksandra Piotrowska, Rafal Matkowski, Andrzej Wojnar, Janusz Rys, Maciej Ugorski, Piotr Dziegiel

Heterogeneity of mesenchymal and pluripotent stem cell populations grown on nanogrooves and nanopillars
Stem CellsAgo 30 2017Journal of Materials Chemistry B

Peng-Yuan Wang, Sheryl Ding, Raymond Wong, Peter Kingshott

Expression of periostin in breast cancer cells
Cancer & ImmunologyAgo 30 2017International Journal of Oncology

Katarzyna Ratajczak-Wielgomas, Jedrzej Grzegrzolka, Aleksandra Piotrowska, Rafal Matkowski, Andrzej Wojnar, Janusz Rys, Maciej Ugorski, Piotr Dziegiel

New
Heterogeneity of mesenchymal and pluripotent stem cell populations grown on nanogrooves and nanopillars
Stem CellsAgo 30 2017Journal of Materials Biochemistry & Molecular Biology B

Peng-Yuan Wang, Sheryl Ding, Raymond Wong, Peter Kingshott

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model
Stem CellsAgo 30 2017Nature

Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Hiroaki Magotani, Hirotaka Onoe, Takuya Hayashi, Hiroshi Mizuma, Sayuki Takara, Ryosuke Takahashi, Haruhisa Inoue, Satoshi Morita, Michio Yamamoto, Keisuke Okita, Masato Nakagawa, Malin Parmar & Jun Takahash

Polo-like kinase Cdc5 regulates Spc72 recruitment to spindle pole body in the methylotrophic yeast Ogataea polymorpha
Biochemistry & Molecular BiologyAgo 30 2017eLife

Hiromi Maekawa Annett Neuner Diana Rüthnick Elmar Schiebel Gislene Pereira Yoshinobu Kaneko

In vitro Generation of Mouse Colon Crypts
Stem CellsAgo 29 2017ASC Biomaterials Science & Engineering

Yuli Wang, Dulan Gunasekara, Peter Attayek, Mark Reed, Matthew DiSalvo, Daniel Luke Nguyen, Johanna Dutton, Michael S. Lebhar, Scott Bultman, Christopher E Sims, Scott Magness, and Nancy L Allbritton

New
In vitro Generation of Mouse Colon Crypts
Stem CellsAgo 29 2017ASC Biomaterials Science & Engineering

Yuli Wang, Dulan Gunasekara, Peter Attayek, Mark Reed, Matthew DiSalvo, Daniel Luke Nguyen, Johanna Dutton, Michael S. Lebhar, Scott Bultman, Christopher E Sims, Scott Magness, and Nancy L Allbritton

Rab35 GTPase recruits NDP52 to autophagy targets
Biochemistry & Molecular BiologyAgo 28 2017The EMBO Journal

Atsuko Minowa‐Nozawa, Takashi Nozawa, Keiko Okamoto‐Furuta, Haruyasu Kohda, Ichiro Nakagawa

Evidence for ESCRT- and clathrin-dependent microautophagy
Cell BiologyAgo 24 2017The Journal of Cell Biology

Masahide Oku, Yuichiro Maeda, Yoko Kagohashi, Takeshi Kondo, Mai Yamada, Toyoshi Fujimoto, Yasuyoshi Sakai

Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development
Biomedical ResearchAgo 21 2017PNAS

Yasuhiro Umemura, Nobuya Koike, Munehiro Ohashi, Yoshiki Tsuchiya, Qing Jun Meng, Yoichi Minami, Masayuki Hara, Moe Hisatomi, and Kazuhiro Yagita

Differing contributions of the first and second pharyngeal arches to tympanic membrane formation in the mouse and chick
Developmental BiologyAgo 21 2017Development

Toshiko Furutera, Masaki Takechi, Taro Kitazawa, Junko Takei, Takahiko Yamada, Tri Vu Hoang, Filippo M. Rijli, Hiroki Kurihara, Shigeru Kuratani, Sachiko Iseki

Development of fertile mouse oocytes from mitotic germ cells in vitro
Developmental BiologyAgo 10 2017Nature Protocols

Kanako Morohaku, Yuji Hirao & Yayoi Obata

Neural Circuitry that Evokes Escape Behavior upon Activation of Nociceptive Sensory Neurons in Drosophila Larvae
NeuroscienceAgo 10 2017Current Biology

Jiro Yoshino, Rei K. Morikawa, Eri Hasegawa, Kazuo Emoto

A Novel Plasma Membrane-Anchored Protein Regulates Xylem Cell-Wall Deposition through Microtubule-Dependent Lateral Inhibition of Rho GTPase Domains
Plant & Animal ScienceAgo 10 2017Current Biology

Yuki Sugiyama, Mayumi Wakazaki, Kiminori Toyooka, Hiroo Fukuda, Yoshihisa Oda

Retrograde BDNF to TrkB signaling promotes synapse elimination in the developing cerebellum
NeuroscienceAgo 04 2017Nature Communications

Myeongjeong Choo, Taisuke Miyazaki, Maya Yamazaki, Meiko Kawamura, Takanobu Nakazawa, Jianling Zhang, Asami Tanimura, Naofumi Uesaka, Masahiko Watanabe, Kenji Sakimura & Masanobu Kano

C/EBPβ is required for survival of Ly6C− monocytes
Cancer & ImmunologyAgo 04 2017Blood

Akihiro Tamura, Hideyo Hirai, Asumi Yokota, Naoka Kamio, Atsushi Sato, Tsukimi Shoji, Takahiro Kashiwagi, Yusuke Torikoshi, Yasuo Miura, Daniel G. Tenen and Taira Maekawa

Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis
Cancer & ImmunologyAgo 02 2017PNAS

Yuichi Yanagihashi, Katsumori Segawa, Ryota Maeda, Yo-ichi Nabeshima, and Shigekazu Nagata

The Arabidopsis LAZY1 Family Plays a Key Role in Gravity Signaling within Statocytes and in Branch Angle Control of Roots and Shoots
Plant & Animal ScienceAgo 01 2017The Plant Cell

Masatoshi Taniguchi, Masahiko Furutani, Takeshi Nishimura, Moritaka Nakamura, Toyohito Fushita, Kohta Iijima, Kenichiro Baba, Hirokazu Tanaka, Masatsugu Toyota, Masao Tasaka, Miyo Terao Morita

Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly
Cell BiologyAgo 01 2017eLife

Atsuko Shirai Takayuki Kawaguchi Hideaki Shimojo Daisuke Muramatsu Mayumi Ishida-Yonetani Yoshifumi Nishimura Hiroshi Kimura Jun-ichi Nakayama Yoichi Shinkai

Nrp2 is sufficient to instruct circuit formation of mitral-cells to mediate odour-induced attractive social responses
NeuroscienceJul 21 2017Nature Communications

Kasumi Inokuchi, Fumiaki Imamura, Haruki Takeuchi, Ryang Kim, Hiroyuki Okuno, Hirofumi Nishizumi, Haruhiko Bito, Takefumi Kikusui & Hitoshi Sakano

Origins of Cell-Type-Specific Olfactory Processing in the Drosophila Mushroom Body Circuit
NeuroscienceJul 19 2017Neuron

Kengo Inada, Yoshiko Tsuchimoto, Hokto Kazama

High expression of ABCG2 induced by EZH2 disruption has pivotal roles in MDS pathogenesis
Cancer & ImmunologyJul 19 2017Leukemia

K C Kawabata, Y Hayashi, D Inoue, H Meguro, H Sakurai, T Fukuyama, Y Tanaka, S Asada, T Fukushima, R Nagase, R Takeda, Y Harada, J Kitaura, S Goyama, H Harada, H Aburatani & T Kitamura

TH2A is phosphorylated at meiotic centromere by Haspin
Reproductive BiologyJul 17 2017Chromosoma

Masashi Hada, Jihye Kim, Erina Inoue, Yuko Fukuda, Hiromitsu Tanaka, Yoshinori Watanabe, Yuki Okada

New
TH2A is phosphorylated at meiotic centromere by Haspin
Reproductive BiologyJul 17 2017Chromosoma

Masashi Hada, Jihye Kim, Erina Inoue, Yuko Fukuda, Hiromitsu Tanaka, Yoshinori Watanabe, Yuki Okada

Dynamic Organization of Chromatin Domains Revealed by Super-Resolution Live-Cell Imaging
Biochemistry & Molecular BiologyJul 13 2017Molecular Cell

Tadasu Nozaki, Ryosuke Imai, Mai Tanbo, Ryosuke Nagashima, Sachiko Tamura, Tomomi Tani, Yasumasa Joti, Masaru Tomita, Kayo Hibino, Masato T. Kanemaki, Kerstin S. Wendt, Yasushi Okada, Takeharu Nagai, Kazuhiro Maeshima

Type XVII collagen coordinates proliferation in the interfollicular epidermis
Biomedical ResearchJul 11 2017eLife

Mika Watanabe Ken Natsuga Wataru Nishie Yasuaki Kobayashi Giacomo Donati Shotaro Suzuki Yu Fujimura Tadasuke Tsukiyama Hideyuki Ujiie Satoru Shinkuma Hideki Nakamura Masamoto Murakami Michitaka Ozaki Masaharu Nagayama Fiona M Watt Hiroshi Shimizu

Defects in dosage compensation impact global gene regulation in the mouse trophoblast
Developmental BiologyJul 06 2017Development

Yuka Sakata, Koji Nagao, Yuko Hoki, Hiroyuki Sasaki, Chikashi Obuse, Takashi Sado

Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution
Cancer & ImmunologyJul 05 2017Cell Reports

Shimpei I. Kubota, Kei Takahashi, Jun Nishida, Yasuyuki Morishita, Shogo Ehata, Kazuki Tainaka, Kohei Miyazono, Hiroki R. Ueda

New
Simvastatin induced actin cytoskeleton disassembly in normal and transformed fibroblasts without affecting lipid raft integrity
Cell BiologyJul 03 2017Cell Biology International

Vladislav I. Chubinskiy-Nadezhdin, Yuri A. Negulyaev, and Elena A. Morachevskaya

Simvastatin induced actin cytoskeleton disassembly in normal and transformed fibroblasts without affecting lipid raft integrity
Cell BiologyJul 03 2017Cell Biology International

Vladislav I. Chubinskiy-Nadezhdin, Yuri A. Negulyaev, and Elena A. Morachevskaya

Glutamate transporter GLAST controls synaptic wrapping by Bergmann glia and ensures proper wiring of Purkinje cells
NeuroscienceJun 27 2017PNAS

Taisuke Miyazaki, Miwako Yamasaki, Kouichi Hashimoto, Kazuhisa Kohda, Michisuke Yuzaki, Keiko Shimamoto, Kohichi Tanaka, Masanobu Kano, and Masahiko Watanabe

DNA cytoskeleton for stabilizing artificial cells
Biochemistry & Molecular BiologyJun 26 2017PNAS

Chikako Kurokawa, Kei Fujiwara, Masamune Morita, Ibuki Kawamata, Yui Kawagishi, Atsushi Sakai, Yoshihiro Murayama, Shin-ichiro M. Nomura, Satoshi Murata, Masahiro Takinoue, and Miho Yanagisawa

Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca2+ permeable AMPA receptor-system xc
NeuroscienceJun 23 2017Toxicology in Vitro

Xin-yue Wang, Yan-li Li, Hai-yun Wang, Min Zhu, Di Guo, Guo-lin Wang, Ying-tang Gao, Zhuo Yang, Tang Li, Chen-yi Yang, Yi-meng Chen

New
Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca2+ permeable AMPA receptor-system xc
NeuroscienceJun 23 2017Toxicology in Vitro

Xin-yue Wang, Yan-li Li, Hai-yun Wang, Min Zhu, Di Guo, Guo-lin Wang, Ying-tang Gao, Zhuo Yang, Tang Li, Chen-yi Yang, Yi-meng Chen

BACE inhibition-dependent repair of Alzheimer’s pathophysiology
NeuroscienceJun 22 2017PNAS

Aylin D. Keskin, Maja Kekuš, Helmuth Adelsberger, Ulf Neumann, Derya R. Shimshek, Beomjong Song, Benedikt Zott, Tingying Peng, Hans Förstl, Matthias Staufenbiel, Israel Nelken, Bert Sakmann, Arthur Konnerth, and Marc Aurel Busche

New
BACE inhibition-dependent repair of Alzheimer’s pathophysiology
NeuroscienceJun 22 2017Proceedings of the National Academy of Sciences

Aylin D. Keskin, Maja Kekuš, Helmuth Adelsberger, Ulf Neumann, Derya R. Shimshek, Beomjong Song, Benedikt Zott, Tingying Peng, Hans Förstl, Matthias Staufenbiel, Israel Nelken, Bert Sakmann, Arthur Konnerth, and Marc Aurel Busche

New
A Labeled-Line Neural Circuit for Pheromone-Mediated Sexual Behaviors in Mice
NeuroscienceJun 22 2017Neuron

Kentaro K. Ishii, Takuya Osakada, Hiromi Mori, Nobuhiko Miyasaka, Yoshihiro Yoshihara, Kazunari Miyamichi, Kazushige Touhara

New
Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway
NeuroscienceJun 22 2017Nature Communications

Yosuke M. Morizawa, Yuri Hirayama, Noubuhiko Ohno, Shinsuke Shibata, Eiji Shigetomi, Yang Sui, Junichi Nabekura, Koichi Sato, Fumikazu Okajima, Hirohide Takebayashi, Hideyuki Okano & Schuichi Koizumi

New
Human iPS‐derived endothelial cells for 3D microphysiological systems
Stem CellsJun 21 2017Tissue Engineering

Yosuke K. Kurokawa, Rose T. Yin, Michael R. Shang, Venktesh S. Shirure, Monica L. Moya, and Steven C. George

Human iPS‐derived endothelial cells for 3D microphysiological systems
Stem CellsJun 21 2017Tissue Engineering

Yosuke K. Kurokawa, Rose T. Yin, Michael R. Shang, Venktesh S. Shirure, Monica L. Moya, and Steven C. George

New
High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates
NeuroscienceJun 21 2017Neuron

Kaoru Seiriki, Atsushi Kasai, Takeshi Hashimoto, Wiebke Schulze, Misaki Niu, Shun Yamaguchi, Takanobu Nakazawa, Ken-ichi Inoue, Shiori Uezono, Masahiko Takada, Yuichiro Naka, Hisato Igarashi, Masato Tanuma, James A. Waschek, Yukio Ago, Kenji F. Tanaka, Atsuko Hayata-Takano, Kazuki Nagayasu, Norihito Shintani, Ryota Hashimoto, Yasuto Kunii, Mizuki Hino, Junya Matsumoto, Hirooki Yabe, Takeharu Nagai, Katsumasa Fujita, Toshio Matsuda, Kazuhiro Takuma, Akemichi Baba, Hitoshi Hashimoto

New
EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila
Developmental BiologyJun 19 2017Developmental Cell

Michiko Sekiya, Akiko Maruko-Otake, Stephen Hearn, Yasufumi Sakakibara, Naoki Fujisaki, Emiko Suzuki, Kanae Ando, Koichi M. Iijima

New
Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin–N-cadherin pathway after spinal cord injury
Biomedical ResearchJun 19 2017Nature Medicine

Masamitsu Hara, Kazu Kobayakawa, Yasuyuki Ohkawa, Hiromi Kumamaru, Kazuya Yokota, Takeyuki Saito, Ken Kijima, Shingo Yoshizaki, Katsumi Harimaya, Yasuharu Nakashima & Seiji Okada

New
Inhibition of cyclooxygenase‑2 sensitizes lung cancer cells to radiation‑induced apoptosis
Cancer & ImmunologyJun 15 2017Oncology Letters

ZHI‑QIANG HAN, HONGWEI LIAO, FENG SHI, XIAO‑PING CHEN, HUA‑CHENG HU, MING‑QING TIAN, LI‑HUA WANG and SONGMIN YING

Inhibition of cyclooxygenase‑2 sensitizes lung cancer cells to radiation‑induced apoptosis
Cancer & ImmunologyJun 15 2017Oncology Letters

ZHI‑QIANG HAN, HONGWEI LIAO, FENG SHI, XIAO‑PING CHEN, HUA‑CHENG HU, MING‑QING TIAN, LI‑HUA WANG and SONGMIN YING

New
Creation of a Synthetic Ligand for Mitochondrial DNA Sequence Recognition and Promoter-Specific Transcription Suppression
Biochemistry & Molecular BiologyJun 14 2017Journal of The American Chemical Society

Takuya Hidaka, Ganesh N. Pandian, Junichi Taniguchi, Tomohiro Nobeyama, Kaori Hashiya, Toshikazu Bando, and Hiroshi Sugiyama

New
Bioengineered silkworms with butterfly cytotoxin-modified silk glands produce sericin cocoons with a utility for a new biomaterial
Biochemistry & Molecular BiologyJun 12 2017PNAS

Ryosuke Otsuki, Masafumi Yamamoto, Erika Matsumoto, Shin-ichi Iwamoto, Hideki Sezutsu, Masumi Suzui, Keiko Takaki, Keiji Wakabayashi, Hajime Mori, and Eiji Kotani

New
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense
Cancer & ImmunologyJun 12 2017Nature Immunology

Miwa Sasai, Naoya Sakaguchi, Ji Su Ma, Shuhei Nakamura, Tsuyoshi Kawabata, Hironori Bando, Youngae Lee, Tatsuya Saitoh, Shizuo Akira, Akiko Iwasaki, Daron M Standley, Tamotsu Yoshimori & Masahiro Yamamoto

New
Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice
NeuroscienceJun 12 2017Nature Communications

Naoko Morimura, Hiroki Yasuda, Kazuhiko Yamaguchi, Kei-ichi Katayama, Minoru Hatayama, Naoko H. Tomioka, Maya Odagawa, Akiko Kamiya, Yoshimi Iwayama, Motoko Maekawa, Kazuhiko Nakamura, Hideo Matsuzaki, Masatsugu Tsujii, Kazuyuki Yamada, Takeo Yoshikawa & Jun Aruga

New
Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants
Cell BiologyJun 09 2017Autophagy

Masaaki Uematsu, Taki Nishimura, Yuriko Sakamaki, Hayashi Yamamoto & Noboru Mizushima

New
NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes
Developmental BiologyJun 06 2017Nature Communications

Zhi Zhou, Hiroshi Kawabe, Atsushi Suzuki, Kaori Shinmyozu & Yumiko Saga

New
Asymmetric distribution of type IV pili triggered by directional light in unicellular cyanobacteria
Biochemistry & Molecular BiologyJun 05 2017PNAS

Daisuke Nakane and Takayuki Nishizaka

New
Placental labyrinth formation in mice requires endothelial FLRT2–UNC5B signaling
Developmental BiologyJun 02 2017Development

Ikue Tai-Nagara, Yusuke Yoshikawa, Naoko Numata, Tomofumi Ando, Keisuke Okabe, Yuki Sugiura, Masaki Ieda, Nobuyuki Takakura, Osamu Nakagawa, Bin Zhou, Koji Okabayashi, Makoto Suematsu, Yuko Kitagawa, Martin Bastmeyer, Kohji Sato, Rüdiger Klein, Sutip Navankasattusas, Dean Y. Li, Satoru Yamagishi, Yoshiaki Kubota

New
Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of Held
NeuroscienceJun 02 2017The Journal of Neuroscience

Kohgaku Eguchi, Zacharie Taoufiq, Oliver Thorn-Seshold, Dirk Trauner, Masato Hasegawa and Tomoyuki Takahashi

New
A RHO Small GTPase Regulator ABR Secures Mitotic Fidelity in Human Embryonic Stem Cells
Stem CellsJun 01 2017Stem Cell Reports

Masatoshi Ohgushi, Maki Minaguchi, Mototsugu Eiraku, Yoshiki Sasai

New
Light-driven liquid metal nanotransformers for biomedical theranostics
Biomedical ResearchBiochemistry & Molecular BiologyMai 31 2017Nature Communications

Svetlana A. Chechetka, Yue Yu, Xu Zhen, Manojit Pramanik, Kanyi Pu & Eijiro Miyako

New
Characterization of miR-122-independent propagation of HCV
MicrobiologyMai 29 2017PLOS Pathogens

Chikako Ono, Takasuke Fukuhara, Daisuke Motooka, Shota Nakamura, Daisuke Okuzaki, Satomi Yamamoto, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Kentaro Uemura, Yuzy Fauzyah, Takeshi Kurihara, Takahiro Suda, Akira Nishio, Su Su Hmwe, Toru Okamoto, Tomohide Tatsumi, Tetsuo Takehara, Kazuaki Chayama, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura

New
Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction
Cancer & ImmunologyMai 26 2017The Journal of Experimental Medicine

Takuma Tsuda, Mikito Takefuji, Nina Wettschureck, Kazuhiko Kotani, Ryota Morimoto, Takahiro Okumura, Harmandeep Kaur, Shunsuke Eguchi, Teruhiro Sakaguchi, Sohta Ishihama, Ryosuke Kikuchi, Kazumasa Unno, Kunihiro Matsushita, Shizukiyo Ishikawa, Stefan Offermanns, Toyoaki Murohara

New
Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide
Biochemistry & Molecular BiologyMai 22 2017Nature Chemistry

Misao Akishiba, Toshihide Takeuchi, Yoshimasa Kawaguchi, Kentarou Sakamoto, Hao-Hsin Yu, Ikuhiko Nakase, Tomoka Takatani-Nakase, Fatemeh Madani, Astrid Gräslund & Shiroh Futaki

New
Lysophosphatidylinositol-induced activation of the cation channel TRPV2 triggers glucagon-like peptide-1 secretion in enteroendocrine L cells
Biochemistry & Molecular BiologyMai 22 2017The Journal of Biological Chemistry

Kazuki Harada, Tetsuya Kitaguchi, Taichi Kamiya, Kyaw Htet Aung, Kazuaki Nakamura, Kunihiro Ohta, and Takashi Tsuboi

New
In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome
Biochemistry & Molecular BiologyMai 18 2017Molecular Cell

Hikaru Tsuchiya, Fumiaki Ohtake, Naoko Arai, Ai Kaiho, Sayaka Yasuda, Keiji Tanaka, Yasushi Saeki

New
Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis
NeuroscienceMai 17 2017Autophagy

Junji Yamaguchi, Chigure Suzuki, Tomohisa Nanao, Soichirou Kakuta, Kentarou Ozawa, Isei Tanida, Tatsuya Saitoh, Takehiko Sunabori, Masaaki Komatsu, Keiji Tanaka, Shigeki Aoki, Kenji Sakimura & Yasuo Uchiyama

New
Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17
Cell BiologyMai 15 2017Nature Communications

Kohei Arasaki, Yumi Mikami, Stephanie R. Shames, Hiroki Inoue, Yuichi Wakana Mitsuo Tagaya

New
A Single Spherical Assembly of Protein Amyloid Fibrils Formed by Laser Trapping
Biochemistry & Molecular BiologyMai 15 2017Angewandte Chemie International Edition

Ken-ichi Yuyama, Mariko Ueda, Satoshi Nagao, Shun Hirota, Teruki Sugiyama, Hiroshi Masuhara

New
Holliday junction resolvases mediate chloroplast nucleoid segregation
Plant & Animal ScienceMai 12 2017Science

Yusuke Kobayashi, Osami Misumi, Masaki Odahara, Kota Ishibashi, Masafumi Hirono, Kumi Hidaka, Masayuki Endo, Hiroshi Sugiyama, Hiroshi Iwasaki, Tsuneyoshi Kuroiwa, Toshiharu Shikanai, Yoshiki Nishimura

New
An Adenosine Receptor for Olfaction in Fish
NeuroscienceMai 11 2017Current Biology

Noriko Wakisaka, Nobuhiko Miyasaka, Tetsuya Koide, Miwa Masuda, Towako Hiraki-Kajiyama, Yoshihiro Yoshihara

New
Autophagosome formation is initiated at phosphatidylinositol synthase‐enriched ER subdomains
Cell BiologyMai 11 2017The EMBO Journal

Taki Nishimura, Norito Tamura, Nozomu Kono, Yuta Shimanaka, Hiroyuki Arai, Hayashi Yamamoto, Noboru Mizushima

New
DOK7 gene therapy enhances motor activity and life span in ALS model mice
Biomedical ResearchMai 10 2017EMBO Molecular Medicine

Sadanori Miyoshi, Tohru Tezuka, Sumimasa Arimura, Taro Tomono, Takashi Okada, Yuji Yamanashi

Multiple roles of afadin in the ultrastructural morphogenesis of mouse hippocampal mossy fiber synapses
NeuroscienceMai 08 2017Journal of Comparative Neurology

Kousyoku Sai, Shujie Wang, Aika Kaito, Takeshi Fujiwara, Tomohiko Maruo, Yu Itoh, Muneaki Miyata, Shotaro Sakakibara, Naoyuki Miyazaki, Kazuyoshi Murata, Yuuki Yamaguchi, Tomohiro Haruta, Hideo Nishioka, Yuki Motojima, Miyuki Komura, Kazushi Kimura, Kenji Mandai, Yoshimi Takai, Akira Mizoguchi

New
Multiple roles of afadin in the ultrastructural morphogenesis of mouse hippocampal mossy fiber synapses
NeuroscienceMai 08 2017Journal of Comparative Neurology

Kousyoku Sai, Shujie Wang, Aika Kaito, Takeshi Fujiwara, Tomohiko Maruo, Yu Itoh, Muneaki Miyata, Shotaro Sakakibara, Naoyuki Miyazaki, Kazuyoshi Murata, Yuuki Yamaguchi, Tomohiro Haruta, Hideo Nishioka, Yuki Motojima, Miyuki Komura, Kazushi Kimura, Kenji Mandai, Yoshimi Takai, Akira Mizoguchi

New
Large Cytoplasm Is Linked to the Error-Prone Nature of Oocytes
Developmental BiologyMai 08 2017Developmental Cell

Hirohisa Kyogoku, Tomoya S. Kitajima

New
Reconstructing 3D deformation dynamics for curved epithelial sheet morphogenesis from positional data of sparsely-labeled cells
Developmental BiologyMai 02 2017Nature Communications

Yoshihiro Morishita, Ken-ichi Hironaka, Sang-Woo Lee, Takashi Jin Daisuke Ohtsuka

New
Inter-species hormonal control of host root morphology by parasitic plants
Plant & Animal ScienceMai 01 2017PNAS

Thomas Spallek, Charles W. Melnyk, Takanori Wakatake, Jing Zhang, Yuki Sakamoto, Takatoshi Kiba, Satoko Yoshida, Sachihiro Matsunaga, Hitoshi Sakakibara, Ken Shirasu,

New
ChIP-seq analysis of genomic binding regions of five major transcription factors in mouse epiblast stem cells that highlights a central role for ZIC2
Developmental BiologyAbr 28 2017Development

Kazunari Matsuda, Tomoyuki Mikami, Shinya Oki, Hideaki Iida, Munazah Andrabi, Jeremy M. Boss, Katsushi Yamaguchi, Shuji Shigenobu, Hisato Kondoh

New
Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient model of biliary atresia
Developmental BiologyAbr 21 2017Development

Hiroki Higashiyama, Aisa Ozawa, Hiroyuki Sumitomo, Mami Uemura, Ko Fujino, Hitomi Igarashi, Kenya Imaimatsu, Naoki Tsunekawa, Yoshikazu Hirate, Masamichi Kurohmaru, Yukio Saijoh, Masami Kanai-Azuma, Yoshiakira Kanai

New
Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity
Cell BiologyAbr 21 2017Cell Death & Differentiation

Kaori Kanemaru, Yoshikazu Nakamura, Kengo Totoki, Takatsugu Fukuyama, Madoka Shoji, Hisae Kaneko, Kanako Shiratori, Atsuko Yoneda, Takafumi Inoue, Yoichiro Iwakura, Kenji Kabashima and Kiyoko Fukami

New
Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell–cell adhesions in vitro and induces haemorrhage in vivo
Biochemistry & Molecular BiologyAbr 20 2017The FEBS Journal

Tadahiko Seo, Taketo Sakon, Shiori Nakazawa, Asuka Nishioka, Kohei Watanabe, Kaori Matsumoto, Mari Akasaka, Narumi Shioi, Hitoshi Sawada, Satohiko Araki

New
Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes
Cell BiologyAbr 17 2017Nature Cell Biology

Shunsuke Kon, Kojiro Ishibashi, Hiroto Katoh, Sho Kitamoto, Takanobu Shirai, Shinya Tanaka, Mihoko Kajita, Susumu Ishikawa, Hajime Yamauchi, Yuta Yako, Tomoko Kamasaki, Tomohiro Matsumoto, Hirotaka Watanabe, Riku Egami, Ayana Sasaki, Atsuko Nishikawa, Ikumi Kameda, Takeshi Maruyama, Rika Narumi, Tomoko Morita, Yoshiteru Sasaki, Ryosuke Enoki, Sato Honma, Hiromi Imamura, Masanobu Oshima, Tomoyoshi Soga, Jun-ichi Miyazaki, Michael R. Duchen, Jin-Min Nam, Yasuhito Onodera, Shingo Yoshioka, Junichi Kikuta, Masaru Ishii, Masamichi Imajo, Eisuke Nishida, Yoichiro Fujioka, Yusuke Ohba, Toshiro Sato Yasuyuki Fujita

New
Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior
NeuroscienceAbr 13 2017The Journal of Experimental Medicine

Yuki Fujita, Koji Masuda, Masashige Bando, Ryuichiro Nakato, Yuki Katou, Takashi Tanaka, Masahiro Nakayama, Keizo Takao, Tsuyoshi Miyakawa, Tatsunori Tanaka, Yukio Ago,Hitoshi Hashimoto, Katsuhiko Shirahige, Toshihide Yamashita

New
Unusual semi‐extractability as a hallmark of nuclear body‐associated architectural noncoding RNAs
Biochemistry & Molecular BiologyAbr 12 2017The EMBO Journal

Takeshi Chujo, Tomohiro Yamazaki, Tetsuya Kawaguchi, Satoshi Kurosaka, Toru Takumi, Shinichi Nakagawa, Tetsuro Hirose

New
Chemical labelling for visualizing native AMPA receptors in live neurons
NeuroscienceAbr 07 2017Nature Communications

Sho Wakayama, Shigeki Kiyonaka, Itaru Arai, Wataru Kakegawa, Shinji Matsuda, Keiji Ibata, Yuri L. Nemoto, Akihiro Kusumi, Michisuke Yuzaki Itaru Hamachi

New
Compositionally distinct nuclear pore complexes of functionally distinct dimorphic nuclei in ciliate Tetrahymena
Cell BiologyAbr 06 2017Journal of Cell Science

Masaaki Iwamoto, Hiroko Osakada, Chie Mori, Yasuhiro Fukuda, Koji Nagao, Chikashi Obuse, Yasushi Hiraoka, Tokuko Haraguchi

New
An NADPH Oxidase RBOH Functions in Rice Roots during Lysigenous Aerenchyma Formation under Oxygen-Deficient Conditions
Plant & Animal ScienceMar 28 2017The Plant Cell

Takaki Yamauchi, Miki Yoshioka, Aya Fukazawa, Hitoshi Mori, Naoko K. Nishizawa, Nobuhiro Tsutsumi, Hirofumi Yoshioka, and Mikio Nakazono

New
Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance
Developmental BiologyMar 27 2017Developmental Cell

Hiroyuki Nakajima, Kimiko Yamamoto, Sobhika Agarwala, Kenta Terai, Hajime Fukui, Shigetomo Fukuhara, Koji Ando, Takahiro Miyazaki, Yasuhiro Yokota, Etienne Schmelzer, Heinz-Georg Belting, Markus Affolter, Virginie Lecaudey, Naoki Mochizuki

New
Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins
Cell BiologyMar 27 2017PNAS

Katsuhiro Kawaai, Hideaki Ando, Nobuhiko Satoh, Hideomi Yamada, Naoko Ogawa, Matsumi Hirose, Akihiro Mizutani, Benjamin Bonneau, George Seki, and Katsuhiko Mikoshiba

New
A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF165)
Biochemistry & Molecular BiologyMar 27 2017Nature Chemistry

Hiroyuki Koide, Keiichi Yoshimatsu, Yu Hoshino, Shih-Hui Lee, Ai Okajima, Saki Ariizumi, Yudai Narita, Yusuke Yonamine, Adam C. Weisman, Yuri Nishimura, Naoto Oku, Yoshiko Miura & Kenneth J. Shea

New
Polar Localization of the NIP5;1 Boric Acid Channel is Maintained by Endocytosis and Facilitates Boron Transport in Arabidopsis Roots
Plant & Animal ScienceMar 24 2017The Plant Cell

Sheliang Wang, Akira Yoshinari, Tomoo Shimada, Ikuko Hara-Nishimura, Namiki Mitani-Ueno, Jian Feng Ma, Satoshi Naito, and Junpei Takano

New
Raft-based sphingomyelin interactions revealed by new fluorescent sphingomyelin analogs
Cell BiologyMar 22 2017The Journal of Cell Biology

Masanao Kinoshita, Kenichi G.N. Suzuki, Nobuaki Matsumori, Misa Takada, Hikaru Ano, Kenichi Morigaki, Mitsuhiro Abe, Asami Makino, Toshihide Kobayashi, Koichiro M. Hirosawa, Takahiro K. Fujiwara, Akihiro Kusumi, Michio Murata

New
Tubulin isotype substitution revealed that isotype composition modulates microtubule dynamics in C. elegans embryos
Cell BiologyMar 16 2017Journal of Cell Science

Yu Honda, Kenta Tsuchiya, Eisuke Sumiyoshi, Nami Haruta, Asako Sugimoto

New
Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote
Plant & Animal ScienceMar 15 2017Gene & Development

Minako Ueda, Ernst Aichinger, Wen Gong, Edwin Groot, Inge Verstraeten, Lam Dai Vu, Ive De Smet, Tetsuya Higashiyama, Masaaki Umeda, and Thomas Laux

New
A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking
Developmental BiologyMar 13 2017Developmental Cell

Katsura Minegishi, Masakazu Hashimoto, Rieko Ajima, Katsuyoshi Takaoka, Kyosuke Shinohara, Yayoi Ikawa, Hiromi Nishimura, Andrew P. McMahon, Karl Willert, Yasushi Okada, Hiroshi Sasaki, Dongbo Shi, Toshihiko Fujimori, Toshihisa Ohtsuka, Yasunobu Igarashi, Terry P. Yamaguchi, Akihiko Shimono, Hidetaka Shiratori, Hiroshi Hamada

New
Extracellular Signals induce Glycoprotein M6a Clustering of Lipid-rafts and associated Signaling Molecules
NeuroscienceMar 08 2017The Journal of Neuroscience

Atsuko Honda, Yasuyuki Ito, Kazuko Takahashi-Niki, Natsuki Matsushita, Motohiro Nozumi, Hidenori Tabata, Kosei Takeuchi and Michihiro Igarashi

New
Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells
Cell BiologyMar 07 2017PNAS

Sayaka Saitoh, Takeshi Maruyama, Yuta Yako, Mihoko Kajita, Yoichiro Fujioka, Yusuke Ohba, Nobuhiro Kasai, Natsu Sugama, Shunsuke Kon, Susumu Ishikawa, Takashi Hayashi, Tomohiro Yamazaki, Masazumi Tada, and Yasuyuki Fujita

New
Synthesis of Injectable Alginate Hydrogels with Muscle-Derived Stem Cells for Potential Myocardial Infarction Repair
Stem CellsMar 04 2017Applied Sciences

Rui Fang, Weiming Tian, and Xiongbiao Chen

Synthesis of Injectable Alginate Hydrogels with Muscle-Derived Stem Cells for Potential Myocardial Infarction Repair
Stem CellsMar 04 2017Applied Sciences

Rui Fang, Weiming Tian, and Xiongbiao Chen

New
Coordinated Movement of Vesicles and Actin Bundles during Nerve Growth Revealed by Superresolution Microscopy
Cell BiologyFev 28 2017Cell Reports

Motohiro Nozumi, Fubito Nakatsu, Kaoru Katoh, Michihiro Igarashi

New
IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting
Cancer & ImmunologyFev 24 2017Nature Communications

Hirohisa Kyogoku, Tomoya S. Kitajima

New
Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma
Cancer & ImmunologyFev 23 2017The Journal of Experimental Medicine

Takehiro Takahashi, Yoshihide Asano, Koji Sugawara, Takashi Yamashita, Kouki Nakamura, Ryosuke Saigusa, Yohei Ichimura, Tetsuo Toyama, Takashi Taniguchi, Kaname Akamata, Shinji Noda, Ayumi Yoshizaki, Daisuke Tsuruta, Maria Trojanowska, Shinichi Sato

New
Allograft inflammatory factor 1 is a regulator of transcytosis in M cells
Cancer & ImmunologyFev 22 2017Nature Communications

Sari Kishikawa, Shintaro Sato, Satoshi Kaneto, Shigeo Uchino, Shinichi Kohsaka, Seiji Nakamura Hiroshi Kiyono

New
Distinct intracellular Ca2+ dynamics regulate apical constriction and differentially contribute to neural tube closure
Developmental BiologyFev 20 2017Development

Makoto Suzuki, Masanao Sato, Hiroshi Koyama, Yusuke Hara, Kentaro Hayashi, Naoko Yasue, Hiromi Imamura, Toshihiko Fujimori, Takeharu Nagai, Robert E. Campbell, Naoto Ueno

New
Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylation
Cell BiologyFev 16 2017The Journal of Cell Biology

Taiichi Tsuyama, Asako Tsubouchi,Tadao Usui, Hiromi Imamura, Tadashi Uemura

New
Polydom is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling
Biomedical ResearchFev 08 2017Circulation Research

Nanami Morooka, Sugiko Futaki, Ryoko Sato-Nishiuchi, Masafumi Nishino, Yuta Totani, Chisei Shimono, Itsuko Nakano, Hiroyuki Nakajima, Naoki Mochizuki, Kiyotoshi Sekiguchi

New
Eccentric position of the germinal vesicle and cortical flow during oocyte maturation specify the animal-vegetal axis of ascidian embryos
Developmental BiologyFev 07 2017Development

Masumi Tokuhisa, Miyuki Muto, Hiroki Nishida

New
Reelin transiently promotes N-cadherin-dependent neuronal adhesion during mouse cortical development
NeuroscienceFev 06 2017PNAS

Yuki Matsunaga, Mariko Noda, Hideki Murakawa, Kanehiro Hayashi, Arata Nagasaka, Seika Inoue, Takaki Miyata, Takashi Miura, Ken-ichiro Kubo, and Kazunori Nakajima

New
RAD54 forms DNA repair foci in response to DNA damage in living plant cells
Plant & Animal ScienceFev 02 2017

Takeshi Hirakawa、Junko Hasegawa、Charles I. White and Sachihiro Matsunaga

New
Autocrine and paracrine interactions between multiple myeloma cells and bone marrow stromal cells by growth arrest-specific gene 6 crosstalk with interleukin-6
Biochemistry & Molecular BiologyJan 31 2017The Journal of Biological Chemistry

Miki Furukawa, Hiroshi Ohkawara, Kazuei Ogawa, Kazuhiko Ikeda, Koki Ueda, Akiko Shichishima-Nakamura, Emi Ito, Jun-ichi Imai, Yuka Yanagisawa, Reiko Honma, Shinya Watanabe, Satoshi Waguri, Takayuki Ikezoe, and Yasuchika Takeishi

New
NDR1-dependent regulation of kindlin-3 controls high-affinity LFA-1 binding and immune synapse organization
Cell BiologyJan 30 2017Molecular and Cellular Biology

Naoyuki Kondo, Yoshihiro Ueda, Toshiyuki Kita, Madoka Ozawa, Takashi Tomiyama, Kaneki Yasuda, Dae-Sik Lim, and Tatsuo Kinashi

New
A Lin28 homolog reprograms differentiated cells to stem cells in the moss Physcomitrella patens
Stem CellsJan 27 2017Nature Communications

Chen Li, Yusuke Sako, Akihiro Imai, Tomoaki Nishiyama, Kari Thompson, Minoru Kubo, Yuji Hiwatashi, Yukiko Kabeya, Dale Karlson, Shu-Hsing Wu, Masaki Ishikawa, Takashi Murata, Philip N. Benfey, Yoshikatsu Sato, Yosuke Tamada, and Mitsuyasu Hasebe

New
A gustatory neural circuit of Caenorhabditis elegans generates memory-dependent behaviors in Na+ Chemotaxis
NeuroscienceJan 26 2017The Journal of Neuroscience

Lifang Wang, Hirofumi Sato, Yohsuke Satoh, Masahiro Tomioka, Hirofumi Kunitomo, Yuichi Iino

New
Gap junction-mediated signaling from motor neurons regulates motor generation in the central circuits of larval Drosophila
NeuroscienceJan 23 2017The Journal of Neuroscience

Teruyuki Matsunaga, Hiroshi Kohsaka and Akinao Nose

New
Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis
Developmental BiologyJan 17 2017Cell Reports

Jun Ueda, Akihito Harada, Takashi Urahama, Shinichi Machida, Kazumitsu Maehara, Masashi Hada, Yoshinori Makino, Jumpei Nogami, Naoki Horikoshi, Akihisa Osakabe, Hiroyuki Taguchi, Hiroki Tanaka, Hiroaki Tachiwana, Tatsuma Yao, Minami Yamada, Takashi Iwamoto, Ayako Isotani, Masahito Ikawa, Taro Tachibana, Yuki Okada, Hiroshi Kimura, Yasuyuki Ohkawa, Hitoshi Kurumizaka, Kazuo Yamagata

New
Basal filopodia and vascular mechanical stress organize fibronectin into pillars bridging the mesoderm-endoderm gap
Developmental BiologyJan 17 2017Development

Yuki Sato, Kei Nagatoshi, Ayumi Hamano, Yuko Imamura, David Huss, Seiichi Uchida, Rusty Lansford

New
Inhibition of cell polarity establishment in stomatal asymmetric cell division using the chemical compound bubblin
Developmental BiologyJan 13 2017Development

Yumiko Sakai, Shigeo S. Sugano, Takashi Kawase, Makoto Shirakawa, Yu Imai, Yusuke Kawamoto, Hiroshi Sugiyama, Tsuyoshi Nakagawa, Ikuko Hara-Nishimura, Tomoo Shimada

New
TBP-like protein (TLP) disrupts the p53-MDM2 interaction and induces long-lasting p53 activation
Biochemistry & Molecular BiologyJan 12 2017The Journal of Biological Chemistry

Ryo Maeda, Hiroyuki Tamashiro, Kazunori Takano, Hiro Takahashi, Hidefumi Suzuki, Shinta Saito, Waka Kojima, Noritaka Adachi, Kiyoe Ura, Takeshi Endo, and Taka-aki Tamura

New
Environmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans
Biochemistry & Molecular BiologyJan 09 2017Nature Communications

Saya Kishimoto, Masaharu Uno, Emiko Okabe, Masanori Nono Eisuke Nishida

New
Intravital Imaging of Neutrophil Recruitment Reveals the Efficacy of FPR1 Blockade in Hepatic Ischemia-Reperfusion Injury
Cancer & ImmunologyJan 06 2017The Journal of Immunology

Masaki Honda, Takayuki Takeichi, Shintaro Hashimoto, Daiki Yoshii, Kaori Isono, Shintaro Hayashida, Yuki Ohya, Hidekazu Yamamoto, Yasuhiko Sugawara and Yukihiro Inomata

New
GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration
Cell BiologyJan 03 2017The Journal of Cell Biology

Shuji Wakatsuki, Shinji Tokunaga, Megumi Shibata, Toshiyuki Araki

New
Suppression of Dopamine Neurons Mediates Reward
NeuroscienceDez 20 2016PLoS Biology

Nobuhiro Yamagata, Makoto Hiroi, Shu Kondo, Ayako Abe, Hiromu Tanimoto

New
Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth
NeuroscienceDez 19 2016The Journal of Neuroscience

Kotaro Furusawa, Akiko Asada, Pamela Urrutia, Christian Gonzalez-Billault, Mitsunori Fukuda, and Shin-ichi Hisanaga

New
Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish
Developmental BiologyDez 19 2016Development

Ayano Chiba, Haruko Watanabe-Takano, Kenta Terai, Hajime Fukui, Takahiro Miyazaki, Mami Uemura, Hisashi Hashimoto, Masahiko Hibi, Shigetomo Fukuhara, Naoki Mochizuki

New
Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ
NeuroscienceDez 19 2016Nature Neuroscience

Takashi Matsuda, Takeshi Y Hiyama, Fumio Niimura, Taiji Matsusaka, Akiyoshi Fukamizu, Kenta Kobayashi, Kazuto Kobayashi & Masaharu Noda

New
PIGN prevents protein aggregation in the endoplasmic reticulum independently of its function in the GPI synthesis
Cell BiologyDez 15 2016Journal of Cell Science

Shinji Ihara, Sohei Nakayama, Yoshiko Murakami, Emiko Suzuki, Masayo Asakawa, Taroh Kinoshita, Hitoshi Sawa

New
Five colour variants of bright luminescent protein for real-time multicolour bioimaging
BioimagingDez 14 2016Nature Communications

Kazushi Suzuki, Taichi Kimura, Hajime Shinoda, Guirong Bai, Matthew J. Daniels, Yoshiyuki Arai, Masahiro Nakano Takeharu Nagai

New
Valproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy
NeuroscienceDez 09 2016Neuroscience Letters

Y. Zhang, J.Y. Wu, L.H. Weng, X.X. Li, L.J. Yu, Y. Xu

New
Optical inactivation of synaptic AMPA receptors erases fear memory
NeuroscienceDez 05 2016Nature

Kiwamu Takemoto, Hiroko Iwanari, Hirobumi Tada, Kumiko Suyama, Akane Sano, Takeharu Nagai, Takao Hamakubo Takuya Takahashi

New
Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal
Developmental BiologyDez 01 2016Gene & Development

Mito Kanatsu-Shinohara, Takashi Tanaka, Narumi Ogonuki, Atsuo Ogura, Hiroko Morimoto, Pei Feng Cheng, Robert N. Eisenman, Andreas Trumpp, and Takashi Shinohara

New
Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy
Cell BiologyNov 30 2016The Journal of Cell Biology

Shun-ichi Yamashita, Xiulian Jin, Kentaro Furukawa, Maho Hamasaki, Akiko Nezu, Hidenori Otera, Tetsu Saigusa, Tamotsu Yoshimori, Yasuyoshi Sakai, Katsuyoshi Mihara, Tomotake Kanki

New
Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors
NeuroscienceNov 09 2016The Journal of Neuroscience

Bin Ji, Hiroyuki Kaneko, Takafumi Minamimoto, Haruhisa Inoue, Hiroki Takeuchi, Katsushi Kumata, Ming-Rong Zhang, Ichio Aoki, Chie Seki, Maiko Ono, Masaki Tokunaga, Satoshi Tsukamoto, Koji Tanabe, Ryong-Moon Shin, Takeharu Minamihisamatsu, Seiji Kito, Barry J. Richmond, Tetsuya Suhara and Makoto Higuchi

New
AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin
Cancer & ImmunologyNov 04 2016eLife

Nicolas Aznar, Arjun Patel, Cristina C Rohena, Ying Dunkel, Linda P Joosen, Vanessa Taupin, Irina Kufareva, Marilyn G Farquhar, Pradipta Ghosh

New
An Autophagic Flux Probe that Releases an Internal Control
Cell BiologyNov 03 2016Molecular Cell

Takeshi Kaizuka, Hideaki Morishita, Yutaro Hama, Satoshi Tsukamoto, Takahide Matsui, Yuichiro Toyota, Akihiko Kodama, Tomoaki Ishihara, Tohru Mizushima, Noboru Mizushima

New
Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex
NeuroscienceOut 25 2016PNAS

Hirobumi Tada, Tomoyuki Miyazaki, Kiwamu Takemoto, Kenkichi Takase, Susumu Jitsuki, Waki Nakajima, Mayu Koide, Naoko Yamamoto, Kasane Komiya, Kumiko Suyama, Akane Sano, Akiko Taguchi, and Takuya Takahashi

New
Mixed functional microarchitectures for orientation selectivity in the mouse primary visual cortex
NeuroscienceOut 21 2016Nature Communications

Satoru Kondo, Takashi Yoshida Kenichi Ohki

The ATG conjugation systems are important for degradation of the inner autophagosomal membrane
Cell BiologyOut 20 2016Science

Kotaro Tsuboyama*First author
Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.

Ikuko Koyama-Honda*Co-first author
Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.

Noboru Mizushima*Last author, Corresponding author
Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.

New
CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa
Stem CellsCell BiologyOut 19 2016Molecular and Cellular Biology

Samantha A. M. Young, Haruhiko Miyata, Yuhkoh Satouh, Robert John Aitken, Mark A. Baker, Masahito Ikawa

Reconstitution in vitro of the entire cycle of the mouse female germ line
Stem CellsOut 17 2016Nature

Orie Hikabe*First author
Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. 

Katsuhiko Hayashi*Last author, Corresponding author
Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. 

New
Thermodynamic origin of surface melting on ice crystals
Environmental SciencesOut 17 2016PNAS

Ken-ichiro Murata, Harutoshi Asakawa, Ken Nagashima, Yoshinori Furukawa, and Gen Sazaki

Klf5 regulates muscle differentiation by directly targeting muscle-specific genes in cooperation with MyoD in mice
Biochemistry & Molecular BiologyOut 15 2016eLife

Shinichiro Hayashi*First author
Department of Cellular and Molecular Medicine, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan. 

Yumiko Oishi*Last author, Corresponding author
Department of Cellular and Molecular Medicine, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan. 

Escargot controls the sequential specification of two tracheal tip cell types by suppressing FGF signaling in Drosophila
Developmental BiologyOut 14 2016Development

Guangxia Miao* First author
Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.

Shigeo Hayashi*Last author, Corresponding author
Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.

Rescue of CAMDI deletion‐induced delayed radial migration and psychiatric behaviors by HDAC6 inhibitor
NeuroscienceOut 13 2016EMBO Reports

Toshifumi Fukuda*First author, Corresponding author
Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.

Shigeru Yanagi*Last author, Corresponding author
Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.

Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
Stem CellsOut 10 2016Nature

Yuji Shiba*First author, Corresponding author
Laboratory of Molecular Traffic, D1Institute for Biomedical Sciences, Shinshu University, Matsumoto 390-8621, Japan. 

Toshihito Gomibuchi*Co-first author
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.

Uichi Ikeda*Last author, Corresponding author
Department of Cardiovascular Surgery, Shinshu University School of Medicine, Matsumoto 390-8621, Japan. 

The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion
Developmental BiologyOut 06 2016Developmental Cell

Kotaro Sasaki*First author
Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Mitinori Saitou*Last author, Corresponding author
Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1
Stem CellsOut 04 2016Nature Communications

Bumpei Samata* First author
Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

Jun Takahashi*Last author, Corresponding author
Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

Cancer‐specific mutations in p53 induce the translation of Δ160p53 promoting tumorigenesis
Cancer & ImmunologyOut 04 2016EMBO Reports

Marco M Candeias*First author, Corresponding author
Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.

Michiyuki Matsuda*Last author
Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.

Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells
Cell BiologyOut 03 2016The Journal of Cell Biology

Masataka Kunii*First author
Department of Molecular and Cellular Biology, Institute for Molecular and Cellular Regulation, Gunma University, Gunma 371-8512, Japan.

Akihiro Harada*Last author, Corresponding author
Department of Molecular and Cellular Biology, Institute for Molecular and Cellular Regulation, Gunma University, Gunma 371-8512, Japan.

New
Hyperactive mutant of a wheat plasma membrane Na+/H+antiporterimproves the growth and salt tolerance of transgenic tobacco
Plant & Animal ScienceSet 29 2016Plant Science

Yang Zhou, Zesen Lai, Xiaochang Yin, Shan Yu, Yuanyuan Xu, Xiaoxiao Wang, Xinli Cong, Yuehua Luo, Haixia Xu, Xingyu Jiang∗

Characterization of novel dystonia musculorum mutant mice: Implications for central nervous system abnormality
NeuroscienceSet 28 2016Neurobiology of Disease

Masao Horie*First author
Division of Neurobiology and Anatomy, Niigata University, Niigata 951-8510, Japan.

Hirohide Takebayashi*Last author, Corresponding author
Division of Neurobiology and Anatomy, Niigata University, Niigata 951-8510, Japan.

Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways
Cell BiologySet 21 2016Nature Communications

Ippei Kikuchi* First author
Division of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan. 

Masanori Hatakeyama*Last author, Corresponding author
Division of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan. 

Neural substrate of dynamic Bayesian inference in the cerebral cortex
NeuroscienceSet 19 2016Nature Neuroscience

Akihiro Funamizu*First author
Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University, Tancha, Onna-son, Kunigami, Okinawa, Japan.

Kenji Doya*Last author, Corresponding author
Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University, Tancha, Onna-son, Kunigami, Okinawa, Japan.

The Core Molecular Machinery Used for Engulfment of Apoptotic Cells Regulates the JNK Pathway Mediating Axon Regeneration in Caenorhabditis elegans
NeuroscienceSet 14 2016The Journal of Neuroscience

Strahil Iv. Pastuhov*First author
Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan.

Kunihiro Matsumoto*Corresponding author
Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan.

Naoki Hisamoto*Last author, Corresponding author
Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan.

Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology
NeuroscienceSet 12 2016Human Molecular Genetics

Ying Mao*First author
Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

Hitoshi Okazawa*Last author, Corresponding author
Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose
Biochemistry & Molecular BiologySet 09 2016The Journal of Biological Chemistry

Johan Medina*First author
Institute for Molecular and Cellular Regulation, Gunma University Maebashi 371-8512, Japan.

Itaru Kojima*Last author, Corresponding author
Institute for Molecular and Cellular Regulation, Gunma University Maebashi 371-8512, Japan.

Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming
Developmental BiologySet 08 2016PLoS Biology

Quan Wu*First author
Division of Mammalian Development, National Institute of Genetics, Mishima, Japan.

Yumiko Saga*Last author, Corresponding author
Division of Mammalian Development, National Institute of Genetics, Mishima, Japan.

Tumor necrosis factor-alpha-induced protein 8-like 2 (TIPE2) is a novel negative regulator of TAK1 signal
Biochemistry & Molecular BiologySet 06 2016The Journal of Biological Chemistry

Michitaka Oho*First author
From Department of Applied Biological Sciences, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa-city, Kanagawa 252-0880, Japan.

Shigemasa Hanazawa*Last author, Corresponding author
From Department of Applied Biological Sciences, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa-city, Kanagawa 252-0880, Japan.

Epithelial tumors originate in tumor hotspots, a tissue-intrinsic microenvironment.
Cancer & ImmunologySet 01 2016PLoS Biology

Yoichiro Tamori*First author, Corresponding author
Structural Biology Center, National Institute of Genetics and Department of Genetics, School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), 1111 Yata, Mishima, Japan.

Wu-Min Deng*Last author, Corresponding author
Department of Biological Science, Florida State University, Tallahassee, Florida, United States of America

Atg9A trafficking through the recycling endosomes is required for autophagosome formation
Cell BiologySet 01 2016Journal of Cell Science

Kenta Imai*First author
Graduate School of Frontier Bioscience, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Takeshi Noda*Corresponding author
Graduate School of Frontier Bioscience, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Tamotsu Yoshimori*Last author, Corresponding author
Graduate School of Frontier Bioscience, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

IKKϵ inhibits PKC to promote Fascin-dependent actin bundling
Developmental BiologyAgo 30 2016Development

Tetsuhisa Otani*First author, Corresponding author
Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, Kobe, Hyogo 650-0047, Japan.

Shigeo Hayashi*Last author, Corresponding author
Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, Kobe, Hyogo 650-0047, Japan.

Multiciliated cell basal bodies align in stereotypical patterns coordinated by the apical cytoskeleton
Cell BiologyAgo 29 2016The Journal of Cell Biology

Elisa Herawati*First author
Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.

Daisuke Taniguchi*Co-first author
Department of Physics, School of Science and Technology, Meiji University, Kanagawa 214-8571, Japan.

Shuji Ishihara*Corresponding author
Department of Physics, School of Science and Technology, Meiji University, Kanagawa 214-8571, Japan.

Sachiko Tsukita*Last author, Corresponding author
Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.

Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
NeuroscienceAgo 24 2016Nature Communications

Seshiru Nakazawa*First author
Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma 371-8512, Japan.

Daisuke Oikawa*Co-first author
Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma 371-8512, Japan.

Hidefumi Ito*Corresponding author
Department of Neurology, Wakayama Medical University, 811-1, Kimiidera, Wakayama, Wakayama 641-8510, Japan.

Osamu Nureki*Corresponding author
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. 

Fuminori Tokunaga*Last author, Corresponding author
Laboratory of Molecular Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma 371-8512, Japan.

A developmental coordinate of pluripotency among mice, monkeys and humans
Stem CellsAgo 24 2016Nature

Tomonori Nakamura*First author
Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Mitinori Saitou*Last author, Corresponding author
Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

ARHGEF10 directs the localization of Rab8 to Rab6-positive executive vesicles
NeuroscienceAgo 22 2016Journal of Cell Science

Satoshi Shibata*First author, Corresponding author
From Group of Neurobiology, Division of Health Sciences, Graduate School of Medicine, Osaka University, Osaka, 565-0871 Japan.

Shinobu Inagaki*Last author, Corresponding author
From Group of Neurobiology, Division of Health Sciences, Graduate School of Medicine, Osaka University, Osaka, 565-0871 Japan.

New
The RNA Binding Protein Mex-3B Is Required for IL-33 Induction in the Development of Allergic Airway Inflammation
Cancer & ImmunologyAgo 18 2016Cell Reports

Yusuke Yamazum*First author

Laboratory of Molecular and Genetic Information, Institute for Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.

Tetsu Akiyama*Last author, Corresponding author

Laboratory of Molecular and Genetic Information, Institute for Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.

New
Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
Biochemistry & Molecular BiologyAgo 17 2016Nature Communications

Takashi Ohtsuki*First author, Corresponding author

Department of Biomedical Engineering, Okayama University, 3-1-1 Tsushimanaka, Okayama 700-8530, Japan.

Kazunori Watanabe*Last author

Department of Biomedical Engineering, Okayama University, 3-1-1 Tsushimanaka, Okayama 700-8530, Japan.

New
Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry
Biochemistry & Molecular BiologyAgo 15 2016Nature Chemical Biology

Kei Yamaura*First author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, Japan.

Shigeki Kiyonaka*Corresponding author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, Japan.

Itaru Hamachi*Last author, Corresponding author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, Japan.

New
RpA1 ameliorates symptoms of mutant Ataxin-1 knock-in mice and enhances DNA damage repair
NeuroscienceAgo 11 2016Human Molecular Genetics

Juliana Bosso Taniguchi*First author

Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan

Hitoshi Okazawa*Last author, Corresponding author

Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan

Quiescent center initiation in the Arabidopsis lateral root primordia is dependent on the SCARECROW transcription factor
Plant & Animal ScienceAgo 10 2016Development

Kotaro Tsuboyama*First author, Corresponding author
Department of Biology, Graduate School of Science, Kobe University, Kobe 657-8501, Japan.

Soazig Guyomarc'h*Last author, Corresponding author
5Université de Montpellier, Unité Mixte de Recherche (UMR) Diversité Adaptation et Développement des plantes (DIADE), 34394 Montpellier Cedex 5, France.

New
Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity
Cancer & ImmunologyAgo 09 2016Immunity

Tatsuma Ban*First author

Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.

Go R. Sato*Co-first author

Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.

Tomohiko Tamura*Last author, Corresponding author

Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.

New
A Subtype of Olfactory Bulb Interneurons Is Required for Odor Detection and Discrimination Behaviors
NeuroscienceAgo 03 2016The Journal of Neuroscience

Hiroo Takahashi*First author

Laboratory for Molecular Biology of Neural System, Advanced Medical Research Center, Nara Medical University School of Medicine, Kashihara, Nara 634-8521, Japan.

Yoichi Ogawa*Co-first author

Department of Physiology I, Nara Medical University School of Medicine, Kashihara, Nara 634-8521, Japan.

Akio Tsuboi*Last author, Corresponding author

Laboratory for Molecular Biology of Neural System, Advanced Medical Research Center, Nara Medical University School of Medicine, Kashihara, Nara 634-8521, Japan.

New
In vivo FRET imaging of tumor endothelial cells highlights a role of low PKA activity in vascular hyperpermeability
Cancer & ImmunologyAgo 03 2016Cancer Research

Fumio Yamauchi*First author

Department of Pathology and Biology of Diseases, Kyoto University - Graduate School of Medicine, Yoshida-Konoe-cho, Sakyo-ku, Kyoto, Kyoto, 606-8501, Japan.

Michiyuki Matsuda*Last author, Corresponding author

Department of Pathology and Biology of Diseases, Kyoto University - Graduate School of Medicine, Yoshida-Konoe-cho, Sakyo-ku, Kyoto, Kyoto, 606-8501, Japan.

New
Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling
Developmental BiologyJul 19 2016eLife

Kenji Kamimoto*First author

Laboratory of Cell Growth and Differentiation, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan

Tohru Itoh*Last author, Corresponding author

Laboratory of Cell Growth and Differentiation, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan

New
Liver Progenitors Isolated from Adult Healthy Mouse Liver Efficiently Differentiate to Functional Hepatocytes In Vitro and Repopulate Liver Tissue
Stem CellsJul 13 2016Stem Cells

Naoki Tanimizu*First author

Department of Tissue Development and Regeneration, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Toshihiro Mitaka*Last author, Corresponding author

Department of Tissue Development and Regeneration, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

The intrinsically disordered protein Atg13 mediates supramolecular assembly of autophagy initiation complexes
Cell BiologyJul 11 2016Developmental Cell

Hayashi Yamamoto* First author

Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan

Yuko Fujioka*Co-first author

Institute of Microbial Chemistry (BIKAKEN), Tokyo 141-0021, Japan

Sho W. Suzuki*Co-first author

Frontier Research Center, Tokyo Institute of Technology, Yokohama 226-8503, Japan

Nobuo N. Noda*Corresponding author

Institute of Microbial Chemistry (BIKAKEN), Tokyo 141-0021, Japan

Yoshinori Ohsumi*Last author, Corresponding author

Frontier Research Center, Tokyo Institute of Technology, Yokohama 226-8503, Japan

New
Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator
Cancer & ImmunologyJul 11 2016The Journal of Experimental Medicine

Nobuko Akiyama*First author

Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan.

Taishin Akiyama*Last author, Corresponding author

Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan.

A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling
NeuroscienceJul 05 2016Molecular Psychiatry

M Fujitani*First author, Corresponding author

Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, Suita, Japan

T Yamashita*Last author, Corresponding author

Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, Suita, Japan

The Sam68 nuclear body is composed of two RNase-sensitive substructures joined by the adaptor HNRNPL
Cancer & ImmunologyJul 04 2016The Journal of Cell Biology

Taro Mannen*First author

Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan

Tetsuro Hirose*Last author, Corresponding author

Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan

Developmental Switch in Spike Timing-Dependent Plasticity and Cannabinoid-Dependent Reorganization of the Thalamocortical Projection in the Barrel Cortex
NeuroscienceJun 29 2016The Journal of Neuroscience

Chiaki Itami*First author

Department of Physiology, Faculty of Medicine, Saitama Medical University, Moroyama, Saitama 350-0495, Japan

Fumitaka Kimura*Last author, Corresponding author

Department of Molecular Neuroscience, Osaka University Graduate School of Medicine, Suita 565-0871, Japan 

Memory of cell shape biases stochastic fate decision-making despite mitotic rounding
Cell BiologyJun 28 2016Nature Communications

Takashi Akanuma*First author, Corresponding author

The Thomas N. Sato BioMEC-X Laboratories, Advanced Telecommunications Research Institute International (ATR), Hikaridai 2-2-2, Kyoto 619-0288, Japan

Thomas N. Sato*Last author, Corresponding author

The Thomas N. Sato BioMEC-X Laboratories, Advanced Telecommunications Research Institute International (ATR), Hikaridai 2-2-2, Kyoto 619-0288, Japan

Allosteric activation of membrane-bound glutamate receptors using coordination chemistry within living cells
NeuroscienceJun 27 2016Nature Chemistry

Shigeki Kiyonaka*First author, Corresponding author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan

Itaru Hamachi*Last author, Corresponding author

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan

Micro–adhesion rings surrounding TCR microclusters are essential for T cell activation
Cancer & ImmunologyJun 27 2016The Journal of Experimental Medicine

Akiko Hashimoto-Tane*First author, Corresponding author

Laboratory for Cell Signaling, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan

Takashi Saito*Last author, Corresponding author

Laboratory for Cell Signaling, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan 

p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress
Stem CellsJun 23 2016Cell Stem Cell

Daiki Karigane*First author

Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan

Keiyo Takubo*Last author, Corresponding author

Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan

Autophagosome–lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome
Cell BiologyJun 23 2016The EMBO Journal

Junya Hasegawa*First author

Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences Osaka University, Osaka, Japan

Tamotsu Yoshimori*Last author, Corresponding author

Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences Osaka University, Osaka, Japan

Moss Chloroplasts are Surrounded by a Peptidoglycan Wall Containing D-Amino Acids
Plant & Animal ScienceJun 20 2016The Plant Cell

Takayuki Hirano* First author

Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555, Japan

Hiroyoshi Takano*Last author, Corresponding author

Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555, Japan

Developmental regression of hyaloid vasculature is triggered by neurons
Biomedical ResearchJun 20 2016The Journal of Experimental Medicine

Yusuke Yoshikawa* First author

Department of Vascular Biology, The Sakaguchi Laboratory, School of Medicine, Keio University, Shinjuku-ku, Tokyo 160-8582, Japan

Toru Yamada*Co-first author

Department of Vascular Biology, The Sakaguchi Laboratory, School of Medicine, Keio University, Shinjuku-ku, Tokyo 160-8582, Japan
Yoshiaki Kubota*Last author, Corresponding author

Department of Vascular Biology, The Sakaguchi Laboratory, School of Medicine, Keio University, Shinjuku-ku, Tokyo 160-8582, Japan 

Sperm Affects Head Sensory Neuron in Temperature Tolerance of Caenorhabditis elegans
NeuroscienceJun 16 2016Cell Reports

Satoru Sonoda* First author

Laboratory of Molecular and Cellular Regulation, Faculty of Science and Engineering, and Institute for Integrative Neurobiology, Konan University, 8-9-1 Okamoto, Higashinada-ku, Kobe 658-8501, Japan

Akane Ohta*Corresponding author

Laboratory of Molecular and Cellular Regulation, Faculty of Science and Engineering, and Institute for Integrative Neurobiology, Konan University, 8-9-1 Okamoto, Higashinada-ku, Kobe 658-8501, Japan

Atsushi Kuhara*Last author, Corresponding author

Laboratory of Molecular and Cellular Regulation, Faculty of Science and Engineering, and Institute for Integrative Neurobiology, Konan University, 8-9-1 Okamoto, Higashinada-ku, Kobe 658-8501, Japan

New
Chemical, physical and morphological properties of bacterial biofilms affect survival of encased Campylobacter jejuni F38011 under aerobic stress
MicrobiologyJun 13 2016International Journal of Food Microbiology

Jinsong Feng, Guillaume Lamour, Rui Xue, Mehr Negar Mirvakliki, Savvas G. Hatzikiriakos, Jie Xu, Hongbin Li, ShuoWang, Xiaonan Lu

Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1
Cell BiologyJun 13 2016Nature Communications

Shigeru Matsumura*First author, Corresponding author

Department of Cell Biology, Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan

Fumiko Toyoshima*Last author

Department of Cell Biology, Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan

Phytochrome signaling is mediated by PHYTOCHROME INTERACTING FACTOR in the liverwort Marchantia polymorpha
Plant & Animal ScienceJun 01 2016The Plant Cell

Keisuke Inoue* First author

Graduate School of Biostudies, Kyoto University, Kyoto, 606-8502, Japan

Takayuki Kohchi*Last author, Corresponding author

Graduate School of Biostudies, Kyoto University, Kyoto, 606-8502, Japan

Olfactory receptor for prostaglandin F2α mediates male fish courtship behavior
NeuroscienceMai 30 2016Nature Neuroscience

Yoichi Yabuki* First author

RIKEN Brain Science Institute, Saitama, Japan

Yoshihiro Yoshihara*Last author, Corresponding author

RIKEN Brain Science Institute, Saitama, Japan

Phosphorylation‐dependent Akt–Inversin interaction at the basal body of primary cilia
Cell BiologyMai 23 2016The EMBO Journal

Futoshi Suizu* First author

Division of Cancer Biology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

Masayuki Noguchi*Last author, Corresponding author

Division of Cancer Biology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

Cyclic Nucleotide Control of Microtubule Dynamics for Axon Guidance
NeuroscienceMai 18 2016The Journal of Neuroscience

Hiroki Akiyama* First author

Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan

Hiroyuki Kamiguchi*Last author, Corresponding author
Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan 

Vascular Cell Induction Culture System Using Arabidopsis Leaves (VISUAL) Reveals the Sequential Differentiation of Sieve Element-like Cells
Plant & Animal ScienceMai 18 2016The Plant Cell

Yuki Kondo* First author, Corresponding author

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Hiroo Fukuda*Last author, Corresponding author

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Transient neuronal coactivations embedded in globally propagating waves underlie resting-state functional connectivity
NeuroscienceMai 16 2016PNAS

Teppei Matsui* First author

Department of Physiology, The University of Tokyo School of Medicine, Tokyo 113-0033, Japan

Kenichi Ohki*Last author, Corresponding author

Department of Physiology, The University of Tokyo School of Medicine, Tokyo 113-0033, Japan

F1-ATPase conformational cycle from simultaneous single-molecule FRET and rotation measurements
BioimagingMai 10 2016PNAS

Mitsuhiro Sugawa* First author

Department of Physics, Faculty of Science, Gakushuin University, Tokyo 171-8588, Japan

Takayuki Nishizaka*Last author, Corresponding author

Department of Physics, Faculty of Science, Gakushuin University, Tokyo 171-8588, Japan

Regulation of podocalyxin trafficking by Rab small GTPases in 2D and 3D epithelial cell cultures
Cell BiologyMai 02 2016The Journal of Cell Biology

Paulina S. Mrozowska* First author

Laboratory of Membrane Trafficking Mechanisms, Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi 980-8578, Japan

Mitsunori Fukuda*Last author, Corresponding author

Laboratory of Membrane Trafficking Mechanisms, Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi 980-8578, Japan

New
Potential role of heat-shock protein 70 and interleukin-15 in the pathogenesis of threatened spontaneous abortions
Reproductive BiologyAbr 28 2016American Journal of Reproductive Immunology

Tamara Gulic, Gordana Laskarin, Marin Dominovic, Lana Glavan Gacanin, Emina Babarovic, Herman Haller, Daniel Rukavina

New
Selective expression of transthyretin in subtypes of lung cancer
Cancer & ImmunologyMar 06 2016Journal of Molecular Histology

Shuai Hao, Suozhu Sun, Xueyuan Xiao, Dacheng He, Liyun Liu

New
Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy
Cancer & ImmunologyFev 06 2016American Journal of Reproductive Immunology

Marin Dominovic, Gordana Laskarin, Lana Glavan Gacanin, Herman Haller, Daniel Rukavina

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