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BLADE-ON-PETIOLE genes temporally and developmentally regulate the sheath to blade ratio of rice leaves
Plant & Animal ScienceФев 06 2019Nature Communications

Taiyo Toriba, Hiroki Tokunaga, Toshihide Shiga, Fanyu Nie, Satoshi Naramoto, Eriko Honda, Keisuke Tanaka, Teruaki Taji, Jun-Ichi Itoh & Junko Kyozuka

Cold acclimation via the KQT-2 potassium channel is modulated by oxygen in Caenorhabditis elegans
NeuroscienceФев 06 2019Science Advances

Misaki Okahata, Aguan D. Wei, Akane Ohta, Atsushi Kuhara

Zinc regulates ERp44-dependent protein quality control in the early secretory pathway
Biochemistry & Molecular BiologyФев 05 2019Nature Communications

Satoshi Watanabe, Yuta Amagai, Sara Sannino, Tiziana Tempio, Tiziana Anelli, Manami Harayama, Shoji Masui, Ilaria Sorrentino, Momo Yamada, Roberto Sitia & Kenji Inaba

Inhibition of T cell activation and function by the CIN85 adaptor protein
Cancer & ImmunologyФев 05 2019Science Signaling

Mei Suen Kong, Akiko Hashimoto-Tane, Yusuke Kawashima, Machie Sakuma, Tadashi Yokosuka, kohei Kometani, Reiko Onishi, Nick Carpino, Osamu Ohara, Tomohiro Kurosaki, Kia Kien Phua and Takashi Saito

Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure
Cancer & ImmunologyФев 04 2019PNAS

Takaharu Sakuragi, Hidetaka Kosako, and Shigekazu Nagata

Rab10 regulates tubular endosome formation through KIF13A/B motors
Cell BiologyЯнв 30 2019Journal of Cell Science

Kan Etoh, Mitsunori Fukuda

ELKS/Voltage-Dependent Ca2+ Channel-β Subunit Module Regulates Polarized Ca2+ Influx in Pancreatic β Cells
Cell BiologyЯнв 29 2019Cell Reports

Mica Ohara-Imaizumi,Kyota Aoyagi,Hajime Yamauchi,Masashi Yoshida,Masayuki X. Mori,Yamato Hida,Ha Nam Tran,Masamichi Ohkura,Manabu Abe,Yoshihiro Akimoto,Yoko Nakamichi,Chiyono Nishiwaki,Hayato Kawakami,Kazuo Hara,Kenji Sakimura,Shinya Nagamatsu,Yasuo Mori,Junichi Nakai,Masafumi Kakei,Toshihisa Ohtsuka

A Rho-actin signaling pathway shapes cell wall boundaries in Arabidopsis xylem vessels
Plant & Animal ScienceЯнв 28 2019Nature Communications

Yuki Sugiyama, Yoshinobu Nagashima, Mayumi Wakazaki, Mayuko Sato, Kiminori Toyooka, Hiroo Fukuda & Yoshihisa Oda

Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis
Cancer & ImmunologyЯнв 28 2019The Journal of Immunology

Nayuta Saito, Jun Araya, Saburo Ito, Kazuya Tsubouchi, Shunsuke Minagawa, Hiromichi Hara, Akihiko Ito, Takayuki Nakano, Yusuke Hosaka, Akihiro Ichikawa, Tsukasa Kadota, Masahiro Yoshida, Yu Fujita, Hirofumi Utsumi, Yusuke Kurita, Kenji Kobayashi, Mitsuo Hashimoto, Hiroshi Wakui, Takanori Numata, Yumi Kaneko, Hisatoshi Asano, Makoto Odaka, Takashi Ohtsuka, Toshiaki Morikawa, Katsutoshi Nakayama and Kazuyoshi Kuwano

Neuropilin-1-mediated pruning of corticospinal tract fibers is required for motor recovery after spinal cord injury
NeuroscienceЯнв 25 2019Cell Death & Disease

Toru Nakanishi, Yuki Fujita & Toshihide Yamashita

Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas
Cancer & ImmunologyЯнв 25 2019Leukemia

Keisuke Kataoka, Hiroaki Miyoshi, Seiji Sakata, Akito Dobashi, Lucile Couronné, Yasunori Kogure, Yasuharu Sato, Kenji Nishida, Yuka Gion, Yuichi Shiraishi, Hiroko Tanaka, Kenichi Chiba, Yosaku Watatani, Nobuyuki Kakiuchi, Yusuke Shiozawa, Tetsuichi Yoshizato, Kenichi Yoshida, Hideki Makishima, Masashi Sanada, Masahiro Onozawa, Takanori Teshima, Yumiko Yoshiki, Tadao Ishida, Kenshi Suzuki, Kazuyuki Shimada, Akihiro Tomita, Motohiro Kato, Yasunori Ota, Koji Izutsu, Ayako Demachi-Okamura, Yoshiki Akatsuka, Satoru Miyano, Tadashi Yoshino, Philippe Gaulard, Olivier Hermine, Kengo Takeuchi, Koichi Ohshima & Seishi Ogawa

Abundance of non-conservative microplastics in the upper ocean from 1957 to 2066
Biological oceanographyЯнв 24 2019Nature Communications

Atsuhiko Isobe, Shinsuke Iwasaki, Keiichi Uchida & Tadashi Tokai

A critical role of Arf6 in the response of commissural axons to Slit
Developmental BiologyЯнв 23 2019Development

Mariko Kinoshita-Kawada, Hiroshi Hasegawa, Tsunaki Hongu, Shigeru Yanagi, Yasunori Kanaho, Ichiro Masai, Takayasu Mishima, Xiaoping Chen, Yoshio Tsuboi, Yi Rao, Junichi Yuasa-Kawada, Jane Y. Wu

GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites
Cancer & ImmunologyЯнв 23 2019Nature

Naoki Morita, Eiji Umemoto, Setsuko Fujita, Akio Hayashi, Junichi Kikuta, Ikuo Kimura, Takeshi Haneda, Toshio Imai, Asuka Inoue, Hitomi Mimuro, Yuichi Maeda, Hisako Kayama, Ryu Okumura, Junken Aoki, Nobuhiko Okada, Toshiyuki Kida, Masaru Ishii, Ryusuke Nabeshima & Kiyoshi Takeda

Nrf2 Suppresses Allergic Lung Inflammation by Attenuating the Type 2 Innate Lymphoid Cell Response
Cancer & ImmunologyЯнв 23 2019The Journal of Immunology

Ryuichi Nagashima, Hitomi Kosai, Masahiro Masuo, Keiko Izumiyama, Taketo Noshikawaji, Motoko Morimoto, Satoru Kumaki, Yasunari Miyazaki, Hozumi Motohashi, Masayuki Yamamoto and Nobuyuki Tanaka

Large Timescale Interrogation of Neuronal Function by Fiberless Optogenetics Using Lanthanide Micro-particles
NeuroscienceЯнв 22 2019Cell Reports

Toh Miyazaki, Srikanta Chowdhury, Takayuki Yamashita, Takanori Matsubara, Hiromu Yawo, Hideya Yuasa and Akihiro Yamanaka

EphA2 phosphorylation at Ser897 by the Cdk1/MEK/ERK/RSK pathway regulates M-phase progression via maintenance of cortical rigidity
Biochemistry & Molecular BiologyЯнв 22 2019The FASEB Journal

Yuichiro Kaibori, Youhei Saito, and Yuji Nakayama

How Do Ice Crystals Grow inside Quasiliquid Layers?
Biological oceanographyЯнв 18 2019Physical Review Letters

Ken-ichiro Murata, Ken Nagashima, and Gen Sazaki

A complex between phosphatidylinositol 4 kinase IIα and integrin α3β1 is required for N-glycan sialylation in cancer cells
Biochemistry & Molecular BiologyЯнв 18 2019The Journal of Biological Chemistry

Tomoya Isaji, Sanghun Im, Akihiko Kameyama, Yuqin Wang, Tomohiko Fukuda, and Jianguo Gu

The phytosphingosine-CD300b interaction promotes zymosan-induced, nitric oxide–dependent neutrophil recruitment
Cancer & ImmunologyЯнв 16 2019Science Signaling

MARIKO TAKAHASHI, KUMI IZAWA, MAKOTO URAI, YOSHINORI YAMANISHI, AKIE MAEHARA, MASAMICHI ISOBE, TOSHIHIRO MATSUKAWA, AYAKO KAITANI, AYAKO TAKAMORI, SHINO UCHIDA, HIROMICHI YAMADA, MASAKAZU NAGAMINE, TOMOAKI ANDO, TOSHIAKI SHIMIZU, HIDEOKI OGAWA, KO OKUMURA, YUKI KINJO, TOSHIO KITAMURA, JIRO KITAURA

Comparative Evaluation of Genetically Encoded Voltage Indicators
NeuroscienceЯнв 15 2019Cell Reports

Yuki Bando, Masayuki Sakamoto, Samuel Kim, Inbal Ayzenshtat, and Rafael Yuste

Membrane-associated RING-CH (MARCH) 1 and 2 are MARCH family members that inhibit HIV-1 infection
Biochemistry & Molecular BiologyЯнв 11 2019The Journal of Biological Chemistry

Yanzhao Zhang, Takuya Tada, Seiya Ozono, Weitong Yao, Michiko Tanaka, Shoji Yamaoka, Satoshi Kishigami, Hideaki Fujita, and Kenzo Tokunaga

Liquid- and solid-like RNA granules form through specific scaffold proteins and combine into biphasic granules
Biochemistry & Molecular BiologyЯнв 03 2019The Journal of Biological Chemistry

Nobuyuki Shiina

Transcriptional regulators involved in responses to volatile organic compounds in plants
Biochemistry & Molecular BiologyДек 28 2018The Journal of Biological Chemistry

Ayumi Nagashima, Takumi Higaki, Takao Koeduka, Ken Ishigami, Satoko Hosokawa, Hidenori Watanabe, Kenji Matsui, Seiichiro Hasezawa, and Kazushige Touhara

Conserved fungal effector suppresses PAMP-triggered immunity by targeting plant immune kinases
Plant & Animal ScienceДек 24 2018PNAS

Hiroki Irieda, Yoshihiro Inoue, Masashi Mori, Kohji Yamada, Yuu Oshikawa, Hiromasa Saitoh, Aiko Uemura, Ryohei Terauchi, Saeko Kitakura, Ayumi Kosaka, Suthitar Singkaravanit-Ogawa, and Yoshitaka Takano

An amphipathic helix of vinexin α is necessary for substrate stiffness-dependent conformational change in vinculin
Cell BiologyДек 21 2018Journal of Cell Science

Naoya Hino, Takafumi Ichikawa, Yasuhisa Kimura, Michiyuki Matsuda, Kazumitsu Ueda, Noriyuki Kioka

Synthetic mammalian pattern formation driven by differential diffusivity of Nodal and Lefty
Cell BiologyДек 21 2018Nature Communications

Ryoji Sekine, Tatsuo Shibata & Miki Ebisuya

Behavioral role of the reciprocal inhibition between a pair of Mauthner cells during fast escapes in zebrafish
NeuroscienceДек 21 2018The Journal of Neuroscience

Takashi Shimazaki, Masashi Tanimoto, Yoichi Oda and Shin-ichi Higashijima

Lateral Inhibition by a Peptide Hormone-Receptor Cascade during Arabidopsis Lateral Root Founder Cell Formation
Developmental BiologyДек 20 2018Developmental Cell

Koichi Toyokura, Tatsuaki Goh, Hidefumi Shinohara, Akinori Shinoda, Yuki Kondo, Yoshie Okamoto, Takeo Uehara, Koichi Fujimoto, Yoko Okushima, Yoshifumi Ikeyama, Keiji Nakajima, Tetsuro Mimura, Masao Tasaka, Yoshikatsu Matsubayashi, and Hidehiro Fukaki

Competition for mitogens regulates spermatogenic stem cell homeostasis in an open niche
Stem CellsДек 20 2018Cell Stem Cell

Yu Kitadate, David J. Jörg, Moe Tokue, Ayumi Maruyama, Rie Ichikawa, Soken Tsuchiya, Eri Segi-Nishida, Toshinori Nakagawa, Aya Uchida, Chiharu Kimura-Yoshida, Seiya Mizuno, Fumihiro Sugiyama, Takuya Azami, Masatsugu Ema, Chiyo Noda, Satoru Kobayashi, Isao Matsuo, Yoshiakira Kanai, Takashi Nagasawa, Yukihiko Sugimoto, Satoru Takahashi, Benjamin D. Simons, Shosei Yoshida

Three-dimensional cell geometry controls excitable membrane signaling in Dictyostelium cells
Cell BiologyДек 19 2018Biophysical Journal

Marcel Hörning, Tatsuo Shibata

New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration
NeuroscienceДек 12 2018Science Advances

N. Kaneko, V. Herranz-Pérez, T. Otsuka, H. Sano, N. Ohno, T. Omata, H. B. Nguyen, T. Q. Thai, A. Nambu, Y. Kawaguchi, J. M. García-Verdugo, K. Sawamoto

Proteasomal degradation of BRAHMA promotes Boron tolerance in Arabidopsis
Plant & Animal ScienceДек 11 2018Nature Communications

Takuya Sakamoto, Yayoi Tsujimoto-Inui, Naoyuki Sotta, Takeshi Hirakawa, Tomoko M. Matsunaga, Yoichiro Fukao, Sachihiro Matsunaga & Toru Fujiwara

Transcription factor DUO1 generated by neo-functionalization is associated with evolution of sperm differentiation in plants
Plant & Animal ScienceДек 11 2018Nature Communications

Asuka Higo, Tomokazu Kawashima, Michael Borg, Mingmin Zhao, Irene López-Vidriero, Hidetoshi Sakayama, Sean A. Montgomery, Hiroyuki Sekimoto, Dieter Hackenberg, Masaki Shimamura, Tomoaki Nishiyama, Keiko Sakakibara, Yuki Tomita, Taisuke Togawa, Kan Kunimoto, Akihisa Osakabe, Yutaka Suzuki, Katsuyuki T. Yamato, Kimitsune Ishizaki, Ryuichi Nishihama, Takayuki Kohchi, José M. Franco-Zorrilla, David Twell, Frédéric Berger & Takashi Araki

Chromatin-mediated feed-forward auin biosynthesis in floral meristem determinacy
Plant & Animal ScienceДек 11 2018Nature Communications

Nobutoshi Yamaguchi, Jiangbo Huang, Yoshitaka Tatsumi, Masato Abe, Shigeo S. Sugano, Mikiko Kojima, Yumiko Takebayashi, Takatoshi Kiba, Ryusuke Yokoyama, Kazuhiko Nishitani, Hitoshi Sakakibara, and Toshiro Ito

GABA-induced intracellular Mg2+ mobilization integrates and coordinates cellular information for maturation of neural network
Cell BiologyДек 06 2018Current Biology

Ryu Yamanaka, Yutaka Shindo, Kohji Hotta, Koji Suzuki, Kotaro Oka

Inner ear development in cyclostomes and evolution of the vertebrate semicircular canals
Developmental BiologyДек 05 2018Nature

Shinnosuke Higuchi, Fumiaki Sugahara, Juan Pascual-Anaya, Wataru Takagi, Yasuhiro Oisi and Shigeru Kuratani

The CLE9/10 secretory peptide regulates stomatal and vascular development through distinct receptors
Plant & Animal ScienceДек 05 2018Nature Plants

Pingping Qian, Wen Song, Toshiya Yokoo, Ayako Minobe, Guodong Wang, Takashi Ishida, Shinichiro Sawa, Jijie Chai & Tatsuo Kakimoto 

Long-Term Memory Engram Cells Are Established by c-Fos/CREB Transcriptional Cycling
NeuroscienceДек 04 2018Cell Reports

Tomoyuki Miyashita, Emi Kikuchi, Junjiro Horiuchi, Minoru Saitoe

Supramammillary Nucleus Afferents to the Dentate Gyrus Co-release Glutamate and GABA and Potentiate Granule Cell Output
NeuroscienceДек 04 2018Cell Reports

Yuki Hashimotodani, Fuyuki Karube, Yuchio Yanagawa, Fumino Fujiyama, Masanobu Kano

A Pretreatment‐Free, Polymer‐Based Platform Prepared by Molecular Imprinting and Post‐Imprinting Modifications for Sensing Intact Exosomes
BioimagingДек 04 2018Angewandte Chemie International Edition

Kisho Mori, Mitsuhiro Hirase, Takahiro Morishige, Dr. Eri Takano, Dr. Hirobumi Sunayama, Dr. Yukiya Kitayama, Dr. Sachiko Inubushi, Prof. Dr. Ryohei Sasaki, Prof. Dr. Masakazu Yashiro, Prof. Dr. Toshifumi Takeuchi

Cell surface CD63 increased by up-regulated polylactosamine modification sensitizes human melanoma cells to the BRAF inhibitor PLX4032
Biochemistry & Molecular BiologyДек 03 2018The FASEB Journal

Kohya Kudo, Atsuko Yoneda, Daiki Sakiyama, Kai Kojima, Takeki Miyaji, Miku Yamazaki, Saori Yaita, Takuya Hyodo, Reiko Satow, and Kiyoko Fukami

Constitutive boost of a K+ channel via inherent bilayer tension and a unique tension-dependent modality
Cell BiologyДек 03 2018PNAS

Masayuki Iwamoto and Shigetoshi Oiki

Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition
Biomedical ResearchНоя 30 2018PLoS Genetics

Nao Nagai, Hiroto Ohguchi, Ryo Nakaki, Yoshihiro Matsumura, Yasuharu Kanki, Juro Sakai, Hiroyuki Aburatani, Takashi Minami

Drebrin-like (Dbnl) controls neuronal migration via regulating N-cadherin expression in the developing cerebral cortex
NeuroscienceНоя 30 2018The Journal of Neuroscience

Seika Inoue, Kanehiro Hayashi, Kyota Fujita, Kazuhiko Tagawa, Hitoshi Okazawa, Ken-ichiro Kubo and Kazunori Nakajima

Fiber-associated spirochetes are major agents of hemicellulose degradation in the hindgut of wood-feeding higher termites
Plant & Animal ScienceНоя 30 2018PNAS

Gaku Tokuda, Aram Mikaelyan, Chiho Fukui, Yu Matsuura, Hirofumi Watanabe, Masahiro Fujishima, and Andreas Brune

Kmt2b conveys monovalent and bivalent H3K4me3 in mouse spermatogonial stem cells at germline and embryonic promoters
Developmental BiologyНоя 30 2018Development

Shin-ichi Tomizawa, Yuki Kobayashi, Takayuki Shirakawa, Kumiko Watanabe, Keita Mizoguchi, Ikue Hoshi, Kuniko Nakajima, Jun Nakabayashi, Sukhdeep Singh, Andreas Dahl, Dimitra Alexopoulou, Masahide Seki, Yutaka Suzuki, Hélène Royo, Antoine H. F. M. Peters, Konstantinos Anastassiadis, A. Francis Stewart, Kazuyuki Ohbo

Apolipoprotein E is an HIV-1-inducible inhibitor of viral production and infectivity in macrophages
MicrobiologyНоя 29 2018PLoS Pathogens

Rokeya Siddiqui, Shinya Suzu, Mikinori Ueno, Hesham Nasser, Ryota Koba, Farzana Bhuyan, Osamu Noyori, Sofiane Hamidi, Guojun Sheng, Mariko Yasuda-Inoue, Takayuki Hishiki, Sayaka Sukegawa, Eri Miyagi, Klaus Strebel, Shuzo Matsushita, Kunitada Shimotohno, Yasuo Ariumi

Heat shock–induced mitotic arrest requires heat shock protein 105 for the activation of spindle assembly checkpoint
Biochemistry & Molecular BiologyНоя 29 2018The FASEB Journal

Ayana Kakihana, Yui Oto, Youhei Saito, and Yuji Nakayama

The male gamete membrane protein DMP9/DAU2 is required for double fertilization in flowering plants
Developmental BiologyНоя 29 2018Development

Taro Takahashi, Toshiyuki Mori, Kenji Ueda, Lixy Yamada, Shiori Nagahara, Tetsuya Higashiyama, Hitoshi Sawada, Tomoko Igawa

[Na+] increases in body fluids sensed by central Nax induce sympathetically-mediated blood pressure elevations via H+-dependent activation of ASIC1a
NeuroscienceНоя 29 2018Neuron

Kengo Nomura, Takeshi Y. Hiyama, Hiraki Sakuta, Takashi Matsuda, Chia-Hao Lin, Kenta Kobayashi, Kazuto Kobayashi, Tomoyuki Kuwaki, Kunihiko Takahashi, Shigeyuki Matsui, and Masaharu Noda

The hydrophobic nature of a novel membrane interface regulates the enzyme activity of a voltage-sensing phosphatase
Cell BiologyНоя 28 2018eLife

Akira Kawanabe, Masaki Hashimoto, Manami Nishizawa, Kazuhisa Nishizawa, Hirotaka Narita, Tomoko Yonezawa, Yuka Jinno, Souhei Sakata, Atsushi Nakagawa, Yasushi Okamura

Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-base DNA Aptamers Targeting Cancer Cells
Biomedical ResearchНоя 28 2018Molecular Therapy – Nucleic Acids

Kazunobu Futami, Michiko Kimoto, Yun Wei, Shermane Lim, Ichiro Hirao

Cooperative actions of Tbc1d1 and AS160/Tbc1d4 in GLUT4 trafficking activities
Biochemistry & Molecular BiologyНоя 27 2018The Journal of Biological Chemistry

Hiroyasu Hatakeyama, Taisuke Morino, Takuya Ishii, and Makoto Kanzaki

Cascade Reaction in Human Live Tissue Allows Clinically Applicable Diagnosis of Breast Cancer Morphology
Biochemistry & Molecular BiologyНоя 27 2018Advanced Science

Tomonori Tanei, Ambara R. Pradipta, Koji Morimoto, Motoko Fujii, Mayumi Arata, Akihiro Ito, Minoru Yoshida, Elena Saigitbatalova, Almira Kurbangalieva, Jun-ichiro Ikeda, Eiichi Morii, Shinzaburo Noguchi and Katsunori Tanaka

Ipsilateral-dominant control of limb movements in rodent posterior parietal cortex
NeuroscienceНоя 26 2018The Journal of Neuroscience

Shogo Soma, Junichi Yoshida, Shigeki Kato, Yukari Takahashi, Satoshi Nonomura, Yae K. Sugimura, Alain Ríos, Masanori Kawabata, Kazuto Kobayashi, Fusao Kato, Yutaka Sakai and Yoshikazu Isomura

Strain-Triggered Mechanical Feedback in Self-Organizing Optic Cup Morphogenesis
Stem CellsНоя 21 2018Science Advances

S. Okuda, N. Takata, Y. Hasegawa, M. Kawada, Y. Inoue, T. Adachi, Y. Sasai, M. Eiraku

Convection-induced biased distribution of actin probes in live cells
Biochemistry & Molecular BiologyНоя 21 2018Biophysical Journal

Sawako Yamashiro, Daisuke Taniguchi, Soichiro Tanaka, Tai Kiuchi, Dimitrios Vavylonis, Naoki Watanabe

Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity
Biomedical ResearchНоя 19 2018Nature Communications

Tetsuya Kubota, Mariko Inoue, Naoto Kubota, Iseki Takamoto, Tomoka Mineyama, Kaito Iwayama, Kumpei Tokuyama, Masao Moroi, Kohjiro Ueki, Toshimasa Yamauchi & Takashi Kadowaki

Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection
MicrobiologyНоя 19 2018Nature Microbiology

Seiki Fujiwara, Midori Hoshizaki, Yu Ichida, Dennis Lex, Etsushi Kuroda, Ken J. Ishii, Shigeyuki Magi, Mariko Okada, Hiroyuki Takao, Masahiro Gandou, Hirotaka Imai, Ryujiro Hara, Herbert Herzog, Akihiko Yoshimura, Hitoshi Okamura, Josef M. Penninger, Arthur S. Slutsky, Stefan Uhlig, Keiji Kuba & Yumiko Imai

Synthetic RNA-based logic computation in mammalian cells
Biochemistry & Molecular BiologyНоя 19 2018Nature Communications

Satoshi Matsuura, Hiroki Ono, Shunsuke Kawasaki, Yi Kuang, Yoshihiko Fujita & Hirohide Saito

Single-nanoparticle tracking with angstrom localization precision and microsecond time resolution
Biochemistry & Molecular BiologyНоя 16 2018Biophysical Journal

Jun Ando, Akihiko Nakamura, Akasit Visootsat, Mayuko Yamamoto, Chihong Song, Kazuyoshi Murata, Ryota Iino

Structural Basis of H+-Dependent Conformational Change in a Bacterial MATE Transporter
Biochemistry & Molecular BiologyНоя 15 2018Structure

Tsukasa Kusakizako, Derek P. Claxton, Yoshiki Tanaka, Andrés D. Maturana, Teruo Kuroda, Ryuichiro Ishitani, Hassane S. Mchaourab, Osamu Nureki

Aberrant IP3 receptor activities revealed by comprehensive analysis of pathological mutations causing spinocerebellar ataxia 29
Cell BiologyНоя 14 2018PNAS

Hideaki Ando, Matsumi Hirose, and Katsuhiko Mikoshiba

Impact of modular organization on dynamical richness in cortical networks
Biochemistry & Molecular BiologyНоя 14 2018Science Advances

Hideaki Yamamoto, Satoshi Moriya, Katsuya Ide, Takeshi Hayakawa, Hisanao Akima, Shigeo Sato, Shigeru Kubota, Takashi Tanii, Michio Niwano, Sara Teller, Jordi Soriano, Ayumi Hirano-Iwata 

Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission–associated myocardial senescence
Biochemistry & Molecular BiologyНоя 13 2018Science Signaling

Akiyuki Nishimura, Tsukasa Shimauchi, Tomohiro Tanaka, Kakeru Shimoda, Takashi Toyama, Naoyuki Kitajima, Tatsuya Ishikawa, Naoya Shindo, Takuro Numaga-Tomita, Satoshi Yasuda, Yoji Sato, Koichiro Kuwahara, Yoshito Kumagai, Takaaki Akaike, Tomomi Ide, Akio Ojida, Yasuo Mori, Motohiro Nishida

Organelle DNA degradation contributes to the efficient use of phosphate in seed plants
Plant & Animal ScienceНоя 12 2018Nature Plants

Tsuneaki Takami, Norikazu Ohnishi, Yuko Kurita, Shoko Iwamura, Miwa Ohnishi, Makoto Kusaba, Tetsuro Mimura & Wataru Sakamoto

Simultaneous Observation of Kinesin-Driven Microtubule Motility and Binding of Adenosine Triphosphate Using Linear Zero-Mode Waveguides
Biochemistry & Molecular BiologyНоя 12 2018ACS Nano

Kazuya Fujimoto, Yuki Morita, Ryota Iino, Michio Tomishige, Hirofumi Shintaku, Hidetoshi Kotera, and Ryuji Yokokawa

NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene Rnf183 under hypertonic conditions in inner-medullary collecting duct cells
Biochemistry & Molecular BiologyНоя 09 2018The Journal of Biological Chemistry

Yujiro Maeoka, Yan Wu, Takumi Okamoto, Soshi Kanemoto, Xiao Peng Guo, Atsushi Saito, Rie Asada, Koji Matsuhisa, Takao Masaki, Kazunori Imaizumi, and Masayuki Kaneko

Ventricular-subventricular zone fractones are speckled basement membranes that function as a neural stem cell niche
Cell BiologyНоя 09 2018Molecular Biology of the Cell

Yuya Sato, Daiji Kiyozumi, Sugiko Futaki, Itsuko Nakano, Chisei Shimono, Naoko Kaneko, Masahito Ikawa, Masaru Okabe, Kazunobu Sawamoto, and Kiyotoshi Sekiguchi

The nucleosome remodeling and deacetylase complex protein CHD4 regulates neural differentiation of mouse embryonic stem cells by down-regulating p53
Biochemistry & Molecular BiologyНоя 08 2018The Journal of Biological Chemistry

Akira Hirota, May Nakajima-Koyama, Yuhei Ashida, and Eisuke Nishida

The Ubiquitin-Proteasome System Is Indispensable for the Maintenance of Muscle Stem Cells
Stem CellsНоя 08 2018Stem Cell Reports

Yasuo Kitajima, Naoki Suzuki, Aki Nunomiya, Shion Osana, Kiyoshi Yoshioka, Yoshitaka Tashiro, Ryosuke Takahashi, Yusuke Ono, Masashi Aoki, Ryoichi Nagatomi

Placenta Specific 8 Suppresses IL-18 Production through Regulation of Autophagy and Is Associated with Adult Still Disease
Cancer & ImmunologyНоя 07 2018The Journal of Immunology

Seiji Segawa, Yuya Kondo, Yuji Nakai, Akira Iizuka, Shunta Kaneko, Masahiro Yokosawa, Kotona Furuyama, Hiroto Tsuboi, Daisuke Goto, Isao Matsumoto and Takayuki Sumida

Parallel signaling pathways regulate excitable dynamics differently to mediate pseudopod formation during eukaryotic chemotaxis
Cell BiologyНоя 07 2018Journal of Cell Science

Yuki Tanabe, Yoichiro Kamimura, Masahiro Ueda

ANGUSTIFOLIA Regulates Actin Filament Alignment for Nuclear Positioning in Leaves
Plant & Animal ScienceНоя 07 2018Plant Physiology

Kosei Iwabuchi, Haruna Ohnishi, Kentaro Tamura, Yoichiro Fukao, Tomoaki Furuya, Koro Hattori, Hirokazu Tsukaya, Ikuko Hara-Nishimura

Structural basis of Gip1 for cytosolic sequestration of G protein in wide-range chemotaxis
Biochemistry & Molecular BiologyНоя 06 2018Nature Communications

Takero Miyagawa, Hiroyasu Koteishi, Yoichiro Kamimura, Yukihiro Miyanaga, Kohei Takeshita, Atsushi Nakagawa & Masahiro Ueda

Onsite GTP fuelling via DYNAMO1 drives division of mitochondria and peroxisomes
Biochemistry & Molecular BiologyНоя 06 2018Nature Communications

Yuuta Imoto, Yuichi Abe, Masanori Honsho, Kanji Okumoto, Mio Ohnuma, Haruko Kuroiwa, Tsuneyoshi Kuroiwa & Yukio Fujiki

Arabidopsis thaliana NGATHA1 transcription factor induces ABA biosynthesis by activating NCED3 gene during dehydration stress
Plant & Animal ScienceНоя 05 2018PNAS

Hikaru Sato, Hironori Takasaki, Fuminori Takahashi, Takamasa Suzuki, Satoshi Iuchi, Nobutaka Mitsuda, Masaru Ohme-Takagi, Miho Ikeda, Mitsunori Seo, Kazuko Yamaguchi-Shinozaki, and Kazuo Shinozaki

Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs
Cancer & ImmunologyНоя 05 2018The Journal of Immunology

Dana Bogdanova, Arata Takeuchi, Madoka Ozawa, Yasuhiro Kanda, M. Azizur Rahman, Burkhard Ludewig, Tatsuo Kinashi and Tomoya Katakai

Loss of TRIM29 alters keratin distribution to promote cell invasion in squamous cell carcinoma
Cancer & ImmunologyНоя 02 2018Cancer Research

Teruki Yanagi, masashi watanabe, Hiroo Hata, Shinya Kitamura, Keisuke Imafuku, Hiroko Yanagi, Akihiro Homma, Lei Wang, Hidehisa Takahashi, Hiroshi Shimizu and Shigetsugu Hatakeyama

Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure
Biomedical ResearchОкт 30 2018Nature Communications

Seitaro Nomura, Masahiro Satoh, Takanori Fujita, Tomoaki Higo, Tomokazu Sumida, Toshiyuki Ko, Toshihiro Yamaguchi, Takashige Tobita, Atsuhiko T. Naito, Masamichi Ito, Kanna Fujita, Mutsuo Harada, Haruhiro Toko, Yoshio Kobayashi, Kaoru Ito, Eiki Takimoto, Hiroshi Akazawa, Hiroyuki Morita, Hiroyuki Aburatani, Issei Komuro

Microglia mediate non‐cell‐autonomous cell death of retinal ganglion cells
NeuroscienceОкт 29 2018Glia

Akiko Takeda Youichi Shinozaki Kenji Kashiwagi Nobuhiko Ohno Kei Eto Hiroaki Wake Junichi Nabekura Schuichi Koizumi

Sexual rejection via a vomeronasal receptor-triggered limbic circuit
NeuroscienceОкт 26 2018Nature Communications

Takuya Osakada, Kentaro K. Ishii, Hiromi Mori, Ryo Eguchi, David M. Ferrero, Yoshihiro Yoshihara, Stephen D. Liberles, Kazunari Miyamichi and Kazushige Touhara

A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
Cell BiologyОкт 26 2018Nature Communications

Shin Murai, Yoshifumi Yamaguchi, Yoshitaka Shirasaki, Mai Yamagishi, Ryodai Shindo, Joanne M. Hildebrand, Ryosuke Miura, Osamu Nakabayashi, Mamoru Totsuka, Taichiro Tomida, Satomi Adachi-Akahane, Sotaro Uemura, John Silke, Hideo Yagita, Masayuki Miura & Hiroyasu Nakano

Mutual inhibition between PTEN and PIP3 generates bistability for polarity in motile cells
Cell BiologyОкт 26 2018Nature Communications

Satomi Matsuoka & Masahiro Ueda

Phospholipid flippases enable precursor B cells to flee engulfment by macrophages
Cancer & ImmunologyОкт 24 2018PNAS

Katsumori Segawa, Yuichi Yanagihashi, Kyoko Yamada, Chigure Suzuki, Yasuo Uchiyama, and Shigekazu Nagata

Uncoupled deposition of secondary wall polymers
Plant & Animal ScienceОкт 18 2018The Plant Cell

Yuto Takenaka, Yoichiro Watanabe, Mathias Schuetz, Faride Unda, Joseph Lee Hill, Pawittra Phookaew, Arata Yoneda, Shawn D. Mansfield, A. Lacey Samuels, Misato Ohtani, Taku Demura

Myoferlin-Mediated Lysosomal Exocytosis Regulates Cytotoxicity by Phagocytes
Cancer & ImmunologyОкт 17 2018The Journal of Immunology

Yuji Miyatake, Tomoyoshi Yamano and Rikinari Hanayama

ROSA26 reporter mouse lines and image analyses reveal the distinct region-specific cell behaviors in the visceral endoderm
Developmental BiologyОкт 16 2018Development

Takaya Abe, Natsumaro Kutsuna, Hiroshi Kiyonari, Yasuhide Furuta, Toshihiko Fujimori

Shootin1b Mediates a Mechanical Clutch to Produce Force for Neuronal Migration
NeuroscienceОкт 16 2018Cell Reports

Takunori Minegishi, Yasuyuki Uesugi, Naoko Kaneko, Wataru Yoshida, Kazunobu Sawamoto, Naoyuki Inagaki

Endocytic trafficking factor VPS45 is essential for spatial regulation of lens fiber differentiation in zebrafish
Developmental BiologyОкт 15 2018Development

Toshiaki Mochizuki, Yutaka Kojima, Yuko Nishiwaki, Tetsuya Harakuni, Ichiro Masai

Color opponency with a single kind of bistable opsin in the zebrafish pineal organ
NeuroscienceОкт 15 2018PNAS

Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Masahiko Hibi, Satoshi Tamotsu, Mitsumasa Koyanagi, and Akihisa Terakita

Impacts of Diabetes and an SGLT2 Inhibitor on the Glomerular Number and Volume in db/db Mice, as Estimated by Synchrotron Radiation Micro-CT at SPring-8
Biomedical ResearchОкт 12 2018EBioMedicine

Yumi Takiyama, Toshihiro Sera, Masanori Nakamura, Kanaki Ishizeki, Yasuaki Saijo, Tsuyoshi Yanagimachi, Manami Maeda, Ryoichi Bessho, Takao Takiyama, Hiroya Kitsunai, Hidemitsu Sakagami, Daisuke Fujishiro, Yukihiro Fujita, Yuichi Makino, Atsuko Abiko, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Tsuguhito Ota, Masakazu Haneda

A biological switching valve evolved in the female of a sex-role reversed cave insect to receive multiple seminal packages
Plant & Animal ScienceОкт 12 2018eLife

Kazunori Yoshizawa, Yoshitaka Kamimura, Charles Lienhard, Rodrigo L Ferreira, Alexander Blanke

NDP52 interacts with mitochondrial RNA poly (A) polymerase to promote mitophagy
Biochemistry & Molecular BiologyОкт 11 2018EMBO Reports

Norihiko Furuya, Soichiro Kakuta, Katsuhiko Sumiyoshi, Maya Ando, Risa Nonaka,Ayami Suzuki, Saiko Kazuno, Shinji Saiki, Nobutaka Hattori

Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex
NeuroscienceОкт 11 2018Cerebral Cortex

Keiko Nakanishi  Hiroyuki Niida  Hidenori Tabata  Tsuyoshi Ito  Yuki Hori Madoka Hattori  Yoshikazu Johmura  Chisato Yamada  Takashi Ueda  Kosei Takeuchi Kenichiro Yamada  Koh-ichi Nagata  Nobuaki Wakamatsu  Masashi Kishi  Y Albert Pan Shinya Ugawa  Shoichi Shimada  Joshua R Sanes  Yujiro Higashi  Makoto Nakanishi

The Pace of Neurogenesis Is Regulated by the Transient Retention of the Apical Endfeet of Differentiating Cells
NeuroscienceОкт 11 2018Cerebral Cortex

Jun Hatakeyama, Kenji Shimamura

Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response
Cancer & ImmunologyОкт 09 2018mBio

Hironori Bando, Youngae Lee, Naoya Sakaguchi, Ariel Pradipta, Ji Su Ma, Shun Tanaka, Yihong Cai, Jianfa Liu, Jilong Shen, Yoshifumi Nishikawa, Miwa Sasai, and Masahiro Yamamoto

Kinesin-binding–triggered conformation switching of microtubules contributes to polarized transport
Cell BiologyОкт 08 2018The Journal of Cell Biology

Tomohiro Shima, Manatsu Morikawa, Junichi Kaneshiro, Taketoshi Kambara, Shinji Kamimura, Toshiki Yagi, Hiroyuki Iwamoto, Sotaro Uemura, Hideki Shigematsu, Mikako Shirouzu, Taro Ichimura, Tomonobu M. Watanabe, Ryo Nitta, Yasushi Okada, Nobutaka Hirokawa

Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus
Developmental BiologyОкт 05 2018Development

Tomoko Watanabe, Takayoshi Yamamoto, Kohei Tsukano, Sayuki Hirano, Ayumi Horikawa, Tatsuo Michiue

RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability
Developmental BiologyОкт 04 2018Developmental Cell

Shou Soeda, Kaori Yamada-Nomoto, Tatsuo Michiue, Miho Ohsugi

Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis
Developmental BiologyОкт 03 2018Nature Communications

Chiharu Kimura-Yoshida, Kyoko Mochida, Masa-aki Nakaya, Takeomi Mizutani & Isao Matsuo

Application of the fluctuation theorem for non-invasive force measurement in living neuronal axons.
NeuroscienceОкт 03 2018Molecular Psychiatry

Hikari Tanaka, Kanoh Kondo, Xigui Chen, Hidenori Homma, Kazuhiko Tagawa, Aurelian Kerever, Shigeki Aoki, Takashi Saito, Takaomi Saido, Shin-ichi Muramatsu, Kyota Fujita & Hitoshi Okazawa

Direct Relay Pathways from Lemniscal Auditory Thalamus to Secondary Auditory Field in Mice
NeuroscienceОкт 01 2018Cerebral Cortex

Shinpei Ohga  Hiroaki Tsukano  Masao Horie  Hiroki Terashima  Nana Nishio Yamato Kubota  Kuniyuki Takahashi  Ryuichi Hishida  Hirohide Takebayashi Katsuei Shibuki

Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development
Cell BiologyСен 27 2018PLoS Genetics

Taichi Hara, Ikuko Maejima, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, Satoshi Tsukamoto, Mika Tsunoda, Aguri Ono, Shota Yamakoshi, Satoshi Oikawa, Ken Sato

De novo PHACTR1 mutations in West syndrome and their pathophysiological effects
NeuroscienceСен 26 2018Brain

Nanako Hamada  Shunsuke Ogaya  Mitsuko Nakashima  Takuma Nishijo  Yuji Sugawara Ikuko Iwamoto  Hidenori Ito  Yuki Maki  Kentaro Shirai  Shimpei Baba  Koichi Maruyama Hirotomo Saitsu  Mitsuhiro Kato  Naomichi Matsumoto  Toshihiko Momiyama Koh-ichi Nagata

Crystal structure of the red light-activated channelrhodopsin Chrimson
Biochemistry & Molecular BiologyСен 26 2018Nature Communications

Kazumasa Oda, Johannes Vierock, Satomi Oishi, Silvia Rodriguez-Rozada, Reiya Taniguchi, Keitaro Yamashita, J. Simon Wiegert, Tomohiro Nishizawa, Peter Hegemann & Osamu Nureki

mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility
Cell BiologyСен 26 2018PLoS Biology

Satoko Sakamoto, Dean Thumkeo, Hiroshi Ohta, Zhen Zhang, Shuangru Huang, Pakorn Kanchanawong, Takayoshi Fuu, Sadanori Watanabe, Kentaro Shimada, Yoshitaka Fujihara, Shosei Yoshida, Masahito Ikawa, Naoki Watanabe, Mitinori Saitou, Shuh Narumiya

The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formation
Cell BiologyСен 25 2018PNAS

Tetsuya Kotani, Hiromi Kirisako, Michiko Koizumi, Yoshinori Ohsumi, and Hitoshi Nakatogawa

A Single Pheromone Receptor Gene Conserved across 400 My of Vertebrate Evolution
Biochemistry & Molecular BiologyСен 24 2018Molecular Biology and Evolution

Hikoyu Suzuki  Hidefumi Nishida  Hiro Kondo  Ryota Yoda  Tetsuo Iwata Kanako Nakayama  Takayuki Enomoto  Jiaqi Wu  Keiko Moriya-Ito Masao Miyazaki  Yoshihiro Wakabayashi  Takushi Kishida  Masataka Okabe Yutaka Suzuki  Takehiko Ito  Junji Hirota  Masato Nikaido

Opposite roles in short-term plasticity for N-type and P/Q-type voltage-dependent calcium channels in GABAergic neuronal connections in the rat cerebral cortex
NeuroscienceСен 24 2018The Journal of Neuroscience

Kiyofumi Yamamoto and Masayuki Kobayashi

Retinal detachment-induced Müller glial cell swelling activates TRPV4 ion channels and triggers photoreceptor death at body temperature
NeuroscienceСен 24 2018The Journal of Neuroscience

Hidetaka Matsumoto, Shouta Sugio, François Seghers, David Krizaj, Hideo Akiyama, Yasuki Ishizaki, Philippe Gailly and Koji Shibasaki

The photosystem II repair cycle requires FtsH turnover through the EngA GTPase
Plant & Animal ScienceСен 21 2018Plant Physiology

Yusuke Kato, Kiwamu Hyodo, Wataru Sakamoto

Generation of human oogonia from induced pluripotent stem cells in vitro
Stem CellsСен 20 2018Science

Chika Yamashiro, Kotaro Sasaki, Yukihiro Yabuta, Yoji Kojima, Tomonori Nakamura, Ikuhiro Okamoto, Shihori Yokobayashi, Yusuke Murase, Yukiko Ishikura, Kenjiro Shirane, Hiroyuki Sasaki, Takuya Yamamoto, Mitinori Saitou

Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
Cancer & ImmunologyСен 20 2018Cell

Takaaki Yasuhara, Reona Kato, Yoshihiko Hagiwara, Bunsyo Shiotani, Motohiro Yamauchi, Shinichiro Nakada, Atsushi Shibata, Kiyoshi Miyagawa

Regulatory cocktail for dopaminergic neurons in a protovertebrate identified by whole-embryo single-cell transcriptomics
Developmental BiologyСен 18 2018Gene & Development

Takeo Horie, Ryoko Horie, Kai Chen, Chen Cao, Masashi Nakagawa, Takehiro G. Kusakabe, Noriyuki Satoh, Yasunori Sasakura, and Michael Levine

SIRT2‐mediated inactivation of p73 is required for glioblastoma tumorigenicity
Cancer & ImmunologyСен 13 2018EMBO Reports

Kosuke Funato, Tomoatsu Hayashi, Kanae Echizen, Lumi Negishi, Naomi Shimizu, Ryo Koyama‐Nasu, Yukiko Nasu‐Nishimura, Yasuyuki Morishita, Viviane Tabar, Tomoki Todo, Yasushi Ino, Akitake Mukasa, Nobuhito Saito, Tetsu Akiyama

Repeated injection of KMRC011, a medical countermeasure for radiation, can cause adverse health effects in cynomolgus monkeys
PharmacologyСен 11 2018Journal of Applied Toxicology

Hong‐Soo Lee, Yoo‐Jin Park, Doo‐Wan Cho, Su‐Cheol Han, Soo Youn Jun, Gi Mo Jung, Woo‐Jong Lee, Chi‐Min Choi, Eun‐Jung Park, Son‐Il Pak


  

Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity
Biomedical ResearchСен 11 2018Cell Reports

Ryutaro Ikegami, Ippei Shimizu, Takeshi Sato, Yohko Yoshida, Yuka Hayashi, Masayoshi Suda, Goro Katsuumi, Ji Li, Takayuki Wakasugi, Yasuhiko Minokoshi, Shiki Okamoto, Eiichi Hinoi, Søren Nielsen, Naja Zenius Jespersen, Camilla Scheele, Tomoyoshi Soga, Tohru Minamino

AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
Cell BiologyСен 10 2018Nature Communications

Keisuke Ikawa & Kaoru Sugimura

TRPM2 exacerbates central nervous system inflammation in experimental autoimmune encephalomyelitis by increasing production of CXCL2 chemokines
NeuroscienceСен 10 2018The Journal of Neuroscience

Masato Tsutsui, Ryo Hirase, Sakie Miyamura, Kazuki Nagayasu, Takayuki Nakagawa, Yasuo Mori, Hisashi Shirakawa and Shuji Kaneko

Rational Design for Multicolor Flavone-Based Fluorophores with Aggregation-Induced Emission Enhancement Characteristics and Applications in Mitochondria-Imaging
Biochemistry & Molecular BiologyСен 07 2018Molecules

Liyan Liu, Yaohui Lei, Jianhui Zhang, Na Li, Fan Zhang, Huaqiao Wang and Feng He

CAMSAP3 maintains neuronal polarity through regulation of microtubule stability
Developmental BiologyСен 06 2018PNAS

Varisa Pongrakhananon, Hiroko Saito, Sylvain Hiver, Takaya Abe, Go Shioi, Wenxiang Meng, and Masatoshi Takeichi

Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance
Cell BiologyСен 06 2018The Journal of Cell Biology

Akari Hagiwara, Yosuke Kitahara, Chad Paul Grabner, Christian Vogl, Manabu Abe, Ryo Kitta, Keisuke Ohta, Keiichiro Nakamura, Kenji Sakimura, Tobias Moser, Akinori Nishi, and Toshihisa Ohtsuka

Actin reorganization promotes root cell elongation
Plant & Animal ScienceСен 05 2018Plant Physiology

Hirotomo Takatsuka, Takumi Higaki, Masaaki Umeda

Coupling of bone resorption and formation by RANKL reverse signalling
Biomedical ResearchСен 05 2018Nature

Yuki Ikebuchi, Shigeki Aoki, Masashi Honma, Madoka Hayashi, Yasutaka Sugamori, Masud Khan, Yoshiaki Kariya, Genki Kato, Yasuhiko Tabata, Josef M. Penninger, Nobuyuki Udagawa, Kazuhiro Aoki & Hiroshi Suzuki

Cell-to-Cell Heterogeneity in p38-Mediated Cross-Inhibition of JNK Causes Stochastic Cell Death
Cell BiologyСен 04 2018Cell Reports

Haruko Miura, Yohei Kondo, Michiyuki Matsuda, Kazuhiro Aoki

Super-wide-field two-photon imaging with a micro-optical device moving in post-objective space
NeuroscienceСен 04 2018Nature Communications

Shin-Ichiro Terada, Kenta Kobayashi, Masamichi Ohkura, Junichi Nakai & Masanori Matsuzaki

Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior
NeuroscienceАвг 30 2018Neuron

Xinzhu Yu, Anna M.W. Taylor, Jun Nagai, Peyman Golshani, Christopher J. Evans, Giovanni Coppola, Baljit S. Khakh

Quantitative Lipid Imaging Reveals a New Signaling Function of Phosphatidylinositol-3,4-Bisphophate: Isoform- and Site-Specific Activation of Akt
Cell BiologyАвг 30 2018Molecular Cell

Shu-Lin Liu, Zhi-Gang Wang, Yusi Hu, Yao Xin, Indira Singaram, Sukhamoy Gorai, Xin Zhou, Yoonjung Shim, Jung-Hyun Min, Liang-Wei Gong, Nissim Hay, Jin Zhang, Wonhwa Cho

Thalamocortical Axonal Activity in Motor Cortex Exhibits Layer-Specific Dynamics during Motor Learning
NeuroscienceАвг 30 2018Neuron

Yasuyo H. Tanaka, Yasuhiro R. Tanaka, Masashi Kondo, Shin-Ichiro Terada, Yasuo Kawaguchi, Masanori Matsuzaki

14-3-3εa directs the pulsatile transport of basal factors toward the apical domain for lumen growth in tubulogenesis
Developmental BiologyАвг 29 2018PNAS

Yuji Mizotani, Mayu Suzuki, Kohji Hotta, Hidenori Watanabe, Kogiku Shiba, Kazuo Inaba, Etsu Tashiro, Kotaro Oka, and Masaya Imoto

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice
Cell BiologyАвг 28 2018The EMBO Journal

Steven Findlay, John Heath, Vincent M Luo, Abba Malina, Théo Morin, Yan Coulombe, Billel Djerir, Zhigang Li, Arash Samiei, Estelle Simo‐Cheyou, Martin Karam, Halil Bagci, Dolev Rahat, Damien Grapton, Elise G Lavoie, Christian Dove, Husam Khaled, Hellen Kuasne, Koren K Mann, Kathleen Oros Klein, Celia M Greenwood, Yuval Tabach, Morag Park, Jean‐Francois Côté, Jean‐Yves Masson, Alexandre Maréchal, Alexandre Orthwein

Muscarinic acetylcholine receptors Chrm1 and Chrm3 are essential for REM sleep
Biomedical ResearchАвг 28 2018Cell Reports

Yasutaka Niwa, Genki N. Kanda, Rikuhiro G. Yamada, Shoi Shi, Genshiro A. Sunagawa, Maki Ukai-Tadenuma, Hiroshi Fujishima, Naomi Matsumoto, Koh-hei Masumoto, Mamoru Nagano, Takeya Kasukawa, James Galloway, Dimitri Perrin, Yasufumi Shigeyoshi, Hideki Ukai, Hiroshi Kiyonari, Kenta Sumiyama, Hiroki R. Ueda

Prd1 associates with the clathrin adaptor α-Adaptin and the kinesin-3 Imac/Unc-104 to govern dendrite pruning in Drosophila
NeuroscienceCell BiologyАвг 24 2018PLoS Biology

Wenhui Zong, Yan Wang, Quan Tang, Heng Zhang, Fengwei Yu

Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
MicrobiologyАвг 24 2018Nature Communications

Keisuke Nakashima, Satoshi Kimura, Yu Ogawa, Soichi Watanabe, Satoshi Soma, Toyoji Kaneko, Lixy Yamada, Hitoshi Sawada, Che-Huang Tung, Tsai-Ming Lu, Jr-Kai Yu, Alejandro Villar-Briones, Sakura Kikuchi & Noriyuki Satoh 

Retinal detachment-induced Müller glial cell swelling activates TRPV4 ion channels and triggers photoreceptor death at body temperature
NeuroscienceАвг 24 2018The Journal of Neuroscience

Hidetaka Matsumoto, Shouta Sugio, François Seghers, David Krizaj, Hideo Akiyama, Yasuki Ishizaki, Philippe Gailly and Koji Shibasaki

Investigation of a-Synuclein Amyloid Fibrils Using the Fluorescent Probe Thioflavin T
Biochemistry & Molecular BiologyАвг 23 2018International Journal of Molecular Sciences

Anna I. Sulatskaya, Natalia P. Rodina, Maksim I. Sulatsky, Olga I. Povarova, Iuliia A. Antifeeva, Irina M. Kuznetsova and Konstantin K. Turoverov

Efficient Perovskite Solar Cells Fabricated Through CsCl‐Enhanced PbI2 Precursor via Sequential Deposition
Materials ScienceАвг 23 2018Advanced Materials

Qi Li, Yicheng Zhao, Rui Fu, Wenke Zhou, Yao Zhao, Xin Liu, Dapeng Yu, Qing Zhao

Monitoring and Updating of Action Selection for Goal-Directed Behavior through the Striatal Direct and Indirect Pathways
NeuroscienceАвг 23 2018Neuron

Satoshi Nonomura, Kayo Nishizawa, Yutaka Sakai, Yasuo Kawaguchi, Shigeki Kato, Motokazu Uchigashima, Masahiko Watanabe, Ko Yamanaka, Kazuki Enomoto, Satomi Chiken, Hiromi Sano, Shogo Soma, Junichi Yoshida, Kazuyuki Samejima, Masaaki Ogawa, Kazuto Kobayashi, Atsushi Nambu, Yoshikazu Isomura, Minoru Kimura

Transcriptional switch for programmed cell death in pith parenchyma of sorghum stems
Plant & Animal ScienceАвг 23 2018PNAS

Masaru Fujimoto, Takashi Sazuka, Yoshihisa Oda, Hiroyuki Kawahigashi, Jianzhong Wu, Hideki Takanashi, Takayuki Ohnishi, Jun-ichi Yoneda, Motoyuki Ishimori, Hiromi Kajiya-Kanegae, Ken-ichiro Hibara, Fumiko Ishizuna, Kazuo Ebine, Takashi Ueda, Tsuyoshi Tokunaga, Hiroyoshi Iwata, Takashi Matsumoto, Shigemitsu Kasuga, Jun-ichi Yonemaru, Nobuhiro Tsutsumi

Inhibition of MicroRNA-96 Ameliorates Cognitive Impairment and Inactivation Autophagy Following Chronic Cerebral Hypoperfusion in the Rat
Cell BiologyАвг 22 2018Cellular Physiology and BioBiochemistry & Molecular Biology

Liu P., Liu P., Wang Z., Fang S., Liu Y., Wang J., Liu W., Wang N., Chen L., Wang J., Zhang H., Wang L

OsPKS1 is required for sexine layer formation, which shows functional conservation between rice and Arabidopsis
Plant & Animal ScienceАвг 22 2018Plant Science

Qiang-Sheng Shi, Kai-Qi Wang, Yue-Ling Li, Lei Zhou, Shuang-Xi Xiong, Yu Han, Yan-Fei Zhang, Nai-Ying Yang, Zhong-Nan Yang, Jun Zhu

The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1
Biochemistry & Molecular BiologyАвг 22 2018The Journal of Biological Chemistry

Maria Horiuchi, Takahisa Kuga, Youhei Saito, Maiko Nagano, Jun Adachi, Takeshi Tomonaga, Naoto Yamaguchi, and Yuji Nakayama

Chemical Landscape for Tissue Clearing based on Hydrophilic Reagents
BioimagingАвг 21 2018Cell Reports

Kazuki Tainaka, Tatsuya C. Murakami, Etsuo A. Susaki, Chika Shimizu, Rie Saito, Kei Takahashi, Akiko Hayashi-Takagi, Hiroshi Sekiya, Yasunobu Arima, Satoshi Nojima, Masako Ikemura, Tetsuo Ushiku, Yoshihiro Shimizu, Masaaki Murakami, Kenji F. Tanaka, Masamitsu Iino, Haruo Kasai, Toshikuni Sasaoka, Kazuto Kobayashi, Kohei Miyazono, Eiichi Morii, Tadashi Isa, Masashi Fukayama, Akiyoshi Kakita and Hiroki R. Ueda

The photosystem II repair cycle requires FtsH turnover through the EngA GTPase
Plant & Animal ScienceАвг 21 2018Plant Physiology

Yusuke Kato, Kiwamu Hyodo, Wataru Sakamoto

Deficient humoral responses and disrupted B-cell immunity are associated with fatal SFTSV infection
Cancer & ImmunologyАвг 20 2018Nature Communications

Peixin Song, Nan Zheng, Yong Liu, Chen Tian, Xilin Wu, Xiaohua Ma, Deyan Chen, Xue Zou, Guiyang Wang, Huanru Wang, Yongyang Zhang, Sufang Lu, Chao Wu & Zhiwei Wu

Synaptotagmin-associated endoplasmic reticulum-plasma membrane contact sites are localized to immobile ER tubules
Plant & Animal ScienceАвг 20 2018Plant Physiology

Kazuya Ishikawa, Kentaro Tamura, Haruko Ueda, Yoko Ito, Akihiko Nakano, Ikuko Hara-Nishimura, Tomoo Shimada

ANGUSTIFOLIA contributes to the regulation of three-dimensional morphogenesis in the liverwort Marchantia polymorpha
Developmental BiologyАвг 20 2018Development

Tomoyuki Furuya, Koro Hattori, Yoshitaka Kimori, Sakiko Ishida, Ryuichi Nishihama, Takayuki Kohchi, Hirokazu Tsukaya

Substrate elasticity regulates adipose-derived stromal cell differentiation towards osteogenesis and adipogenesis through β-catenin transduction
Biomedical ResearchАвг 19 2018Acta Biomaterialia

Jing Xie, Demao Zhang, Chenchen Zhou, Quan Yuan, Ling Ye, Xuedong Zhou

Pluronic F127 blended polycaprolactone scaffolds via e-jetting for esophageal tissue engineering
Biomedical ResearchАвг 17 2018Journal of Materials Science: Materials in Medicine

Bin Wu, Nobuyoshi Takeshita, Yang Wu, Sanjairaj Vijayavenkataraman, Khek Yu Ho, Wen Feng Lu, Jerry Ying Hsi Fuh

Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice
NeuroscienceАвг 16 2018PLoS Genetics

Toru Yoshihara, Hiroyuki Satake, Toshikazu Nishie, Nozomu Okino, Toshihisa Hatta, Hiroki Otani, Chie Naruse, Hiroshi Suzuki, Kazushi Sugihara, Eikichi Kamimura, Noriyo Tokuda, Keiko Furukawa, Koichi Fururkawa, Makoto Ito, Masahide Asano

6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway
Cell BiologyАвг 16 2018Autophagy

Yasuomi Urano, Chinatsu Mori, Ayano Fuji, Keito Konno, Takayuki Yamamoto, Shohei Yashirogi, Mayu Ando, Yoshiro Saito & Noriko Noguchi

Biased genome editing using the local accumulation of DSB repair molecules system
Biochemistry & Molecular BiologyАвг 16 2018Nature Communications

Shota Nakade, Keiji Mochida, Atsushi Kunii, Kazuki Nakamae, Tomomi Aida, Kohichi Tanaka, Naoaki Sakamoto, Tetsushi Sakuma & Takashi Yamamoto

Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning
NeuroscienceАвг 16 2018Neuron

Wataru Kakegawa, Akira Katoh, Sakae Narumi, Eriko Miura, Junko Motohashi, Akiyo Takahashi, Kazuhisa Kohda, Yugo Fukazawa, Michisuke Yuzaki, Shinji Matsuda

Identification of 16,25-Odiacetyl-cucurbitane F and 25-O-acetyl-23,24-dihydrocucurbitacin F as novel anti-cancer chemicals
Cancer & ImmunologyBiochemistry & Molecular BiologyАвг 15 2018Royal Society Open Science

Wenxue Wang, Haoran Yang, Ying Li, Zhongfei Zheng, Yongjun Liu, Haiyang Wang, Yanling Mu, Qingqiang Yao

Multiple-Condition Analysis in a Retrievable Subcutaneous Animal Model for Drug Screening on Full Pancreatic Tissue Digest
Biomedical ResearchАвг 14 2018ASSAY and Drug Development Technologies

Tim W.G.M. Spitters, Parker L. Andersen, Chloé Martel, and Patrick Vermette

The C. elegans BRCA2-ALP/Enigma Complex Regulates Axon Regeneration via a Rho GTPase-ROCK-MLC Phosphorylation Pathway
Cancer & ImmunologyАвг 14 2018Cell Reports

Tatsuhiro Shimizu, Strahil Iv. Pastuhov, Hiroshi Hanafusa, Kunihiro Matsumoto, Naoki Hisamoto

Tumor Oxygenation and Hypoxia Inducible Factor-1 Functional Inhibition via a Reactive Oxygen Species Responsive Nanoplatform for Enhancing Radiation Therapy and Abscopal Effects
Biochemistry & Molecular BiologyАвг 13 2018ACS Nano

Lingtong Meng, Yali Cheng, Xiaoning Tong, Shaoju Gan, Yawen Ding, Yu Zhang, Chao Wang, Lei Xu, Yishen Zhu, Jinhui Wu , Yiqiao Hu, and Ahu Yuan

Endoribonuclease ENDU-2 regulates multiple traits including cold tolerance via cell autonomous and nonautonomous controls in Caenorhabditis elegans
NeuroscienceАвг 13 2018PNAS

Tomoyo Ujisawa, Akane Ohta, Tatsuya Ii, Yohei Minakuchi, Atsushi Toyoda, Miki Ii, and Atsushi Kuhara

Light-induced mechanical response in crosslinked liquid-crystalline polymers with photoswitchable glass transition temperatures
Materials ScienceАвг 13 2018Nature Communications

Youfeng Yue, Yasuo Norikane, Reiko Azumi & Emiko Koyama 

Resveratrol-induced p53 activation is associated with autophagy in mouse embryonic stem cells
Stem CellsАвг 08 2018Biochemical and Biophysical Research Communications

Irina I. Suvorova, Aleksandra R. Knyazeva, Valery A. Pospelov

Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance
NeuroscienceАвг 07 2018eLife

Kentarou Baba, Wataru Yoshida, Michinori Toriyama, Tadayuki Shimada, Colleen F Manning, Michiko Saito, Kenji Kohno, James S Trimmer, Rikiya Watanabe, Naoyuki Inagaki

Protocadherin-mediated cell repulsion controls the central topography and efferent projections of the abducens nucleus
Developmental BiologyАвг 07 2018Cell Reports

Kazuhide Asakawa, Koichi Kawakami

Variation in bradyrhizobial NopP effector determines symbiotic incompatibility with Rj2-soybeans via effector-triggered immunity
Plant & Animal ScienceАвг 07 2018Nature Communications

Masayuki Sugawara, Satoko Takahashi, Yosuke Umehara, Hiroya Iwano, Hirohito
Tsurumaru, Haruka Odake, Yuta Suzuki, Hitoshi Kondo, Yuki Konno, Takeo Yamakawa,
Shusei Sato, Hisayuki Mitsui, Kiwamu Minamisawa

Pectin RG-I rhamnosyltransferases represent a novel plant-specific glycosyltransferase family
Plant & Animal ScienceАвг 06 2018Nature Plants

Yuto Takenaka, Kohei Kato, Mari Ogawa-Ohnishi, Kana Tsuruhama, Hiroyuki Kajiura, Kenta Yagyu, Atsushi Takeda, Yoichi Takeda, Tadashi Kunieda, Ikuko Hara-Nishimura, Takeshi Kuroha, Kazuhiko Nishitani, Yoshikatsu Matsubayashi & Takeshi Ishimizu 

Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
Cancer & ImmunologyАвг 06 2018Nature Communications

Naoki Hisamoto, Anna Tsuge, Strahil Iv. Pastuhov, Tatsuhiro Shimizu, Hiroshi Hanafusa & Kunihiro Matsumoto

Bipolar dispersal of red-snow algae
Plant & Animal ScienceАвг 06 2018Nature Communications

Takahiro Segawa, Ryo Matsuzaki, Nozomu Takeuchi, Ayumi Akiyoshi, Francisco Navarro, Shin Sugiyama, Takahiro Yonezawa & Hiroshi Mori 

Effects of biphasic and monophasic electrical stimulation on mitochondrial dynamics, cell apoptosis, and cell proliferation
Cell BiologyАвг 04 2018Journal of Cellular Physiology

Maria R. Love, Jirapas Sripetchwandee, Siripong Palee, Siriporn C. Chattipakorn, Morton M. Mower, Nipon Chattipakorn

Loss of Fam60a, a Sin3a subunit, results in embryonic lethality and is associated with aberrant methylation at a subset of gene promoters
Developmental BiologyАвг 02 2018eLife

Ryo Nabeshima, Osamu Nishimura, Takako Maeda, Natsumi Shimizu, Takahiro Ide, Kenta Yashiro, Yasuo Sakai, Chikara Meno, Mitsutaka Kadota, Hidetaka Shiratori, Shigehiro Kuraku, Hiroshi Hamada

A Rho-based reaction-diffusion system governs cell wall patterning in metaxylem vessels
Plant & Animal ScienceАвг 01 2018Scientific Reports

Yoshinobu Nagashima, Satoru Tsugawa, Atsushi Mochizuki, Takema Sasaki, Hiroo Fukuda & Yoshihisa Oda

CD30 characterizes polylobated lymphocytes and disease progression in HTLV-1-infected individuals
Cancer & ImmunologyАвг 01 2018Clinical Cancer Research

Makoto Nakashima, Tadanori Yamochi, Mariko Watanabe, Kaoru Uchimaru, Atae Utsunomiya, Masaaki Higashihara, Toshiki Watanabe and Ryouichi Horie

Antineoplastic Actions of Cinnamic Acids and Their Dimers in Breast Cancer Cells: A Comparative Study
Cancer & ImmunologyИюл 30 2018Anticancer Research

MEGAN HUNKE, WUILIAN MARTINEZ, AKSHAY KASHYAP, TREYVON BOKOSKIE, MAHESH PATTABIRAMAN and SURABHI CHANDRA

Designed peptides that assemble into cross-α amyloid-like structures
Biochemistry & Molecular BiologyИюл 30 2018Nature Chemical Biology

Shao-Qing Zhang, Hai Huang, Junjiao Yang, Huong T. Kratochvil, Marco Lolicato, Yanxin Liu, Xiaokun Shu, Lijun Liu & William F. DeGrado

Three-dimensional induction of dorsal, intermediate and ventral spinal cord tissues from human pluripotent stem cells
Developmental BiologyИюл 30 2018Development

Takenori Ogura, Hideya Sakaguchi, Susumu Miyamoto, Jun Takahashi

Differential expression of Lutheran/BCAM regulates biliary tissue remodeling in ductular reaction during liver regeneration
Biomedical ResearchИюл 30 2018eLife

Yasushi Miura, Satoshi Matsui, Naoko Miyata, Kenichi Harada, Yamato Kikkawa, Masaki Ohmuraya, Kimi Araki, Shinya Tsurusaki, Hitoshi Okochi, Nobuhito Goda, Atsushi Miyajima, Minoru TanaKa

Enhanced water splitting under modal strong coupling conditions
Materials ScienceИюл 30 2018Nature Nanotechnology

Xu Shi, Kosei Ueno, Tomoya Oshikiri, Quan Sun, Keiji Sasaki & Hiroaki Misawa

Anti-tumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination
Cancer & ImmunologyИюл 25 2018Blood

Yasushi Akahori, Linan Wang, Motohiro Yoneyama, Naohiro Seo, Satoshi Okumura, Yoshihiro Miyahara, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, Hiroaki Ikeda, Takehiro Maki, Hiroshi Fujiwara, Yoshiki Akatsuka, Takuma Kato and Hiroshi Shiku

Solid-Phase Total Synthesis and Dual Mechanism of Action of the Channel-Forming 48-mer Peptide Polytheonamide B
NeuroscienceИюл 24 2018The Journal of the American Chemical Society

Atsushi Hayata, Hiroaki Itoh, Masayuki Inoue

Construction of integrated gene logic-chip
Biochemistry & Molecular BiologyИюл 23 2018Nature Nanotechnology

Takeya Masubuchi, Masayuki Endo, Ryo Iizuka, Ayaka Iguchi, Dong Hyun Yoon, Tetsushi Sekiguchi, Hao Qi, Ryosuke Iinuma, Yuya Miyazono, Shuichi Shoji, Takashi Funatsu, Hiroshi Sugiyama, Yoshie Harada, Takuya Ueda & Hisashi Tadakuma

MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining
Cell BiologyИюл 19 2018Molecular Cell

Putzer J. Hung, Britney Johnson, Bo-Ruei Chen, Andrea K. Byrum, Andrea L. Bredemeyer, William T. Yewdell, Tanya E. Johnson, Brian J. Lee, Shruthi Deivasigamani, Issa Hindi, Parmeshwar Amatya, Michael L. Gross, Tanya T. Paull, David J. Pisapia, Jayanta Chaudhuri, John J.H. Petrini, Nima Mosammaparast, Gaya K. Amarasinghe, Shan Zha, Jessica K. Tyler, Barry P. Sleckman

Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus
Developmental BiologyИюл 19 2018Nature Communications

Keishi Kishimoto, Masaru Tamura, Michiru Nishita, Yasuhiro Minami, Akira Yamaoka, Takaya Abe, Mayo Shigeta & Mitsuru Morimoto

Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum
NeuroscienceИюл 19 2018Nature Communications

Hisako Nakayama, Manabu Abe, Chie Morimoto, Tadatsune Iida, Shigeo Okabe, Kenji Sakimura & Kouichi Hashimoto

SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix
Biomedical ResearchИюл 19 2018Nature Communications

Masatoshi Fukuda, Tatsuya Yoshizawa, Md. Fazlul Karim, Shihab U. Sobuz, Wataru Korogi, Daiki Kobayasi, Hiroki Okanishi, Masayoshi Tasaki, Katsuhiko Ono, Tomohiro Sawa, Yoshifumi Sato, Mami Chirifu, Takeshi Masuda, Teruya Nakamura, Hironori Tanoue, Kazuhisa Nakashima, Yoshihiro Kobashigawa, Hiroshi Morioka, Eva Bober, Sumio Ohtsuki, Yuriko Yamagata, Yukio Ando, Yuichi Oike, Norie Araki, Shu Takeda, Hiroshi Mizuta & Kazuya Yamagata

Expression profile of the STAND protein Nwd1 in the developing and mature mouse central nervous system
NeuroscienceИюл 13 2018Journal of Comparative Neurology

Seiya Yamada  Shin‐ichi Sakakibara

Turbulence activates platelet biogenesis to enable clinical scale ex vivo production
Stem CellsИюл 12 2018Cell

Yukitaka Ito, Sou Nakamura, Naoshi Sugimoto, Tomohiro Shigemori, Yoshikazu Kato, Mikiko Ohno, Shinya Sakuma, Keitaro Ito, Hiroki Kumon, Hidenori Hirose, Haruki Okamoto, Masayuki Nogawa, Mio Iwasaki, Shunsuke Kihara, Kosuke Fujio, Takuya Matsumoto, Natsumi Higashi, Kazuya Hashimoto, Akira Sawaguchi, Ken-ichi Harimoto, Masato Nakagawa, Takuya Yamamoto, Makoto Handa, Naohide Watanabe, Eiichiro Nishi, Fumihito Arai, Satoshi Nishimura, Koji Eto

BMP signaling downstream of the Highwire E3 ligase sensitizes nociceptors
NeuroscienceИюл 12 2018PLoS Genetics

Ken Honjo and W. Daniel Tracey

Downregulation of splicing regulator RBFOX1 compromises visual depth perception
NeuroscienceИюл 12 2018PLOS One

Lei Gu, Dean Bok, Fei Yu, Joseph Caprioli, Natik Piri 

Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells
Stem CellsИюл 10 2018Stem Cell Reports

Leqian Yu, Junjun Li, Jiayin Hong, Yasuhiro Takashima, Nanae Fujimoto, Minako Nakajima, Akihisa Yamamoto, Xiaofeng Dong, Yujiao Dang, Yu Hou, Wei Yang, Itsunari Minami, Keisuke Okita, Motomu Tanaka, Chunxiong Luo, Fuchou Tang, Yong Chen, Chao Tang, Hidetoshi Kotera, Li Liu

Different Roles of Myocardial ROCK1 and ROCK2 in Cardiac Dysfunction and Postcapillary Pulmonary Hypertension in Mice
Biomedical ResearchИюл 09 2018PNAS

Shinichiro Sunamura, Kimio Satoh, Ryo Kurosawa, Tomohiro Ohtsuki, Nobuhiro Kikuchi, Md. Elias-Al-Mamun, Toru Shimizu, Shohei Ikeda, Kota Suzuki, Taijyu Satoh, Junichi Omura, Masamichi Nogi, Kazuhiko Numano, Mohammad Abdul Hai Siddique, Satoshi Miyata, Masahito Miura, and Hiroaki Shimokawa

A Highly Photostable Near-infrared Labeling Agent Based on a Phospha-rhodamine Enables Long-term and Deep Imaging
Biochemistry & Molecular BiologyИюл 08 2018Angewandte Chemie International Edition

Marek Grzybowski, Masayasu Taki, Kieko Senda, Yoshikatsu Sato, Tetsuro Ariyoshi, Yasushi Okada, Ryosuke Kawakami, Takeshi Imamura, and Shigehiro Yamaguchi

Cellular localization of the K+‐dependent Na+‐Ca2+ exchanger NCKX5 and the role of the cytoplasmic loop in its distribution in pigmented cells
Cell BiologyИюл 07 2018Pigment Cell & Melanoma

Tatiana P. Rogasevskaia, Robert T. Szerencsei, Ali H. Jalloul, Frank Visser, Robert J. Winkfein, Paul P.M. Schnetkamp

Status of KRAS in iPSCs Impacts upon Self-Renewal and Differentiation Propensity
Stem CellsИюл 05 2018Stem Cell Reports

Kenji Kubara, Kazuto Yamazaki, Yasuharu Ishihara, Takuya Naruto, Huan-Ting Lin, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Masashi Ito, Kappei Tsukahara, Tomohiro Morio, Masatoshi Takagi, Makoto Otsu

High-throughput imaging flow cytometry by optofluidic time-stretch microscopy
BioimagingИюл 05 2018Nature Protocols

Cheng Lei, Hirofumi Kobayashi, Yi Wu, Ming Li, Akihiro Isozaki, Atsushi Yasumoto, Hideharu Mikami, Takuro Ito, Nao Nitta, Takeaki Sugimura, Makoto Yamada, Yutaka Yatomi, Dino Di Carlo, Yasuyuki Ozeki & Keisuke Goda

A Switch-like Activation Relay of EGFR-ERK Signaling Regulates a Wave of Cellular Contractility For Epithelial Invagination
Developmental BiologyИюл 05 2018Developmental Cell

Yosuke Ogura, Fu-Lai Wen, Mustafa M. Sami, Tatsuo Shibata, Shigeo Hayashi

25‐Hydroxycholesterol protects against acute lung injury via targeting MD‐2
Cancer & ImmunologyИюл 05 2018J Cell Mol Med

Wei Ouyang, Hui Zhou, Chao Liu, Shiwei Wang, Yu Han, Jingyan Xia, Feng Xu

Lateral Size Scaling Effect during Discontinuous Dewetting
Materials ScienceИюл 04 2018Advanced Materials Interfaces

Yinyin Lin, Zhongsheng Wu, Mengying Zhang, Jinbo Wu, Weijia Wen

Characterization of Peribiliary Gland–Constituting Cells Based on Differential Expression of Trophoblast Cell Surface Protein 2 (Trop2) in Biliary Tract
Cell BiologyИюл 03 2018American Journal of Pathology

Satoshi Matsui, Kenichi Harada, Naoko Miyata, Hitoshi Okochi, Atsushi Miyajima, Minoru Tanaka

MTSS1 regulation of actin-nucleating formin DAAM1 in dendritic filopodia determines final dendritic configuration of Purkinje cells
NeuroscienceИюл 03 2018Cell Reports

Kelly Kawabata Galbraith, Kazuto Fujishima, Hiroaki Mizuno, Sung-Jin Lee, Takeshi Uemura, Kenji Sakimura, Masayoshi Mishina, Naoki Watanabe, Mineko Kengaku

Forebrain Ptf1a is required for sexual differentiation of the brain.
Biomedical ResearchИюл 03 2018Cell Reports

Tomoyuki Fujiyama, Satoshi Miyashita, Yousuke Tsuneoka, Kazumasa Kanemaru, Miyo Kakizaki, Satomi Kanno, Yukiko Ishikawa, Mariko Yamashita, Tomoo Owa, Mai Nagaoka, Yoshiya Kawaguchi, Yuchio Yanagawa, Mark A. Magnuson, Masafumi Muratani, Akira Shibuya, Yo-ichi Nabeshima, Masashi Yanagisawa, Hiromasa Funato'Correspondence information about the author Hiromasa Funato, Mikio Hoshino

MicroRNA‐19 restores vascular endothelial cell function in lower limb ischemia‐reperfusion injury through the KLF10‐dependent TGF‐β1/Smad signaling pathway in rats
Cell BiologyИюн 28 2018Journal of Biological Biochemistry & Molecular Biology

Yong‐Le Xu, Min‐Hong Zhang, Wei Guo, Yan Xue, Xin Du, Tao Zhang, Na Wu, Ye Wu

pH sensitive liposomes delivering tariquidar and doxorubicin to overcome multidrug resistance of resistant ovarian cancer cells
PharmacologyCancer & ImmunologyИюн 27 2018Colloids and Surfaces B: Biointerfaces

Yuqiong Xia, Mei Fang, Jingyu Dong, Chunzhong Xu, Zhen Liao, Pengbo Ning, Qi Zeng

S100B promotes chemoresistance in ovarian cancer stem cells by regulating p53
Cancer & ImmunologyИюн 27 2018Oncology Reports

Tao Yang, Jianan Cheng, Junhao You, Bing Yan, Hui Liu, Fang Li

RGB-color intensiometric indicators to visualize spatiotemporal dynamics of ATP in single cells
Biochemistry & Molecular BiologyИюн 27 2018Angewandte Chemie International Edition

Satoshi Arai, Rókus Kriszt, Kazuki Harada, Liang-Sheng Looi, Shogo Matsuda, Devina Wongso, Satoshi Suo, Shoichi Ishiura, Yu-Hua Tseng, Michael Raghunath, Toshiro Ito, Takashi Tsubo, Tetsuya Kitaguchi

A dopaminergic switch for fear to safety transitions
NeuroscienceИюн 27 2018Nature Communications

Ray Luo, Akira Uematsu, Adam Weitemier, Luca Aquili, Jenny Koivumaa, Thomas J. McHugh & Joshua P. Johansen

Differentiating cells mechanically limit the interkinetic nuclear migration of progenitor cells to secure apical cytogenesis
Developmental BiologyИюн 26 2018Development

Yuto Watanabe, Takumi Kawaue, Takaki Miyata

Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial Cells
Cancer & ImmunologyИюн 26 2018Cell Reports

Hirotaka Watanabe, Kojiro Ishibashi, Hiroki Mano, Sho Kitamoto, Nanami Sato, Kazuya Hoshiba, Mugihiko Kato, Fumihiko Matsuzawa, Yasuto Takeuchi, Takanobu Shirai, Susumu Ishikawa, Yuka Morioka, Toshiaki Imagawa, Kazuyasu Sakaguchi, Suguru Yonezawa, Shunsuke Kon, and Yasuyuki Fujita

Formation of arrays of planar, murine, intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone
Biomedical ResearchИюн 26 2018Lab on a Chip

Raehyun Kim, Yuli Wang, Shee-Hwan J. Hwang, Peter J. Attayek, Nicole M. Smiddy, Mark I. Reed, Christopher E. Sims and Nancy L. Allbritton

An optogenetic approach to control protein localization during embryogenesis of the sea urchin
Developmental BiologyИюн 26 2018Developmental Biology

Alicia Uchida, Mamiko Yajima

OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses
NeuroscienceИюн 25 2018PLoS Genetics

Sayaka Hori, Shigekazu Oda, Yuji Suehiro, Yuichi Iino, Shohei Mitani

Ribosomal protein L10A and signaling pathway
Cell BiologyИюн 25 2018ScienceDirect

Netnapa Chaichanit, Monwadee Wonglapsuwan, Wilaiwan Chotigeat

Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis
Cancer & ImmunologyИюн 25 2018Nature Medicine

Peter Savas, Balaji Virassamy, Chengzhong Ye, Agus Salim, Christopher P. Mintoff, Franco Caramia, Roberto Salgado, David J. Byrne, Zhi L. Teo, Sathana Dushyanthen, Ann Byrne, Lironne Wein, Stephen J. Luen, Catherine Poliness, Sophie S. Nightingale, Anita S. Skandarajah, David E. Gyorki, Chantel M. Thornton, Paul A. Beavis, Stephen B. Fox, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab), Phillip K. Darcy, Terence P. Speed, Laura K. Mackay, Paul J. Neeson & Sherene Loi

Enhancing Passive Transport of Micro/Nano Particles into Cells by Oxidized Carbon Black
Biochemistry & Molecular BiologyИюн 25 2018ACS Omega

Kittima Amornwachirabodee, Supaporn Khramchantuk, Prompong Pienpinijtham, Nipan Israsena, Tanapat Palaga, and Supason Wanichwecharungruang

PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy
Cell BiologyИюн 22 2018Cell Research

Liming Wang, Yik-Lam Cho, Yancheng Tang, Jigang Wang, Jung-Eun Park, Yajun Wu, Chunxin Wang, Yan Tong, Ritu Chawla, Jianbin Zhang, Yin Shi, Shuo Deng, Guang Lu, Yihua Wu, Hayden Weng-Siong Tan, Pornteera Pawijit, Grace Gui-Yin Lim, Hui-Ying Chan, Jingzi Zhang, Lei Fang, Hanry Yu, Yih-Cherng Liou, Mallilankaraman Karthik, Boon-Huat Bay, Kah-Leong Lim, Siu-Kwan Sze, Celestial T. Yap, and Han-Ming Shen

Functional domains of NEAT1 architectural lncRNA induce paraspeckle assembly through phase separation
Cell BiologyИюн 21 2018Molecular Cell

Tomohiro Yamazaki, Sylvie Souquere, Takeshi Chujo, Simon Kobelke, Yee Seng Chong, Archa H. Fox, Charles S. Bond, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose

Visualizing the Rapid and Dynamic Elimination of Allogeneic T Cells in Secondary Lymphoid Organs
Cancer & ImmunologyИюн 20 2018The Journal of Immunology

Yasuhiro Kanda, Arata Takeuchi, Madoka Ozawa, Yoichi Kurosawa, Toshihiko Kawamura, Dana Bogdanova, Hidekazu Iioka, Eisaku Kondo, Yusuke Kitazawa, Hisashi Ueta, Kenjiro Matsuno, Tatsuo Kinashi and Tomoya Katakai

The PP2A-like Protein Phosphatase Ppg1 and the Far Complex Cooperatively Counteract CK2-Mediated Phosphorylation of Atg32 to Inhibit Mitophagy
Cell BiologyИюн 19 2018Cell Reports

Kentaro Furukawa, Tomoyuki Fukuda, Shun-ichi Yamashita, Tetsu Saigusa, Yusuke Kurihara, Yutaka Yoshida, Hiromi Kirisako, Hitoshi Nakatogawa, and Tomotake Kanki

Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment
Cancer & ImmunologyИюн 19 2018Clinical Cancer Research

Takuya Kato, Kazuhiro Noma, Toshiaki Ohara, Hajime Kashima, Yuki Katsura, Hiroaki Sato, Satoshi Komoto, Ryoichi Katsube, Takayuki Ninomiya, Hiroshi Tazawa, Yasuhiro Shirakawa and Toshiyoshi Fujiwara

MAP1B‐LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules
Cell BiologyИюн 19 2018EMBO Reports

Kohei Arasaki, Haruki Nagashima, Yuri Kurosawa, Hana Kimura, Naoki Nishida, Naoshi Dohmae, Akitsugu Yamamoto, Shigeru Yanagi, Yuichi Wakana, Hiroki Inoue, Mitsuo Tagaya

Monoamines Inhibit GABAergic Neurons in Ventrolateral Preoptic Area That Make Direct Synaptic Connections to Hypothalamic Arousal Neurons
NeuroscienceИюн 18 2018The Journal of Neuroscience

Yuki C. Saito, Takashi Maejima, Mitsuhiro Nishitani, Emi Hasegawa, Yuchio Yanagawa, Michihiro Mieda and Takeshi Sakurai

Elimination of melanoma by sortase A-generated TCR-like antibody-drug conjugates (TL-ADCs) targeting intracellular melanoma antigen MART-1
Biomedical ResearchИюн 15 2018Biomaterials

Jun Lai, Yun Wang, Shan-Shan Wu, Ding Ding, Ze-Yu Sun, Ying Zhang, Jie Zhou, Zhan Zhou, Ying-Chun Xu, Li-Qiang Pan, Shu-Qing Chen

Induction of CD4 T cell memory by local cellular collectivity
Cancer & ImmunologyИюн 15 2018Science

Michal Polonsky, Jacob Rimer, Amos Kern-Perets, Irina Zaretsky, Stav Miller, Chamutal Bornstein, Eyal David, Naama Meira Kopelman, Gil Stelzer, Ziv Porat, Benjamin Chain, Nir Friedman

DNA methylation mediates BmDeaf1-regulated tissue- and stage-specific expression of BmCHSA-2b in the silkworm, Bombyx mori
Cell BiologyИюн 14 2018Epigenetics & Chromatin

Guanfeng Xu, Jie Zhang, Hao Lyu, Qisheng Song, Qili Feng, Hui Xiang and Sichun Zheng

A Decrease in the Proliferative Activity of Human Mesenchymal Stem Cells during Long-Term Cultivation is Not Connected with Change in Their Migration Properties
Stem CellsИюн 13 2018Cell and Tissue Biology

N. F. Mikheeva, P. A. Butylin, A. Yu. Zaritskii, B. V. Popov 

Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder
NeuroscienceИюн 11 2018Molecular Psychiatry

Tomoaki M. Kato, Mie Kubota-Sakashita, Noriko Fujimori-Tonou, Fumihito Saitow, Satoshi Fuke, Akira Masuda, Shigeyoshi Itohara, Hidenori Suzuki, Tadafumi Kato

20‐hydroxyecdysone‐upregulated proteases involved in Bombyx larval fat body destruction
Biochemistry & Molecular BiologyИюн 11 2018Insect Molecular Biology

S.‐Y. Guo, W.‐M. Wu, S.‐Y. Li, Y. Liu, M.‐Q. Ye, Y. Xiao, Y.‐J. Zhong, Y. Cao, K. Li, L. Tian

Ulk2 controls cortical excitatory–inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons
NeuroscienceИюн 08 2018Human Molecular Genetics

Akiko Sumitomo  Hiroshi Yukitake  Kazuko Hirai  Kouta Horike  Keisho Ueta Youjin Chung  Eiji Warabi  Toru Yanagawa  Shiho Kitaoka  Tomoyuki Furuyashiki Shuh Narumiya  Tomoo Hirano  Minae Niwa  Etienne Sibille  Takatoshi Hikida Takeshi Sakurai  Koko Ishizuka  Akira Sawa  Toshifumi Tomoda

Requirement of the 3′-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development
Developmental BiologyИюн 08 2018PLoS Genetics

Kurumi Fukuda, Aki Masuda, Takuma Naka, Atsushi Suzuki, Yuzuru Kato, and Yumiko Saga

Anti-depressant fluoxetine reveals its therapeutic effect via astrocytes
NeuroscienceИюн 08 2018EBioMedicine

Manao Kinoshita, Yuri Hirayama, Kayoko Fujishita, Keisuke Shibata, Youichi Shinozaki, Eiji Shigetomi, Akiko Takeda, Ha Pham Ngoc Le, Hideaki Hayashi, Miki Hiasa, Yoshinori Moriyama, Kazuhiro Ikenaka, Kenji F. Tanaka and Schuichi Koizumi

Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine
Biomedical ResearchИюн 05 2018Nature Communications

Yu Muta, Yoshihisa Fujita, Kenta Sumiyama, Atsuro Sakurai, M. Mark Taketo, Tsutomu Chiba, Hiroshi Seno, Kazuhiro Aoki, Michiyuki Matsuda, Masamichi Imajo

Functional characterization of lysosomal interaction of Akt with VRK2
Developmental BiologyИюн 05 2018Oncogene

Noriyuki Hirata, Futoshi Suizu, Mami Matsuda-Lennikov, Tsutomu Tanaka, Tatsuma Edamura, Satoko Ishigaki, Thoria Donia, Pathrapol Lithanatudom, Chikashi Obuse, Toshihiko Iwanaga & Masayuki Noguchi

The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis
Biomedical ResearchИюн 04 2018Molecular and Cellular Biology

Masatoshi Kobayashi, Mitsuru Ohsugi, Takayoshi Sasako, Motoharu Awazawa, Toshihiro Umehara, Aya Iwane, Naoki Kobayashi, Yukiko Okazaki, Naoto Kubota, Ryo Suzuki, Hironori Waki, Keiko Horiuchi, Takao Hamakubo, Tatsuhiko Kodama, Seiichiro Aoe, Kazuyuki Tobe, Takashi Kadowaki, and Kohjiro Ueki

Perineuronal Nets in the Deep Cerebellar Nuclei Regulate GABAergic Transmission and Delay Eyeblink Conditioning
NeuroscienceИюн 01 2018The Journal of Neuroscience

Moritoshi Hirono, Satoshi Watanabe, Fuyuki Karube, Fumino Fujiyama, Shigenori Kawahara, Soichi Nagao, Yuchio Yanagawa and Hiroaki Misonou

Platelets play an essential role in murine lung development through Clec-2/podoplanin interaction
Cancer & ImmunologyМай 31 2018Blood

Nagaharu Tsukiji Ph.D., Osamu Inoue M.D., Ph.D, Mitsuru Morimoto Ph.D., Norifumi Tatsumi Ph.D., Hiroaki Nagatomo Ph.D., Koji Ueta M.D., Toshiaki Shirai Ph.D., Tomoyuki Sasaki Ph.D., Shimon Otake M.D., Shogo Tamura Ph.D., Toshiaki Tachibana Ph.D, Masataka Okabe M.D., Ph.D, Masanori Hirashima M.D., Ph.D, Yukio Ozaki M.D., Ph.D and Katsue Suzuki-Inoue M.D., Ph.D

DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway
Biomedical ResearchМай 31 2018Cell Death & Differentiation

Yoshinobu Saito, Hayato Hikita, Yasutoshi Nozaki, Yugo Kai, Yuki Makino, Tasuku Nakabori, Satoshi Tanaka, Ryoko Yamada, Minoru Shigekawa, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi & Tetsuo Takehara

Delivery of mitochondriotropic doxorubicin derivatives using self-assembling hyaluronic acid nanocarriers in doxorubicin-resistant breast cancer
PharmacologyМай 31 2018Acta Pharmacologica Sinica

Hui-na Liu, Ning-ning Guo, Wang-wei Guo, Ming-yi Huang-Fu, Mohammad Reza Vakili, Jie-jian Chen, Wen-hong Xu, Qi-chun Wei, Min Han, Afsaneh Lavasanifar & Jian-qing Gao

In vivo reprogramming drives Kras-induced cancer development
Biomedical ResearchМай 25 2018Nature Communications

Hirofumi Shibata, Shingo Komura, Yosuke Yamada, Nao Sankoda, Akito Tanaka, Tomoyo Ukai, Mio Kabata, Satoko Sakurai, Bunya Kuze, Knut Woltjen, Hironori Haga, Yatsuji Ito, Yoshiya Kawaguchi, Takuya Yamamoto & Yasuhiro Yamada

Design, Synthesis, and Evaluation of Novel p-(methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G-Quadruplex
Biochemistry & Molecular BiologyМай 25 2018Journal of Medicinal Biochemistry & Molecular Biology

Wang Peng, Zhi-Yin Sun, Qi Zhang, Sui-Qi Cheng, Shi-Ke Wang, Xiao-Na Wang, Guo-Tao Kuang, Xiao-Xuan Su, Jia-Heng Tan, Zhi-Shu Huang, and Tian-Miao Ou

Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation
Cell BiologyМай 24 2018Nature Communications

Masaki Tsuchiya, Yuji Hara, Masaki Okuda, Karin Itoh, Ryotaro Nishioka, Akifumi Shiomi, Kohjiro Nagao, Masayuki Mori, Yasuo Mori, Junichi Ikenouchi, Ryo Suzuki, Motomu Tanaka, Tomohiko Ohwada, Junken Aoki, Motoi Kanagawa, Tatsushi Toda, Yosuke Nagata, Ryoichi Matsuda, Yasunori Takayama, Makoto Tominaga & Masato Umeda

Arginine-based poly(ester amide) nanoparticle platform: From structure–property relationship to nucleic acid delivery
Biomedical ResearchМай 23 2018Acta Biomaterialia

Xinru You, Zhipeng Gu, Jun Huang, Yang Kang, Chih-Chang Chu, Jun Wu

Ischemic brain injury leads to brain edema via hyperthermia-induced TRPV4 activation
NeuroscienceМай 23 2018The Journal of Neuroscience

Yutaka Hoshi, Kohki Okabe, Koji Shibasaki, Takashi Funatsu, Norio Matsuki, Yuji Ikegaya and Ryuta Koyama

Recurrent 8q24 rearrangement in blastic plasmacytoid dendritic cell neoplasm: association with immunoblastoid cytomorphology, MYC expression, and drug response
Cancer & ImmunologyМай 23 2018Leukemia

Kana Sakamoto, Ryohei Katayama, Reimi Asaka, Seiji Sakata, Satoko Baba, Hideki Nakasone, Sumie Koike, Naoko Tsuyama, Akito Dobashi, Makoto Sasaki, Ryo Ichinohasama, Emi Takakuwa, Rie Yamazaki, Jun Takizawa, Takahiro Maeda, Miwako Narita, Koji Izutsu, Yoshinobu Kanda, Koichi Ohshima & Kengo Takeuchi

Tumor-derived exosomes promote tumor self-seeding in hepatocellular carcinoma by transferring miRNA-25-5p to enhance cell motility
Cancer & ImmunologyМай 22 2018Oncogene

Hao Liu, Wei Chen, Xiao Zhi, En-Jiang Chen, Tao Wei, Jian Zhang, Jian Shen, Li-Qiang Hu, Bin Zhao, Xin-Hua Feng, Xue-Li Bai & Ting-Bo Liang

Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17
Cell BiologyМай 22 2018The Journal of Cell Biology

Takahide Matsui, Peidu Jiang, Saori Nakano, Yuriko Sakamaki, Hayashi Yamamoto, Noboru Mizushima

Neutrophils Provide a Favorable IL-1-Mediated Immunometabolic Niche that Primes GLUT4 Translocation and Performance in Skeletal Muscles
Cancer & ImmunologyМай 22 2018Cell Reports

Masahiro Tsuchiya, Shigenori Sekiai, Hiroyasu Hatakeyama, Masashi Koide, Chayanit Chaweewannakorn, Fukie Yaoita, Koichi Tan-No, Keiichi Sasaki, Makoto Watanabe, Shunji Sugawara, Yasuo Endo, Eiji Itoi, Yoshihiro Hagiwara, Makoto Kanzaki

High-fat Diet-induced Inflammation Accelerates Prostate Cancer Growth via IL6 Signaling
Cancer & ImmunologyМай 18 2018Clinical Cancer Research

Takuji Hayashi, Kazutoshi Fujita, Satoshi Nojima, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Yoshiyuki Yamamoto, Toshiro Kinouchi, Kyosuke Matsuzaki, Kentaro Jingushi, Taigo Kato, Atsunari Kawashima, Akira Nagahara, Takeshi Ujike, Motohide Uemura, Maria Del Carmen Rodriguez Pena, Jennifer B Gordetsky, Eiichi Morii, Kazutake Tsujikawa, George J Netto and Norio Nonomura

Phenotypic diversification by enhanced genome restructuring after induction of multiple DNA double-strand breaks
Plant & Animal ScienceМай 18 2018Nature Communications

Nobuhiko Muramoto, Arisa Oda, Hidenori Tanaka, Takahiro Nakamura, Kazuto Kugou, Kazuki Suda, Aki Kobayashi, Shiori Yoneda, Akinori Ikeuchi, Hiroki Sugimoto, Satoshi Kondo, Chikara Ohto, Takehiko Shibata, Norihiro Mitsukawa & Kunihiro Ohta

Conclusive Evidence for OCT4 Transcription in Human Cancer Cell Lines: Possible Role of a Small OCT4‐Positive Cancer Cell Population
Stem CellsМай 17 2018Stem Cells

Tomoyuki Miyamoto Nobuhiko Mizuno Mitsuko Kosaka Yoko Fujitani Eiji Ohno Aiji Ohtsuka

Conformational Activation of Argonaute by Distinct yet Coordinated Actions of the Hsp70 and Hsp90 Chaperone Systems
Biochemistry & Molecular BiologyМай 17 2018Molecular Cell

Kotaro Tsuboyama, Hisashi Tadakuma'Correspondence information about the author Hisashi TadakumaEmail the author Hisashi Tadakuma, Yukihide Tomari

A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells
MicrobiologyМай 17 2018Cell Host & Microbe

Yoichiro Fujioka, Shinya Nishide, Toyoyuki Ose, Tadaki Suzuki, Izumi Kato, Hideo Fukuhara, Mari Fujioka, Kosui Horiuchi, Aya O. Satoh, Prabha Nepal, Sayaka Kashiwagi, Jing Wang, Mika Horiguchi, Yuko Sato, Sarad Paudel, Asuka Nanbo, Tadaaki Miyazaki, Hideki Hasegawa, Katsumi Maenaka, Yusuke Ohba

Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease
Cancer & ImmunologyМай 17 2018Nature Communications

Masayoshi Ohkuro, Jun-Dal Kim, Yoshikazu Kuboi, Yuki Hayashi, Hayase Mizukami, Hiroko Kobayashi-Kuramochi, Kenzo Muramoto, Manabu Shirato, Fumiko Michikawa-Tanaka, Jun Moriya, Teruya Kozaki, Kazuma Takase, Kenichi Chiba, Kishan Lal Agarwala, Takayuki Kimura, Makoto Kotake, Tetsuya Kawahara, Naoki Yoneda, Shinsuke Hirota, Hiroshi Azuma, Nobuko Ozasa-Komura, Yoshiaki Ohashi, Masafumi Muratani, Keiji Kimura, Ieharu Hishinuma & Akiyoshi Fukamizu

A critical neurodevelopmental role for L-type voltage-gated calcium channels in neurite extension and radial migration
NeuroscienceМай 17 2018The Journal of Neuroscience

Satoshi Kamijo, Yuichiro Ishii, Shin-ichiro Horigane, Kanzo Suzuki, Masamichi Ohkura, Junichi Nakai, Hajime Fujii, Sayaka Takemoto-Kimura and Haruhiko Bito

Engineering of vascularized 3D cell constructs to model cellular interactions through a vascular network
Biomedical ResearchМай 16 2018Biomicrofluidics

Emi Sano, Chihiro Mori, Yuji Nashimoto, Ryuji Yokokawa, Hidetoshi Kotera, and Yu-suke Torisawa

RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6
Developmental BiologyМай 16 2018Nature

Emmanuelle Szenker-Ravi, Umut Altunoglu, Marc Leushacke, Célia Bosso-Lefèvre, Muznah Khatoo, Hong Thi Tran, Thomas Naert, Rivka Noelanders, Amin Hajamohideen, Claire Beneteau, Sergio B. de Sousa, Birsen Karaman, Xenia Latypova, Seher Başaran, Esra Börklü Yücel, Thong Teck Tan, Lena Vlaeminck, Shalini S. Nayak, Anju Shukla, Katta Mohan Girisha, Cédric Le Caignec, Natalia Soshnikova, Zehra Oya Uyguner, Kris Vleminckx, Nick Barker, Hülya Kayserili, & Bruno Reversade

Wolbachia pipientis grows in Saccharomyces cerevisiae evoking early death of the host and deregulation of mitochondrial metabolism
MicrobiologyМай 15 2018MicrobiologyOpen

Cristina Uribe-Alvarez, Natalia Chiquete-Félix, Lilia Morales-García, Arlette Bohórquez-Hernández, Norma Laura Delgado-Buenrostro, Luis Vaca, Antonio Peña, Salvador Uribe-Carvajal

Helical rotation of the diaphanous-related formin mDia1 generates actin filaments resistant to cofilin
Cell BiologyМай 14 2018PNAS

Hiroaki Mizuno, Kotaro Tanaka, Sawako Yamashiro, Akihiro Narita, and Naoki Watanabe

Two-photon imaging of neuronal activity in motor cortex of marmosets during upper-limb movement tasks
NeuroscienceМай 14 2018Nature Communications

Teppei Ebina, Yoshito Masamizu, Yasuhiro R. Tanaka, Akiya Watakabe, Reiko Hirakawa, Yuka Hirayama, Riichiro Hira, Shin-Ichiro Terada, Daisuke Koketsu, Kazuo Hikosaka, Hiroaki Mizukami, Atsushi Nambu, Erika Sasaki, Tetsuo Yamamori & Masanori Matsuzaki

Interleukin-6–mediated trans-signaling inhibits transforming growth factor-β signaling in trabecular meshwork cells
Biochemistry & Molecular BiologyМай 11 2018The Journal of Biological Chemistry

Miyuki Inoue-Mochita, Toshihiro Inoue, Sachi Kojima, Akiko Futakuchi, Tomokazu Fujimoto, Saori Sato-Ohira, Utako Tsutsumi, and Hidenobu Tanihara

Integration of two RAB5 groups during endosomal transport in plants
Plant & Animal ScienceМай 11 2018eLife

Emi Ito, Kazuo Ebine, Seung-won Choi, Sakura Ichinose, Tomohiro Uemura, Akihiko Nakano, Takashi Ueda

The highly metastatic nature of uterine cervical/endometrial cancer displaying tumor-related leukocytosis: clinical and preclinical investigations
Cancer & ImmunologyМай 11 2018Clinical Cancer Research

Tomoyuki Sasano, Seiji Mabuchi, Katsumi Kozasa, Hiromasa Kuroda, Mahiru Kawano, Ryoko Takahashi, Naoko Komura, Eriko Yokoi, Yuri Matsumoto, Kae Hashimoto, Kenjiro Sawada, Eiichi Morii and Tadashi Kimura

Nuclear transport adapts to varying heat stress in a multistep mechanism
Cell BiologyМай 10 2018The Journal of Cell Biology

Yutaka Ogawa, Naoko Imamoto

Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation
NeuroscienceМай 09 2018Nature Communications

Nobuko Inoue, Hirofumi Nishizumi, Hiromi Naritsuka, Hiroshi Kiyonari & Hitoshi Sakano

Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly
Developmental BiologyМай 09 2018eLife

Hiroshi Yamaguchi, Toshiyuki Oda, Masahide Kikkawa, Hiroyuki Takeda

Overlapping function of klf family targets multiple transcription factors to maintain naïve pluripotency of ES cells
Developmental BiologyМай 08 2018Development

Mariko Yamane, Satoshi Ohtsuka, Kumi Matsuura, Akira Nakamura, Hitoshi Niwa

Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling
Biochemistry & Molecular BiologyМай 08 2018EMBO Reports

Koji Kikuchi, Akira Nakamura, Masaki Arata, Dongbo Shi, Mami Nakagawa, Tsubasa Tanaka, Tadashi Uemura, Toshihiko Fujimori, Akira Kikuchi, Akiyoshi Uezu, Yasuhisa Sakamoto, Hiroyuki Nakanishi

Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the anti-tumor effects of aldehyde dehydrogenase
Cancer & ImmunologyМай 07 2018Cancer Research

Naoya Matsunaga, Takashi Ogino, Yukinori Hara, Takahiro Tanaka, Satoru Koyanagi and Shigehiro Ohdo

Trans-2-[4-(dimethylamino)styryl]-3-ethyl-1,3-benzothiazolium perchlorate - New fluorescent dye for testing of amyloid fibrils and study of their structure
Biochemistry & Molecular BiologyМай 04 2018Dyes and Pigments

Anna I. Sulatskaya, Maksim I. Sulatsky, Olga I. Povarova, Natalia P. Rodina, Irina M. Kuznetsova, Alexander A. Lugovskii, Evgeniy S. Voropay, Andrei V. Lavysh, Alexander A. Maskevich, Konstantin K. Turoverov

Intra-organ regulation of shade responses
Plant & Animal ScienceМай 04 2018Plant Physiology

Sujung Kim, Nobuyoshi Mochizuki, Ayumi Deguchi, Atsushi J Nagano, Tomomi Suzuki, Akira Nagatani

Morphological changes of plasma membrane and protein assembly during clathrin-mediated endocytosis
BioimagingМай 03 2018PLoS Biology

Aiko Yoshida, Nobuaki Sakai, Yoshitsugu Uekusa, Yuka Imaoka, Yoshitsuna Itagaki, Yuki Suzuki, Shige H. Yoshimura

Region-specific deletions of the glutamate transporter GLT1 differentially affect nerve injury-induced neuropathic pain in mice
NeuroscienceМай 03 2018Glia

Zhuoyang Zhao  Yuichi Hiraoka  Hiroshi Ogawa  Kohichi Tanaka

Glycosylation controls cooperative PECAM-VEGFR2-β3 integrin functions at the endothelial surface for tumor angiogenesis
Cancer & ImmunologyМай 02 2018Oncogene

Rie Imamaki, Kazuko Ogawa, Yasuhiko Kizuka, Yusuke Komi, Soichi Kojima, Norihiro Kotani, Koichi Honke, Takashi Honda, Naoyuki Taniguchi & Shinobu Kitazume

Corticospinal circuits from the sensory and motor cortex differentially regulate skilled movements through distinct spinal interneurons.
NeuroscienceМай 01 2018Cell Reports

Masaki Ueno, Yuka Nakamura, Jie Li, Zirong Gu, Jesse Niehaus, Mari Maezawa, Steven A Crone, Martyn Goulding, Mark L Baccei, Yutaka Yoshida

Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9
Cell BiologyАпр 30 2018Nucleic Acids Research

Hua Huang, Katannya Kapeli, Wenhao Jin, Yuk Peng Wong, Thiruma Valavan Arumugam, Joanne Huifen Koh, Sumitra Srimasorn, Karthik Mallilankaraman, John Jia En Chua, Gene W. Yeo, and Tuck Wah Soong

Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance
NeuroscienceАпр 30 2018Nature Neuroscience

Taka-aki Koshimizu, Kenji Honda, Sachi Nagaoka-Uozumi, Atsuhiko Ichimura, Ikuo Kimura, Michio Nakaya, Nobuya Sakai, Katsushi Shibata, Kentarou Ushijima, Akio Fujimura, Akira Hirasawa, Hitoshi Kurose, Gozoh Tsujimoto, Akito Tanoue & Yukio Takano

Green monomeric photosensitizing fluorescent protein for photo-inducible protein inactivation and cell ablation
BioimagingАпр 30 2018BMC Biology

Yemima Dani Riani, Tomoki Matsuda, Kiwamu Takemoto and Takeharu Nagai

Uncoordinated centrosome cycle underlies the instability of non-diploid somatic cells in mammals
Cell BiologyАпр 30 2018The Journal of Cell Biology

Kan Yaguchi, Takahiro Yamamoto, Ryo Matsui, Yuki Tsukada, Atsuko Shibanuma, Keiko Kamimura, Toshiaki Koda, Ryota Uehara

Synthesis of a selective ratiometric fluorescent probe based on Naphthalimide and its application in human cytochrome P450 1A
Biochemistry & Molecular BiologyАпр 27 2018Talanta

Xiuxuan Zhang, Yan Zhou, Xiaofei Gu, Yu Cheng, Manxin Hong, Liqiang Yan, Fulong Ma, Zhengjian Qi

Synthesis of a selective ratiometric fluorescent probe based on Naphthalimide and its application in human cytochrome P450 1A
Biochemistry & Molecular BiologyАпр 27 2018Talanta

Xiuxuan Zhang, Yan Zhou, Xiaofei Gu, Yu Cheng, Manxin Hong, Liqiang Yan, Fulong Ma, Zhengjian Qi

Mutations in COA7 cause spinocerebellar ataxia with axonal neuropathy
NeuroscienceАпр 27 2018Brain

Yujiro Higuchi  Ryuta Okunushi  Taichi Hara  Akihiro Hashiguchi  Junhui Yuan Akiko Yoshimura  Kei Murayama  Akira Ohtake  Masahiro Ando  Yu Hiramatsu Satoshi Ishihara  Hajime Tanabe  Yuji Okamoto  Eiji Matsuura  Takehiro Ueda Tatsushi Toda  Sumimasa Yamashita  Kenichiro Yamada  Takashi Koide  Hiroaki Yaguchi Jun Mitsui  Hiroyuki Ishiura  Jun Yoshimura  Koichiro Doi  Shinichi Morishita  Ken Sato Masanori Nakagawa  Masamitsu Yamaguchi  Shoji Tsuji  Hiroshi Takashima

Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress
Stem CellsАпр 26 2018Cell Stem Cell

Yuko Tadokoro'Correspondence information about the author Yuko TadokoroEmail the author Yuko Tadokoro, Takayuki Hoshii, Satoshi Yamazaki, Koji Eto, Hideo Ema, Masahiko Kobayashi, Masaya Ueno, Kumiko Ohta, Yuriko Arai, Eiji Hara, Kenichi Harada, Masanobu Oshima, Hiroko Oshima, Fumio Arai, Akihiko Yoshimura, Hiromitsu Nakauchi'Correspondence information about the author Hiromitsu NakauchiEmail the author Hiromitsu Nakauchi, Atsushi Hirao

Identification of a neuronal population in the telencephalon essential for fear conditioning in zebrafish
Developmental BiologyАпр 25 2018BMC Biology

Pradeep Lal, Hideyuki Tanabe, Maximiliano L. Suster, Deepak Ailani, Yuri Kotani, Akira Muto, Mari Itoh, Miki Iwasaki, Hironori Wada, Emre Yaksi and Koichi Kawakami

Novel Insights into Staphylococcus aureus Deep Bone Infections: the Involvement of Osteocytes
MicrobiologyАпр 24 2018mBio

Dongqing Yang, Asiri R. Wijenayaka, Lucian B. Solomon, Stephen M. Pederson, David M. Findlay, Stephen P. Kidd, Gerald J. Atkins

Bioactivity, Safety, and Efficacy of Amphotericin B Nanomicellar Aerosols Using Sodium Deoxycholate Sulfate as the Lipid Carrier
PharmacologyАпр 24 2018AAPS PharmSciTech

Faisal Usman, Ruqaiya Khalil, Zaheer Ul-Haq, Titpawan Nakpheng, and Teerapol Srichana

GABAergic local interneurons shape female fruit fly response to mating songs
NeuroscienceАпр 24 2018The Journal of Neuroscience

Daichi Yamada, Hiroshi Ishimoto, Xiaodong Li, Tsunehiko Kohashi, Yuki Ishikawa and Azusa Kamikouchi

Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues
Cancer & ImmunologyАпр 24 2018Cell Reports

Ayana Sasaki, Takahiro Nagatake, Riku Egami, Guoqiang Gu, Ichigaku Takigawa, Wataru Ikeda, Tomoya Nakatani, Jun Kunisawa, Yasuyuki Fujita

PPi level regulation by H+-PPase & soluble Ppases
Plant & Animal ScienceАпр 24 2018The Plant Cell

Shoji Segami, Takaaki Tomoyama, Shingo Sakamoto, Shizuka Gunji, Mayu Fukuda, Satoru Kinoshita, Nobutaka Mitsuda, Ali Ferjani, Masayoshi Maeshima

Bioactivity, Safety, and Efficacy of Amphotericin B Nanomicellar Aerosols Using Sodium Deoxycholate Sulfate as the Lipid Carrier
PharmacologyАпр 24 2018AAPS PharmSciTech

Faisal Usman, Ruqaiya Khalil, Zaheer Ul-Haq, Titpawan Nakpheng, and Teerapol Srichana

Novel Insights into Staphylococcus aureus Deep Bone Infections: the Involvement of Osteocytes
MicrobiologyАпр 24 2018mBio

Dongqing Yang, Asiri R. Wijenayaka, Lucian B. Solomon, Stephen M. Pederson, David M. Findlay, Stephen P. Kidd, Gerald J. Atkins

Cutting Edge: Identification of Marginal Reticular Cells as Phagocytes of Apoptotic B Cells in Germinal Centers
Cancer & ImmunologyАпр 23 2018The Journal of Immunology

Kazuki Sato, Shin-ichiro Honda, Akira Shibuya and Kazuko Shibuya

COBLL1 modulates cell morphology and facilitates androgen receptor genomic binding in advanced prostate cancer
Cancer & ImmunologyАпр 23 2018PNAS

Ken-ichi Takayama, Takashi Suzuki, Tetsuya Fujimura, Satoru Takahashi and Satoshi Inoue

WUSCHEL-RELATED HOMEOBOX4 acts as a key regulator in early leaf development in rice
Developmental BiologyАпр 23 2018PLoS Genetics

Yukiko Yasui, Yoshihiro Ohmori, Yumiko Takebayashi, Hitoshi Sakakibara, Hiro-Yuki Hirano

Elasticity-based boosting of neuroepithelial nucleokinesis via indirect energy transfer from mother to daughter
Developmental BiologyАпр 20 2018PLoS Biology

Tomoyasu Shinoda, Arata Nagasaka, Yasuhiro Inoue, Ryo Higuchi, Yoshiaki Minami, Kagayaki Kato, Makoto Suzuki, Takefumi Kondo, Takumi Kawaue, Kanako Saito, Naoto Ueno, Yugo Fukazawa, Masaharu Nagayama, Takashi Miura, Taiji Adachi, Takaki Miyata

FGF2 Has Distinct Molecular Functions from GDNF in the Mouse Germline Niche
Stem CellsАпр 19 2018Stem Cell Reports

Kaito Masaki, Mizuki Sakai, Shunsuke Kuroki, Jun-Ichiro Jo, Kazuo Hoshina, Yuki Fujimori, Kenji Oka, Toshiyasu Amano, Takahiro Yamanaka, Makoto Tachibana, Yasuhiko Tabata, Tanri Shiozawa, Osamu Ishizuka, Shinichi Hochi, Seiji Takashima

The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture
Biochemistry & Molecular BiologyАпр 19 2018The Journal of Biological Chemistry

Chika Takahashi, Koichi Miyatake, Morioh Kusakabe, and Eisuke Nishida

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
Biomedical ResearchАпр 19 2018Nature Communications

Megumi Shiota, Masayuki Naya, Takehiro Yamamoto, Takako Hishiki, Takeharu Tani, Hiroyuki Takahashi, Akiko Kubo, Daisuke Koike, Mai Itoh, Mitsuyo Ohmura, Yasuaki Kabe, Yuki Sugiura, Nobuyoshi Hiraoka, Takayuki Morikawa, Keiyo Takubo, Kentaro Suina, Hideaki Nagashima, Oltea Sampetrean, Osamu Nagano, Hideyuki Saya, Shogo Yamazoe, Hiroyuki Watanabe & Makoto Suematsu

A spherical aberration-free microscopy system for live brain imaging
BioimagingАпр 18 2018Biochemical and Biophysical Research Communications

Yoshihiro Ue, Hiromu Monai, Kaori Higuchi, Daisuke Nishiwaki, Tetsuya Tajima, Kenya Okazaki, Hiroshi Hama, Hajime Hirase and Atsushi Miyawaki

Extracellular Loop Structures in Silkworm ABCC Transporters Determine their Specificities for Bacillus thuringiensis Cry Toxins
Biochemistry & Molecular BiologyАпр 17 2018The Journal of Biological Chemistry

Haruka Endo, Shiho Tanaka, Satomi Adegawa, Fumika Ichino, Hiroko Tabunoki, Shingo Kikuta, and Ryoichi Sato

Jageum-Jung improves 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and suppresses pro-inflammatory chemokine production by inhibiting TNF-α/IFN-γ-induced STAT-1 and NFκB signaling in HaCaT cells
Cancer & ImmunologyАпр 14 2018Journal of Ethnopharmacology

Ju-Hye Yang, Hyun Ju Do, Esther Lee, Nam-Hui Yim, Won-Kyung Cho, Kwang-Il Park, Jin Yeul Ma

Jageum-Jung improves 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and suppresses pro-inflammatory chemokine production by inhibiting TNF-α/IFN-γ-induced STAT-1 and NFκB signaling in HaCaT cells
Cancer & ImmunologyАпр 14 2018Journal of Ethnopharmacology

Ju-Hye Yang, Hyun Ju Do, Esther Lee, Nam-Hui Yim, Won-Kyung Cho, Kwang-Il Park, Jin Yeul Ma

Micro- and Nano-structured 3D Printed Titanium Implants with Hydroxyapatite Coating for Improved Osseointegration
Biochemistry & Molecular BiologyАпр 13 2018Journal of Materials Chemistry B

Qin Jie, Dongqing Yang, Shaheer Maher, Luis lima-marques, Yanmin Zhou, Yujie Chen, Gerald J Atkins and Dusan Losic

A BODIPY disulfonate near-infrared fluorescence-enhanced probe: synthesis, high selectivity to endogenous glutathione and two-photon fluorescent turn-on through thiol-induced SNAr substitution
Biochemistry & Molecular BiologyАпр 13 2018Journal of Materials Chemistry B

Xiang Xia, Ying Qian and Baoxing Shen  

A BODIPY disulfonate near-infrared fluorescence-enhanced probe: synthesis, high selectivity to endogenous glutathione and two-photon fluorescent turn-on through thiol-induced SNAr substitution
Biochemistry & Molecular BiologyАпр 13 2018Journal of Materials Biochemistry & Molecular Biology B

Xiang Xia, Ying Qian and Baoxing Shen  

Micro- and Nano-structured 3D Printed Titanium Implants with Hydroxyapatite Coating for Improved Osseointegration
Biochemistry & Molecular BiologyАпр 13 2018Journal of Materials Biochemistry & Molecular Biology B

Qin Jie, Dongqing Yang, Shaheer Maher, Luis lima-marques, Yanmin Zhou, Yujie Chen, Gerald J Atkins and Dusan Losic

Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury
Stem CellsАпр 12 2018Cell Stem Cell

Aleksandra Tata, Yoshihiko Kobayashi, Ryan D. Chow, Jasmine Tran, Avani Desai, Abdull J. Massri, Timothy J. McCord, Michael Dee Gunn, Purushothama Rao Tata

Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury
Stem CellsАпр 12 2018Cell Stem Cell

Aleksandra Tata, Yoshihiko Kobayashi, Ryan D. Chow, Jasmine Tran, Avani Desai, Abdull J. Massri, Timothy J. McCord, Michael Dee Gunn, Purushothama Rao Tata

Nucleosomes of polyploid trophoblast giant cells mostly consist of histone variants and form a loose chromatin structure
Cell BiologyАпр 11 2018Scientific Reports

Koji Hayakawa, Kanae Terada, Tomohiro Takahashi, Hidehiro Oana, Masao Washizu, Satoshi Tanaka

TGFβ signaling related genes are involved in hormonal mediation during termite soldier differentiation
Plant & Animal ScienceАпр 11 2018PLoS Genetics

Yudai Masuoka, Hajime Yaguchi, Kouhei Toga, Shuji Shigenobu, Kiyoto Maekawa

Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs
Stem CellsАпр 11 2018Nature Communications

Takashi Ikeda, Takafusa Hikichi, Hisashi Miura, Hirofumi Shibata, Kanae Mitsunaga, Yosuke Yamada, Knut Woltjen, Kei Miyamoto, Ichiro Hiratani, Yasuhiro Yamada, Akitsu Hotta, Takuya Yamamoto, Keisuke Okita & Shinji Masui

Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration
Cell BiologyАпр 11 2018Nature Communications

Akihito Harada, Kazumitsu Maehara, Yusuke Ono, Hiroyuki Taguchi, Kiyoshi Yoshioka, Yasuo Kitajima, Yan Xie, Yuko Sato, Takeshi Iwasaki, Jumpei Nogami, Seiji Okada, Tetsuro Komatsu, Yuichiro Semba, Tatsuya Takemoto, Hiroshi Kimura, Hitoshi Kurumizaka & Yasuyuki Ohkawa

SFT-4/Surf4 control ER export of soluble cargo proteins and participate in ER exit site organization
Cell BiologyАпр 11 2018The Journal of Cell Biology

Keiko Saegusa, Miyuki Sato, Nobukatsu Morooka, Taichi Hara, Ken Sato

Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling
Cancer & ImmunologyАпр 10 2018Oncotarget

Victoria R. Barnhouse, Jessica L. Weist, Vasudha C. Shukla, Samir N. Ghadiali, Douglas A. Kniss, and Jennifer L. Leight

In Vivo Genetic Manipulation of Spermatogonial Stem Cells and Their Microenvironment by Adeno-Associated Viruses
Stem CellsАпр 05 2018Stem Cell Reports

Satoshi Watanabe, Mito Kanatsu-Shinohara, Narumi Ogonuki, Shogo Matoba, Atsuo Ogura, Takashi Shinohara

Direct Control of SPEECHLESS by PIF4 in the High-Temperature Response of Stomatal Development
Plant & Animal ScienceАпр 05 2018Current Biology

On Sun Lau, Zhuojun Song, Zimin Zhou, Kelli A. Davies, Jessica Chang, Xin Yang, Shenqi Wang, Doris Lucyshyn, Irene Hui Zhuang Tay, Philip A. Wigge, Dominique C. Bergmann

Direct Control of SPEECHLESS by PIF4 in the High-Temperature Response of Stomatal Development
Plant & Animal ScienceАпр 05 2018Current Biology

On Sun Lau, Zhuojun Song, Zimin Zhou, Kelli A. Davies, Jessica Chang, Xin Yang, Shenqi Wang, Doris Lucyshyn, Irene Hui Zhuang Tay, Philip A. Wigge, Dominique C. Bergmann

A small peptide modulates stomatal control via abscisic acid in long-distance signalling
Plant & Animal ScienceАпр 04 2018Nature

Fuminori Takahashi, Takehiro Suzuki, Yuriko Osakabe, Shigeyuki Betsuyaku, Yuki Kondo, Naoshi Dohmae, Hiroo Fukuda, Kazuko Yamaguchi-Shinozaki, Kazuo Shinozaki

Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D
Cell BiologyАпр 04 2018The Journal of Biological Chemistry

Kou Motani and Hidetaka Kosako

Intrahepatic bile ducts guide establishment of the intrahepatic nerve network in developing and regenerating mouse liver
Developmental BiologyАпр 03 2018Development

Naoki Tanimizu, Norihisa Ichinohe, Toshihiro Mitaka

Super-long single-molecule tracking reveals dynamic-anchorage-induced integrin function
Biochemistry & Molecular BiologyАпр 02 2018Nature Chemical Biology

Taka A. Tsunoyama, Yusuke Watanabe, Junri Goto, Kazuma Naito, Rinshi S. Kasai, Kenichi G. N. Suzuki, Takahiro K. Fujiwara & Akihiro Kusumi

Identification of an Intra- and Inter-specific Tear Protein Signal in Rodents
NeuroscienceМар 29 2018Current Biology

Mai Tsunoda, Kazunari Miyamichi, Ryo Eguchi, Yasuo Sakuma, Yoshihiro Yoshihara, Takefumi Kikusui, Masayoshi Kuwahara, Kazushige Touhara

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
Cancer & ImmunologyDevelopmental BiologyМар 26 2018Developmental Cell

Purushothama Rao Tata, Ryan D. Chow, Srinivas Vinod Saladi, Aleksandra Tata, Arvind Konkimalla, Anne Bara, Daniel Montoro, Lida P. Hariri, Angela R. Shih, Mari Mino-Kenudson, Hongmei Mou, Shioko Kimura, Leif W. Ellisen, Jayaraj Rajagopal

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
Cancer & ImmunologyDevelopmental BiologyМар 26 2018Developmental Cell

Purushothama Rao Tata, Ryan D. Chow, Srinivas Vinod Saladi, Aleksandra Tata, Arvind Konkimalla, Anne Bara, Daniel Montoro, Lida P. Hariri, Angela R. Shih, Mari Mino-Kenudson, Hongmei Mou, Shioko Kimura, Leif W. Ellisen, Jayaraj Rajagopal

High-Throughput Generation of Durable Droplet Arrays for Single-Cell Encapsulation, Culture, and Monitoring
Biochemistry & Molecular BiologyМар 23 2018Analytical Chemistry

Han Wu, Xinlian Chen, Xinghua Gao, Mengying Zhang, Jinbo Wu, and Weijia Wen

High-Throughput Generation of Durable Droplet Arrays for Single-Cell Encapsulation, Culture, and Monitoring
Biochemistry & Molecular BiologyМар 23 2018Analytical Biochemistry & Molecular Biology

Han Wu, Xinlian Chen, Xinghua Gao, Mengying Zhang, Jinbo Wu, and Weijia Wen

Parathyroid hormone–like hormone induces epithelial-to-mesenchymal transition of intestinal epithelial cells by activating the transcription factor Runx2
Cell BiologyМар 22 2018American Journal of Pathology

Shuying He, Minmin Xue, Cuiping Liu, Fang Xie, Lan Bai 

Parathyroid hormone–like hormone induces epithelial-to-mesenchymal transition of intestinal epithelial cells by activating the transcription factor Runx2
Cell BiologyМар 22 2018American Journal of Pathology

Shuying He, Minmin Xue, Cuiping Liu, Fang Xie, Lan Bai 

Species-Specific Mechanisms of Neuron Subtype Specification Reveal Evolutionary Plasticity of Amniote Brain Development
Developmental BiologyМар 20 2018Cell Reports

Tadashi Nomura, Wataru Yamashita, Hitoshi Gotoh, Katsuhiko Ono

Aortic carboxypeptidase–like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis
Biomedical ResearchМар 19 2018Journal of Clinical Investigation

Toshiaki Teratani, Kengo Tomita, Takahiro Suzuki, Hirotaka Furuhashi, Rie Irie, Makoto Nishikawa, Junji Yamamoto, Toshifumi Hibi, Soichiro Miura, Tohru Minamino, Yuichi Oike, Ryota Hokari, Takanori Kanai

The choroid plexus is an important clock component
NeuroscienceМар 14 2018Nature Communications

Jihwan Myung, Christoph Schmal, Sungho Hong, Yoshiaki Tsukizawa, Pia Rose, Yong Zhang, Michael J Holzman, Erik DeSchutter, Hanspeter Herzel, Grigory Bordyugov, Toru Takumi

Excitatory Neuronal Hubs Configure Multisensory Integration of Slow Waves in Association Cortex
NeuroscienceМар 13 2018Cell Reports

Satoshi Kuroki, Takamasa Yoshida, Hidekazu Tsutsui, Mizuho Iwama, Reiko Ando, Takayuki Michikawa, Atsushi Miyawaki, Toshio Ohshima, Shigeyoshi Itohara

Simple mechanosense and response of cilia motion reveal the intrinsic habits of ciliates
Biochemistry & Molecular BiologyМар 12 2018PNAS

Takuya Ohmura, Yukinori Nishigami, Atsushi Taniguchi, Shigenori Nonaka, Junichi Manabe, Takuji Ishikawa, Masatoshi Ichikawa

The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury
Developmental BiologyМар 09 2018The Journal of Biological Chemistry

Hajime Okada, Minami Yamada, Kenji Kamimoto, Cindy Yuet-Yin Kok, Kota Kaneko, Masatsugu Ema, Atsushi Miyajima, and Tohru Itoh

TRPM2 channel aggravates CNS inflammation and cognitive impairment via activation of microglia in chronic cerebral hypoperfusion
NeuroscienceМар 09 2018The Journal of Neuroscience

Jun Miyanohara, Masashi Kakae, Kazuki Nagayasu, Takayuki Nakagawa, Yasuo Mori, Ken Arai, Hisashi Shirakawa and Shuji Kaneko

Actin as a cytoskeletal basis for cell architecture and a protein essential for ecdysis in Prorocentrum minimum (Dinophyceae, Prorocentrales)
Cell BiologyМар 08 2018Phycological Research

Mariia Berdieva, Ilya Pozdnyakov, Olga Matantseva, Nikolay Knyazev, Sergei Skarlato

Localization of nectin-2α at the boundary between the adjacent somata of the clustered cholinergic neurons and its regulatory role in the subcellular localization of the voltage-gated A-type K+ channel Kv4.2 in the medial habenula
NeuroscienceМар 08 2018Journal of Comparative Neurology

Hajime Shiotani, Muneaki Miyata, Yu Itoh, Shujie Wang, Aika Kaito, Akira Mizoguchi, Miwako Yamasaki, Masahiko Watanabe, Kenji Mandai, Hideki Mochizuki, and Yoshimi Takai

Actin as a cytoskeletal basis for cell architecture and a protein essential for ecdysis in Prorocentrum minimum (Dinophyceae, Prorocentrales)
Cell BiologyМар 08 2018Phycological Research

Mariia Berdieva, Ilya Pozdnyakov, Olga Matantseva, Nikolay Knyazev, Sergei Skarlato

Nesprins and opposing microtubule motors generate a point force that drives directional nuclear motion in migrating neurons
NeuroscienceМар 08 2018Development

You Kure Wu, Hiroki Umeshima, Junko Kurisu, Mineko Kengaku

Localization of nectin-2α at the boundary between the adjacent somata of the clustered cholinergic neurons and its regulatory role in the subcellular localization of the voltage-gated A-type K+ channel Kv4.2 in the medial habenula
NeuroscienceМар 08 2018Journal of Comparative Neurology

Hajime Shiotani, Muneaki Miyata, Yu Itoh, Shujie Wang, Aika Kaito, Akira Mizoguchi, Miwako Yamasaki, Masahiko Watanabe, Kenji Mandai, Hideki Mochizuki, and Yoshimi Takai

Neuronal Origin of the Temporal Dynamics of Spontaneous BOLD Activity Correlation
NeuroscienceМар 07 2018Cerebral Cortex

Teppei Matsui  Tomonari Murakami  Kenichi Ohki

Rab7 knockout unveiled regulated autolysosome maturation induced by glutamine starvation
Cell BiologyМар 07 2018Journal of Cell Science

Yoshihiko Kuchitsu, Yuta Homma, Naonobu Fujita, Mitsunori Fukuda

Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis
Cell BiologyМар 06 2018Autophagy

Junji Yamaguchi, Chigure Suzuki, Tomohisa Nanao, Soichirou Kakuta, Kentarou Ozawa, Isei Tanida, Tatsuya Saitoh, Takehiko Sunabori, Masaaki Komatsu, Keiji Tanaka, Shigeki Aoki, Kenji Sakimura & Yasuo Uchiyama

B-1a lymphocytes promote oligodendrogenesis during brain development
NeuroscienceМар 05 2018Nature Neuroscience

Shogo Tanabe & Toshihide Yamashita

A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing
NeuroscienceМар 05 2018Nature Neuroscience

Tatsuya C. Murakami, Tomoyuki Mano, Shu Saikawa, Shuhei A. Horiguchi, Daichi Shigeta, Kousuke Baba, Hiroshi Sekiya, Yoshihiro Shimizu, Kenji F. Tanaka, Hiroshi Kiyonari, Masamitsu Iino, Hideki Mochizuki, Kazuki Tainaka & Hiroki R. Ueda

Single-molecule analysis of phospholipid scrambling by TMEM16F
Biochemistry & Molecular BiologyМар 05 2018PNAS

Rikiya Watanabe, Takaharu Sakuragi, Hiroyuki Noji and Shigekazu Nagata

Signaling between pancreatic β-cells and macrophages via S100 calcium-binding protein A8 exacerbates β-cell apoptosis and islet inflammation
Biochemistry & Molecular BiologyМар 01 2018The Journal of Biological Chemistry

Hideaki Inoue, Jun Shirakawa, Yu Togashi, Kazuki Tajima, Tomoko Okuyama, Mayu Kyohara, Yui Tanaka, Kazuki Orime, Yoshifumi Saisho, Taketo Yamada, Kimitaka Shibue, Rohit N. Kulkarni, and Yasuo Terauchi

Secondary Degeneration of Auditory Neurons after Topical Aminoglycoside Administration in a Gerbil Model
NeuroscienceМар 01 2018BioMed Research International

Jae-Hun Lee, Min Young Lee, Phil-Sang Chung, and Jae Yun Jung

Antiviral activity of transiently expressed mitochondrial antiviral signaling adapter, MAVS orthologue from Asian seabass
Cancer & ImmunologyМар 01 2018Fish and Shellfish Immunology

Rahul Krishnan, Jeena K, Zahoor Mushtaq, K.U. Shyam, Pani Prasad Kurcheti

Secondary Degeneration of Auditory Neurons after Topical Aminoglycoside Administration in a Gerbil Model
NeuroscienceМар 01 2018BioMed Research International

Jae-Hun Lee, Min Young Lee, Phil-Sang Chung, and Jae Yun Jung

Antiviral activity of transiently expressed mitochondrial antiviral signaling adapter, MAVS orthologue from Asian seabass
Cancer & ImmunologyМар 01 2018Fish and Shellfish Immunology

Rahul Krishnan, Jeena K, Zahoor Mushtaq, K.U. Shyam, Pani Prasad Kurcheti

Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations
NeuroscienceФев 28 2018Nature Communications

Gen-ichi Tasaka, Casey J. Guenthner, Amos Shalev, Omri Gilday, Liqun Luo, Adi Mizrahi

Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations
NeuroscienceФев 28 2018Nature Communications

Gen-ichi Tasaka, Casey J. Guenthner, Amos Shalev, Omri Gilday, Liqun Luo, Adi Mizrahi

Two Parallel Pathways Assign Opposing Odor Valences during Drosophila Memory Formation
Developmental BiologyФев 27 2018Cell Reports

Daisuke Yamazaki, Makoto Hiroi, Takashi Abe, Kazumichi Shimizu, Maki Minami-Ohtsubo, Yuko Maeyama, Junjiro Horiuchi, Tetsuya Tabata

Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin
MicrobiologyCancer & ImmunologyФев 27 2018mBio

Pallab Ghosh, Elizabeth M. Halvorsen, Dustin A. Ammendolia, Nirit Mor-Vaknin, Mary X. D. O’Riordan, John H. Brumell, David M. Markovitz, Darren E. Higgins

Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin
MicrobiologyCancer & ImmunologyФев 27 2018mBio

Pallab Ghosh, Elizabeth M. Halvorsen, Dustin A. Ammendolia, Nirit Mor-Vaknin, Mary X. D. O’Riordan, John H. Brumell, David M. Markovitz, Darren E. Higgins
 

Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis
NeuroscienceФев 26 2018PNAS

Kouki Abe, Hiroko Katsuno, Michinori Toriyama, Kentarou Baba, Tomoyuki Mori, Toshio Hakoshima, Yonehiro Kanemura, Rikiya Watanabe and Naoyuki Inagaki

T-reg cells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration
Cancer & ImmunologyФев 23 2018PNAS

Marisella Panduro, Christophe Benoist, and Diane Mathis

T-reg cells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration
Cancer & ImmunologyФев 23 2018Proceedings of the National Academy of Sciences

Marisella Panduro, Christophe Benoist, and Diane Mathis

Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p
Cell BiologyФев 22 2018Biochemical and Biophysical Research Communications

Qian Xu, Yazhou Cui, Jing Luan, Xiaoyan Zhou, Haiying Li, Jinxiang Han

Mapping the Mouse Cell Atlas by Microwell-Seq
Biomedical ResearchФев 22 2018Cell

Xiaoping Han, Renying Wang, Yincong Zhou, Lijiang Fei, Huiyu Sun, Shujing Lai, Assieh Saadatpour, Zimin Zhou, Haide Chen, Fang Ye, Daosheng Huang, Yang Xu, Wentao Huang, Mengmeng Jiang, Xinyi Jiang, Jie Mao, Yao Chen, Chenyu Lu, Jin Xie, Qun Fang, Yibin Wang, Rui Yue, Tiefeng Li, He Huang, Stuart H. Orkin, Guo-Cheng Yuan, Ming Chen, Guoji Guo

EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase
Cancer & ImmunologyФев 22 2018Nature Communications

Kousuke Kasahara, Hiromasa Aoki, Tohru Kiyono, Shujie Wang, Harumi Kagiwada, Mizuki Yuge, Toshio Tanaka, Yuhei Nishimura, Akira Mizoguchi, Naoki Goshima & Masaki Inagaki

Single cell bioluminescence imaging of deep tissue in freely moving animals
BioimagingФев 22 2018Science

Satoshi Iwano, Mayu Sugiyama, Hiroshi Hama, Akiya Watakabe, Naomi Hasegawa, Takahiro Kuchimaru, Kazumasa Z. Tanaka, Megumu Takahashi, Yoko Ishida, Junichi Hata, Satoshi Shimozono, Kana Namiki, Takashi Fukano, Masahiro Kiyama, Hideyuki Okano, Shinae Kizaka-Kondoh, Thomas J. McHugh, Tetsuo Yamamori, Hiroyuki Hioki, Shojiro Maki, Atsushi Miyawaki

Mapping the Mouse Cell Atlas by Microwell-Seq
BioimagingФев 22 2018Cell

Xiaoping Han, Renying Wang, Yincong Zhou, Lijiang Fei, Huiyu Sun, Shujing Lai, Assieh Saadatpour, Zimin Zhou, Haide Chen, Fang Ye, Daosheng Huang, Yang Xu, Wentao Huang, Mengmeng Jiang, Xinyi Jiang, Jie Mao, Yao Chen, Chenyu Lu, Jin Xie, Qun Fang, Yibin Wang, Rui Yue, Tiefeng Li, He Huang, Stuart H. Orkin, Guo-Cheng Yuan, Ming Chen, Guoji Guo

Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p
Cell BiologyФев 22 2018Biochemical and Biophysical Research Communications

Qian Xu, Yazhou Cui, Jing Luan, Xiaoyan Zhou, Haiying Li, Jinxiang Han

Spine Patterning Is Guided by Segmentation of the Notochord Sheath
Developmental BiologyФев 20 2018Cell Reports

Wopat S, Bagwell J, Sumigray KD, Dickson AL, Huitema LFA, Poss KD, Schulte-Merker S, Bagnat M

Spine Patterning Is Guided by Segmentation of the Notochord Sheath
Developmental BiologyФев 20 2018Cell Reports

Wopat S, Bagwell J, Sumigray KD, Dickson AL, Huitema LFA, Poss KD, Schulte-Merker S, Bagnat M

Neuroprotective effect of Annona glabra extract against ethanol-induced apoptotic neurodegeneration in neonatal rats
NeuroscienceDevelopmental BiologyФев 18 2018Photochemistry and Photobiology, B: Biology

Hongru Ma, Jianfeng Han, Qinchuan Dong

Neuroprotective effect of Annona glabra extract against ethanol-induced apoptotic neurodegeneration in neonatal rats
NeuroscienceDevelopmental BiologyФев 18 2018PhotoBiochemistry & Molecular Biology and Photobiology, B: Biology

Hongru Ma, Jianfeng Han, Qinchuan Dong

High-throughput controllable generation of droplet arrays with low consumption
Materials ScienceФев 16 2018Applied Surface Science

Yinyin Lin, Zhongsheng Wu, Yibo Gao, Jinbo Wu, Weijia Wen

High-throughput controllable generation of droplet arrays with low consumption
Materials ScienceФев 16 2018Applied Surface Science

Yinyin Lin, Zhongsheng Wu, Yibo Gao, Jinbo Wu, Weijia Wen

3′-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells
PharmacologyCancer & ImmunologyФев 15 2018Theranostics

Yan Sun, Yong-Hao Huang, Feng-Ying Huang, Wen-Li Mei, Quan Liu, Cai-Chun Wang, Ying-Ying Lin, Canhua Huang, Yue-Nan Li, Hao-Fu Dai, Guang-Hong Tan

Release of Pro-Inflammatory Cytokines from Muscle and Bone Causes Tenocyte Death in a Novel Rotator Cuff In Vitro Explant Culture Model
Biomedical ResearchФев 15 2018Connective Tissue Research

Brianne K. Connizzo and Alan J. Grodzinsky

Release of Pro-Inflammatory Cytokines from Muscle and Bone Causes Tenocyte Death in a Novel Rotator Cuff In Vitro Explant Culture Model
Biomedical ResearchФев 15 2018Connective Tissue Research

Brianne K. Connizzo and Alan J. Grodzinsky

3′-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells
PharmacologyCancer & ImmunologyФев 15 2018Theranostics

Yan Sun, Yong-Hao Huang, Feng-Ying Huang, Wen-Li Mei, Quan Liu, Cai-Chun Wang, Ying-Ying Lin, Canhua Huang, Yue-Nan Li, Hao-Fu Dai, Guang-Hong Tan

A NIR rhodamine fluorescent chemodosimeter specific for Glutathione: Knoevenagel Condensation, detection of intracellular Glutathione and living cell imaging
Biochemistry & Molecular BiologyФев 13 2018Journal of Materials Biochemistry & Molecular Biology B

Lu Lu Tong  and   Ying Qian 

An evolutionarily conserved NIMA-related kinase directs rhizoid tip growth in the basal land plant Marchantia polymorpha
Developmental BiologyФев 13 2018Development

Kento Otani, Kimitsune Ishizaki, Ryuichi Nishihama, Shogo Takatani, Takayuki Kohchi, Taku Takahashi, Hiroyasu Motose

A NIR rhodamine fluorescent chemodosimeter specific for Glutathione: Knoevenagel Condensation, detection of intracellular Glutathione and living cell imaging
Biochemistry & Molecular BiologyФев 13 2018Journal of Materials Chemistry B

Lu Lu Tong  and   Ying Qian 

Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs
Biochemistry & Molecular BiologyФев 12 2018Nature Communications

Tetsutaro Hayashi, Haruka Ozaki, Yohei Sasagawa, Mana Umeda, Hiroki Danno & Itoshi Nikaido

Glucocorticoid receptor expression in resident and hematopoietic cells in IgG4-related disease
Biomedical ResearchФев 12 2018Modern Pathology

Taku Iguchi, Koji Takaori, Akiko Mii, Yuki Sato, Yasunori Suzuki, Hajime Yoshifuji, Hiroshi Seno, Osamu Ogawa, Koichi Omori, Kazuhisa Bessho, Satoru Kondo, Tomokazu Yoshizaki, Hitoshi Nakashima, Takao Saito, Tsuneyo Mimori, Hironori Haga, Mitsuhiro Kawano & Motoko Yanagita

Lupus-like autoimmune disease caused by a lack of Xkr8, a caspase-dependent phospholipid scramblase
Cancer & ImmunologyФев 12 2018PNAS

Mahiru Kawano and Shigekazu Nagata

DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation
Cancer & ImmunologyФев 09 2018Biochemical and Biophysical Research Communications

Takahiro Tomino, Hirotada Tajiri, Takaaki Tatsuguchia, Takahiro Shirai, Kounosuke Oisaki, Shigeki Matsunaga, Fumiyuki Sanematsu, Daiji Sakata, Tomoharu Yoshizumi, Yoshihiko Maehara, Motomu Kanai, Jean-François Cote, Yoshinori Fukui, Takehito Uruno

DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation
Cancer & ImmunologyФев 09 2018Biochemical and Biophysical Research Communications

Takahiro Tomino, Hirotada Tajiri, Takaaki Tatsuguchia,Takahiro Shirai,Kounosuke Oisaki,Shigeki Matsunaga,Fumiyuki Sanematsu,
Daiji Sakata,Tomoharu Yoshizumi, Yoshihiko Maehara,Motomu Kanai,Jean-François Cote,Yoshinori Fukui,Takehito Uruno

ADAM8 Is an Antigen of Tyrosine Kinase Inhibitor-Resistant Chronic Myeloid Leukemia Cells Identified by Patient-Derived Induced Pluripotent Stem Cells
Cancer & ImmunologyФев 08 2018Stem Cell Reports

Masashi Miyauchi, Junji Koya, Shunya Arai, Sho Yamazaki, Akira Honda, Keisuke Kataoka, Akihide Yoshimi, Kazuki Taoka, Keiki Kumano, Mineo Kurokawa

Hippocampal Ripples Downregulate Synapses
NeuroscienceФев 08 2018Science

Hiroaki Norimoto, Kenichi Makino, Mengxuan Gao, Yu Shikano, Kazuki Okamoto, Tomoe Ishikawa, Takuya Sasaki, Hiroyuki Hioki, Shigeyoshi Fujisawa, Yuji Ikegaya

GTL1 and DF1 regulate root hair growth through transcriptional repression of ROOT HAIR DEFECTIVE 6-LIKE 4 in Arabidopsis
Plant & Animal ScienceФев 08 2018Development

Michitaro Shibata, Christian Breuer, Ayako Kawamura, Natalie M. Clark, Bart Rymen, Luke Braidwood, Kengo Morohashi, Wolfgang Busch, Philip N. Benfey, Rosangela Sozzani, Keiko Sugimoto

Auditory input shapes tonotopic differentiation of Kv1.1 expression in avian cochlear nucleus during late development
NeuroscienceФев 08 2018The Journal of Neuroscience

Nargis Akter, Ryota Adachi, Akitoshi Kato, Ryota Fukaya and Hiroshi Kuba

MYB and MYBL1 in adenoid cystic carcinoma: diversity in the mode of genomic rearrangement and transcripts
Cancer & ImmunologyФев 06 2018Modern Pathology

Yuki Togashi, Akito Dobashi, Seiji Sakata, Yukiko Sato, Satoko Baba, Akira Seto, Hiroki Mitani, Kazuyoshi Kawabata & Kengo Takeuchi

Mitochondrial Ferritin is a HIF1a-Inducible Gene that Protects from Hypoxia‐Induced Cell Death in Brain
Biochemistry & Molecular BiologyФев 05 2018Antioxidants and Redox Signaling

Qiong Wu, Wen-Shuang Wu, Lin Su, Xin Zheng, Wenyue Wu, Paolo Santambrogio, Yujing Gou, Qian Hao, Peina Wang, Yaru Li, Bao-Lu Zhao, Guangjun Nie, Sonia Levi, and Yan-Zhong Chang

Mitochondrial Ferritin is a HIF1a-Inducible Gene that Protects from Hypoxia‐Induced Cell Death in Brain
Biochemistry & Molecular BiologyФев 05 2018Antioxidants and Redox Signaling

Qiong Wu, Wen-Shuang Wu, Lin Su, Xin Zheng, Wenyue Wu, Paolo Santambrogio, Yujing Gou, Qian Hao, Peina Wang, Yaru Li, Bao-Lu Zhao, Guangjun Nie, Sonia Levi, and Yan-Zhong Chang

SIP1, a novel SOS2 interaction protein, is involved in salt-stress tolerance in Arabidopsis
Plant & Animal ScienceФев 04 2018Plant Physiology and Biochemistry

Chuntao Wang, Qian Chen, Nan Xiang, Yuanyuan Liu, Xiangxiang Kong, Yongping Yang, Xiangyang Hu

SIP1, a novel SOS2 interaction protein, is involved in salt-stress tolerance in Arabidopsis
Plant & Animal ScienceФев 04 2018Plant Physiology and BioBiochemistry & Molecular Biology

Chuntao Wang, Qian Chen, Nan Xiang, Yuanyuan Liu, Xiangxiang Kong, Yongping Yang, Xiangyang Hu

Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum
NeuroscienceФев 01 2018Neuron

Naofumi Uesaka, Manabu Abe, Kohtarou Konno, Maya Yamazaki, Kazuto Sakoori, Takaki Watanabe, Tzu-Huei Kao, Takayasu Mikuni, Masahiko Watanabe, Kenji Sakimura and Masanobu Kano

Aberrant astrocyte Ca2+ signals “AxCa signals” exacerbate pathological alterations in an alexander disease model
NeuroscienceЯнв 31 2018Glia

Kozo Saito, Eiji Shigetomi, Rei Yasuda, Ryuichi Sato, Masakazu Nakano, Kei Tashiro, Kenji F. Tanaka, Kazuhiro Ikenaka, Katsuhiko Mikoshiba, Ikuko Mizuta, Tomokatsu Yoshida, Masanori Nakagawa, Toshiki Mizuno and Schuichi Koizumi

Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes
Cell BiologyЯнв 30 2018Journal of Molecular Biology

Gustavo Martínez-Noël, Katja Luck, Simone Kühnle, Alice Desbuleux, Patricia Szajner, Jeffrey T. Galligan, Diana Rodriguez, Leon Zheng, Kathleen Boyland, Flavian Leclere, Quan Zhong, David E. Hill, Marc Vidal, Peter M. Howley

M60-like metalloprotease domain of the Escherichia coli YghJ protein forms amyloid fibrils
Cell BiologyЯнв 30 2018PLOS One

Mikhail V. Belousov, Stanislav A. Bondarev, Anastasiia O. Kosolapova, Kirill S. Antonets, Anna I. Sulatskaya, Maksim I. Sulatsky, Galina A. Zhouravleva, Irina M. Kuznetsova, Konstantin K. Turoverov, Anton A. Nizhnikov

Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes
Cell BiologyЯнв 30 2018Journal of Molecular Biology

Gustavo Martínez-Noël, Katja Luck, Simone Kühnle, Alice Desbuleux, Patricia Szajner, Jeffrey T. Galligan, Diana Rodriguez, Leon Zheng, Kathleen Boyland, Flavian Leclere, Quan Zhong, David E. Hill, Marc Vidal, Peter M. Howley

M60-like metalloprotease domain of the Escherichia coli YghJ protein forms amyloid fibrils
Cell BiologyЯнв 30 2018PLOS One

Mikhail V. Belousov, Stanislav A. Bondarev, Anastasiia O. Kosolapova, Kirill S. Antonets, Anna I. Sulatskaya, Maksim I. Sulatsky, Galina A. Zhouravleva, Irina M. Kuznetsova, Konstantin K. Turoverov, Anton A. Nizhnikov

Synthetic-Molecule/Protein Hybrid Probe with Fluorogenic Switch for Live-Cell Imaging of DNA Methylation
Biochemistry & Molecular BiologyЯнв 30 2018Journal of The American Chemical Society

Yuichiro Hori, Norimichi Otomura, Ayuko Nishida, Miyako Nishiura, Maho Umeno, Isao Suetake, and Kazuya Kikuchi

TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer
Cancer & ImmunologyЯнв 30 2018Oncogene

Ken-ichi Takayama, Takashi Suzuki, Tomoaki Tanaka, Tetsuya Fujimura, Satoru Takahashi, Tomohiko Urano, Kazuhiro Ikeda & Satoshi Inoue

Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology
NeuroscienceЯнв 30 2018Nature Communications

Kyota Fujita, Xigui Chen, Hidenori Homma, Kazuhiko Tagawa, Mutsuki Amano, Ayumu Saito, Seiya Imoto, Hiroyasu Akatsu, Yoshio Hashizume, Kozo Kaibuchi, Satoru Miyano & Hitoshi Okazawa

erminal Nerve GnRH3 Neurons Mediate Slow Avoidance of Carbon Dioxide in Larval Zebrafish
NeuroscienceЯнв 29 2018Cell Reports

Tetsuya Koide, Yoichi Yabuki, Yoshihiro Yoshihara

Identification of a Golgi GPI-N-acetylgalactosamine transferase with tandem transmembrane regions in the catalytic domain
Cell BiologyЯнв 26 2018Nature Communications

Tetsuya Hirata, Sushil K. Mishra, Shota Nakamura, Kazunobu Saito, Daisuke Motooka, Yoko Takada, Noriyuki Kanzawa, Yoshiko Murakami, Yusuke Maeda, Morihisa Fujita, Yoshiki Yamaguchi & Taroh Kinoshita

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