Drug Discovery

Pharmaceutical companies use cell models for their research as an alternative to animal experiments and for more precise evaluation of drug efficacy. In recent years, 3D cell models called spheroids, organoids, and “body-on-a-chip” have been engineered and applied to pharmaceutical research. We provide not only conventional brightfield observation solutions but also confocal microscopes and multiphoton excitation microscopes for deep specimen image acquisition, enabling high-resolution observation of 3D structures. To prepare for cell model construction, it is important to keep the quality and number of cells constant, so we also offer reliable cell culture solutions. Our slide loader system and analysis solutions can acquire high-speed, high-resolution images of an entire section of tissue for high-precision pharmacology and drug efficacy analysis.

Related Applications (16)

Quantifying Confluency of iPS Cell Colonies after Derivation

Importance of Accurate Cell Counting in Differentiation of Nerve Cells: iPS PORTAL, Inc.

Cell Counting–Measuring the Number of Cells in Spheroids

Evaluation of Drug Efficacy–The Response of Spheroids to a Drug

Evaluation of Drug Efficacy–Quantitative Evaluation of Spheroid Size

Analysis of Anticancer Drugs-Targeting the Interior of Spheroids

Response to Drug Treatment-Cell Cycle Analysis of 3D Cell Cultures

Response to Drugs–Inside and Outside of 3D Cell Cultures

Evaluation of Drug Efficacy–The Response of Co-Cultured Spheroids to Drugs

The Response of Mitochondria in Cancer Spheroids to Drugs

Fluorescent Image Analysis–Live Dead Cell Assay of Spheroids

Fluorescent Image Analysis–3D Spheroid Invasion in a Collagen Gel

Fluorescent Image Analysis–Cell Division in Spheroids

3D Time-Lapse Imaging of Spheroids with the FLUOVIEW FV3000 Confocal Microscope: 48-Hour Continuous Observation of Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)

Identifying Collagen Fiber Types I and III Stained with Picrosirius Red Using the BX53 Microscope Equipped with Olympus’ High Luminosity and High Color Rendering LED

Imaging of drug response in drug efficacy assessment

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Solutions for Drug Discovery - Build Your Configuration Clear selected Successfully added visible items to your Bookmarks list View Bookmarks Microscope System/Frame {#} FV3000 Available with either galvanometer-only (FV3000) or hybrid galvanometer/resonant (FV3000RS) scanner configurations Highly efficient and accurate TruSpectral detection on all channels Optimized for live cell imaging with high sensitivity and low phototoxicity Inverted and upright frame options to suit a variety of applications and sample types FV3000 Confocal Laser Scanning Microscope Find out more ChooseSelected   IXplore Live Utilize the Olympus real time controller for physiologically relevant data with minimal cell disturbance Maintain cell viability while imaging with various environmental control options Maintain focus accurately and reliably in time-lapse experiments with TruFocus Discover the real morphology of your cells with Olympus silicone immersion optics IXplore Live Live Cell Imaging Microscope System Find out more ChooseSelected   IXplore Pro Automated multi-dimensional observation with easy experiment set up Boost your statistics with multi-well plate screening Acquire fluorescence panoramic images of large samples, such as brain slices Increase resolution and create optical sections with deconvolution Create 3D optical sections and enhance resolution with TruSight IXplore Pro Automated Microscope System Find out more ChooseSelected   IXplore Spin Rapid and high-resolution confocal imaging with a spinning disk system 3D confocal time-lapse imaging of live cells with less phototoxicity and bleaching Precise 3D imaging with improved light collection using X Line objectives Upgrade to the IXplore SpinSR super resolution system depending on your research progress and/or budget IXplore Spin Confocal Imaging Microscope System Find out more ChooseSelected   FVMPE-RS Maximized resolution and contrast in deep imaging with TruResolution objectives High-speed imaging with resonant scanner Extended IR multiphoton excitation up to 1300 nm Triple scanner option for multiphoton and visible light laser stimulation Highly efficient transmission with 1600 nm optical coatings on multiphoton-dedicated objectives and scanning unit 4-axis auto-alignment of IR laser beams FVMPE-RS Multiphoton Laser Scanning Microscope Find out more ChooseSelected   CKX53 Pre-centered phase contrast Inversion contrast (IVC) technique provides clear three-dimensional views. Fluorescence with 3 positions slider Ideal for cell/tissue culture microscope CKX53 Compact Cell Culture Microscope Find out more ChooseSelected   VS200 Outstanding image quality for whole slide imaging, from 2X to 100X Full flexibility in slide sizes and observation methods Simplified and powerful workflow, from brightfield to fluorescence multiplexing Uniquely configurable in software and hardware, from manual brightfield scanning to AI recognition and fully automated scanning VS200 Research Slide Scanner Find out more ChooseSelected   Not Applicable Not Applicable Find out more ChooseSelected   Cameras {#} XM10 1.4 Megapixel monochorome cooled CCD Low noise and high sensitivity Fast Live image speed XM10 Microscope Digital Camera Find out more ChooseSelected   Not Applicable Not Applicable Find out more ChooseSelected   DP23 Share images by DP23-AOU network Clearly observe live images on a large screen Fast high-quality imaging for conferences and teaching DP23 Microscope Digital Camera Find out more ChooseSelected   DP28 4K resolution Color reproduction that rivals the human eye 8.9 megapixel CMOS sensor DP28 Microscope Digital Camera Find out more ChooseSelected   Software {#} cellSens Modular Imaging software platform Intuitive application driven user interface Broad feature set ranging from simple snapshot to advanced multi-dimensional real-time experiments cellSens Imaging Software Find out more ChooseSelected   CKX-CCSW Confluency measurements in unstained culture cells Image-based approach reduces risk of contamination Quick and easy operation CKX-CCSW Confluency Checker Find out more ChooseSelected   NoviSight 3D image recognition from whole structure to sub-cellular Statistical analysis Variety of default assays NoviSight 3D Cell Analysis Software Find out more ChooseSelected   Not Applicable Not Applicable Find out more ChooseSelected   Cell Culture Equipment {#} Not Applicable Not Applicable Find out more ChooseSelected   Cell Counter model R1 Exclusive software for accurate cell counting Innovative autofocusing liquid lens technology User-friendly design Cell Counter model R1 Automated Cell Counter Find out more ChooseSelected   Request a QuoteContact Us Clear selected