Inverted Microscopes

Inverted microscopes are a valuable piece of equipment for laboratory cell analysis. Using advanced imaging techniques, Olympus inverted microscopes allow you to observe cells for life science research through the use of fluorescence microscopy and brightfield microscopy.  From routine inverted microscopes to super resolution, compound, TIRF imaging, and confocal microscopy solutions, the vast range of inverted microscopes from Olympus allow you to expand your vision, with ergonomic designs offering accurate, precise imaging solutions. Get in Touch

Loading the player… source Introduction to IXplore Inverted Microscope Systems Related Videos

Inverted Research Microscopes

Compound Microscope System

IXplore Standard

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• Repeatability and accuracy for standard imaging tasks
• Benefit from the same optical capabilities found in high-end IXplore systems
• Easily upgrade to encoded functionality to boost reproducibility of experiments
• Obtain high quality images, even with standard cell culture vessels

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Automated Microscope System

IXplore Pro

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• Automated multi-dimensional observation with easy experiment set up
• Boost your statistics with multi-well plate screening
• Acquire fluorescence panoramic images of large samples, such as brain slices
• Increase resolution and create optical sections with deconvolution
• Create 3D optical sections and enhance resolution with TruSight

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Live Cell Imaging Microscope System

IXplore Live

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• Utilize the Olympus real time controller for physiologically relevant data with minimal cell disturbance
• Maintain cell viability while imaging with various environmental control options
• Maintain focus accurately and reliably in time-lapse experiments with TruFocus
• Discover the real morphology of your cells with Olympus silicone immersion optics

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TIRF Imaging Microscope System

IXplore TIRF

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• Excellent simultaneous multi-color TIRF for investigation of membrane dynamics and single molecule detection 
• Exact colocalization of up to four markers thanks to individual penetration depth control
• Take advantage of Olympus’ remarkable TIRF objective with the world's highest NA of 1.7* (*As of July 25, 2017. According to Olympus research)
• Intuitive set-up of complex experiments with Graphical Experiment Manager (GEM)

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Confocal Imaging Microscope System

IXplore Spin

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• Rapid and high-resolution confocal imaging with a spinning disk system
• 3D confocal time-lapse imaging of live cells with less phototoxicity and bleaching
• Precise 3D imaging with improved light collection using X Line objectives
• Upgrade to the IXplore SpinSR super resolution system depending on your research progress and/or budget

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Super Resolution Microscope System

IXplore SpinSR

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• Super resolution down to 120 nm XY resolution
• Prolonged cell viability in confocal time-lapse imaging due to less phototoxicity and bleaching
• Switch between widefield, confocal and super-resolution with one click
• Accurate 3D reconstruction with the world’s first plan apochromat objectives with a numerical aperture (NA) of 1.5^{*1
  *1 As of November 2018. According to Olympus research.}

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Compact Cell Culture Microscope

CKX53

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• Pre-centered phase contrast
• Inversion contrast (IVC) technique provides clear three-dimensional views.
• Fluorescence with 3 positions slider
• Ideal for cell/tissue culture microscope

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Inverted Research Microscope FAQs

How does an inverted microscope work?

An inverted microscope is similar in nature to a compound microscope. However, the components are positioned in inverted order—thus the name “inverted” microscope. While with a compound microscope, you can expect to find the light source and condenser lens beneath the stage and specimen, in an inverted microscope, the condenser lens and light source are placed above the specimen.
This component positioning means that in an inverted microscope, light is directed from above and the image is then viewed from below, making this type of microscope suitable for viewing culture vessels, including glass flasks or petri dishes.

How to use an inverted microscope

Inverted research microscopes use magnification for precise cell viewing and analysis. An inverted microscope uses a fixed stage, with an objective lens for magnification that can be moved along a vertical axis to adjust the focus of a specimen or to allow the specimen to be brought closer or moved further away. Once focused, the user then observes the specimen through the inverted microscope’s ocular lens, or via a screen if using the microscope together with a video camera.

Inverted Microscope Resource Videos

Silicone Oil Immersion Objectives for Live Cell Imaging When looking at live cells, using the right objectives will enable you to see clearly. This video looks at the ways in which silicone oil immersion objectives achieve precise and higher-resolution imagery during cell and tissue observation.	Loading the player… source Silicone Oil Immersion Objectives: For Live Cell Imaging Related Videos