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Upright Microscopes

Olympus upright microscopes offer high-quality imaging for life science and clinical research. With world-class Olympus microscope optics, you can expect high-resolution, high-contrast microscopy imagery for viewing, insight, and analysis.

Ergonomic, flexible, and easy to use, the highly versatile Olympus upright microscope range provides precise operations and fast, efficient image capture with true color LED illumination. There are a range of upright microscopes available to suit a variety of users and application needs, from automated upright fluorescence microscopes for complex multidimensional experiments to fixed stage microscopes, ideally suited to brain slice and in vivo electrophysiology. For clinical research, our upright microscopes offer accurate color reproduction for cytology and pathology research as well as outstanding image quality for routine clinical lab testing.

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Upright Microscopes

Automated Fluorescence Microscope


  • Fully motorized system allows automation of complex multidimensional experiments
  • Accurate motorized Z-drive
  • High stability due to fixed stage design
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Semi-Motorized Fluorescence Microscope


  • High-luminosity True Color LED illumination
  • Modular concept enables individual components to be motorized
  • Easily acquire multi-color fluorescence images
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Manual System Microscope


  • True Color LED illumination
  • Light intensity manager
  • Allows easy contrast management
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Clinical Microscope


  • Unrivalled ergonomic design
  • World´s first tilting, telescopic, lifting tube
  • Ultra-low fixed stage
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Biological Microscope


  • Ergonomic design
  • Ideal for versatile application
  • Long lifetime LED illumination

* Optional single line LED light source for fluorescence (peak excitation wavelength 470 nm only)

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Biological Microscope


  • Ergonomic design
  • Long lifetime LED illumination
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Biological Microscope


  • Diverse, User-friendly design
  • Outstanding optical performance
  • Long lifetime LED illumination
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Polarizing Microscope


  • A full-featured polarizing microscope
  • Sharper images with UIS2 optics
  • Ergonomically designed for research use
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Fixed Stage Microscope


  • Ideally suited to brain-slice and in-vivo electrophysiology
  • Water immersion optics designed for electrophysiological applications
  • Stability and reliability due to fixed stage concept
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Fixed-Stage Post Microscope

OpenStand Microscope Frame

  • Modular and flexible electrophysiology solution
  • Configurable with Olympus optics and Prior Scientific accessories
  • Motorized Z accommodates a wide specimen range
Asbestos Measurement Microscope


  • Suitable for various types of asbestos observation
  • Easy to measure/record with digital cameras
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Upright Microscope FAQs

What are the applications of upright microscopes?

Upright microscopes are used in life sciences and cell biology for phase contrast, brightfield, darkfield, differential interference contrast (DIC), polarization, or fluorescence microscopy of slide samples. Upright microscopes can also be used in the microscopy of fixed cells or tissue samples.

How does an upright microscope work?

In an upright microscope, the light source and condenser are located beneath the stage and, therefore, the specimen. Light is transmitted through the sample from below, and it can then be viewed from above with an ocular lens.

While with an inverted microscope, gravity naturally causes cells to sink to the bottom and adhere to the coverslip, when using an upright microscope for cell biology applications, the samples are instead squeezed between the coverslip and a slide. This allows the sample to be successfully viewed and analyzed with the upright microscope from above.

Upright Microscope Resource Videos

Olympus BX3 Upright Microscope Product Introduction

This video takes a closer look at the Olympus BX3 upright microscope, offering an automatic light intensity manager, user-friendly controls, and the lowest stage on the market.

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