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Tacrine is a planar three-ring acridine that was first synthesized by Australian Dr. Adrian Albert in the 1940s during his attempts to develop a new intravenous antiseptic that could be used to aid injured troops fighting in World War II. Though, the drug was never utilized for this purpose and Adrian's efforts were brought to a close when the British discovered penicillin, decades later tacrine would gain a significant amount of attention in the medical field.

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